Pet-friendly vacation rentals in South Carolina

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in South Carolina

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite

An outdoor space features a round inground pool with a water feature. Surrounding the pool, lounge chairs and colorful seating areas offer relaxation options. A covered outdoor kitchen is seen in the background against a backdrop of palm trees, enhancing the serene setting.

Home in Myrtle Beach

Southern Comfort

Vacation in the heart of Myrtle Beach! Situated in a quiet neighborhood just .5 miles to Broadway at the Beach and .75 miles to the ocean. Fully renovated home features 4 bedrooms, 4 bathrooms, comfortably sleeps 8 and boasts a brand-new billiards room perfect for evening entertainment. The private, secluded backyard offers an inground pool, outdoor kitchen, TV, and firepit, with plenty of sun and a covered patio for shade. Several golf courses within 10 minutes. Location...Location...Location!

Outdoor spacesPetsDecor

4.96 out of 5 average rating, 167 reviews

Top guest favorite

An airy loft space features a suspended wooden swing, inviting relaxation under the high, timbered ceilings. Natural light streams through large windows, illuminating cozy furnishings including a bed and a dining area with a wooden table. Unique decor elements enhance the overall character.

Guesthouse in Summerville

★Delightful guest house near historic plantations★

Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

Outdoor spacesWalkabilitySleep quality

4.98 out of 5 average rating, 777 reviews

Top guest favorite

The cottage is surrounded by greenery, showcasing a welcoming front porch with white railings. Two planters are placed at the entrance, and a swing is visible on the side. The entrance is accessible from a paved pathway leading to the door.

Cottage in Sumter

Restful Lakeside Cottage -Dogs allowed

This pond-side cottage is a peaceful place to relax & unwind. Sit in the sunroom and enjoy watching the birds & the water or enjoy the front porch rockers where you can listen to the birds & frogs. We are 12 min. from downtown Sumter & 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens, Poinsett State Park & Congaree Nat. Park. It's only 2 hrs to Myrtle Beach or Charleston & 3 hrs to the mtns. While it's conveniently located, this cottage offers a quiet place to relax.

PetsOutdoor spacesEV charging

4.97 out of 5 average rating, 540 reviews

Top guest favorite

A vibrant scene showcases two golden retrievers playing in a shallow stream, surrounded by lush green foliage. Behind them, a cascading waterfall flows over rocky tiers, creating a soothing sound and enhancing the natural beauty of the forested landscape.

Cabin in Oconee County

Secluded Waterfall Cabin.

Romantic, rustic cabin at the base of a 35-foot waterfall, nestled in the middle of 16 secluded acres surrounded by national forest that extends to the Chattooga River. This magical get-away caters to those with an adventurous spirit. Hike from the cabin to additional waterfalls, bike down Turkey Ridge Road to Opossum Creek Trail and the Five Falls or drive two miles to the Chattooga Belle Farm. The Waterfall Cabin is a joy to us all, and we hope you love it as much as we do. No cleaning fee.

Outdoor spacesPetsLong stay

4.99 out of 5 average rating, 401 reviews

Superhost

Cabin in St. Matthews

A relaxing cabin on private pond. Old Bells Secret

Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!

PetsOutdoor spacesCondition

4.76 out of 5 average rating, 206 reviews

Guest favorite

The outdoor area showcases a tranquil pool surrounded by lush greenery, with comfortable lounge chairs positioned nearby. A pastel sunset provides a serene backdrop, while inflatable pool accessories add a playful touch to the inviting atmosphere.

Home in Simpsonville

Luxury Retreat & Heated Pool Downtown Simpsonville

Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

Outdoor spacesPetsLong stay

4.93 out of 5 average rating, 111 reviews

Superhost

A vibrant sunset casts warm hues over the landscape, filling the sky with shades of orange and red. Silhouetted trees form a natural backdrop, while a rustic shelter stands nearby. The open field adds to the expansive view, inviting a sense of tranquility.

Home in Rembert

Pear Tree Farm-pets welcome! Stables/paddocks too!

Relax with the family at this peaceful place with GORGEOUS sunsets. When we say family, we mean pets & horses as well! We have 12 stables, 7 paddocks. Fenced yard & in ground pool. 5 fireplaces & heart pine floors. 3 living/family rooms. Once owned by the DuPont family (yes that DuPont family), the main part of the home is 96 yrs old and has many charming details. The 4 car garage was also the site of building race cars for the DuPonts. Pear Tree Farm offers the best in country quaintness.

PetsOutdoor spacesView

4.85 out of 5 average rating, 123 reviews

Top guest favorite

An aerial view of a spacious two-level brick home is presented, showcasing a large parking area in front with two garage doors visible. Surrounding greenery enhances the setting, while the property is bordered by trees, providing a sense of privacy.

Home in Anderson

Clemson Lake Hartwell Waterfront, Pontoon Rental

Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

WalkabilityOutdoor spacesDecor

4.95 out of 5 average rating, 148 reviews

Top guest favorite

The exterior of a two-story house is nestled among tall trees, showcasing a deck with steps leading to the ground. Screened-in porches on both levels provide ample outdoor space and views of the surrounding greenery.

Home in Georgetown

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

PetsOutdoor spacesCheckout

4.98 out of 5 average rating, 190 reviews

Top guest favorite

A spacious living area features an oversized orange sectional sofa, complemented by a wooden coffee table. A modern kitchen is visible in the background, equipped with stainless steel appliances and white cabinetry. Natural light filters through sheer curtains, creating an inviting atmosphere.

Home in Sumter

3 bd, 2ba, near ShawAFB, Game Rm

Welcome to our newly renovated 3 Bed, 2 Bath, home in Sumter. Our modern decor home has the following: - Master bdrm with King bed/ ensuite bath - Queen beds other rooms - Full equipped kitchen, coffee station - 65", 55", 43" TVs in rooms - Game Room, w/ pool table, table tennis, arcade games - Work area, wifi, 32" monitor, printer, adj height desk - Private backyard, BBQ grill ,gazebo, fire table, games. - Centrally located near Shaw AFB, Tuomey Hospital, food, parks and more

Outdoor spacesPoolTV

4.99 out of 5 average rating, 136 reviews

Top guest favorite

A calm lake reflects soft hues of orange and pink during sunset. A wooden dock extends into the water, surrounded by lush green grass. Trees line the far shore, and a small boat is visible on the horizon, enhancing the serene landscape.

Home in Lake Murray

Anchors Aweigh

Escape to a cozy lakeside cabin just minutes from Dreher Island State Recreation Area. Wake up to peaceful water views and enjoy your morning coffee overlooking the lake. Spend your days swimming, fishing, or cruising the water—bring your boat and take advantage of the private dock. End each evening with breathtaking sunsets right outside your door. Whether you’re seeking relaxation or adventure, this charming retreat offers the perfect getaway to unwind and make unforgettable memories.

WalkabilityPetsCheck-in

5.0 out of 5 average rating, 206 reviews

Top guest favorite

Tiny home in Batesburg-Leesville

Private 75 acre farm with lake

Quiet getaway at Lake Tom-A-Shawna Farm. Fully furnished 2 queen bed, 1 full bath, mini cabin that offers accommodations for traveling professionals, equestrians, and vacationers. This gated private property spans 75 acres, including a 20-acre lake, and features a 4-person cabin with full appliances, granite countertops, high-speed internet, 2 TVs, an electric fireplace, heat/AC, deck. Fishing, shooting, hiking or just relaxing. We offer fresh eggs and meat for purchase.

PetsOutdoor spacesQuiet

4.98 out of 5 average rating, 130 reviews