
Loft vacation rentals in Panama City
Find and book unique loft rentals on Airbnb
Quick stats about loft rentals in Panama City

Total vacation rentals
Explore 70 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

Verified guest reviews
Over 2,730 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Vacation rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
60 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated loft rentals in Panama City
Guests agree: these loft rentals are highly rated for location, cleanliness, and more.

Entire Apartment #7, 20 minutes from the airport
Comfortable and cozy loft on Avenida la Pulida! Equipped for executives and couples, this loft apartment features a bedroom with a queen bed, a full bathroom, a fully equipped kitchen, a living/dining room, a Smart TV, air conditioning, a water heater, a laundry area, and a walk-in closet. Just an 8-minute walk from the Cincuentenario Metro Station and with easy access to any point in the city. Located in a quiet and discreet central building. Enjoy a perfect stay! Parking available.
4.96 out of 5 average rating, 27 reviews
Central Artsy Colonial 2BR Loft with Balcony
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!
4.99 out of 5 average rating, 179 reviews
The Urban Loft #206 | La Résidence Panamá
Contemporary comfort for the modern traveler. This 69-71 m² suite includes 2 story, 2 bedrooms (king and queen bed), sofa, 2 bathrooms, full kitchen, washer/dryer, coffee machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With a blend of modern design, central location, and thoughtful amenities, we create a space built for your comfort and productivity.
5.0 out of 5 average rating, 20 reviews
Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
4.9 out of 5 average rating, 127 reviews
Stylish 2BR/2BA Loft Near Casco Viejo
Loft moderno en Casa Korsi, más que un lugar para dormir: una experiencia con estilo en el corazón de Santa Ana, a pocos pasos del Casco Viejo. Ubicación ideal para moverte caminando entre restaurantes, bares y plazas, rodeado de la energía auténtica de la ciudad. Espacio cómodo, bien pensado y con carácter local. Perfecto tanto para escapadas como para trabajo remoto, si buscas buena ubicación y un ambiente con personalidad.
4.87 out of 5 average rating, 38 reviews
Studio Apartment near Costa del Este
Modern and Central Loft: Comfort at the Best Price. Close to Costa del Este Enjoy this fully equipped loft in a strategic location, close to supermarkets and transportation. Ideal for business or pleasure. It has: *Queen-sized bed. *Sofa-Bed * Full kitchen *Air conditioning. * Hot water and TV A space designed for a pleasant and functional stay in the city. Note: No pets Book your perfect stay in Panama now!
4.85 out of 5 average rating, 26 reviews
2B Loft Studio | Design By Paradox
Private 40 m² loft studio in Santa Ana, about a 5-minute walk from Casco Viejo. Loft Studio sleeps up to 3 guests with a Queen bed on a mezzanine and a sofa bed, plus a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a TV with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.
4.89 out of 5 average rating, 364 reviews
Amazing Loft with the Best view of Casco viejo for
Beautiful loft located in the center of Casco Antiguo, the most touristic area of Panama. This spacious loft comfortably accommodates up to 6 guests, making it perfect for families or groups of friends. Come, enjoy and relax in this impressive loft, featuring an incredible view of the Panama Cathedral. You can easily visit museums, bars, restaurants, and historic churches located just a few meters away.
4.89 out of 5 average rating, 318 reviews
Between Luxury and Nightclubs: Casco Premium Stay
✨ A space designed for your total relaxation ✨ Immerse yourself in an experience of total comfort in a quiet, cozy, and carefully designed environment to unwind from stress and reconnect with yourself. Here, every moment feels light, comfortable, and carefree. You will enjoy a quiet, private, and peaceful atmosphere, ideal for deep rest, quiet work, or simply relaxing at your own pace.
4.86 out of 5 average rating, 29 reviews
Airport / Wi-Fi / Private Loft / Studio / Cozy
📍 Location: Don Bosco Urbanization #2 Private, comfortable, and functional loft, ideal for your stay Includes: 🛏️ Bed 🛋️ Sofa bed 📺 -Smart TV 🍳 - Stocked kitchen 📶 Fast Wi-Fi ❄️ A/C 🚿 Private bath with hot water 📍 Located near the airport, with easy access to restaurants, supermarkets, and transportation. Ideal for solo travelers, couples, or groups of 3.
4.91 out of 5 average rating, 23 reviews
español
Relax with the whole family or friends in this peaceful place in Panama City, just 10 minutes from Tocumen Airport, close to main roads, you can take the metro, bus or taxi service easily and quickly to visit Panama City, close to MetroMall and Los Pueblos shopping center. A super cool apartment... we're sure you'll love the breeze in this place.
4.84 out of 5 average rating, 76 reviews
Corcho rooms #1 - queen rom with a balcony
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.
4.89 out of 5 average rating, 246 reviewsPopular amenities for Panama City loft rentals
Family-friendly loft rentals

Modern apt in downtown with balcony and laundry
4.7 out of 5 average rating, 182 reviews
Open-space apartment / Steps from the Old Town
4.67 out of 5 average rating, 3 reviews
Malaika Home

Your Musical Haven

Stay with Ricardo - Private Room
5.0 out of 5 average rating, 23 reviews
Studio apartment in the heart of Panama City
4.67 out of 5 average rating, 6 reviews
Entire Apartment #4, 20 minutes from the airport
4.96 out of 5 average rating, 71 reviews
Cozy apartment | Metro 8 min. away
5.0 out of 5 average rating, 4 reviewsLoft rentals with a washer and dryer

El Rincón Oliva: Apartment with View, Pool and Charm
5.0 out of 5 average rating, 18 reviews
★Large & Sunny SUITE in Casco Antiguo★
4.81 out of 5 average rating, 243 reviews
Romantic Loft Casco Viejo • Plaza Views & Top Spot
4.83 out of 5 average rating, 108 reviews
The Don Quixote Loft by AcoModo (Ocean View)
4.85 out of 5 average rating, 55 reviews
the 23 rd escape
5.0 out of 5 average rating, 14 reviews
Experience the Old Town at night
4.78 out of 5 average rating, 50 reviews
w* | Luxury 1BR in Marbella w/ Balcony & View

Infinity pool • Balboa • Panoramic views • Helmet
New place to stayOther loft vacation rentals

Quiet Retreat in Casco | Premium Quiet Living
4.6 out of 5 average rating, 5 reviews
The Urban Loft #204 | La Résidence Panamá

Mirador del Pacifico* Suite 10

Luxury Loft, 23rd Floor / Panoramic View + Resort-Style
4.88 out of 5 average rating, 25 reviews
The sands*premiun stay piscina infinita
4.61 out of 5 average rating, 28 reviews
La Castellana Loft By AcoModo @ Casco Viejo
4.8 out of 5 average rating, 35 reviews
10th floor suite
4.75 out of 5 average rating, 12 reviews
Luxury Apartment Ideal for Executives and Couples
4.71 out of 5 average rating, 14 reviewsDestinations to explore
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