
House vacation rentals in Panama City
Find and book unique houses on Airbnb
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City house rentals
House rentals with a pool

Luxury Home with Pool in the Best Neighborhood

Luxurious beachfront home in Veracruz

A beautiful apartment with a swimming pool, BBQ area, and gym

Beautiful house in Brisas del Golf

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

House of the waterfalls

Airbnb - Vacation

Your country house, Menus de la Montaña, awaits you.
Weekly house rentals

Family-Friendly Panama Canal Home with Fenced Yard

Modern and minimalist Altos de Cerro Azul

Country house in Altos de Cerro Azul

Specious house that can accommodate up to seven

A nice house equipped for rest or home office

La Colina, Altos de Cerro Azul

Family House | 3 floors | BBQ | 20 Pax | Parking

Welcome to Zola Sierra! Your Escape Into Nature.
Private house rentals

Bruno's House

Cozy house with a garden

Villa on the Beach, entire house

The Bird's Nest - Cerro Azul

Illuminated HOUSE _312m2 + pool + garden

Gorgeous Renovated Canal Home - Med or Longterm

Cozy and spacious house

Carmen's House
Quick stats about house rentals in Panama City
Total rentals
450 properties
Nightly prices starting at
ﺩ.ﺇ37 before taxes and fees
Total number of reviews
6.8K reviews
Family-friendly rentals
170 properties are a good fit for families
Pet-friendly rentals
140 properties allow pets
Rentals with a pool
90 properties have a pool
Destinations to explore
- Cartagena Vacation rentals
- San Andrés Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Uvita Vacation rentals
- Boquete Vacation rentals
- Coveñas Vacation rentals
- Playa Blanca Vacation rentals
- Bahía Ballena Vacation rentals
- Limón Vacation rentals
- Ancón Vacation rentals
- Playa Venao Vacation rentals
- Cahuita Vacation rentals
- Rentals with outdoor seating Panama City
- Rentals with a sauna Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Rentals with a home theater Panama City
- Rentals with an EV charger Panama City
- Waterfront rentals Panama City
- Condo rentals Panama City
- Hostel rentals Panama City
- Smoking-friendly rentals Panama City
- Loft rentals Panama City
- Rentals with a washer and dryer Panama City
- Pet-friendly rentals Panama City
- Cabin rentals Panama City
- Serviced apartment rentals Panama City
- Rentals with pools Panama City
- Fitness-friendly rentals Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Rentals with an accessible height bed Panama City
- Villa rentals Panama City
- Townhouse rentals Panama City
- Rentals with lake access Panama City
- Rentals with a patio Panama City
- Rentals with a fire pit Panama City
- Rentals with a hot tub Panama City
- Hotel rentals Panama City
- Guesthouse rentals Panama City
- Rentals with beach access Panama City
- Rentals with breakfast Panama City
- House rentals Panamá Province
- House rentals Panama
- Things to do Panama City
- Art and culture Panama City
- Sports activities Panama City
- Tours Panama City
- Sightseeing Panama City
- Food and drink Panama City
- Nature and outdoors Panama City
- Things to do Panamá Province
- Tours Panamá Province
- Nature and outdoors Panamá Province
- Art and culture Panamá Province
- Food and drink Panamá Province
- Sightseeing Panamá Province
- Things to do Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Sports activities Panama
- Tours Panama
- Entertainment Panama
- Art and culture Panama
- Food and drink Panama