Vacation rentals in South Carolina

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in South Carolina

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Top guest favorite
An outdoor space features a round inground pool with a water feature. Surrounding the pool, lounge chairs and colorful seating areas offer relaxation options. A covered outdoor kitchen is seen in the background against a backdrop of palm trees, enhancing the serene setting.
Home in Myrtle Beach
4.96 out of 5 average rating, 163 reviews

Southern Comfort

Vacation in the heart of Myrtle Beach! Situated in a quiet neighborhood just .5 miles to Broadway at the Beach and .75 miles to the ocean. Fully renovated home features 4 bedrooms, 4 bathrooms, comfortably sleeps 8 and boasts a brand-new billiards room perfect for evening entertainment. The private, secluded backyard offers an inground pool, outdoor kitchen, TV, and firepit, with plenty of sun and a covered patio for shade. Several golf courses within 10 minutes. Location...Location...Location!

ValueFamilyLong stay

Top guest favorite
The entrance features large, rustic double doors opening to reveal a stylishly decorated bedroom. A crystal chandelier hangs above a beautifully crafted bed with an intricate headboard. Two decorative topiary plants frame the doorway, adding a touch of greenery to the warm wooden floor.
Treehouse in Waterloo
4.99 out of 5 average rating, 257 reviews

#1 most loved AirBnB in SC! *Old Soul Treehouse*

The Old Soul Treehouse is a fabulous destination for couples looking to have a unique getaway! This is a waterfront treehouse on Lake Greenwood with a private dock, heat/AC, hot tub, king size bed, & a fully equipped kitchen & bathroom. Take a dip in the lake during the day or at night enjoy a soak in the hot tub on the peaceful porch under the stars. Book with us and you will soon be enjoying luxury by the water during this intimate experience with the one you love. We would love to have you!

FamilyLocationHospitality

Top guest favorite
An airy loft space features a suspended wooden swing, inviting relaxation under the high, timbered ceilings. Natural light streams through large windows, illuminating cozy furnishings including a bed and a dining area with a wooden table. Unique decor elements enhance the overall character.
Guesthouse in Summerville
4.98 out of 5 average rating, 774 reviews

★Delightful guest house near historic plantations★

Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

FamilyValueCheckout

Top guest favorite
The cottage is surrounded by greenery, showcasing a welcoming front porch with white railings. Two planters are placed at the entrance, and a swing is visible on the side. The entrance is accessible from a paved pathway leading to the door.
Cottage in Sumter
4.97 out of 5 average rating, 539 reviews

Restful Lakeside Cottage -Dogs allowed

This pond-side cottage is a peaceful place to relax & unwind. Sit in the sunroom and enjoy watching the birds & the water or enjoy the front porch rockers where you can listen to the birds & frogs. We are 12 min. from downtown Sumter & 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens, Poinsett State Park & Congaree Nat. Park. It's only 2 hrs to Myrtle Beach or Charleston & 3 hrs to the mtns. While it's conveniently located, this cottage offers a quiet place to relax.

FamilyValueBreakfast

Top guest favorite
A vibrant scene showcases two golden retrievers playing in a shallow stream, surrounded by lush green foliage. Behind them, a cascading waterfall flows over rocky tiers, creating a soothing sound and enhancing the natural beauty of the forested landscape.
Cabin in Oconee County
4.99 out of 5 average rating, 398 reviews

Secluded Waterfall Cabin.

Romantic, rustic cabin at the base of a 35-foot waterfall, nestled in the middle of 16 secluded acres surrounded by national forest that extends to the Chattooga River. This magical get-away caters to those with an adventurous spirit. Hike from the cabin to additional waterfalls, bike down Turkey Ridge Road to Opossum Creek Trail and the Five Falls or drive two miles to the Chattooga Belle Farm. The Waterfall Cabin is a joy to us all, and we hope you love it as much as we do. No cleaning fee.

ValueFamilyHospitality

Top guest favorite
A treehouse surrounded by trees glows gently with warm lights in the evening. Two Adirondack chairs are positioned around a fire pit, with a small table nearby. The forest setting offers a calm and inviting atmosphere for outdoor relaxation.
Treehouse in Mountain Rest
5.0 out of 5 average rating, 490 reviews

THE BELLA LUNA Romantic Treehouse - Outdoor Shower

This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

LocationValueWalkability

Guest favorite
An outdoor game area features a pool table, with a set of colorful balls arranged on the surface. The scene includes a grassy lawn leading to the water, where a sunset illuminates the landscape. Two red chairs and a picnic-style setup are visible nearby.
Home in Prosperity
4.91 out of 5 average rating, 107 reviews

Sunset Cove-Beautiful Lake views

Your home away from home on Lake Murray! Spacious, modern clean, home with 3 levels of living -3 spacious decks, screen porch, and sunroom all with massive lake views! Plenty to do at Sunset Cove relaxing with family and friends and toys galore! "Wow just wow, best Airbnb ever..Sarah, June 2026. "..clean, beautiful view and so many fun games..Lisa, Oct 2025."Perfect setting for a quiet getaway. The house was amazing, clean, and had all the amenities we were looking for.."Jay, Sept 2025

LocationValueAmenities

Top guest favorite
Tiny home in Batesburg-Leesville
4.98 out of 5 average rating, 127 reviews

Private 75 acre farm with lake

Quiet getaway at Lake Tom-A-Shawna Farm. Fully furnished 2 queen bed, 1 full bath, mini cabin that offers accommodations for traveling professionals, equestrians, and vacationers. This gated private property spans 75 acres, including a 20-acre lake, and features a 4-person cabin with full appliances, granite countertops, high-speed internet, 2 TVs, an electric fireplace, heat/AC, deck. Fishing, shooting, hiking or just relaxing. We offer fresh eggs and meat for purchase.

ValueFamilyLayout

Guest favorite
A dome retreat is perched on a spacious deck surrounded by trees. The structure features a distinctive geometric design with large windows, while colorful bar stools and comfortable outdoor seating offer an inviting space for relaxation. A hot tub is visible nearby, enhancing the outdoor experience.
Dome in Travelers Rest
4.95 out of 5 average rating, 334 reviews

Treetop Getaway w/ Hot Tub • Peaceful retreat

Welcome to Treetop Getaway! Escape to your own enchanting oasis, nestled high among the trees in this stunning dome retreat! Situated on a private 14 acres with a stream running through the middle of the property, this luxurious and cozy hideaway offers the perfect setting for relaxation, reconnection, and rest. Book now and treat yourself to an unforgettable experience filled with comfort, natural beauty, and cherished moments. We can't wait to host you!

FamilyLocationCleanliness

Top guest favorite
A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.
Home in Summerton
4.99 out of 5 average rating, 133 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

ValueLocationHospitality

Top guest favorite
The exterior showcases a striking multi-level mountain villa framed by lush trees. A spacious deck with loungers is visible, complemented by elegant outdoor lighting. The modern architecture features large windows that invite natural light, enhancing the connection with the scenic surroundings.
Home in Greenville
4.94 out of 5 average rating, 101 reviews

Mountain Villa 15min from Downtown Greenville

You'll love the unbelievable sunsets from this one-of-a-kind mountain villa that's just an easy 15 minute drive from downtown Greenville. With sweeping mountain views and luxurious finishes, this home will wow you from every room. The main level has a huge 8x12 accordion door that leads out to the soaring deck with glass rails, perfect for enjoying the sunsets. Elegantly designed, each room of this house is an experience and perfect for your stay.

ValueFamilyHiking

Top guest favorite
Cottage in Saint Helena Island
4.98 out of 5 average rating, 144 reviews

Private Waterfront Retreat w/ Sauna

Escape to The Hideaway, a newly built modern 2BR/2BA waterfront retreat on St. Helena Island. Surrounded by live oaks and sweeping salt marsh views, this architecturally unique cottage blends luxury and nature with curated amenities, including a private indoor sauna. Peaceful and secluded, yet just minutes from beaches, outdoor adventures, local shops, and dining—designed for rest, reconnection, and renewal.

ValueLocationCheck-in

Popular amenities for South Carolina vacation rentals

All about South Carolina

Weeping Spanish moss cloaks the cobblestone streets and historic homes of South Carolina’s oldest cities while its coast beckons travelers from near and far. South Carolina is one of the original 13 colonies of the United States, and it resisted British authority. Perched on the coast just north of Savannah, Charleston has been a major port city since the Spanish first settled the area in the 16th century, and was hotly contested territory in subsequent wars. Remnants of this history still stand in places like Fort Sumter and Fort Moultrie. South Carolina’s draws are heavily clustered around coastal areas like Hilton Head and Myrtle Beach — or on waterways that connect to the sea — but there’s plenty to do and see in its inland cities like the state capital of Columbia and the cultural hotbed of Greenville.

What are the top things to do in South Carolina?

Charleston

With its cobblestone streets and antebellum architecture, Charleston is one of the most charming cities in the American South. A peninsula town whose rivers empty into the Atlantic Ocean, it has a warm, welcoming vibe where visitors are treated like family, and just about anywhere you go somebody is eager to fill your cup with a heavy-handed pour of spiked sweet tea. If you want to combine urban travel with a beach getaway, Charleston is the place for you; its downtown core occupies a tight grid of streets and historic homes with thriving beach communities — Folly Island to the west and Isle of Palms and Sullivan’s Island to the east — on each side.

Congaree National Park

Wildlife enthusiasts, hikers, and paddlers will want to add South Carolina’s only national park, just south of Columbia, to their itinerary. The Congaree and Wateree rivers snake their way through the bottomland hardwood forest, part of the Congaree International Biosphere Reserve, making it a great place to observe the unique ecosystems by kayak via its waterways.

Greenville

In the northwestern corner of the Palmetto State near the Blue Ridge Mountains, Greenville is a melting pot of lifestyles: a city made for epicures and art lovers that also places heavy emphasis on outdoor living. While Falls Park on the Reedy is Greenville’s centerpiece, it’s not the only waterfall in town: Greenville boasts more than 30 breathtaking cascades, three state parks, and the 22-mile, multi-use Prisma Health Swamp Rabbit Trail.

Destinations to explore