
Hotels in Upstate South Carolina
Find and book unique hotels on Airbnb
Top-rated hotels in Upstate South Carolina
Guests agree: these hotels are highly rated for location, cleanliness, and more.

Log Suite at our Boutique Bed & Brewery
Our Two-Story log suites are the perfect basecamp for couples and families alike. They offer two bedrooms with two spacious bathrooms, along with a small kitchen, equipped with induction cook top and refrigerator. Great for extended weekends or a quick trip to enjoy the beauty of Cashiers, North Carolina. Be sure to take a quick hike over to our on-site brewery, Whiteside Brewing Co., and enjoy the great food and drink selection they have to offer. This suite is sure to cure what “ales” you! ;)

Outpost Inn Highlands
The Petite is our 170 SF Queen hotel room with all of the bells and whistles of larger rooms but in a cozier footprint- luxury Queen mattress, Italian linens, vintage Appalachian textiles, Pendleton Blankets, coffeemaker, minibar with NC goodies, minifridge, luxury bathroom with robe, luxury toiletries and amazing walk in shower with the best water pressure. Please note this Room has since been painted Hague Blue by Farrow and Ball (pics on the way!). Outside your door is our newest firepit!

Boutique Hotel: The Princess Bride Suite
The princess bride quarter is your romantic honeymoon suite. This natural light infused room is a large master suite overlooking the back gardens and ceremony site for weddings. A truly romantic room that evokes a modern Parisian style room. 300 square feet of luxury with spa-like walk-in shower. Slip into our monogram Boutique Auberge robe and luxuriate in an intoxicating scent from our keepsake soap made exclusively for Boutique Auberge. Hot breakfast included upon request.

Asheville Escape | Free Parking & Pet-Friendly
Experience Asheville’s charm at Holiday Inn Asheville East-Blue Ridge Parkway, a pet-friendly mountain lodge hotel perfectly situated near Biltmore Estate and the Blue Ridge Parkway. Enjoy an on-site dining at Woodfire Grille & Bar and modern amenities like free WiFi, EV chargers, and a fitness center. Explore attractions, hiking trails, and scenic views, all just minutes away. Perfect for families, pets, and tour groups, offering comfort and convenience in a prime location.

King Room at Bridge Creek Inn
Settle into comfort in our Standard King Room at Bridge Creek Inn—perfect for solo travelers or couples. This stylish room features a plush king bed, smart TV, mini-fridge, and a modern bathroom with a walk-in shower. Natural light fills the space, creating a warm and relaxing atmosphere. Enjoy high-speed Wi-Fi and a cozy layout ideal for work or rest. Don’t miss Vandiver, our onsite restaurant and bar, serving up Southern-inspired cuisine and craft cocktails daily.

Swayze Suite at Lake Lure Inn
Experience vintage elegance and modern comfort in the Swayze Suite at The Lake Lure Inn and Spa. This luxurious retreat features a king-sized bed, spa-inspired bathroom, and a cozy living area with old Hollywood charm. Guests enjoy access to the inn’s pool, on-site dining, and spa. Explore Lake Lure's scenic beauty and iconic "Dirty Dancing" locations. Perfect for romance or relaxation, this suite offers an unforgettable getaway. Book now for timeless memories!

King room with City View at Kimpton!
Stay steps from Asheville’s buzzing breweries, indie art galleries, and live music at Kimpton Hotel Arras. Your room blends boutique flair with luxe linens, spa-inspired bathrooms, and city or Blue Ridge Mountain views. Grab a cocktail at the lobby bar, hop on a complimentary bike to explore downtown, or soak up Asheville’s creative soul with your pup in tow. Warm Southern vibes, walkable adventures, and boutique perks make this the ultimate Asheville escape.

Cozy mountain lodge
Small hotel near South Mountain State Park, perfect for hikers, explorers, and anyone seeking a peaceful nature retreat. We’re in the process of reopening, with some tidying up and repairs still underway. The pool isn’t open yet, and the exterior is being organized, but if you don’t mind that, this is a quiet, secluded, and affordable getaway. We’re only hosting a limited number of guests right now, and we’d love to have you stay with us!

Pet Friendly, Outdoor Grills & Gym Access
Make yourself at home at TownePlace Suites Asheville Downtown, where comfort meets convenience. Nestled just minutes from the stunning Carolina National Parks and right in the heart of Asheville’s vibrant scene, our hotel places you steps from renowned restaurants, local breweries, and cultural hotspots. Enjoy inviting outdoor spaces with a fireplace and grills—perfect for relaxing after a day of adventure.

Mountain views @ Boutique Hotel
1936 Georgian-Revival, turned Coffee + Cocktail Bar, Housing NC's Smallest Boutique Hotel. This moody, color-drenched studio offers a private balcony with mountain views. Please note: the coffee/bar is open to the public and there is potential for noise. The bar closes at 9pm on weekdays and 10pm on Fri/Sat. Hotel is suggested adults only (21+)

The Abernathy
The Abernathy is located one block from The Rock and offers guests large rooms with 445 sq. ft. to stretch out and enjoy their stay in Clemson. Bicycles are available for guests to take on a leisurely pedal through Clemson's campus at their own pace. There is also an on-site bar to enjoy after a long day of exploring.

Kanuga Lake Inn - King Shared Balcony
Traditional hotel accommodation that includes a king bed, private bathroom and air conditioning/heating. These rooms feature a shared balcony with the adjacent room that overlooks into a courtyard area or a parking lot. Our hotel rooms do not have a view of the lake. Please note there is not a TV in the room.
Popular amenities for Upstate South Carolina hotels
Family-friendly hotels

Cozy Hotel Room for 2 on Main St. in Hiawassee!

Pet-Friendly 1BR Suite Near Rock Hill Galleria

Minutes to Charlotte + Pool. Bar & Free Parking

Warm Southern Hospitality | Indoor Pool

2 Queen Room

Ramsey Hotel & Convention Center | Two Queens Room

Mount Mitchell Eco Retreat - Winter Star Lodge

Indoor Swimming Pool, Pets Allowed! Rare Find!
Hotels with a pool

Convenient Unit | Prime Location | Free Breakfast

Smoky Mountain Resort | 1BR + Water Park Access #2

Convenient Stay in Athens! Free Breakfast, Pool!

Near BMW Zentrum with Free Breakfast, Pool & Gym

Lodge 11 Deluxe Mountain View

Single Unit Mountain Cabin Resort Experience

Comfortable stay near USC, Downtown & Airport

GLō Hotel Asheville-Blue Ridge Parkway
Hotels with a patio

1‑Bedroom Retreat at Fairfield Sapphire Valley

Lakefront Water Studio w/ Porch #11(Light Blue)

Resort at Fairfield Sapphire Valley 1 Bedroom Unit

Monte Vista 1937 Double Queen

The Lost Compass - Suite #2 - Cozy Cabin Retreat

2BD/2BA Condo Near Biltmore Estate and Downtown

Gatlinburg Family Getaway

Smoky Mountain Resort w/ Water Park Access 2 rooms
Destinations to explore
- Western North Carolina Vacation rentals
- Atlanta Vacation rentals
- Nashville Vacation rentals
- Myrtle Beach Vacation rentals
- Charleston Vacation rentals
- Gatlinburg Vacation rentals
- Charlotte Vacation rentals
- Hilton Head Island Vacation rentals
- Savannah Vacation rentals
- Cape Fear River Vacation rentals
- North Myrtle Beach Vacation rentals
- Pigeon Forge Vacation rentals
- Treehouse rentals Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Rentals with a washer and dryer Upstate South Carolina
- Villa rentals Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Farmstay rentals Upstate South Carolina
- RV rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Rentals with an accessible height toilet Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- House rentals Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Barn rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Tent rentals Upstate South Carolina
- Resort rentals Upstate South Carolina
- Boutique hotels Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Rentals with a home theater Upstate South Carolina
- Condo rentals Upstate South Carolina
- Guesthouse rentals Upstate South Carolina
- Campsite rentals Upstate South Carolina
- Rentals with a fire pit Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Vacation home rentals Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Hotel rooms South Carolina
- Hotel rooms United States
- Blue Ridge Parkway
- Clemson University
- The North Carolina Arboretum
- Chimney Rock State Park
- Gorges State Park
- Lake Lure Beach and Water Park
- Table Rock State Park
- Tryon International Equestrian Center
- Jump Off Rock
- Ski Sapphire Valley
- Saint Paul Mountain Vineyards
- Burntshirt Vineyards
- Bon Secours Wellness Arena
- Fluor Field at the West End
- DuPont State Forest
- Devils Fork State Park
- Looking Glass Falls
- Carl Sandburg Home National Historic Site
- Overmountain Vineyards
- Peace Center
- Fred W Symmes Chapel
- Jones Gap State Park
- Falls Park On The Reedy
- Whitewater Falls
- Things to do Upstate South Carolina
- Things to do South Carolina
- Tours South Carolina
- Sports activities South Carolina
- Food and drink South Carolina
- Entertainment South Carolina
- Nature and outdoors South Carolina
- Sightseeing South Carolina
- Art and culture South Carolina
- Things to do United States
- Sightseeing United States
- Tours United States
- Food and drink United States
- Entertainment United States
- Sports activities United States
- Art and culture United States
- Nature and outdoors United States
- Wellness United States





