Hotel vacation rentals in Upstate South Carolina
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in Upstate South Carolina
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina hotel rentals
Family-friendly hotel rentals
Hotel room in Clemson
5.0 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Hotel room in Highlands
4.82 out of 5 average rating, 11 reviewsInn at Mill Creek Suite 4 - Satulah
Boutique hotel in Asheville
4.64 out of 5 average rating, 67 reviewsBrookstone Lodge Boutique Hotel Near City Center
Hotel room in Tryon
4.91 out of 5 average rating, 55 reviewsGreenLife Inn at Mimosa Room 202
Boutique hotel in Chimney Rock
4.83 out of 5 average rating, 12 reviewsKing Bedroom - No Cleaning Fees & Free Breakfast!
Hotel in Fletcher
4.86 out of 5 average rating, 56 reviewsCabin 400 sq all for you.
Hotel in Hendersonville
4.67 out of 5 average rating, 6 reviewsLarge King Room, Breakfast & WIFI included
Nature lodge in Lake Junaluska
4.7 out of 5 average rating, 231 reviewsThe Providence Lodge and Gallery
Hotel rentals with a pool
Hotel room in Clarkesville
Lovely for family - 2BD/2BA
Hotel room in Lake Lure
4.57 out of 5 average rating, 7 reviewsChimney Rock Inn - Room 7
Hotel in Greenville
5.0 out of 5 average rating, 6 reviewsWingate (K)
Nature lodge in Mill Spring
4.82 out of 5 average rating, 11 reviewsBright's Creek Lodge - Double Queen w/ Balcony
Resort in Flat Rock
4.75 out of 5 average rating, 4 reviewsMill House Lodge - Studio King
Resort in Bryson City
5.0 out of 5 average rating, 3 reviewsLodge 06 Pool View
Nature lodge in Bryson City
5.0 out of 5 average rating, 3 reviewsQuaint Airbnb village with gorgeous views!
Resort in Lake Lure
4.69 out of 5 average rating, 16 reviewsFairfield Mountains Resort - 2 Bedroom Deluxe
Hotel rentals with a patio
Hotel in Washington
4.83 out of 5 average rating, 12 reviewsThe Fitzpatrick Hotel Washington - Deluxe Rooms
Room in Irmo
5.0 out of 5 average rating, 10 reviewsRelax in beach themed room.
Hotel in Whittier
4.95 out of 5 average rating, 40 reviewsThe Blue Ridge Suite at the Lodge at Smoky Cove
Boutique hotel in Hendersonville
4.8 out of 5 average rating, 10 reviewsDouble Queen Rm: Near DT Hendo & Flat Rock
Hotel in Lake Lure
1 Bedroom Deluxe @ Wyndham Fairfield Mountains
Boutique hotel in Highlands
4.64 out of 5 average rating, 11 reviewsGranite King Room - 1920's Mid Century Lodge
Hotel in Maggie Valley
5.0 out of 5 average rating, 13 reviewsThe Azalea Suite at the Dogwood
Boutique hotel in Asheville
5.0 out of 5 average rating, 7 reviewsBiltmore Hideaway Villa
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- Rentals with a washer and dryer Upstate South Carolina
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