Family-friendly vacation rentals in Upstate South Carolina

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Upstate South Carolina

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite

The entrance features large, rustic double doors opening to reveal a stylishly decorated bedroom. A crystal chandelier hangs above a beautifully crafted bed with an intricate headboard. Two decorative topiary plants frame the doorway, adding a touch of greenery to the warm wooden floor.

Treehouse in Waterloo

#1 most loved AirBnB in SC! *Old Soul Treehouse*

The Old Soul Treehouse is a fabulous destination for couples looking to have a unique getaway! This is a waterfront treehouse on Lake Greenwood with a private dock, heat/AC, hot tub, king size bed, & a fully equipped kitchen & bathroom. Take a dip in the lake during the day or at night enjoy a soak in the hot tub on the peaceful porch under the stars. Book with us and you will soon be enjoying luxury by the water during this intimate experience with the one you love. We would love to have you!

4.99 out of 5 average rating, 257 reviews

Top guest favorite

A rustic cottage is situated on a grassy area, bordered by a fence. The structure features a wooden exterior, a metal roof, and a welcoming porch with a view. Nearby, a horse grazes peacefully, adding a serene touch to the natural surroundings.

Tiny home in Donalds

The Cottage at Flourish Farm - 6 mins to Erskine

Enjoy the farm experience or a quiet getaway in our cozy cottage! Designed for maximum coziness at only 192 sq ft, it's the perfect place to get away. While designed for two, we can provide an additional twin mattress. The kitchenette includes a compact fridge/freezer, microwave, and coffee maker. The queen size bed next to the fireplace is the perfect place to watch a movie or read a book, or enjoy coffee and sunsets from the rocking chairs on the wraparound porch. We hope to see you soon!

4.99 out of 5 average rating, 216 reviews

Top guest favorite

A treehouse surrounded by trees glows gently with warm lights in the evening. Two Adirondack chairs are positioned around a fire pit, with a small table nearby. The forest setting offers a calm and inviting atmosphere for outdoor relaxation.

Treehouse in Mountain Rest

THE BELLA LUNA Romantic Treehouse - Outdoor Shower

This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

5.0 out of 5 average rating, 490 reviews

Guest favorite

Dome in Salem

Farm Geodome Near Lake Jocassee, Hot Tub, Zip Line

Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

4.88 out of 5 average rating, 400 reviews

Guest favorite

The outdoor area showcases a tranquil pool surrounded by lush greenery, with comfortable lounge chairs positioned nearby. A pastel sunset provides a serene backdrop, while inflatable pool accessories add a playful touch to the inviting atmosphere.

Home in Simpsonville

Luxury Retreat & Heated Pool Downtown Simpsonville

Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

4.93 out of 5 average rating, 107 reviews

Top guest favorite

An aerial view of a spacious two-level brick home is presented, showcasing a large parking area in front with two garage doors visible. Surrounding greenery enhances the setting, while the property is bordered by trees, providing a sense of privacy.

Home in Anderson

Clemson Lake Hartwell Waterfront, Pontoon Rental

Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

4.94 out of 5 average rating, 145 reviews

Top guest favorite

Home in Lake Toxaway

Cabin I Private hiking trails | Hot Tub I Sauna

Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

4.99 out of 5 average rating, 378 reviews

Top guest favorite

Cabin in Tamassee

A Lakefront Tiny Cabin • Hot Tub • Kayaks • Canoe

Wake up to peaceful lake views, sip coffee on the porch, and spend the day kayaking or swimming from your private dock at Whitewater Cabin. This lakefront cabin is tucked away on a private Lake in the South Carolina mountains, minutes from Lake Jocassee, and sleeps 6. It’s the perfect getaway for couples, families, or friends looking to escape into nature. After a day exploring waterfalls, hiking, or boating on Lake Jocassee, come back and unwind in the hot tub overlooking the water.

4.97 out of 5 average rating, 185 reviews

Top guest favorite

A cozy campsite is illuminated by string lights in the evening. A vintage camper is situated under a wooden canopy, with a stone path leading to a fire pit surrounded by two wooden chairs. Nearby, a small table provides an additional seating area.

Camper/RV in Woodruff

70's Nostalgia

Go back to a simpler time in this totally restored 1969 Concord Traveler at Kingfish Farms. Located just a mile and a half from the quaint town of Woodruff, SC. and a little over 2 miles from I-26. Our 20 acre farm gives you plenty of room to enjoy the outdoors and get back to nature. Relax and rejuvenate in our traditional Finnish sauna and outdoor shower. Take a walk through our wooded trail and visit the goats, pigs and chickens. Stop by our farm store and u-pick flower garden.

4.97 out of 5 average rating, 235 reviews

Top guest favorite

The image showcases a charming early 1900s barn with a modern metal roof, set against a backdrop of green hills and trees. Sunlight filters through the leaves, illuminating the open pasture nearby. A sense of tranquility is portrayed in this rural setting.

Barn in Easley

The Hayloft: 20+ mins to Downtown Greenville

Enjoy a unique getaway in our early 1900s barn, re-imagined to wow you with a modern design of this traditional setting. Start your morning in our 900 sq ft Hayloft with farm fresh eggs from our free-range hens, watch our goats graze in the pasture as you take in the beautiful sunsets from the covered deck, or enjoy a relaxing bath in our soaking tub. -10 mins to Downtown Easley -20-40 mins to: *Table Rock State Park *Lakes Keowee/Jocassee *Clemson *Downtown Greenville

5.0 out of 5 average rating, 120 reviews

Top guest favorite

The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.

Home in Greenville

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

4.99 out of 5 average rating, 275 reviews

Top guest favorite

The living area features wood-paneled walls complemented by a ceiling fan. A dark leather couch and a matching chair surround a wooden coffee table. Decor includes mounted antlers and a turkey, with plaid curtains framing the windows. A door leads outside, and a television is positioned nearby.

Cabin in Donalds

Cabin in the woods

aprx. 4 miles to Erskine college, Good for couples, solo adventurers, business travelers, and furry friends (pets).11 miles from Abbeville~Birth of the confederacy. aprox. 60 miles to Augusta Ga the masters golf tour. aprx. 40 miles to Clemson U. Available walking trails down to stream and around the farm. Fishing dock . Plenty of parking. The Diamond Hill Mine in Abbeville is about 17 miles from here.

4.98 out of 5 average rating, 482 reviews