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Loft vacation rentals in Panama City

Find and book unique loft rentals on Airbnb

Top-rated loft rentals in Panama City

Guests agree: these loft rentals are highly rated for location, cleanliness, and more.

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Superhost
Loft in Panamá
4.83 out of 5 average rating, 108 reviews

Romantic Loft Casco Viejo • Plaza Views & Top Spot

Mi casita de Azúcar is a beautiful renovated 1 bedroom loft with plenty of Romance! With everything new, it is located in the Heart of the UNESCO World Heritage Old Town. In front of the Great Plaza Mayor, BEST LOCATION in the area. Very close to restaurants, shops and bars. Shares the square with the Panama Metropolitan Cathedral 1688, the Interoceanic Museum, the Municipal Palace of 1910 and the Central Hotel. It has partial view of the Plaza and the sea, in a Presidential Palace street.

Guest favorite
A modern living area features a brown sofa and two accent chairs positioned around glass-topped tables. A geometric area rug adds visual interest to the space. A staircase leads to the upper level, while large tiles reflect natural light entering through the nearby windows.
Loft in Panamá
4.95 out of 5 average rating, 20 reviews

Entire Apartment #7, 20 minutes from the airport

Comfortable and cozy loft on Avenida la Pulida! Equipped for executives and couples, this loft apartment features a bedroom with a queen bed, a full bathroom, a fully equipped kitchen, a living/dining room, a Smart TV, air conditioning, a water heater, a laundry area, and a walk-in closet. Just an 8-minute walk from the Cincuentenario Metro Station and with easy access to any point in the city. Located in a quiet and discreet central building. Enjoy a perfect stay! Parking available.

The spacious bedroom features a king-sized bed with crisp white linens, complemented by wooden accents and stone walls. Two bedside lamps offer soft lighting. A striking red chair adds a modern touch to the warm wooden floor, enhancing the contemporary aesthetic of the suite.
Loft in Panamá
4.82 out of 5 average rating, 224 reviews

★Large & Sunny SUITE in Historic District★

✨ Spacious penthouse suite full of character in the heart of Panama 🌴 Built into beautiful Calicanto stone walls, with warm wooden details and unique artwork 🎨, this stylish space is perfect for both relaxing and working remotely 💻 Enjoy comfortable king-size beds 🛏️, a modern kitchen and bathroom 🚿, TV in every bedroom 📺, strong WiFi 📶, and a private balcony with lovely views 🌅 ⭐ Everything you need for your Panama experience ⭐

Guest favorite
A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.
Loft in Panamá
4.92 out of 5 average rating, 117 reviews

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Top guest favorite
A modern dining area features a glass table surrounded by four white chairs. The space is enhanced by high ceilings and a staircase leading to an upper level, which showcases minimalist design elements and neutral tones.
Loft in Marbella
5 out of 5 average rating, 16 reviews

The Urban Loft #206 | La Résidence Panamá

Contemporary comfort for the modern traveler. This 69-71 m² suite includes 2 bedrooms (king and queen bed), sofa, 2 bathrooms, full kitchen, washer/dryer, coffee machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With a blend of modern design, central location, and thoughtful amenities, we create a space built for your comfort and productivity.

Top guest favorite
Loft in Panama City
5 out of 5 average rating, 32 reviews

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Superhost
Loft in Panamá
4.85 out of 5 average rating, 33 reviews

Modern 2BR/2BA Loft Near Casco Viejo

Loft moderno en Casa Korsi, más que un lugar para dormir: una experiencia con estilo en el corazón de Santa Ana, a pocos pasos del Casco Viejo. Ubicación ideal para moverte caminando entre restaurantes, bares y plazas, rodeado de la energía auténtica de la ciudad. Espacio cómodo, bien pensado y con carácter local. Perfecto tanto para escapadas como para trabajo remoto, si buscas buena ubicación y un ambiente con personalidad.

Guest favorite
Loft in Panamá
5 out of 5 average rating, 9 reviews

El Rincón Oliva: Apartment with View, Pool and Charm

Discover Centriqo, a modern haven in the heart of Howard Panama Pacifico. Surrounded by abundant vegetation and just steps from supermarkets, restaurants, cafes, and social spaces, it's the perfect place to disconnect from the city's rhythm without giving up convenience. Ideal for travelers flying from Balboa Airport or for those seeking tranquility, fresh air, and a relaxing stay in an exclusive and serene setting.

Superhost
Loft in Panamá
4.89 out of 5 average rating, 288 reviews

Amazing Loft with the Best view of Casco viejo for

Beautiful loft located in the center of Casco Antiguo, the most touristic area of Panama. This spacious loft comfortably accommodates up to 6 guests, making it perfect for families or groups of friends. Come, enjoy and relax in this impressive loft, featuring an incredible view of the Panama Cathedral. You can easily visit museums, bars, restaurants, and historic churches located just a few meters away.

Superhost
An interior view showcases a modern, multi-level loft with a wooden staircase leading to the upper loft area. Soft lighting creates ambient hues throughout the open space, highlighting the kitchen and living areas, where stylish furniture is arranged for comfort. Exposed stone walls add texture.
Loft in Panamá
4.89 out of 5 average rating, 329 reviews

2B Loft Studio | Design By Paradox

PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

Guest favorite
A well-lit room features two spacious beds, each made with light-colored bedding. A small seating area includes a wooden stool and a flat-screen television mounted on the wall. Large windows provide views of the surrounding landscape, allowing natural light to brighten the space.
Loft in San Miguelito
4.83 out of 5 average rating, 66 reviews

Spanish

Relax with the whole family or friends in this peaceful place in Panama City, just 10 minutes from Tocumen Airport, close to main roads, you can take the metro, bus or taxi service easily and quickly to visit Panama City, close to MetroMall and Los Pueblos shopping center. A super cool apartment... we're sure you'll love the breeze in this place.

Guest favorite
A cozy living area is highlighted by a light-colored wooden table placed on a textured rug. Two comfortable chairs face the table, with a small plant centerpiece and books visible. Natural light floods the space through large windows, revealing lush greenery outside.
Loft in Panamá
4.95 out of 5 average rating, 81 reviews

Canal Loft

Apartment on 1st floor, ideal for couples who love good taste, tranquility and comfort. Cerca del apartamento hay senderos hacia el el Canal de Panamá, colinas y selva. Apartment on the 1st Floor, ideal for couples who love good taste, tranquility and comfort. Near the apartment there are trails to the Panama Canal, hills and jungle.

Popular amenities for Panama City loft rentals

Quick stats about loft rentals in Panama City

  • Total vacation rentals

    Explore 60 vacation rentals in Panama City

  • Nightly prices starting at

    Panama City vacation rentals start at ﺩ.ﺇ73 per night before taxes and fees

  • Verified guest reviews

    Over 2,490 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wi-Fi availability

    50 of Panama City vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Panama City rentals

  • 4.8 Average rating

    Panama City stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore

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