Vacation home rentals in Upstate South Carolina

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Top-rated vacation home rentals in Upstate South Carolina

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious exterior view of the building is shown, featuring a distinctive pink facade and a textured roof. A wooden staircase leads to an upper deck, while two chairs are positioned on a gravel area beside the entrance. Lush greenery surrounds the structure.

Vacation home in Pisgah Forest

4.99 out of 5 average rating, 86 reviews

Wake surrounded by views of the beautiful Blue Ridge Mountains in this lovely 1 bedroom vacation home.

Forget your worries in this spacious and serene space with indoor fireplace,full kitchen,laundry room,air, covered parking,large deck and outdoor fire pit/dining area. Minutes from hiking,biking,fishing,golf, 200+ waterfalls, dining, downtown Brevard, shopping,local breweries. Located between Pisgah National and DuPont State Forests. 30 minutes from Asheville airport and 20 minutes from historic Hendersonville. Brevard Music Center, Cradle of Forestry,Flat Rock Playhouse, Biltmore House nearby

Superhost

Vacation home in Anderson

4.94 out of 5 average rating, 18 reviews

Clemson/Anderson Lake Hartwell

Beautiful lake house for family fun in wonderful neighborhood, 15 minutes from Clemson. 2 kings, 2 queens , 2 doubles, crib, pack&play, Roll out toddler cots. Well equipped kitchen. Gas logs in living room. Wonderful deck with outdoor table and plenty of chairs for relaxing and enjoying views. Huge dining table seats 8 to 10. Antique bar in den. Large den has sectional sofa and 4 LazyBoy recliners Fire pit , grill , hot tub. Deck has nice view of lake. Dock has 2 double kayaks Enjoy!

Guest favorite

Vacation home in Greenville

4.92 out of 5 average rating, 157 reviews

City Dream Nostalgic 2BR 2BA Walk the Heart of GVL

Ideal for business travelers-family-friends. Enjoy a city getaway from a prime location. Walk, trolley or bring bikes. Our West End gem is 5 min walk to bcycle/trolley @Fluor Field.10 min walk to Falls.Uber friendly.See shops-art galleries-museums-tours-eateries-breweries-outdoor activities.Newly remodeled spacious historic bldg w 10 ceilings, wood floors & new baths. 1300 sq.ft entire 1st floor. 1 King &1 Queen bed.Large private patio, kitchen/living/dining. Game room, records & more. Park FREE

Guest favorite

A covered porch offers a peaceful view of the surrounding mountains and greenery. Two rocking chairs sit beside a small table, while an American flag gently flutters in the breeze. The light wooden floor enhances the inviting atmosphere of the outdoor space.

Vacation home in Waynesville

4.96 out of 5 average rating, 24 reviews

Mountain Retreat - All New - Intown Waynesville NC

Your family will be close to everything when you stay at this centrally-located home in Waynesville, NC with Hot Tub, Fire pit and Game Room. This Mountain Retreat is the best of both worlds - amazing mountain views with easy walkability right in town. In the heart of the Smoky Mountains and Blue Ridge Parkway. Just 35 minutes to Asheville and Biltmore House. Closeby Harrah's Casino, Maggie Valley & Cataloochee Ski Area & Lake Junaluska. Enjoy white water rafting, skiing, hiking, Ziplining.

Superhost

Vacation home in Waynesville

4.78 out of 5 average rating, 23 reviews

The Maxwell House Inn - A Mountain Retreat!

Mountain retreat! With a HOT TUB, Sleeps 5, close to town between the Smokey Mountains and the Blue Ridge Mountains. This bright, spacious apartment has space for up to 5 people and consists of two bedrooms both with queen beds and a game room with a twin bed with a trundle. Two flat screen TV’s, two electric fireplaces, a great room with comfortable sofa and chair w/ ottoman, cable and WIFI . A, efficiency kitchen with a fridge and stove. Plus a additional full size fridge in the game room.

Guest favorite

A large dock extends over calm waters, with a covered area providing shade. Several water activities are visible, including a paddleboard, a kayak, and floating mats. Surrounding trees offer a natural border, enhancing the serene lakefront setting.

Vacation home in Fair Play

5 out of 5 average rating, 22 reviews

Spend your vacation lakefront

*No cleaning fee. Peaceful lakefront home with gentle slope toward the water with a large dock for your boat, sunbathing or morning coffee. The completely renovated 2 bedroom/1 bath home has an outdoor covered kitchen perfect for family meals. The 20x40 ft deck off the kitchen provides plenty of space for entertaining, playing or an outdoor movie! We have several kayaks, paddleboard, water tubes, carpet islands and games to build memories to last a lifetime. 4 night minimum May-August.

Top guest favorite

An outdoor seating area is depicted with comfortable chairs arranged around a decorative area rug. Potted plants and greenery surround the space, providing a natural and serene ambiance. A wooden railing outlines the area, enhancing the connection to the surrounding landscape.

Vacation home in Tryon

5 out of 5 average rating, 100 reviews

Sandy Plains Fountain Home | King Bed | 3 MI TIEC

2 Bedrooms - 1 king bed & 1 queen, 1 bath Efficiency kitchen ( we are testing an additional space that we have recently added as another bedroom as an extra bonus room ) there will be an extra 100$ added separately by the host for use of 3rd bedroom- 2 night minimum Detached Laundry facility on property where nature surrounds you with additional outside seating & dining . Peaceful and centrally-located 3 miles from Tryon International Equestrian Center TIEC & local wineries .

Top guest favorite

Vacation home in Anderson

4.99 out of 5 average rating, 100 reviews

Lake House and Dock Upscale and Immaculate

Our immaculate 2020 built water-themed home is a luxury furnished lakefront 1.1 acre property on Lake Hartwell with a large boat dock. Our house enjoys amazing lake views and is perfect for the tournament fisherman, the boating enthusiast, golfers, families and those just needing to relax. We are down the street from Stonecreek Cove Golf Course in a countryside atmosphere and are comfortably close to the renowned Green Pond Landing, host to many national fishing tournaments.

Top guest favorite

A spacious living area features high wooden ceilings and warm, natural light. Cozy seating arrangements are highlighted by a stone fireplace and a large window overlooking the outdoors. Decorative accents include plants, artwork, and a vintage lighting fixture that add character.

Vacation home in Highlands

5 out of 5 average rating, 38 reviews

Broadview A Highlands Mountain Top Retreat

Relax with the whole family while taking in the sounds of nature from atop, at Broadview. Known for its beautiful sweeping views of the breathtaking Blue Valley you’ll have a front row seat to enjoy the magic of nature as morning sunrises and evening sunsets surprise you daily. Broadview has been re-born into a chef’s dream retreat. Perfect for entertaining family and friends inside or outside on the sprawling screened porch or the open terrace overlooking Blue Valley.

Superhost

A rustic cabin is framed by lush greenery, featuring a large porch supported by wooden beams. A stone pathway leads to a gentle stream adorned with smooth rocks. The serene setting evokes a sense of tranquility amidst nature.

Vacation home in Lake Lure

4.84 out of 5 average rating, 25 reviews

Trout Stream Resort Home & Guest Cabin/Pavilion

Waterfall Property located w/i Rumbling Bald Resort on 1.5+ acres w/ stream, waterfalls & swimming hole. Perfect location to get away from it all. Main home sleeps 15. Cabin/Pavilion w/ covered area + sleeping/living area. Heat/AC/fans/Three fireplaces ,and fire pit throughout. Porches, decks & patios provide areas to gather. Enjoy the sound of waterfalls, roast marshmallows or play games by a fire, resort's amenities, upgraded wifi. Additional Homes available.

Guest favorite

The house is surrounded by lush greenery and features multiple patio levels. A stone fire pit with seating is situated on the lawn, creating an inviting space for gatherings. The expansive deck extends from the upper floor, providing views of the serene backyard.

Vacation home in Fair Play

4.96 out of 5 average rating, 45 reviews

Lakefront Hartwell Home w/NEW Dock + NEW Fire Pit

This 5 bedroom/3.5 bath house sleeps 14 and is perfect if you enjoy all of the amenities of a resort + the perks of a quiet, private home. Resort-style amenities include: a new covered dock with two boat slips, kayak, paddleboards, stone fire pit, NEW Hot Tub, stacked porches with ample seating and dining spaces, two indoor fireplaces, a full kitchen and a kichenette, comfortable beds, a serene gazebo - all nestled in the natural beauty of Lake Hartwell.

Top guest favorite

Vacation home in Bryson City

4.96 out of 5 average rating, 74 reviews

Nantahala River 2BR - Bear Cave Boat Parade

Closest rental to the Nantahala Outdoor Center! 1.5 miles upriver. Trains daily. NO SMOKING, NO PETS, no exceptions. Service animal excepted. Read CANCELLATION POLICY before booking and house rules before booking. NO TRASH SERVICE in area, guest must remove when checking out. NOT SAFE for small children due to powerful water just off deck. WI-FI provided. CELL Coverage: Verizon = Excellent. T Mobile = No Coverage. ATT Some Coverage Outdoors.

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What guests are saying

Eagle's Nest

4.46 out of 5 average rating, 50 reviews1 month ago

I loved it.. I did record stepping in and out and one thing we noticed was just the fridge look like if someone wasted something in the back of the fridge so it was stilll dirty from that on the top rack but other than that everything was beautiful. We also had an issue with 3 wasps in the second bedroom, but we were also located in the mountain so understand that bugs could have been an issue. The place was lovely. The location scenery was spot on and the atmosphere is very peaceful and relaxing. The location is about an hour and 30 mins from everything we wanted to do which was great distance. But if you want to be close in town to things then this wouldn’t be for you.

Vacation home in Bryson City