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House vacation rentals in Panama City

Find and book unique houses on Airbnb

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Popular amenities for Panama City house rentals

House rentals with a pool

Guest favorite
Home in Veracruz
5 out of 5 average rating, 7 reviews

Luxury beachfront villa!

ShamirRating, 5 stars1 month ago
The host was great. Rafael, the co-host helped with things we needed and accommodations were made to help us enjoy our stay.
Home in pacifico
4.75 out of 5 average rating, 4 reviews

Luxury Home with Pool in the Best Neighborhood

TreRating, 5 stars1 month ago
Good stay, would stay again if I come back. Scott y Diana are very helpful. both respond in Spanish and English. Mario is also very helpful. I appreciate all the help provided for making the stay nice and easy.
Home in Panamá
4.53 out of 5 average rating, 38 reviews

A beautiful apartment with a swimming pool, BBQ area, and gym

ManuelaRating, 5 stars2 months ago
Hi Andres! We wanted to thank you from the bottom of our hearts for making our stay in Panama so special. From the first moment you were incredibly attentive, friendly and helpful. We really appreciate your willingness to help us, your recommendations and even offering to accompany us, that says a lot about the quality of person you are. The apartment exceeded our expectations: a spectacular view, impeccable, comfortable and with everything you need to feel at home. It was definitely a 10/10 experience. We're leaving happy, with very nice memories, and you were a big part of that. Thank you for everything! We hope to be back soon
Guest favorite
Home in Panama City
4.95 out of 5 average rating, 40 reviews

Nice duplex house with a swimming pool.

MaricelRating, 5 stars2 weeks ago
Don Gerardo was an amazing host. He picked my family and I up from the airport and welcomed us to his place with a cake which he did not need to do at all. He went above and beyond by offering us advice on local spots and attractions and completely changing the washing machine when the last one had issues. He was very attentive and welcoming to my elderly parents. He even drove my daughter back home from the airport after dropping her off there (one hour round trip) as she had forgotten something important at his place. The house was huge and exactly what my family and I needed. There were no issues at all from the house apart from the aforementioned washing machine which he rectified immediately when we were out of the house. Would definitely recommend to anyone with a big family to stay in Gerardo’s place. He is just an amazing guy and super super host . Highly recommended
Superhost
Home in Panamá
4.75 out of 5 average rating, 8 reviews

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

MaurisnelRating, 5 stars2 months ago
Mrs. Helen is very attentive, kind and cordial! We had an excellent weekend, it is a perfect place to rest and get out of everyday life, there you find everything you need to have a good time! Clean and cozy place, and above all very safe!
Superhost
Home in Panamá
5 out of 5 average rating, 3 reviews

Airbnb - Tropical Vacation!

EduardRating, 5 stars3 months ago
Mike exceeded our expectations making our stay very comfortable. Nice pool! Safe neighborhood!
Superhost
Home in Panamá
4.71 out of 5 average rating, 24 reviews

Your country house, Menus de la Montaña, awaits you.

KennyRating, 5 stars2 weeks ago
Excellent Host and excellent place to stay at Panamas Beautiful Mountains, a place to relax with family and friends. Excellent Spot! Nos vemos pronto Pablo Saludos!!
Superhost
Home in Panamá
4.65 out of 5 average rating, 49 reviews

Modern Stay in Albrook - 10 min to City

ChristineRating, 5 stars5 months ago
beautiful neighborhood and interesting house. The outdoors was so beautiful. we love the pool. The kitchen was good for cooking which we did. Love having AC in the common room. which was really nice for chilling. Beds were comfortable. if you're a light sleeper, dogs might wake you in the night like they did us. especially if you're in the master bedroom or the basement. there was no hot water in three of the four bedrooms but astonish did try unsuccessfully to get it fixed. I would still recommend it.

Weekly house rentals

Home in Vacamonte
4.75 out of 5 average rating, 4 reviews

Nice whole house for rent

WilliamRating, 5 stars14 months ago
Paulette was an amazing host! We rented her place for three months, but her plans changed due to some family event, so we stayed there only one month. That wasn’t a big problem for us, we rented an amazing place at Casa Bonita, Playa Bonita. So, everything worked out perfectly. The most importing is Paulette’s professionalism and personality. On our arrival there was a nice bottle of red wine and a toy for our dog and a nice greeting card. Our dog absolutely loved the toy. Thank you Paulette!
Home in Vacamonte
4.89 out of 5 average rating, 19 reviews

Cozy beach house near the city!

LuzRating, 5 stars16 months ago
We had a great time, we really liked it. The house is very nice and spacious, it matches the description. The beach is nice and we have fun at the pool. There are sidewalks and parks nearby for hiking.
Home in Panamá
4.62 out of 5 average rating, 61 reviews

Modern and minimalist Altos de Cerro Azul

AbelRating, 5 stars8 months ago
Excellent cabin to spend time connected with nature and disconnected from the hustle and bustle of the city Also excellent Jeanette service. Very pending to give immediate response. 100% recommended
Home in Panamá
4.71 out of 5 average rating, 7 reviews

Country house in Altos de Cerro Azul

FlorRating, 5 stars7 months ago
I went with my family and we had a great time. Our host was attentive with all the instructions for both check-in and check-out. The weather in the residence is super nice, the rooms are spacious, bathrooms are clean and tidy. The kitchen has utilities to cook and also on the patio utilería para Asados. The internet worked great for us. The area where the house is located, has a security gate for access. Cristóbal recommended us various activities near the area such as hikes, swimming pool, among others. He was always in touch kindly and quickly. We hope to return.
Home in Panamá
5 out of 5 average rating, 4 reviews

A nice house equipped for rest or home office

LydiaRating, 5 stars23 months ago
Super attentive host. I work on resolving needs such as transfer, I provide contacts for home delivery, always very attentive and friendly
Home in Panamá Oeste
5 out of 5 average rating, 6 reviews

Specious house that can accommodate up to seven

KarlaRating, 5 stars77 months ago
We loved it, excellent place, a very safe and quiet residential space, bathrooms, luxury room... Seriously, highly recommended for family, business trip, studio, tourism, etc. Adriano was very attentive and helpful from day one. Thank you for everything.
Home in Panamá
4.83 out of 5 average rating, 6 reviews

Beautiful house in Brisas del Golf

ReynaldoRating, 5 stars15 months ago
Ana Carolina's house is beautiful, very well-equipped and in an excellent location very close to shopping malls, restaurants, shops, bus stop. The neighborhood is very quiet with security officers in the booth. You also have access to a very nice and clean pool. The attention of Ana Carolina's parents was exceptional, very kind, attentive to our questions and requests. I would definitely stay here again.
Home in Panamá
4.77 out of 5 average rating, 13 reviews

Beautiful Studio Apartment

AadilRating, 5 stars1 month ago
very clean and private also walking distance from groceries and bakery. Will definitely book here again next visit to panama

Private house rentals

Home in Panamá
4.75 out of 5 average rating, 4 reviews

Bruno's House

DanRating, 5 stars12 months ago
Diener was extremely responsive to any questions I had and very accommodating to my extra request. I have already reserved my next stay with him for my next trip to Panama City.
Home in Panamá

Family-Friendly Panama Canal Home with Fenced Yard

NicoldRating, 5 stars1 month ago
Quiet atmosphere, you feel at home, very welcoming, quiet... Peace within the busy city...
Home in San Miguelito

House near the airport

JhousueRating, 5 stars11 months ago
Something else is really nice
Home in Panamá

The Bird's Nest - Cerro Azul

KathiaRating, 5 stars5 months ago
We stayed at Bird’s Nest in Cerro Azul for two nights with our family, and it was truly incredible. This place exceeded all our expectations—it’s even better than the photos! The view is stunning, offering spectacular sunsets that will take your breath away. It was a refreshing change for us to head to the mountains instead of the beach. The setting is peaceful, surrounded by nature, and we saw so many beautiful birds we had never seen before. The house has its own unique charm. The beds are incredibly comfortable, and the host was amazing, ensuring everything was perfect for our stay. They’ve thought of every detail, from a fully stocked kitchen with everything you need to make a barbecue, to great coffee and filtered water. There’s no TV, but the Wi-Fi is excellent, and we had so much fun playing games. Their selection of table games and the ping-pong table kept us entertained all evening. Even the rain added to the cozy atmosphere.If you’re looking for a peaceful getaway by nature
Home in Panamá
4.38 out of 5 average rating, 8 reviews

An oasis in the middle of the city

PauloRating, 5 stars3 months ago
Very friendly open space
Home in Panamá
New place to stay

La Casa del Capitán

AntoniaRating, 5 stars2 weeks ago
This location is 3 levels of absolute bliss! The photos do not do the home any justice. From top to bottom it is gorgeous, whimsical and romantic. The host and family were responsive, helpful and made me feel right at home. I would not hesitate to recommend a stay at this location
Home in Brisas del Golf

Hello Panama! Brisas del Golf

AdonaisRating, 5 stars2 months ago
Great neighborhood. Lovely decorations & the host was very responsive. I will definitely book again!
Home in Arraiján

Beachfront house 30 minutes from the city

JoseRating, 5 stars3 months ago
Very cozy place, good privacy, highly recommended

Quick stats about house rentals in Panama City

  • Total rentals

    450 properties

  • Nightly prices starting at

    ﺩ.ﺇ37 before taxes and fees

  • Total number of reviews

    6.1K reviews

  • Family-friendly rentals

    160 properties are a good fit for families

  • Pet-friendly rentals

    140 properties allow pets

  • Rentals with a pool

    90 properties have a pool

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panamá Province
  4. Panama City
  5. House rentals