Loft vacation rentals in Panama City

A comfortable sleeping area is presented with a spacious bed covered in a soft, patterned blanket. Lively artwork featuring tulips adorns the wall above, while bedside tables with lamps provide gentle illumination. Dark curtains frame the window, and air conditioning is installed overhead.

4.96 out of 5 average rating, 69 reviews

Entire Apartment #4, 20 minutes from the airport

Comfortable and cozy apartment on Av. la Pulida, 8 minutes from the Cincuentenario metro station. For business travelers and couples, this apartment features a bedroom with a full bed, a TV in the room, a full bathroom with hot water, a fully equipped kitchen, a living-dining room, a Smart TV, air conditioning, a laundry room, and a closet. It's just 8 minutes from the metro station and offers easy access to any point in the city. Centrally located, yet quiet. Enjoy a perfect stay!

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A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.

4.93 out of 5 average rating, 124 reviews

Loft 3b Casco Antiguo Best! Son 150 m2 (492 feet)

Sumérgete en el encanto histórico y la elegancia moderna de nuestro loft de 3 recámaras y 150 m2, en el corazón del Casco Antiguo. Con pisos de madera que irradian calidez y una cocina moderna de diseño abierto ideal para compartir, este espacio garantiza unas vacaciones memorables. Situado en la Avenida A, te encontrarás a solo unos pasos de exquisitos restaurantes, museos, iglesias coloniales y los codiciados rooftops del Casco, convirtiendo cada día en una aventura.

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Top guest favorite

A balcony is visible with colorful tiled tables and black wrought iron chairs. Lush potted greenery adds a natural touch, while surrounding buildings with terracotta roofs can be seen in the background. The scene is illuminated by daylight, enhancing the vibrant colors.

4.99 out of 5 average rating, 179 reviews

Patty’s Casco 2BR Loft | Balcony & Personal Touch

“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

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5.0 out of 5 average rating, 16 reviews

El Rincón Oliva: Apto con Vista, Piscina y Encanto

Descubre Centriqo, un refugio moderno en el corazón de Howard Panamá Pacífico. Rodeado de abundante vegetación y a solo pasos de supermercados, restaurantes, cafeterías y espacios sociales, es el lugar perfecto para desconectarte del ritmo de la ciudad sin renunciar a la conveniencia. Ideal para viajeros que vuelan desde el aeropuerto de Panamá Pacífico o para quienes buscan tranquilidad, aire fresco y una estadía relajante en un entorno exclusivo y sereno.

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4.84 out of 5 average rating, 25 reviews

Apartamento tipo estudio cerca de Costa del Este

Loft Moderno y Céntrico: Confort al Mejor Precio. Cerca de Costa del Este Disfruta de este loft totalmente equipado en ubicación estratégica, cerca de supermercados y transporte. Ideal para negocios o placer. Cuenta con: *Cama Queen. *Sofa-Cama *Cocina completa *Aire acondicionado. * Agua caliente y TV Espacio diseñado para una estancia placentera y funcional en la ciudad. Nota: No mascotas ¡Reserva ahora tu estadía perfecta en Panamá!

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4.88 out of 5 average rating, 24 reviews

Entre Lujo y Discotecas Casco Premium Stay

✨ Un espacio pensado para tu descanso absoluto ✨ Sumérgete en una experiencia de confort total en un ambiente tranquilo, acogedor y cuidadosamente diseñado para desconectarte del estrés y reconectar contigo mismo. Aquí, cada momento se siente ligero, cómodo y sin preocupaciones. Disfrutarás de una atmósfera silenciosa, privada y armoniosa, ideal para descansar profundamente, trabajar con tranquilidad o simplemente relajarte a tu propio ritmo.

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5.0 out of 5 average rating, 20 reviews

A modern dining area features a glass table surrounded by four white chairs. The space is enhanced by high ceilings and a staircase leading to an upper level, which showcases minimalist design elements and neutral tones.

Loft in Bella Vista

The Urban Loft #206 | La Résidence Panamá

Contemporary comfort for the modern traveler. This 69-71 m² suite includes 2 story, 2 bedrooms (king and queen bed), sofa, 2 bathrooms, full kitchen, washer/dryer, coffee machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With a blend of modern design, central location, and thoughtful amenities, we create a space built for your comfort and productivity.

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Superhost

4.86 out of 5 average rating, 37 reviews

Stylish 2BR/2BA Loft Near Casco Viejo

Loft moderno en Casa Korsi, más que un lugar para dormir: una experiencia con estilo en el corazón de Santa Ana, a pocos pasos del Casco Viejo. Ubicación ideal para moverte caminando entre restaurantes, bares y plazas, rodeado de la energía auténtica de la ciudad. Espacio cómodo, bien pensado y con carácter local. Perfecto tanto para escapadas como para trabajo remoto, si buscas buena ubicación y un ambiente con personalidad.

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Superhost

An interior view showcases a modern, multi-level loft with a wooden staircase leading to the upper loft area. Soft lighting creates ambient hues throughout the open space, highlighting the kitchen and living areas, where stylish furniture is arranged for comfort. Exposed stone walls add texture.

4.89 out of 5 average rating, 357 reviews

2B Loft Studio | Design By Paradox

Private 40 m² loft studio in Santa Ana, about a 5-minute walk from Casco Viejo. Loft Studio sleeps up to 3 guests with a Queen bed on a mezzanine and a sofa bed, plus a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a TV with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.

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4.84 out of 5 average rating, 75 reviews

A well-lit room features two spacious beds, each made with light-colored bedding. A small seating area includes a wooden stool and a flat-screen television mounted on the wall. Large windows provide views of the surrounding landscape, allowing natural light to brighten the space.

Loft in San Miguelito

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Relájate con toda la familia o amigos en este tranquilo lugar en la ciudad de Panamá, a tan solo 10 minutos del aeropuerto de Tocumen, cerca a vias principales, puedes tomar el metro, el autobus o servicio de taxi de manera facil y rapida para visitar la ciudad de Panamá, cerca a centro comercial MetroMall y Los Pueblos. Un apartamento super fresco... estamos seguros que vas a amar la brisa en este lugar.

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The image captures a stunning view from a balcony, overlooking a historic cathedral with intricate architectural detailing. The white buildings frame the scene, and cloudy skies add a soft contrast to the vibrant structure of the cathedral, highlighting its grandeur.

4.88 out of 5 average rating, 313 reviews

Amazing Loft with the Best view of Casco viejo for

Beautiful loft located in the center of Casco Antiguo, the most touristic area of Panama. This spacious loft comfortably accommodates up to 6 guests, making it perfect for families or groups of friends. Come, enjoy and relax in this impressive loft, featuring an incredible view of the Panama Cathedral. You can easily visit museums, bars, restaurants, and historic churches located just a few meters away.

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