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Family-friendly vacation rentals in Panama City

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Panama City

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in Panamá
4.91 out of 5 average rating, 181 reviews

Yoo Panama, piso 54 cómodo y acogedor.

Hermoso departamento ubicado en el piso 54 del más lujoso edificio de Panama. Areas diseñadas por el Diseñador Philip Stark. Tiene 134 metros, está completamente amoblado, cuenta con un dormitorio, walking closet, un baño completo, sala comedor y cocina abiertos, medio baño social, terraza, cuarto de lavado. El edificio es un lugar único, con áreas comunales especiales y lujosas; 2 elegantes restaurantes; 2 piscinas; Gym; SPA; 2 canchas de squash; salsa de póker, lobby con mesa de billa, etc.

Top guest favorite
A cozy living area with a large window offering a panoramic view of the city lights at night. A comfortable sofa is positioned to face a television, creating a relaxed space. The room's walls are softly illuminated, enhancing the viewing experience.
Apartment in Panamá
4.97 out of 5 average rating, 116 reviews

The Spot Panama - Comfy, great view & much more

Ideally located in Panama City Panama 🇵🇦 we're just 15-20 minutes from Tocumen Airport 🛩 . Approximately 10 minutes from Albrook Mall, SoHo Mall, Alta Plaza, Multiplaza and much more! Enjoy easy access to supermarkets and restaurants!. Experience peace of mind with 24/7 security and outstanding facilities: pool, gym, and free parking! More than a stay, it's a chance to shop, unwind, and soak in Panama City views. Don't hesitate- Book instantly or contact us if you have any questions.

Guest favorite
A living room area features a stone wall complemented by a wooden floor. A dining table with a marble top is accompanied by decorative poufs. Comfortable seating is arranged for relaxation, with light filtering through large windows overlooking a lush outdoor space.
Apartment in Panamá
4.83 out of 5 average rating, 108 reviews

Iconic Double Apt with Pool Table Facing ArcoChato

Welcome to Casa Arco Chato, your retreat in the heart of Casco Viejo! This elegant property blends historic charm with modern comfort. It features two bedrooms (1 queen bed, 2 twin beds), a full kitchen, a living room, a dining room, two bathrooms, a balcony, and an in-house laundry room. Ideal for four people. Plus, you'll have exclusive access to the building across the street with its beautiful infinity pool. Enjoy an unforgettable stay in a warm, spacious, and fully equipped space.

Top guest favorite
A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.
Apartment in Panamá
4.93 out of 5 average rating, 269 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Guest favorite
A clear blue swimming pool is seen, reflecting sunlight under a bright sky. Surrounding greenery provides privacy, while a modern building stands nearby, featuring large balconies. The pool area is designed for relaxation and leisure.
Apartment in Panamá
4.92 out of 5 average rating, 203 reviews

Cozy apartment near Casco Viejo

Enjoy a stay in one of the most exclusive areas in the center of Panama, few minutes from Casco Viejo the Cozy Apartment City Center offers free WiFi, air conditioning and stunning views amidst skyscrapers. The apartment has one bedroom with a queen-size bed, a bath and shower, a sofa bed, two smart TV, a fully equipped kitchen, a washer and dryer, and a half bath. On the property there is a work area, a gymnasium, a community pool, and a barbeque area FREE PARKING

Guest favorite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in Panamá
4.98 out of 5 average rating, 149 reviews

Escápate al Corazón de Casco con Balcón Privado

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favorite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Panamá
4.97 out of 5 average rating, 118 reviews

Apartamento de lujo Panamá centro, área bancaria

Contamos con una ubicación estratégica justo sobre la vía principal de Panamá (Calle 50) Bella Vista, te encontraras ubicado en el corazón del área bancaria. Si vienes por trabajo o vacaciones, este es el lugar ideal, encontrarás todo tipo de restaurantes a los alrededores, comercios, centro comerciales, tendrás la Cinta Costera a tan solo 10 minutos a pie donde podrás pasear o ejercitarte. Diversión y disfrute a pocos pasos

Guest favorite
Apartment in Panamá
4.98 out of 5 average rating, 123 reviews

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

Guest favorite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Apartment in Panamá
4.93 out of 5 average rating, 99 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Top guest favorite
Condo in Panama
4.99 out of 5 average rating, 257 reviews

Patty’s Cozy Studio with K bed in Casco Viejo

Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!

Top guest favorite
A modern apartment interior features a laundry area with stacked appliances alongside a sleek kitchen counter. A living space with a comfortable seating arrangement is visible, complemented by large windows offering expansive views of the city skyline and waterfront.
Apartment in Panama City
5 out of 5 average rating, 101 reviews

Exclusivo Ocean View 2BR/2BATH/Sky High & Rooftop!

Apartamento moderno de lujo en la Cinta Costera. Ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño espacioso, diseño elegante y electrodomésticos modernos. Amenidades: seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Cerca de supermercados y una gran oferta gastronómica. Ciudad de Panamá – Panamá.

Superhost
An interior view showcases a modern, multi-level loft with a wooden staircase leading to the upper loft area. Soft lighting creates ambient hues throughout the open space, highlighting the kitchen and living areas, where stylish furniture is arranged for comfort. Exposed stone walls add texture.
Loft in Santa Ana
4.89 out of 5 average rating, 283 reviews

Loft Studio | By Paradox

PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

Popular amenities for Panama City family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Panama City

  • Total vacation rentals

    Explore 1,480 vacation rentals in Panama City

  • Nightly prices starting at

    Panama City vacation rentals start at ﺩ.ﺇ37 per night before taxes and fees

  • Verified guest reviews

    Over 42,770 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 600 rentals that welcome pets

  • Vacation rentals with a pool

    890 properties feature pools

  • Rentals with dedicated workspaces

    930 properties have a dedicated workspace

  • Wi-Fi availability

    1,400 of Panama City vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore