Apartment vacation rentals in Upstate South Carolina

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Upstate South Carolina

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Top guest favorite

Apartment in Sylva

5 out of 5 average rating, 171 reviews

2 Bedroom Apartment overlooks WCU and Cullowhee NC

This is our 2nd Airbnb at our same mountain top location overlooking Western Carolina University and Cullowhee NC. Listed as being in the top 1% of All Airbnb based on customer satisfaction. The apartment is a 1950 square foot 2-bedroom with a a king-size beds in each bedroom. A full kitchen, a very large living dining kitchen area, a private patio, a gas log fireplace, huge TVs, and a jaw-dropping view of WCU and Cullowhee NC and yes a killer hot tub to soak in the view. The best of everything!

Guest favorite

Apartment in Greenville

4.96 out of 5 average rating, 356 reviews

Straight outta Pinterest w/private balcony

This clean and stylish one bedroom apartment is perfect for the traveling couple or creative businessperson. This rare gem offers an immersive downtown experience with a private balcony viewing the inner city from a local expert's lens. Our unbeatable location features: Self check-in, private parking, (NEW) Ultra Fast Wi-Fi, comfortable bedding & fully-equipped kitchen. It is walking distance to everything GVL is known for making it the perfect location for work, play or maybe an extended stay!

Guest favorite

Apartment in Clayton

4.91 out of 5 average rating, 298 reviews

Blue Moon Vacation Rental 101

Located in beautiful downtown Clayton! Enjoy all that the GA Mountains have to offer. Directly behind Main St restaurants, shops & bars- you won't even need a car! Lake Burton/Lake Rabun short drives. Endless outdoor activities: hiking, biking, rafting. BlackRock State Park & Tallulah Gorge State Park 10 mins away! Great for families/couples! Groups can rent this building for events! washer&dryer/ essentials provided/ WiFi/ smart TV/ 2 bed 1 bath, sleeper sofa Simple check-in, let yourself in!

Superhost

Apartment in Spartanburg

4.86 out of 5 average rating, 232 reviews

Downtown Spartanburg - Morgan Square Apartment

Located across from Morgan Square in Downtown Spartanburg, you'll love the southern charm and shabby chic environment of our 1400 sq ft 2nd floor apartment featuring exposed brick dating over 100 years. Close proximity to downtown dining and shopping including walking distance to Pure Barre headquarters. Nestled between office studios, serene environment for leisure or business stays. Queen bed and sofa. No smoking or pets. (Please note this apartment is on 2nd floor, requiring walking stairs.)

Guest favorite

Apartment in Waynesville

4.91 out of 5 average rating, 186 reviews

Waynesville, NC Apartment ~ Rolling Stone

Come slip into the simple picturesque mountains located in the heart of Historic Waynesville, North Carolina. Our rustic private apartment offers private bedroom, bath and fully equipped kitchen. Your getaway has all the amenities of home while enjoying the serene Appalachia experience. Location is in a central and walk able to the Historic Main Street and Frog Levels which offer an array of local artisans with arts, crafts, local grown food, restaurants and a exquisite variety of boutiques.

Superhost

Apartment in Ashville

4.81 out of 5 average rating, 265 reviews

Charming Bungalow Apartment - Biltmore Area

Newly renovated, cozy and comfortable basement apartment a half mile from Biltmore House and minutes from downtown. Nestled in a quiet neighborhood a few blocks from local breweries, restaurants and shopping. This space has its own private entrance, plenty of light and loads of charm. Great location with easy access to everything you could want. Hosted by a hard-working friendly musician who's been at it for years. Check-out RahmSquad on streaming platforms/socials (spotify, instagram, etc..)

Guest favorite

Apartment in Greenville

4.93 out of 5 average rating, 113 reviews

Destination Overbrook - Luxury Meets Location

Modern, stylish and close to downtown Greenville, this private and secure apartment offers luxury and convenience if you want to be close to town (5 minutes or less). You’ll have granite countertops, stainless steel appliances, designer fixtures, 9 ft. ceilings, and crown molding. Full kitchen, in-unit washer and dryer, ironing board and hair dryer make this a welcome space to use while you visit Greenville for work or play! We've hosted well over 1,000 guests. Let us host YOU next!

Top guest favorite

Apartment in Waynesville

4.93 out of 5 average rating, 246 reviews

Mountain View Sunrise/Sunset 11 mi to Smoky Mtns

You’ll love the Amazing View of 4 mountains ranges including The Great Smoky Mountains only 11 miles away. 9 Miles to Cataloochee! Horses in back. This one level apartment is totally separate from our home which was built as a duplex. Quiet Peaceful. Private Paved road - 10 minutes to downtown Waynesville High Speed Internet! Perfect for a long term rental. Biltmore & Asheville nearby.4 mi to Lake Junaluska, 20 miles to Cherokee. Build a bonfire and enjoy the views!

Guest favorite

Apartment in Hendersonville

4.87 out of 5 average rating, 359 reviews

Downtown Historic Main Street Loft. Offstreet park

Prime location on Hendersonville's pedestrian-friendly Main Street. Three-room apartment in historic building; modern conveniences; special touches. Watch the sunset. Restaurants, entertainment, unique shops just down steps. Off-street parking provided. Jackson Park is located about eight blocks away, complete with walking and biking trails, bird watching, soccer fields, baseball fields, tennis court, basketball and other recreational opportunities. Golf courses abound.

Guest favorite

Apartment in Greenville

4.91 out of 5 average rating, 526 reviews

The Edge on North Main

Located on North Main in downtown Greenville. This 3060 square brick house was built in 1925 and cut into 4 private apartments in 1945. You can walk to the heart of downtown in 15 to 20 minutes. One parking spot at the back of the house. Several restaurants within a 5 to 10 minute walk. Hot grill and food store next door. Free trolley pick up Thurs.- Sun 0.6 miles to The Hyatt Regency 0.7 miles to The Bon Secours Wellness Arena 1.4 miles to Falls Park

Top guest favorite

Apartment in Spartanburg

4.97 out of 5 average rating, 225 reviews

Spartanburg Magazine

FEATURED in the Spartanburg Herald Journal & the Spartanburg Magazine Home & Garden. Morgan Square 1 mi. Fifth Third Park 1.5 mi. Wofford Coll. 1.7 mi., Converse Coll. 2.3 mi. USC 6.1 mi. Spartanburg Reg Hospital 2.7 mi. GSP - Airport 18 mi. NOT SUITABLE FOR INFANTS OR CHILDREN UNDER 12. GUESTS MUST BE AT LEAST 21 UNLESS ACCOMPANIED BY PARENT. 1 Bdrm 1 Ba APARTMENT located on the 2nd floor. Must climb stairs. SMART TV, WiFi.

Top guest favorite

Apartment in Travelers Rest

4.98 out of 5 average rating, 135 reviews

Fantastic 2 BR Apartment in Travelers Rest, SC

Fantastic 2 bedroom fully-equipped apartment in Travelers Rest, SC on a quiet road with great sunsets. Minutes from so many things to do & see- restaurants and bars, shopping, hiking & fishing, the Swamp Rabbit Trail, Furman University, downtown Greenville, there’s even a local rodeo and dirt track racing... There is a reason the greater Greenville, SC area is America’s Coolest New Weekend City- Art, food, and waterfalls as tall as buildings.