
House vacation rentals in Panama City
Find and book unique houses on Airbnb
Quick stats about house rentals in Panama City

Total vacation rentals
Explore 490 vacation rentals in Panama City

Verified guest reviews
Over 7,960 verified reviews to help you choose

Family-friendly vacation rentals
200 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 170 rentals that welcome pets

Vacation rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
230 properties have a dedicated workspace

Wi-Fi availability
460 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

King Beds | 4BR | BBQ & Garden | pets ok!
Nestled in a prime central location, this lovely house offers guests unparalleled convenience and uniqueness. Find yourself just a swift 10-minute Uber ride away from the bustling heart of downtown, making exploration and nightlife easily accessible. One of the standout features of our home is the exclusive view of the Metropark, which you can relish from both the backyard and balcony – a serene panorama that's hard to beat. Finally sleep in supreme comfort with king-sized beds featured.

Family-Friendly Panama Canal Home with Fenced Yard
Welcome to our 3-bedroom vacation rental in Cardenas, Panama Canal area! Perfect for families, this home boasts a kitchen with quality appliances, including a 6-burner gas stove and a large fridge. Relax in stylish bedrooms, featuring a king suite with a private bath, and enjoy the lush surroundings filled with wildlife. Located next to a park with sports courts, this kid-friendly neighborhood offers outdoor fun. Experience the unique blend of comfort and nature right at your doorstep!

Villa Flor house
Welcome to Casa Villa Flor — a comfortable and peaceful home located in the quiet San Antonio neighborhood. Conveniently located just 15 minutes from the airport, and within walking distance to MetroMall and the train station, making it easy to explore the area and travel around the city. Perfect for families or groups of up to 6 guests, the home includes: • Air conditioning • High-speed WiFi & Internet • Comfortable living spaces • Quiet residential atmosphere • No smoking

Large Private Residence in an Excellent Area
House in the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall among others. Large comfortable residence for groups or families. Private parking for up to 2 cars 4 spacious bedrooms, 2 comfortable studios, living room, breakfast room, large terrace. *Kosher Option Available* House in one of the best areas of the country. Very quiet street, central, close to restaurants, pharmacies, mall, and more. Large, comfortable residence for groups.

House of the waterfalls
Your ideal escape: A hidden refuge in the Panamanian capital. Harmony between waterfalls and urban comfort. Rest in a natural environment, minutes away from everything. Wake up to birdsong and the relaxing sound of water. To make your stay more pleasant, we offer a swimming pool, pool table, board games, campfire area, spacious and equipped kitchen, three cozy rooms with private bathrooms. Enjoy a country experience to contemplate, share, or simply disconnect.

Spacious Family House Airport
Just 6 minutes from Tocumen International Airport, our comfortable house is an excellent option to rest and relax, a safe and quiet place, you have a 24-hour Supermarket with a Restaurant and Pharmacy 2 minutes away, 3 minutes from Tocumen Hospital and the Metro Station, 10 minutes from Los Pueblos Shopping Center and Metromall. In our house you can enjoy 3 bedrooms, 2 bathrooms, A/C, a large terrace, private parking, an equipped kitchen, Wi-Fi and Netflix.

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Private Studio 10 Min from the Airport!
Apartamento Entero 10 MINUTES FROM the Airport! The apartment is fully furnished, including appliances and kitchenware, toiletries, a living/dining room, a work table, and more. Only a few minutes' walk to the SAN ANTONIO METRO Station and METROMALL. We offer tours to San Blas - Tours to Monkey Island and the Panama Canal to help you make the most of your trip. Our home is Your home in Panama 🇵🇦
Popular amenities for Panama City house rentals
House rentals with a pool

Capira Lidice 3 bedroom house with BBQ area

The Waterfall House

Casa Rouge by SS• Unique Stay w/ pool Near PTY

Escape to Cerro Azul • Fireplace + Fire Pit + Pool

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

Oceanfront views/access w/ Pool, Privacy & Space

Your country house, Menus de la Montaña, awaits you.

Carmen's House
Weekly house rentals

Modern house with a/c 10 mins from airport

House near the airport

Casco Viejo 02, Luxury Condo, Panama Bay.

House with spectacular city and ocean views

LovelyviewPty House 15 minutes away from the airport

Residence in Panama

Cabin in Cerro Azul with Forest View

Altos de Cerro Azul Mountain House
Private house rentals

Luxury Home with Pool in the Best Neighborhood

Country house in Altos de Cerro Azul

CASA DE LINA HOSPITALITY, TRANQUILITY AND COMFORT

Beautiful house in Brisas del Golf

House with Private Pool and two parking spaces

Furnished house near Tocumen Airport.

The Bird's Nest - Cerro Azul

Cozy House, Beautiful Garden, Altos de Cerro Azul
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