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Apartment vacation rentals in Panama City

Find and book unique apartments on Airbnb

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Popular amenities for Panama City apartment rentals

Apartment rentals with air conditioning

Guest favorite
An inviting seating area is highlighted by a light-colored sofa adorned with orange cushions. Natural stone walls add texture, while large windows allow natural light to fill the space. Lush green plants provide a touch of nature, enhancing the serene atmosphere.
Apartment in Panama City
5 out of 5 average rating, 29 reviews

Charming Oceanfront Apartment

RichardRating, 5 stars2 weeks ago
We really enjoyed the property. It was very roomy and more spacious than the pictures show. While the property is located in the tourist area, we were never bothered with any outside disturbances or noise. This was our first visit to Panama and first time in an AirBnb; we are so glad we chose this property and were really pleased with everything. We have absolutely nothing but great things to say about the property and our experience.
Guest favorite
A modern living area is presented with a light-colored sofa and stylish accent cushions. A glass coffee table is paired with a white armchair and a vibrant blue side table. Floor-to-ceiling windows provide a clear view of the ocean and allow natural light to brighten the space.
Apartment in Marbella
4.83 out of 5 average rating, 58 reviews

Apartamento Av. Balboa, Yoo&Arts

BryceRating, 5 stars1 week ago
Place is in a great location . Too has lots of amenities .
Guest favorite
A spacious bedroom is presented with floor-to-ceiling windows offering stunning city views. The bed features a plush, textured blanket, and a large flat-screen TV is mounted on the wall. The polished floor reflects the natural light streaming in, enhancing the airy ambiance.
Apartment in Costa del Este
4.97 out of 5 average rating, 31 reviews

Penthouse Panoramic View with Luxury Amenities

MichaelRating, 5 stars6 days ago
Would recommend for a vacation, clean and the host was very helpful with our check in. Comfortable and safe feeling location, there is also a food hub right across the street so that’s a plus.
Superhost
A spacious rooftop pool area is adorned with lounge chairs and tables, illuminated by soft lights. The pool's vibrant blue water contrasts with the city skyline, featuring tall buildings under a dusky sky, creating a tranquil space for relaxation.
Apartment in Marbella
4.8 out of 5 average rating, 20 reviews

Spacious Oceanfront Apartment

WillRating, 5 stars3 weeks ago
Accommodation matches the photo. Very easy access. And pleasant setting. Very responsive and attentive host.
Top guest favorite
The living area features a modern couch with decorative pillows, complemented by a striped accent chair. A round table and a decorative lamp add functionality. Sunlight streams through large windows, providing a partial view of the ocean and enhancing the spacious ambiance.
Apartment in Marbella
4.96 out of 5 average rating, 28 reviews

Unit 62A at the YOO Balboa ave. Sea View

SteveRating, 5 stars2 weeks ago
Very comfortable and well maintained. Great communication with hosts and corrected minor issue immediately. Thanks!
Top guest favorite
A cozy living area with a large window offering a panoramic view of the city lights at night. A comfortable sofa is positioned to face a television, creating a relaxed space. The room's walls are softly illuminated, enhancing the viewing experience.
Apartment in Panamá
4.98 out of 5 average rating, 87 reviews

The Spot Panama - Comfy, great view & much more

JoseRating, 5 stars3 days ago
SMALL, MODERN, COMFORTABLE, CLEAN, BEAUTIFUL APARTMENT. WITH AN EXCELLENT VIEW.....SUPER PRICE. THE ONLY SMALL INCIDENT WAS THAT THE BUILDING SECURITY GUARD WHO HELPED ME WAS EITHER NEW TO HIS JOB OR HAD ANOTHER EXPLANATION, BECAUSE I HAD TO SPEND MORE THAN HALF AN HOUR EXPLAINING AND SHOWING HIM MY IDENTIFICATION AND I COULD NOT ENTER, BECAUSE AS HE EXPLAINED TO ME, HE HAD NOT BEEN NOTIFIED. OTHERWISE, SUPER EXCELLENT ACCOMMODATION. FULLY RECOMMENDED.
Guest favorite
A bright living area features a comfortable sectional sofa adorned with turquoise cushions. A wooden coffee table displays various magazines. Natural light floods the space through large glass doors, which lead to a patio filled with greenery.
Apartment in Panama City
4.97 out of 5 average rating, 62 reviews

Quiet apartment in the heart of Casco with patio

RobertoRating, 5 stars2 months ago
Beautiful place to stay, near the historic places, restaurants and bars of the Old City.
Guest favorite
A panoramic view of the ocean is visible through large floor-to-ceiling windows. The soft curves of a modern chair are positioned by the window, inviting relaxation while taking in the serene water and sky.
Apartment in Panamá
4.94 out of 5 average rating, 51 reviews

Ocean Bliss | King Bed + Parking

AlexRating, 5 stars5 days ago
Excellent, the best, recommended

Apartment rentals with a hot tub

Superhost
A panoramic view captures the skyline of Panama City with numerous high-rise buildings against a backdrop of clear blue skies. Various boats are visible in the foreground on the water, highlighting the bustling maritime activity.
Apartment in Perico island
4.89 out of 5 average rating, 36 reviews

3 bedroom penthouse with spectacular views!

FrankRating, 5 stars2 months ago
Martin’s penthouse is our home away from home in Panama! We love the views, the cleanliness of the penthouse and the safety provided to the guests. We will continue to book this penthouse anytime that we visit Panama! We can’t wait to go back!
Guest favorite
A bright living area is presented with large windows that allow natural light to flow in. A spacious couch and a pair of stylish armchairs are arranged around a central area rug. A wall-mounted television and artwork enhance the modern design of the room.
Apartment in Costa del Este
5 out of 5 average rating, 6 reviews

Panama Luxury | Condo Suite 2BR

MarleneRating, 5 stars1 week ago
This apartment in Costa del Este is absolutely amazing! The view is stunning — you can see the skyline and ocean, and it truly feels like you’re in Miami. The apartment was super clean, modern, and cozy, with everything I needed to feel at home. I especially appreciated how Erick was always available and helpful during my stay. His support made everything even smoother. The location is perfect — safe, central, and close to shops, restaurants, and more. I recommend this place 100% and would definitely book again! Este apartamento en Costa del Este es simplemente increíble. ¡La vista es espectacular! Se ve el skyline y el mar, y de verdad se siente como estar en Miami. El apartamento estaba impecable, moderno y muy cómodo, con todo lo necesario para sentirse como en casa. Además, Erick estuvo siempre disponible para ayudarme en lo que necesitara, lo cual hizo la experiencia aún mejor. La ubicación es perfecta: segura, céntrica y cerca de todo. Recomiendo este lugar al 100% y sin duda v
Guest favorite
An open living area is showcased, featuring modern furniture with a touch of greenery above. A comfortable seating arrangement in warm tones complements a wall-mounted SMART TV. Large glass doors provide natural light, leading to a balcony with city views, enhancing the overall space.
Apartment in Panamá
4.91 out of 5 average rating, 22 reviews

3B - Simply Fabulous

PaulRating, 5 stars3 weeks ago
Bella Vita was an exceptional place to stay. When we arrived we had someone greet us and give us our keys and some instructions. The rooms were very clean and as shown in the pictures. The host was also responsive when we had to change the reservation a few times. Thank you for making Panama a wonderful trip!
Guest favorite
An expansive rooftop pool area is illuminated by soft lighting, surrounded by comfortable lounge chairs. A stylish bar is visible in the background, with the city skyline providing a stunning backdrop as twilight descends.
Apartment in Marbella
5 out of 5 average rating, 7 reviews

Suite Luxury 30th View , Cinta Costera Panama

SteveRating, 5 stars1 month ago
The place was great and exactly as described. Very comfortable as well. Exceptional host. Communication could not have been better. Victor went above and beyond what was required. Thank you!
Superhost
A spacious bedroom features a large bed with neutral bedding and contrasting pillows. The stone accent wall is complemented by soft lighting from pendant lamps. A bright yellow chair adds a splash of color, while sheer curtains frame a window, enhancing the overall ambiance.
Apartment in Panamá
4.82 out of 5 average rating, 67 reviews

Beautiful colonial condo with a hot tub and balcony

MarcelRating, 5 stars2 weeks ago
It was a pleasure to be a guest at Oddy. Communication was always very fast and hassle-free. The apartment is as shown in the photos and in the description. I was very satisfied with everything and recovered well. The location is in Casco Viejo and therefore ideally located for various restaurants and bars. Would come back in a heartbeat!
Top guest favorite
A modern living room features a light-toned sofa and a stylish armchair, complemented by a coffee table on a soft area rug. Floor-to-ceiling glass doors lead to a balcony with coastal views. Decorative plants and a sleek TV add to the room's contemporary appeal.
Apartment in Marbella
5 out of 5 average rating, 9 reviews

Luxurious Apartment Oceanfront View

ChristinaRating, 5 stars2 months ago
My husband and I stayed at José's place for a quick birthday trip and we loved it! Firstly, José is very responsive and is a great communicator. We felt right at home and most importantly we felt very safe. The apartment itself is gorgeous! Looks exactly like the pictures and that view is everything. The bed was comfortable and the shower was HOT. The building itself is very nice with amazing amenities inside like restaurants, a place for kids, spa, gym, and rooftop pool area. The building is also within walking distance to a lot of great restaurants and things to do. I would stay at José's place again in a heartbeat!
Superhost
A spacious outdoor pool area is defined by well-maintained green lawns and tropical palm trees. The pool features multiple sections with a clear blue water surface, surrounded by lounge chairs and shaded cabanas. A backdrop of lush, green hills adds to the tranquil setting.
Apartment in Panama
4.94 out of 5 average rating, 111 reviews

Tropical Paradise at Playa Bonita

CrystalRating, 5 stars2 months ago
Lovely views, excellent amenities and very hospital people. Would definitely stay again.
Superhost
A rooftop pool glistens under a clear blue sky, with modern buildings visible in the background. The pool area is surrounded by lounge chairs, creating an inviting space for relaxation and social interaction.
Apartment in Marbella
4.67 out of 5 average rating, 30 reviews

Apartment, Panama City.

JoseRating, 5 stars1 week ago
Everything as described, super easy check in and the building has 3 beautiful restaurants and a food market attached, great 1 night stay.

Weekly apartment rentals

Top guest favorite
A modern living area features a light-colored sectional sofa paired with two minimalist coffee tables. Large glass windows offer a panoramic view of the city skyline, allowing natural light to fill the space. Neutral tones are complemented by a warm overhead light fixture.
Apartment in Panamá
5 out of 5 average rating, 25 reviews

Cozy apartment in Panama

OscarRating, 5 stars2 weeks ago
I definitely give a 10 out of 10 to the place, spotless ultra clean very well stocked and with some extra supplies for you to use it, the communication with salvador was always great he answered me back pretty soon and everything worked out smooth during my reservation, I’m definitely giving a 5 stars and the recommendation for everyone looking for an stay in the area
Top guest favorite
An open living and kitchen area is displayed, featuring a modern design with a light color palette. Two high-backed bar stools are positioned at the kitchen counter, with a stainless steel refrigerator and sleek appliances visible. A comfortable sofa and low coffee table are arranged in the living space.
Apartment in Panamá
4.98 out of 5 average rating, 63 reviews

Centrally located, elegant and minimalist

AlessandraRating, 5 stars3 weeks ago
The flat was exactly as described. It was very cosy with hot water and in a great area. Jesús was extremely responsive and helpful. It was a great place to stay for a city break.
Guest favorite
A modern living space is highlighted by large floor-to-ceiling windows letting in natural light and offering views of the ocean. The area features a dining table, sleek white chairs, and plants, which add a touch of greenery to the interior.
Apartment in Panamá
4.96 out of 5 average rating, 23 reviews

OceanView Balcony •Remote Working• Near Multiplaza

WangRating, 5 stars4 weeks ago
It's a new apartment. Have a good view. 100% recommend
Guest favorite
A modern living area features a spacious gray sectional sofa accented with neutral cushions. A glass coffee table sits centrally, accompanied by decorative items. Large windows allow natural light to fill the space, showcasing views of the city and adding to the bright ambiance.
Apartment in Marbella
4.82 out of 5 average rating, 45 reviews

Apartment with Ocean&City views Avenida Balboa

ParisRating, 5 stars1 month ago
Beautiful place with a wonderful view! Joselyne made us feel very welcome and was very fast in responses! The views up top was amazing ! I will stay here again!
Top guest favorite
The image features a cozy seating area with a soft sofa and decorative cushions. A round table is set for two, showcasing glasses of water and a small potted plant. In the background, a panoramic view of high-rise buildings against a clear blue sky is visible.
Apartment in Panamá
4.98 out of 5 average rating, 44 reviews

Classy, New and Sea View Condo • Best Location!

MatthewRating, 5 stars3 weeks ago
Excellent stay. Conveniently located, good food options nearby, warm staff, nice gym, amazing pool. Highly communicative host. Probably the next place I stayed in Panama City!!
Guest favorite
A bright living area is furnished with a comfortable sofa and decorative elements, including potted plants and wall art. Natural light floods the space through large windows, while a dining table and kitchen bar are visible in the background, creating an inviting atmosphere for relaxation.
Apartment in Panamá
4.94 out of 5 average rating, 131 reviews

w* | Graceful 2BR in Casco Viejo

TimothyRating, 5 stars1 week ago
The condo is cleaned and location is very centrally located, walkable to restaurants, museums, churches, etc. Host (Juan) is responsive. The only thing is the hardwood floor is making noise every steps inside the condo while other people still sleeping, you can hear each steps. Overall we had a great experienced.
Superhost
A spacious outdoor area features a modern infinity pool, with lounge chairs arranged beside it. A clear view of the city skyline is visible in the distance, while the water reflects the bright sky.
Apartment in Panamá
4.81 out of 5 average rating, 100 reviews

Ocean View private Studio Apartment

DerrickRating, 5 stars1 month ago
The apartment was a bit on the small size but the views were amazing. I would recommend adding an iron or steamer to the room. It was challenging getting wrinkles out our clothes. The apartment is located centrally to everything in Panama which makes it amazing…Will definitely book again if we travel to Panama again!!!
Guest favorite
The private rooftop features a light pink wall and gray tiled flooring, equipped with two black wicker chairs, a matching table, and a lounge chair. A small potted plant sits on the table, and an umbrella provides shade against the skyline view.
Apartment in Panamá
4.96 out of 5 average rating, 53 reviews

Apt w/ Private Rooftop in Vibrant Santa Ana

KatherineRating, 5 stars1 month ago
Great, modern apartment! The rooftop was particularly lovely and a nice place to sit out at night. Josue was an amazing host- very flexible and gave fantastic recommendations. Walkable to restaurants in Casco Viejo and there’s a good grocery store less than a minute walk away. There’s also a soccer field across the street that is fun to watch local games. The immediate neighborhood could look a little rough, but I never had a problem and felt safe as a solo female traveler. Ubers are super easy to get if you prefer.

Quick stats about apartment rentals in Panama City

  • Total rentals

    2.6K properties

  • Nightly prices starting at

    ﺩ.ﺇ37 before taxes and fees

  • Total number of reviews

    62K reviews

  • Family-friendly rentals

    860 properties are a good fit for families

  • Pet-friendly rentals

    870 properties allow pets

  • Rentals with a pool

    1.6K properties have a pool

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