
Guesthouse vacation rentals in South Carolina
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Top-rated guesthouse rentals in South Carolina
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
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Popular amenities for South Carolina guesthouse rentals
Family-friendly guest house rentals

Studio Apt - (Pets/beach/pool/golf)
TJ was a very helpful, responsive, and friendly. The space was very enjoyable, great location

Bungalow Under The Oaks
We stayed here for a long weekend and will 100% be back! Along with a very clean house, Jessica had everything needed in the kitchen along with extra bathroom products in case we forgot anything. Even had necessities if you brought your pet! Location was very close to everything and felt very private and a cute getaway for 2.

New Loft in Historic Summerville
We loved our stay at Jacquelynn's! We had to travel with our two older, yet anxious, dogs for a wedding and it turned out to be the perfect place for us. The loft is detached from the home, making it much more private to go to and from. The place was spotless with cute decor. Even though it is a smaller space, she has everything you need to make your stay comfortable. Lots of towels and blankets as well as silverware, coffee pot, and mugs. I was pleasantly surprised at how the bathroom was actually quite spacious for the small space. The most important and best part for us was the peace and quiet. We typically have to worry about outside noise as our dogs will bark at any and every noise they hear. But the loft is nestled in such a quiet and quaint neighborhood, making it perfect for anyone with anxiety ridden dogs. I highly recommend Jacquelynn's loft!

Cozy Park Circle, Charleston Guest House
Very convenient place to Park Circle and the major highways in Charleston.

Home on the farm
Awesome little getaway. From fishing to riding the trails on the property l and splashing around in the pool. It was peaceful. Kids had an awesome time.

Romantic Beach Style Cottage close to everything!
Clean & conscious hosts! Mindful of needs that may crop up, lovely home & family. Flexible! Perfect oasis away from the bustle of Charleston.

Mountain Edge Loft
Beautiful land and home, cute dogs and chickens, the bread was delicious and i definitely recommend California's Mexican Grill, it was yummy!! The fire pit was so warm. Everything was clean and comfortable, Marsha responded to our messages in a short time and was very kind, will recommend to friends!

Historic 19th Century Cabin/Guest House
Tony was welcoming and accommodating. One reviewer mentioned traffic noise, and while the cabin does sit next to a busy thoroughfare, I didn’t find the noise too disturbing. Overall, worth the price for the convenient location, private parking, and full kitchen. Bonus: Very close to the Swamp Rabbit Trail—we were dropped off at the Ingle’s grocery on Geer Highway and rode to the cabin to from the trail. Approximately 22 miles.
Guest house rentals with a patio

Quaint Cottage Studio in Ashley Forest (Avondale), New Zealand
John and his family offer a cozy place to rest after exploring the nearby neighborhoods by foot and the region by car. A comfy bed, a responsive host, a central location and great local recommendations were highlights.

Bungalow on a 3 acre mini farm
This was an excellent place to stay. It was beautiful. The smell of the air outside was amazing having lived a city for 5 years. Just absolutely gorgeous!

Beautiful Lake Front 1 bedroom Guest House
Rhonda was always willing to help with anything I needed. During Hurricane Helen we lost power and water. Rhonda traveled to North Carolina and picked up a generator to take care of us. Rhonda is willing to go the extra mile to ensure her guests have a great stay in her guests house. I will definitely stay there again.

Cozy 1 Bdrm Cottage~ 1mi to beach~Sleeps4
Very nice and cozy cottage. The bed was very comfortable! We loved that we could bring our dog and that it was fenced in! They were very accommodating and let us stay a little past check out so we could spend more time with our family.

Foothills Favorite
Our stay was great! Check in was super easy and there were super clear instructions for checking in and out. The space itself was spotless and super comfortable. Would stay again!

Driftwood Cottage
Terry made staying at the Driftwood Cottage easy. Everything was clean and comfortable. Nice placce about 25 minutes outside of Charleston. Perfect place for exploring the area. Terry introduced himself and made sure everything was ok. Then I had complete privacy. Perfect host. Would stay at again.

My Happy Place
We loved our stay at the pool house! It had everything we needed and the location was great. I would highly recommend it!

Finished Room over Garage (FROG) on Reedy River
Very clean and all the amenities I needed. Felt very safe and will be back.
Guest house rentals with a washer and dryer

CHS Guest house w/ Pool on Golf Course
The home was neat & clean, conveniently located, private, and quiet. We had so much fun visiting many parts of Charleston with the guest house as our homebase. The home had everything our small family needed for our stay and more! Alicia was a gracious, respectful, and responsive host. She even brought extra supplies to us in case we needed them! We would welcome the opportunity to be a guest with her again.

Groves Carriage House, near Shem Creek
Wonderful, responsive hosts. This above garage unit has everything you need. The neighborhood is very accessible to anywhere you want to go. 5 minutes from Shem Creek. 15 minutes to Sullivan’s Island or Isles of Palms. Roughly 10-15 minutes from Downtown Charleston. The hosts were very helpful with any of my simple needs. I would definitely stay here again.

Leisure Lane-Private Apt on 22 acre Horse Farm
Absolutely amazing place! It’s quiet and a nice getaway from the city, but yet not too far to still see the sights. What you see in the photos is exactly what you get. We were so happy with the apartment, it’s clean, very comfortable and well thought out. A perfect place if you want some quiet after seeing Charleston for the day. Don’t hesitate, this place is perfect! Thanks Megan, you were an incredible host!

The Wren Guest House
Absolutely charming! Would definitely come back and recommend to others! Had everything we needed! Beaufort is a hidden gem and The Wren was perfect! Thank you! 😍 Berkley and Martha Gray

Old Town Bluffton Carriage Apt.
Great location near Bluffton, was in town for a wedding and the rates were way better than in town lodging. Very nice studio with everything we needed.

Lit'l Bit O' Heaven- Rocky Top Lodge
Absolutely loved this little cabin. Very comfortable and would definitely stay again.

Carriage House at 12 Lawrence
We enjoyed our stay at Kristin and Tyler’s bungalow very much! The location was perfect for our nephew’s wedding in Old Town Bluffton, and the bungalow was clean, nicely decorated, and well equipped. We would definitely stay again if in the area, and highly recommend it to others!

Spacious Daniel Island Apartment
We had a wonderful stay at David’s. The space was exactly what we were looking for - clean, quiet, and comfortable. Daniel Island is beautiful, and downtown Charleston and Mount Pleasant are both very accessible by car/Uber. David was very communicative and a great host - we would love to stay here again!
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