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Apartment vacation rentals in Panama City

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Top-rated apartment rentals in Panama City

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Guest favorite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Apartment in Panama City
5 out of 5 average rating, 40 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Superhost
Apartment in Panamá
5 out of 5 average rating, 4 reviews

Incredible Renovated Apartment in Casco Viejo

Disfruta de un loft único en el corazón de Casco Viejo, ubicado en la emblemática Calle 4ta. Este apartamento ha sido totalmente remodelado, combinando a la perfección el encanto histórico de sus muros originales con un diseño moderno y elegante. La doble altura, la pared de piedra restaurada y los detalles artesanales en los pisos crean un ambiente acogedor y sofisticado. Su distribución abierta con sala, comedor y cocina integrada lo convierten en un espacio ideal para relajarse y compartir.

Guest favorite
A spacious outdoor area features wooden dining tables surrounded by potted plants. The space includes a plunge pool, comfortable seating, and a hammock for relaxation, with views of the nearby structures and the sky above.
Apartment in Panamá
4.87 out of 5 average rating, 357 reviews

Casco Viejo 360° View Old Tower Penthouse

Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Top guest favorite
A cozy living area with a large window offering a panoramic view of the city lights at night. A comfortable sofa is positioned to face a television, creating a relaxed space. The room's walls are softly illuminated, enhancing the viewing experience.
Apartment in Panamá
4.97 out of 5 average rating, 118 reviews

The Spot Panama - Comfy, great view & much more

Ideally located in Panama City Panama 🇵🇦 we're just 15-20 minutes from Tocumen Airport 🛩 . Approximately 10 minutes from Albrook Mall, SoHo Mall, Alta Plaza, Multiplaza and much more! Enjoy easy access to supermarkets and restaurants!. Experience peace of mind with 24/7 security and outstanding facilities: pool, gym, and free parking! More than a stay, it's a chance to shop, unwind, and soak in Panama City views. Don't hesitate- Book instantly or contact us if you have any questions.

Guest favorite
A clear blue swimming pool is seen, reflecting sunlight under a bright sky. Surrounding greenery provides privacy, while a modern building stands nearby, featuring large balconies. The pool area is designed for relaxation and leisure.
Apartment in Panamá
4.92 out of 5 average rating, 203 reviews

Cozy apartment near Casco Viejo

Enjoy a stay in one of the most exclusive areas in the center of Panama, few minutes from Casco Viejo the Cozy Apartment City Center offers free WiFi, air conditioning and stunning views amidst skyscrapers. The apartment has one bedroom with a queen-size bed, a bath and shower, a sofa bed, two smart TV, a fully equipped kitchen, a washer and dryer, and a half bath. On the property there is a work area, a gymnasium, a community pool, and a barbeque area FREE PARKING

Top guest favorite
A bright and airy living space features large floor-to-ceiling windows offering city views. Sleek marble floors complement minimalist furnishings, including two neutral sofas and a stylish coffee table. An open kitchen area is visible in the background, enhancing the overall modern design.
Apartment in Marbella
4.98 out of 5 average rating, 45 reviews

Unique Luxury 3-story Loft at the Yoo

Experience the luxury of a world renowned Philippe Starck designed building. Our 3-bedroom sanctuary is a unique 3-story loft that boasts breathtaking city views, an open-plan kitchen, sleek marble floors, and premium amenities. Steps away from Panama City’s premier attractions, shopping, and dining. Dive into top-tier amenities: a pristine pool, state-of-the-art gym, relaxing spa, and three of the best restaurants in the city! Embrace Panama in unmatched style.

Top guest favorite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in Panamá
4.98 out of 5 average rating, 151 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favorite
A modern living area features a comfortable sofa, a dining table with chairs, and a fully equipped kitchen. Large windows allow natural light to brighten the space, showcasing views of the city skyline. The decor is minimalistic, with potted plants adding a touch of greenery.
Apartment in Panamá
5 out of 5 average rating, 27 reviews

Modern and Central · Nice Condo in the Heart of Pty

¡Modern 50 m2 apartment located on Calle 50, in the heart of Panama City!. With access to the best in art, culture, business, finance, sports, shopping, food, and nightlife. * The space has a room with a queen size bed, full bathroom, smart TV and desk with monitor (HDMI cable) for those traveling without disconnecting from work. * The living room has a comfortable sofa bed, full bathroom, dining room and kitchen equipped for kitchen lovers!.

Top guest favorite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Panamá
4.97 out of 5 average rating, 119 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favorite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Apartment in Panamá
4.93 out of 5 average rating, 101 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Guest favorite
Apartment in Panamá
4.98 out of 5 average rating, 123 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favorite
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Apartment in Panama City
4.9 out of 5 average rating, 155 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Popular amenities for Panama City apartment rentals

Quick stats about apartment rentals in Panama City

  • Total vacation rentals

    Explore 2,770 vacation rentals in Panama City

  • Nightly prices starting at

    Panama City vacation rentals start at ﺩ.ﺇ37 per night before taxes and fees

  • Verified guest reviews

    Over 71,040 verified reviews to help you choose

  • Family-friendly vacation rentals

    850 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 990 rentals that welcome pets

  • Vacation rentals with a pool

    1,730 properties feature pools

  • Rentals with dedicated workspaces

    1,720 properties have a dedicated workspace

  • Wi-Fi availability

    2,640 of Panama City vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

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