
Vacation rentals in Panamá Province
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Panamá Province
Guests agree: these stays are highly rated for location, cleanliness, and more.

A warm and cozy flat in Casco Viejo
Enjoy a unique stay in this apartment, a historic Casco Viejo building that once served as one of the area’s early bakeries in the 19th century. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Panoramic Casco Viejo Lookout in The Sands
exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Espectacular ático Duplex en Panamá Casco antiguo, de 265 M2 con balcones, terrazas privadas exterior, cuenta con una salón jardín interior, un comedor, 3 hab. (+ sofá cama en studio), recientemente reformado con concepto Loft, diseño exclusivo único y confortable, en la mejor zona del Casco viejo, perfecto para relajarse y desconectar, cocina , lavavajilla, sala con lavadora. piscina compartida, asc, portero 24-7, no se permiten niños que no sepan nadar, gran variedad de ocio en la zona.

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Amazing experience in Casco Viejo historical site1
Disfruta la cultura panameña desde el centro de Casco Viejo, donde conocerás la arquitectura colonial, podrás visitar los mejores restaurantes, sitios nocturnos y rooftops característicos de la zona. Apartamento tranquilo y confortable. Cuenta con una cama queen, 1.5 baños, armario, aire acondicionado, cocina equipada, comedor, sala, acceso a WiFi de 500 mbps, espacio de trabajo, balcón y comedor al aire libre. ¡Te ofrecemos todo lo que necesitas para vivir la mejor experiencia local!

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Walk to Everything | Luxury Stay in Casco Viej
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Casco Antiguo Apartment with Balcony & Stone Wall
Elegante apartamento en el corazón de Casco Antiguo. Disfruta de un espacio colonial con paredes de piedra expuesta, iluminación cálida y un encantador balcón con vista a calles vibrantes. Ubicado en Avenida B, a pasos de restaurantes, cafeterías, rooftop bars y lugares históricos. Capacidad para hasta 5 huéspedes. Perfecto para vivir la cultura y energía de Casco Viejo. Debido al ambiente animado del área, puede escucharse ruido nocturno los fines de semana.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
Popular amenities for Panamá Province vacation rentals
Other great vacation rentals in Panamá Province

Pelicans's View, Seafront Apartment, private pool

Luxury beachfront villa!

Loft in Casco Antiguo, Joya Colonial

Old Town & Ocean View

Signature Luxury Residence w/ Balcony + Terrace

Luxury apt in Panama City 2 Rooms 3 Baths

The Crystal House: Luxury Modern Wood Cabin

Tropicool Casco Loft w/King Bed & Rooftop
Destinations to explore
- Rentals with a kayak Panamá Province
- Condo rentals Panamá Province
- Rentals with a fire pit Panamá Province
- Pet-friendly rentals Panamá Province
- Townhouse rentals Panamá Province
- Rentals with beach access Panamá Province
- Guesthouse rentals Panamá Province
- Rentals with a sauna Panamá Province
- Private suite rentals Panamá Province
- Rentals with a home theater Panamá Province
- Family-friendly rentals Panamá Province
- Rentals with breakfast Panamá Province
- Hostel rentals Panamá Province
- Serviced apartment rentals Panamá Province
- Rentals with an EV charger Panamá Province
- Smoking-friendly rentals Panamá Province
- Bed and breakfasts Panamá Province
- Boat rentals Panamá Province
- Apartment rentals Panamá Province
- Vacation home rentals Panamá Province
- Nature eco lodge rentals Panamá Province
- Rentals with an accessible height bed Panamá Province
- Tiny house rentals Panamá Province
- Boutique hotels Panamá Province
- Rentals with a patio Panamá Province
- Waterfront rentals Panamá Province
- Beachfront rentals Panamá Province
- Loft rentals Panamá Province
- Rentals with outdoor seating Panamá Province
- Rentals with pools Panamá Province
- Villa rentals Panamá Province
- Rentals with lake access Panamá Province
- Rentals with a fireplace Panamá Province
- Hotel rooms Panamá Province
- Rentals with a hot tub Panamá Province
- Rentals with a washer and dryer Panamá Province
- House rentals Panamá Province
- Cabin rentals Panamá Province
- Fitness-friendly rentals Panamá Province
- Things to do Panamá Province
- Sports activities Panamá Province
- Nature and outdoors Panamá Province
- Tours Panamá Province
- Sightseeing Panamá Province
- Food and drink Panamá Province
- Art and culture Panamá Province
- Things to do Panama
- Art and culture Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama
- Entertainment Panama
- Food and drink Panama





