Private suite vacation rentals in South Carolina

Find and book unique private suite rentals on Airbnb

Top-rated private suite rentals in South Carolina

Guests agree: these private suite rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

The exterior of the duplex is shown, featuring a well-maintained lawn with fallen leaves and a pathway leading to the entrance. Large windows are visible, allowing natural light, while an American flag adorns the front. A mailbox marked '116' is positioned at the driveway.

Guest suite in Columbia

4.93 out of 5 average rating, 413 reviews

Comfy & Private Left Half of a Duplex

Lexington Permit #2500623 Listing is a private, cozy half duplex. Private entrance, parking in quiet neighborhood. Bathroom has new large shower, towels, shampoo/conditioner, lotion, soap, vanity. Bedroom has queen bed, walk-in closet, large TV. Kitchenette has sofa lounger, microwave, mini fridge, TV, coffee makers (single cup/round pod or ground type), dishes, glasses, silverware. *1 mile from Saluda Shoals Park/ Lake Murray. *4 miles from Columbian Mall - tons of shopping and restaurants.

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Top guest favorite

A spacious brick home is framed by lush greenery, with a warm glow of sunlight filtering through the trees. The structure features multiple gables and large windows, creating an inviting entryway. A manicured driveway leads to the entrance, enhancing the serene natural setting.

Guest suite in Woodruff

4.96 out of 5 average rating, 228 reviews

Luxurious river front nature retreat on 120 acres

Privacy, luxury and nature-for you! Luxurious apartment in our home (owner-occupied) - on 120 private acres overlooking the Enoree river. Visitors are blown away by the view and the sound of the river. Beautiful walking trail and 2 kayaks available for use. There is a beautiful waterfall located only 600 yards upriver, by kayak. There are bald eagles, turtles, herons, etc.. 15 miles to GSP airport and 21 miles to downtown Greenville and Spartanburg. (No pets, smoking/vaping inside, or guns!)

LocationFamilyGetting around

Top guest favorite

The exterior of the guest house features a mix of textured siding and an intricately designed balcony supported by stylish columns. Surrounded by greenery, it includes a circular window and a swing on the porch, inviting relaxation in a tranquil setting.

Guest suite in West Ashley

4.99 out of 5 average rating, 458 reviews

The Garden Folly Guest House

Our architect said, “this is NOT a garage, it’s a Garden Folly!” Our Guest House has a bird’s eye view of the rose covered pecan tree and a vista of the marsh and the Wappoo Creek. When we rebuilt our 1930's garage we saved all the beaded siding and pine floor. My husband enjoyed incorporating many design elements and creative ideas. It was quickly becoming the Taj Garage. We decided it was just the kind of property we enjoy when we travel, so, Voila! we decided to share it with you!

FamilyLocationWifi

Guest favorite

A mid century modern bedroom features a spacious bed adorned with neutral linens. Natural light illuminates the room, highlighting a brick fireplace and decorative wall mirrors. A comfortable seating area with a chair and table, along with lush greenery, enhances the serene atmosphere.

Guest suite in West Ashley

4.9 out of 5 average rating, 591 reviews

Spend the Night in a Photographer's Studio!

This bright and clean mid century modern style bedroom is a great retreat for couples, solo, and business travelers. Some features include dual shower heads, private washer & dryer and cozy seating area. Only 12 minutes to the airport and 4 minutes to I-526, the location is considered “centrally located.” 7 miles from downtown Charleston. 14 miles to Folly Beach. Close to many of the most popular wedding venues, plantations, and all the secret places the LowCountry has to offer.

FamilyLocationLong stay

Top guest favorite

A spacious living area features a large entertainment center with a flat-screen TV, a comfortable leather sofa, and a decorative area rug. A dining table and chairs are positioned nearby, with the kitchenette visible in the background, showcasing a full-size fridge and microwave.

Guest suite in Lake Murray

4.99 out of 5 average rating, 509 reviews

LAKE FRONT SWEET - Dog Friendly

We hope you will find everything you need in our clean, comfortable basement suite. On beautiful Lake Murray and only 8 mins to Chapin with 3 great grocery stores and plenty of restaurants. We are off Amicks Ferry Road @10 mins out of Chapin. Enjoy the lake view from your shady patio or on the dock. There's room for your boat and trailer, and we are dog friendly -1 dog if you agree to our rules. Lexington Cty #2500883. Sorry, 2 guests max, no extra guests day or night.

ValueFamilyDecor

Top guest favorite

Guest suite in McClellanville

4.96 out of 5 average rating, 157 reviews

Resort @ Kit Hall Pool & Gardens, near Charleston

Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

FamilyLocationWalkability

Top guest favorite

A cozy seating area features a light-colored sofa adorned with neutral pillows. Nearby, a well-equipped kitchen with dark green cabinetry is visible, showcasing various kitchen utensils and small appliances. Natural light enters through windows, highlighting the modern design.

Guest suite in Abbeville

5.0 out of 5 average rating, 141 reviews

Walk in studio w laundry and fast wifi

Unwind in your private suite just 5 minutes from Historic Abbeville Square. Sip coffee on the patio, stream shows on the smart TV and sleep soundly in a plush queen bed. What you’ll love: Fast Wi-Fi & keypad self-check-in Fire-pit, creek-side seating & driveway parking Mini-fridge, microwave & starter toiletries Exploring Uptown, mining, catching a show at the Opera House or hiking Lake Russell? We’re the perfect base. Book your stay today!

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Guest favorite

A private deck features a small round table with two blue chairs surrounded by lush greenery. The wooden railing provides an unobstructed view of the neighborhood, enhancing the outdoor setting for relaxation.

Guest suite in James Island

4.91 out of 5 average rating, 238 reviews

Surfer's Studio! Clean Tiny Apt 2 Miles from Beach

Modern, funky studio apartment located between Folly Beach and historic downtown Charleston. The deck overlooking the neighborhood pond is perfect for your morning coffee or a sunset cocktail. Inside is a clean and quiet living space. The ocean, sand, surfers, and dolphins are just 2 miles away, where you can also find great restaurants, shops, music, and the Folly Beach pier. Perfect for couples or a solo traveler.

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Top guest favorite

A private balcony features two comfortable wicker chairs facing a small table, overlooking lush salt marshland. The blue sky is dotted with fluffy clouds, creating a serene backdrop for outdoor relaxation. The wooden flooring complements the natural surroundings, enhancing the tranquil setting.

Guest suite in James Island

5.0 out of 5 average rating, 184 reviews

Marsh view retreat near Folly Beach and Downtown

Welcome to Lighthouse Lookout, a private-entry guest suite, offering a truly unique Charleston experience. Conveniently located on James Island, between Folly Beach and Downtown Charleston. The private balcony provides stunning views of the salt marsh and historic Morris Island Lighthouse. It’s the perfect place to relax and enjoy the changing tides, abundant wildlife, and scenic sunrises.

ValueFamilyQuiet

Top guest favorite

A wooden dock extends over calm water, leading to a serene scene reflected in the surface. Lush greenery surrounds the area, with trees visible in the background against a colorful sky at dusk.

Guest suite in James Island

4.92 out of 5 average rating, 489 reviews

Peaceful Waterfront Home in Charleston

Come enjoy the southern charm of this newly renovated waterfront Charleston home. A luxurious bed and bath have been created here with your comfort and privacy in mind. Located just 5 minutes from historic downtown Charleston, and another 5 minutes from beautiful Folly Beach, you will be perfectly situated for your trip no matter what your vacation entails or how long your stay!

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Guest favorite

A cozy studio space displays a warm seating area with a large, rounded artwork as the backdrop. A natural wood table sits center stage, surrounded by wicker chairs. Sunlight filters through multiple windows, contributing to the inviting atmosphere of the room.

Guest suite in Park Circle

4.93 out of 5 average rating, 266 reviews

Midcentury Studio w Patio in Park Circle

DISCOVER YOUR MIDCENTURY RETREAT IN PARK CIRCLE Welcome to a sunny, beautifully designed studio where midcentury style meets modern bohemian comfort. This is the kind of place where you'll want to linger over morning coffee on your private patio, stretch out during work hours at a dedicated desk, and sink into a luxurious clawfoot tub after exploring Charleston's best neighborhoods.

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Top guest favorite

A serene lakeside view captures a vibrant sunset, reflecting colors across the water. The image includes nearby docks and boat access, framed by tall pine trees. The calm surface of the lake mirrors the gradient sky, enhancing the peaceful atmosphere of the outdoor setting.

Guest suite in Lake Murray

4.95 out of 5 average rating, 146 reviews

Tranquil Guest Apt on Lake Murray w/boat ramp

This charming guest apartment was recently renovated and decorated to provide you with a cozy spot for your get-a-way. Everything you need to make you feel at home is here. Step outside onto the upper deck to enjoy stunning sunset views of the lake. Fishing and boating enthusiasts are welcome and can enjoy easy access to the lake with our private boat ramp and dock

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