
House vacation rentals in Panama City
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Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

Cantabria House - 10 minutes from the Airport
Spacious and comfortable home just 10 minutes from Tocumen Airport and only 200 meters from the Metro. Perfect for families, groups, or business trips. Fast 500 Mbps Wi-Fi, 3 bedrooms, 2 full bathrooms, fully equipped kitchen, air conditioning throughout the house, cable TV, patio with outdoor furniture, private parking, and self check-in. Long layover, family trip, or work in the city? This home has it all: comfort, location, and privacy. Book now and feel at home from the very first moment!

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Apartamento Lilia Airport 1
"Experimenta una estancia cómoda y conveniente en nuestro acogedor apartamento, ubicado a solo 10 minutos del aeropuerto Tocumen. Equipado con todas las comodidades necesarias para tu descanso, desde conexión WiFi hasta una cocina equipada, este espacio te ofrece la oportunidad de relajarte y recargar energías. Disfruta del confort del aire acondicionado, agua caliente/fria en el baño, una cama y sofá cama para tu comodidad, televisión con cable , y toallas y sobrecama para tu conveniencia.

Casco Viejo 02, Luxury Condo, Panama Bay.
DIRECT VIEW ONTO PANAMA CANAL. Washer/Dryer Direct Ocean View : Direct Ocean views off all rooms. Ships transit the canal! Swimming Pool, Beach, Fitness Center: Casco Viejo (Historical City) History , Restaurants, Nightlife, Music, Top Tourist sights. Stunning Views, Panama Bay: , Ultra Modern Accommodation, ON Cinto Costera (Ocean Walk) . Marina, Adjacent to Casco, watch the Panama Life unfold: Main City Seafood 37 Restaurants, all FRESH Seafood. AC's in all rooms.

Large Private Residence in an Excellent Area
House in the best areas of the country. Very quiet street, downtown, near restaurants, pharmacies, malls among others. Large comfortable residence for groups or families. Private parking for up to 2 cars 4 Spacious bedrooms, 2 comfortable studios, living room, breakfast room, large terrace. *Opcion Kosher Disponible* House in one of the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall and more. Large comfortable residence for groups.

Charming House in Casco Viejo
This recently renovated house is an absolute treasure. It blends history, charm, and modern comfort. Archeologists uncovered artifacts dating to the seventeenth century. Tastefully furnished with modern comforts and antiques, it's steps away from the Panama Canal Museum and in the heart of Casco Viejo, perfect for guests looking to immerse themselves in the cultural and culinary delights before retreating to the comfort and tranquility of their temporary home.

Beautiful spacious full apartment near Albrook
Spacious and cozy apartment in a very quiet area surrounded by nature. The apartment is complete, everything is ready to welcome you. All services are included. Close to the Miraflores locks, the City of Knowledge, the Metropolitan National Park, Cerro Ancón, and the Albrook Terminal. Close to the Los Rios pool. Accessibility for buses and taxi. For security reasons, cameras at the main entrance, terrace and patio. No cameras in indoor spaces.

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Casa Santa by SS • 3BR Perfect Stay Near City
This memorable place is anything but ordinary. This stylish place is perfect for group of persons or family trips. Conveniently located next to shopping malls and supermarkets you’re literally minutes from the train station and just minutes to the city. San Antonio is a safe place for families. Enjoy a cozy silent place with everything you can need for your stay.
Popular amenities for Panama City house rentals
House rentals with a pool

Luxury Home with Pool in the Best Neighborhood

A beautiful apartment with a swimming pool, BBQ area, and gym

Nice duplex house with a swimming pool.

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

House of the waterfalls

Airbnb - Vacation

On the beach, entire apartment, panoramic terrace and more

Large Downtown Panama City Villa with Private Pool
Weekly house rentals

Modern and minimalist Altos de Cerro Azul

A complete and cozy house near Tocumen Airport

LovelyviewPty House 15 minutes away from the airport

Cabin in Cerro Azul with Forest View

Casa de Montaña Altos de Cerro Azul

My Blue Escape

Luxury house in Cerro Azul

Spacious & cozy 4 bedroom home.
Private house rentals

An amazing apartment with a private terrace

Country house in Altos de Cerro Azul

house 2 bedrooms, 2, kitchen, dining room, in ancon

A nice house equipped for rest or home office

Specious house that can accommodate up to seven

Family House | 4 floors | BBQ | 20 Pax | Views

House with spectacular city and ocean views

Residence in Panama
Quick stats about house rentals in Panama City

Total vacation rentals
Explore 470 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at ﺩ.ﺇ37 per night before taxes and fees

Verified guest reviews
Over 7,270 verified reviews to help you choose

Family-friendly vacation rentals
180 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 160 rentals that welcome pets

Vacation rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
220 properties have a dedicated workspace

Wi-Fi availability
430 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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