
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,660 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at ﺩ.ﺇ 37 per night before taxes and fees

Verified guest reviews
Over 49,930 verified reviews to help you choose

Pet-friendly vacation rentals
Find 710 rentals that welcome pets

Vacation rentals with a pool
930 properties feature pools

Rentals with dedicated workspaces
1,020 properties have a dedicated workspace

Wi-Fi availability
1,590 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Round House River Dreams Cerro Azul
Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.

Apartment with unique views to remember
Pasarás una Experiencia con estilo, alojamiento céntrico. acceso a líneas de buses y el Metro, restaurante , grocery store 24 horas, y una vida nocturna genial, casinos, cinta costera, iglesia del Carmen. casco antiguo a minutos en uber. compras. Soho Mall, Multi Plaza Mall y Albrook Mall. Piscina para adultos y niños. Bar, restaurante, rooftop vistas panorámicas, coworking, gym. Una habitación Con cama queen y un sofá cama en la sala para huéspedes extras (costo xtra 15.00 pp x noche)

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, you will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. This restored- colonial building was built in the year 1850, and features some of the original "calicanto" walls. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Amazing Loft with the Best view of Casco viejo for
Beautiful loft located in the center of Casco Antiguo, the most touristic area of Panama. This spacious loft comfortably accommodates up to 6 guests, making it perfect for families or groups of friends. Come, enjoy and relax in this impressive loft, featuring an incredible view of the Panama Cathedral. You can easily visit museums, bars, restaurants, and historic churches located just a few meters away.
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Suite Luxury 30th View Yoo Panamá & Arts Tower

Luxury Apartment With Private Beach And Sea View

Cabin near the city, luxurious treehouse

New Flat with Ocean + City Views

Apartment Av. Balboa, Yoo&Arts

Tropical Paradise at Playa Bonita

Panama Dream View Escape

Luxurious country house, pleasant climate, with fireplace, jacuzzi, pool table, barbecue area, fire pit and more...
Family- and pet-friendly home rentals

Beautiful House in Panama w/ King Beds + Pool

Aparthotel Sevilla Suites - 3

Spacious oceanfront apartment

Lovely & Cozy central apartment in Casco Viejo

Cozy 2 Bedroom w/ Splash Pool

Luxury apartment in downtown Panama, banking area

Amazing loft with Casco charm in the best location

k*| Delightful 1 BR w/King Bed in Calle 50
Family-friendly home rentals with a pool

Your Home Facing the Sea

Old Town & Ocean View

Nice duplex house with a swimming pool.

Large Apartment in La Cuadra - Casco | By Alura

Luxury oceanfront apartment on the coastal strip

Mini Design Apartment

Cerro Azul, Country House with Heated Pool.

Breathtaking Views Mansion w/King Beds
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- Things to do Panama
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