
Guesthouse vacation rentals in Upstate South Carolina
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Top-rated guesthouse rentals in Upstate South Carolina
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
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Popular amenities for Upstate South Carolina guesthouse rentals
Family-friendly guest house rentals

Cozy studio loft in the Blue Ridge Mountains
Great place to see when visiting Pisgah National Forest attractions and/or Great Smoky Mountains. Comfortable, quiet, and clean :)

Great 1 BR house in Normaltown
Lovely little home with lovely flowers and artistic touches. Perfect quiet location while visiting my son at UGA. Juana was very accommodating when I made a last minute reservation, and had everything ready for us when we arrived.

Home on the farm
Awesome little getaway. From fishing to riding the trails on the property l and splashing around in the pool. It was peaceful. Kids had an awesome time.

Loft in the Countryside
Perfect for our quick weekend in Asheville with the pup!

Historic Jockey Cottage, TIEC 20 mins, Tryon 5
My husband and I stayed a week over Christmas to visit family. Terry and Bill met us when we arrived and were super friendly and showed us around, met our dog, and gave us the history of the cottage. The cottage was very cozy and exactly what we needed! Gorgeous scenery and was fun to see the horses every morning. We will be back!

Rocking chair porch in Mills River! Relax
Great hosts , beautiful unique little home with everything that was needed! Highly recommended if you want a quiet place to relax!

Mountain Edge Loft
Beautiful land and home, cute dogs and chickens, the bread was delicious and i definitely recommend California's Mexican Grill, it was yummy!! The fire pit was so warm. Everything was clean and comfortable, Marsha responded to our messages in a short time and was very kind, will recommend to friends!

Betty's Creek Loft in Rabun Gap.
We thoroughly enjoyed Matthew and Beverly’s Loft. It was perfect! Very peaceful with magnificent views! This was our first AirBNB stay and we couldn’t have been more pleased. We plan to come back to this loft again.
Guest house rentals with a patio

The Lodge at Pythian Park
We loved the peaceful stream and the quiet location. Ginny and Terry are wonderful hosts, along with their well-mannered, beautiful dogs. It is tucked away 10 minutes from everything on a beautiful piece of property. The room is very clean and new. Every detail and need is noticed. Ginny even had ice made for us before we got there! The bed is soooo comfortable and the sheets were super soft. Everything was perfect!

Classic City Cottage
Great place to stay - met all of our needs and then some. Perfect for a night before the Georgia G Day scrimmage game. Host was super helpful and responsive.

Beautiful Lake Front 1 bedroom Guest House
Rhonda was always willing to help with anything I needed. During Hurricane Helen we lost power and water. Rhonda traveled to North Carolina and picked up a generator to take care of us. Rhonda is willing to go the extra mile to ensure her guests have a great stay in her guests house. I will definitely stay there again.

Starswept Studio–Walk to Brewery, Near BRP & GSMNP
Great location, friendly host, clean and very well appointed private space…this is what all other Air BnBs should aspire to!

Tranquil 2BR Guest House on Pond by Furman
Peaceful surroundings with pond and patio. Great location. Close to shopping, swamp rabbit trail, parks, and mountains. Very clean and nicely decorated. Very responsive host. Hope to stay again.

Foothills Favorite
Our stay was great! Check in was super easy and there were super clear instructions for checking in and out. The space itself was spotless and super comfortable. Would stay again!

Cozy Downtown GVL Studio
This is a great place to stay in Greenville! It was conveniently close to downtown which we found to be perfect for our stay! Jonathan responded quickly to our messages and was a great host!

Finished Room over Garage (FROG) on Reedy River
It was so beautiful and peaceful A beautiful view to drink your morning Coffee So quiet no traffic sounds Very very clean Couch and bed very comfortable I really enjoyed the trail great walk I loved everything Bret was a great host Always quick to answer questions Checked to see if we needed anything So friendly I would stay again It was such a great stay😄😄😄😄😄😊
Guest house rentals with a washer and dryer

Explore the Woods from a Quiet Apartment near Sierra Nevada
A beautiful, quaint little spot! Perfect for my brother and I while we were attending Arborfest in Fletcher this weekend!

Wolf Lake Escape - lake & mountain retreat
Wolf Lake Escape is a great little remote spot right on the lake. Kathleen is an excellent host and Tilley the dog is a friendly co-host! The apartment is private and the views of the lake from just outside the door are beautiful. Thanks Kathleen, we’ll be back!

Gallery Carriage House DT Watkinsville w EV
2nd time there, location is close to art, shopping, walking trails and good food

Spring in the Smoky Mountains,Canton (AVL)-amazing
Stayed at Gregg & Lynn’s for one night on a road trip. They were super-responsive, and the place had everything I needed—hot shower, laundry, and comfy bed. The views were nice and it was very quiet and private. Be aware that there are many stairs leading up to the front door.

Camper at Hickory Lodge and Guesthouse
We had an enjoyable stay in the camper! Our first time to experience staying in a camper. It was a fun experience.

Lit'l Bit O' Heaven- Rocky Top Lodge
Absolutely loved this little cabin. Very comfortable and would definitely stay again.

Cabin in the Pines
It was a great place to stay. I would highly recommend this cute little cabin. Thanks, Pam

Five Points Dawg Suite
This guest house was just what I needed. I stayed for a total of 9 nights. The home was clean, private and I felt very safe. If I had anything negative to say it would only be that the guest house needed an iron. Other than that absolutely no complaints.
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