
Pet-friendly vacation rentals in Upstate South Carolina
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Upstate South Carolina
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Oakey Mountain Mirror Haus
Nestled in the heart of Clarkesville, GA, Oakey Mountain Mirror Haus offers a tranquil escape where nature meets modern luxury. This cozy, thoughtfully designed tiny home is a haven for those seeking serenity. With reflective exterior walls that blend seamlessly into the lush forest surroundings, you’ll feel at one with nature while enjoying upscale amenities. Perfect for couples or solo travelers, this unique retreat invites you to unwind, recharge, and connect with the beauty of the mountains.

Napaw Mountain Log Cabin~Magical Mt.Top Experience
Welcome to Napaw Mt. Log Cabin! A pet and kid friendly, custom built cabin tucked in 35 acres of hardwoods on a private mountain top.Wrap around decks lend a lovely view of Blue Ridge Mts. Relax in the hot tub(not open Jan/Feb)by the gas fire pit or build a fire in the fireplace on the deck. Lay in the lofts king sz log bed and take in a full window view of nature.The Cabin is only mins from the best hiking, biking, shopping,fine dining in Upstate SC~Table Rock,Pretty Place,Jones Gap,Greenville

Secluded Waterfall Cabin.
Romantic, rustic cabin at the base of a 35-foot waterfall, nestled in the middle of 16 secluded acres surrounded by national forest that extends to the Chattooga River. This magical get-away caters to those with an adventurous spirit. Hike from the cabin to additional waterfalls, bike down Turkey Ridge Road to Opossum Creek Trail and the Five Falls or drive two miles to the Chattooga Belle Farm. The Waterfall Cabin is a joy to us all, and we hope you love it as much as we do. No cleaning fee.

Luxury Retreat & Heated Pool Downtown Simpsonville
Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

TreeTop Dome@CarolinaDomes w Hot Tub near LakeLure
🌿 Luxury Glamping in the Blue Ridge Mountains! Escape to our 30-foot geodesic dome, perched on a sprawling 2000 sq ft deck surrounded by nature. Soak in your private jacuzzi under the stars, unwind in a plush queen bed, and enjoy a cozy loft with two single beds—perfect for families or friends. The dome includes a fully equipped kitchenette, BBQ grill, and all the modern comforts of home with the charm of outdoor living. Book now for a one-of-a-kind experience where peace meets adventure!

Riverfront-10 min Dwtn Gvl-HotTub-GameRm-Sleeps 13
Greenville's riverfront- Sleeps 13 on the Saluda River! This riverfront escape is 10 min to downtown Greenville, 30 min to Clemson, and packed with fun! Enjoy 2 master suites, a bunk room, game room (pool table, arcade, karaoke), hot tub, Sauna, cold plunge firepit, outdoor kitchen, movie screen, kayaks, and more. Close to Falls Park, PKL Pickleball, Paris Mountain & dining. Perfect for families, groups & game-day stays. Launch kayaks right from your home. Book now for the ultimate getaway!

Clemson Lake Hartwell Waterfront, Pontoon Rental
Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

Hide Inn Seek Hillside Treehouse 1.5mi to Main St
Escape to luxury at the Hillside Treehouse brought to you by the biophilic hospitality brand 'Hide Inn Seek'. Located in Highlands NC, just 1.5 miles from main street, this newly built home sits boldly among the trees allowing you to indulge in nature while enjoying luxury accommodations. The 58 step ascent leads you up to a treehouse experience like no other. Check out our newly listed sister property, Bird Nest Treehouse, designed just for couples—complete with a full spa experience!

Huge Views, Outdoor Tub, Fire Pit, Close to Town!
Perched at 4,200' high and under 10 minutes to downtown Highlands and Cashiers, this easily accessed, light filled, cabin offers massive, year-round, long range views of Whiteside &Rock Mountains from every room of the house as well as from our expansive decks! -10 Minutes to Downtown Highlands (shopping, dining, art culture) -8 Minutes to Cashiers Crossroads (Whiteside brewery, coffee, shopping) -5 Minutes to Whiteside Mountain trailhead -15 Minutes to Lake Glenville (Boat Rentals!)

New! Riverfront Tiny Home - Downtown Greenville SC
The River House is a boutique tiny home on the river front of the Saluda with breathtaking views - just 5 minutes from Downtown Greenville! This is a perfect place to relax, unwind, and rejuvenate. Great for a romantic couples getaway, family vacation, or friends getting together to have fun. So cozy and picturesque. You will never want to leave! Located on-site at Saluda Outdoor Center with river tubing tours, 13 Stripes Brewery/Restaurant, live music, fishing and more (within season).

Wooded 3BR Luxury Cabin, Close to City & Nature
Nestled atop the majestic Paris Mountain, this pet-friendly 3 bedroom 2.5 bathroom luxurious retreat promises an unforgettable experience of serenity and natural splendor. Our home stands as an oasis for those seeking an escape from the ordinary. Strategically located, it offers close proximity to Downtown Greenville and the charming Travelers Rest, ensuring guests can effortlessly blend relaxation with exploration. Here, serenity isn’t just a promise; it’s an everyday experience.

Cliffside Cabin at Raven Rock Mountain
🚗 AWD/4WD required to drive to the venue 🥾 No AWD/4WD = steep uphill hike carrying all gear Our cliffside cabin is an immersion into a world where adventure meets serenity, where you'll feel the embrace of nature and the thrill of the extraordinary. Enjoy complete serenity while being just a short drive away from fantastic restaurants, shops, and attractions. ✔ Partially Suspended over a Cliff! ✔ Comfortable Queen Bed + Sofa ✔ Kitchenette ✔ Deck with Scenic Views
Popular amenities for Upstate South Carolina pet-friendly home rentals
Pet-friendly house rentals

Pettigru House: A Historic Boutique Stay Downtown

Fairview Luxury Oasis

Sunset Point-Best view on Broadway - HOT TUB!

Amazing Lakefront home with private NEW dock

Cozy Lakefront 2 bedroom with pool table

Modern Wooded Retreat

Lake Escape

Lakefront Retreat w Views & Dock @ Moonshine Bay
Pet-friendly home rentals with a pool

Cabin in the woods

Pool, King, Fireplace, Lakefront, Kayaks, Firepit

Tranquil escape w/ Pool, Gameoom, Firepit

Pool Gameroom Hot Tub Family Fun Getaway

Beautiful Lake Keowee Condo with great Amenities

Stylish Hotel Room in the Heart of Greenville

College View Cottage & Saltwater Pool

Maggie's Lake House
Private, pet-friendly home rentals

Private Waterfall Apt | No Shared Spaces | pets+

Asheville Luxury Glamping Dome | Mtn View, Hot Tub

Modern Basecamp - Sauna, Pickleball, Solitude

Log Haven at Travelers Rest

The River Gem

The Cottage at Old Oaks Farm

Private Luxury Glamping Dome | Hot Tub & Views

Sunset Mtn Views • Hot Tub • 7 Min to Bryson City
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- Pet-friendly rentals United States
- Clemson University
- Blue Ridge Parkway
- Tryon International Equestrian Center
- Table Rock State Park
- The North Carolina Arboretum
- Chimney Rock State Park
- Gorges State Park
- Devils Fork State Park
- Lake Lure Beach and Water Park
- DuPont State Forest
- Bon Secours Wellness Arena
- Saint Paul Mountain Vineyards
- Jump Off Rock
- Fred W Symmes Chapel
- Fluor Field at the West End
- Jones Gap State Park
- Falls Park On The Reedy
- Peace Center
- Carl Sandburg Home National Historic Site
- Overmountain Vineyards
- Whitewater Falls
- Oconee State Park
- Furman University
- Memorial Stadium, Clemson
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