House vacation rentals in South Carolina

Find and book unique houses on Airbnb

Top-rated house rentals in South Carolina

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
An outdoor space features a round inground pool with a water feature. Surrounding the pool, lounge chairs and colorful seating areas offer relaxation options. A covered outdoor kitchen is seen in the background against a backdrop of palm trees, enhancing the serene setting.
Home in Myrtle Beach

Southern Comfort

Vacation in the heart of Myrtle Beach! Situated in a quiet neighborhood just .5 miles to Broadway at the Beach and .75 miles to the ocean. Fully renovated home features 4 bedrooms, 4 bathrooms, comfortably sleeps 8 and boasts a brand-new billiards room perfect for evening entertainment. The private, secluded backyard offers an inground pool, outdoor kitchen, TV, and firepit, with plenty of sun and a covered patio for shade. Several golf courses within 10 minutes. Location...Location...Location!

FamilyLocationBeach

4.96 out of 5 average rating, 166 reviews
Top guest favorite
Home in Waterloo

Lake Front/firepit/kayaks/ game room & pool table

Welcome to our sweet lake retreat! Relax with the whole family in our peaceful lakefront home. This is a newer construction home with custom upgrades and sleeps up to 14 people. This is in the BEST location on Lake Greenwood! We are located on the main water and close to Harris landing, Twin rivers, Break on the lake, and the 'sandbar'. Enjoy your morning coffee or evening cocktails on our peaceful porch and watch all the wildlife this lake offers. We would love to have you (NO EVENTS/PARTIES!)

LocationFamilyLaundry

4.99 out of 5 average rating, 178 reviews
Top guest favorite
Home in Pawleys Island

Unique New Remodel Close to Beach and Golf

Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

ValueFamilyNearby

4.95 out of 5 average rating, 201 reviews
Top guest favorite
The image captures a private heated pool beneath a covered patio. Comfortable lounge chairs surround the pool, and an outdoor dining area features a large table with chairs. A shaded umbrella stands above the table, while greenery and a grill are visible, enhancing the outdoor setting.
Home in Hilton Head Island

98 Sandcastle Ct

98 Sandcastle Ct Brand New 6 Bedroom Home near Beach with Pool, Elevator/ (Sleeps Up To 22 Guests ) 20 in beds & 2 in Queen Sofa Sleeper. Over 3200 sq feet, 6 Bedrooms, Heated Pool, Elevator & about .3 miles from the beach = Tons of Fun!!! * 6 Bedrooms * 4 Full Baths * Walking Distance to Ocean. * Heated Private Pool. (Free pool Heat :) * Elevator Available: Free use Adults Only. * Free Parking: 4-6 reg cars/mini vans.. LRG SUV's or LRG Vans = 4 parking spots. Note: 2 = garage 4 =driveway.

ValueLocationHospitality

5.0 out of 5 average rating, 123 reviews
Guest favorite
The outdoor area showcases a tranquil pool surrounded by lush greenery, with comfortable lounge chairs positioned nearby. A pastel sunset provides a serene backdrop, while inflatable pool accessories add a playful touch to the inviting atmosphere.
Home in Simpsonville

Luxury Retreat & Heated Pool Downtown Simpsonville

Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

FamilyValuePets

4.93 out of 5 average rating, 110 reviews
Superhost
A vibrant sunset casts warm hues over the landscape, filling the sky with shades of orange and red. Silhouetted trees form a natural backdrop, while a rustic shelter stands nearby. The open field adds to the expansive view, inviting a sense of tranquility.
Home in Rembert

Pear Tree Farm-pets welcome! Stables/paddocks too!

Relax with the family at this peaceful place with GORGEOUS sunsets. When we say family, we mean pets & horses as well! We have 12 stables, 7 paddocks. Fenced yard & in ground pool. 5 fireplaces & heart pine floors. 3 living/family rooms. Once owned by the DuPont family (yes that DuPont family), the main part of the home is 96 yrs old and has many charming details. The 4 car garage was also the site of building race cars for the DuPonts. Pear Tree Farm offers the best in country quaintness.

FamilyValueLong stay

4.85 out of 5 average rating, 123 reviews
Top guest favorite
The exterior of a two-story house is nestled among tall trees, showcasing a deck with steps leading to the ground. Screened-in porches on both levels provide ample outdoor space and views of the surrounding greenery.
Home in Georgetown

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

ValueLocationDecor

4.98 out of 5 average rating, 190 reviews
Guest favorite
An outdoor game area features a pool table, with a set of colorful balls arranged on the surface. The scene includes a grassy lawn leading to the water, where a sunset illuminates the landscape. Two red chairs and a picnic-style setup are visible nearby.
Home in Prosperity

Sunset Cove-Beautiful Lake views

Your home away from home on Lake Murray! Spacious, modern clean, home with 3 levels of living -3 spacious decks, screen porch, and sunroom all with massive lake views! Plenty to do at Sunset Cove relaxing with family and friends and toys galore! "Wow just wow, best Airbnb ever..Sarah, June 2026. "..clean, beautiful view and so many fun games..Lisa, Oct 2025."Perfect setting for a quiet getaway. The house was amazing, clean, and had all the amenities we were looking for.."Jay, Sept 2025

FamilyValueParking

4.91 out of 5 average rating, 107 reviews
Top guest favorite
A spacious living area features an oversized orange sectional sofa, complemented by a wooden coffee table. A modern kitchen is visible in the background, equipped with stainless steel appliances and white cabinetry. Natural light filters through sheer curtains, creating an inviting atmosphere.
Home in Sumter

3 bd, 2ba, near ShawAFB, Game Rm

Welcome to our newly renovated 3 Bed, 2 Bath, home in Sumter. Our modern decor home has the following: - Master bdrm with King bed/ ensuite bath - Queen beds other rooms - Full equipped kitchen, coffee station - 65", 55", 43" TVs in rooms - Game Room, w/ pool table, table tennis, arcade games - Work area, wifi, 32" monitor, printer, adj height desk - Private backyard, BBQ grill ,gazebo, fire table, games. - Centrally located near Shaw AFB, Tuomey Hospital, food, parks and more

LocationFamilyDecor

4.99 out of 5 average rating, 136 reviews
Guest favorite
Home in Westminster

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

FamilyLocationAccuracy

4.94 out of 5 average rating, 302 reviews
Top guest favorite
A modern kitchen with sleek white cabinetry and granite countertops is highlighted. Four black bar stools are positioned at an island, and stainless steel appliances, including a stove and refrigerator, are visible. Natural light enters through multiple windows, creating a bright and functional space.
Home in West Columbia

Golden Reflections Getaway

Welcome to the Golden Reflection Getaway—a spacious, stylish retreat perfect for families and groups. Enjoy this 2,600+ sq. ft. spacious family area with three luxury themed bedrooms upstairs and extra sleeping options with a full bathroom on the main level. Tucked away in a peaceful neighborhood, just 7 minutes from the vibrant heart of Downtown Columbia and 18 minutes from Fort Jackson. Relax, recharge, and make lasting memories in this thoughtfully designed and comfortable home.

ValueLocationParking

4.99 out of 5 average rating, 163 reviews
Top guest favorite
A tranquil lakeside scene features a circular stone fire pit surrounded by black Adirondack chairs. The vibrant sunset reflects on the calm water, with lush green trees framing the view, creating a serene outdoor space for relaxation.
Home in Camden

Big Water Sunset at Lake it Easy

Escape to Beautiful Lake Wateree for a relaxing weekend away with friends or family. This updated house features 2 bedrooms & 2 bathrooms. Enjoy the cozy vibes of a tastefully decorated space, perfect for unwinding after a day on the lake. Step outside to a serene screened in porch, a fire pit, and stunning big water sunsets that will take your breath away. Whether you're into fishing, kayaking, or simply relaxing by the water, this lakefront house has something for everyone!

ValueLocationCondition

4.95 out of 5 average rating, 123 reviews

Popular amenities for South Carolina house rentals

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