
Vacation rentals in Panamá Province
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Panamá Province
Guests agree: these stays are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Modern City Escape Nice Views & Great Location!
Modern and stylish apartment with an open layout and all the comforts of home. Sleeps up to four with a Queen bed in the bedroom and a sofa bed in the living area. Enjoy a fully equipped kitchen, high-speed-WiFi and A/C. Located in the heart of the city, just steps from the banking district and Via España, and close to Soho Mall, Multiplaza Mall, restaurants, cafes, pharmacies, and the metro. Perfect for business or leisure travelers seeking convenience, comfort, and a true City experience.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Large Apartment in La Cuadra - Casco | By Alura
El Casco Antiguo de Panamá es uno de los barrios más encantadores y vibrantes de la ciudad. Declarado Patrimonio de la Humanidad por la UNESCO. El Apartamento El espacio combina líneas modernas con detalles originales del barrio. Cuenta con una distribución luminosa, cocina equipada, sala amplia y acabados pensados para brindar comodidad. Posee un dormitorio con cama king y un hermoso balcón. Es ideal para quienes buscan vivir una experiencia auténtica en el Casco Antiguo.

Modern and cozy downtown apartment with a unique rooftop
LIVE AND ENJOY a unique experience in the heart of Panama City, modern, cozy and fully equipped apartment. Its strategic and central location will allow you to move easily and get to know THE BEST OF PANAMA. Restaurants, shopping malls, supermarkets, pharmacies, hotels and main tourist attractions, all within minutes. Ideal for tours, remote work, or short and long stays. Here you will find comfort, design, spectacular views and an unforgettable stay.

Modern and luxurious accommodation in Cinta Costera
Experience the luxurious PH Yoo overlooking the city in this elegant apartment with a king-size bed and floor-to-ceiling windows. Enjoy world-class amenities: swimming pool, gym, squash court, spa, and more. Prime location near tourist areas, restaurants, bars, and shopping malls. Inside the building there are dining options with exclusive discounts and free valet parking. Modern, spacious and sophisticated space for an unforgettable getaway.

180° Old Town Views, Pool & Coworking
☆ What our guests are saying: "The view was astonishing." "It is clean, quaint, and cozy." "I truly felt safe, and it was very modern." "No one can beat this treatment Chef kiss". ☆ Early check-in is available! AMENITIES: ☆ Salt-water pool. ☆ Comfy coworking space with free wifi. ☆ High-speed elevators. ☆ Bicycle rental is available in the lobby. ☆ Parking space (extra fee applies). ☆ Lobby concierge and 24/7 security.

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

King Bed, Creative Design Steps from Casco Viejo
Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Ocean View on Avenida Balboa
Enjoy breathtaking views, a spectacular oceanfront infinity pool, and direct access to the Poin Panama resort, as well as a variety of dining and bar options for an unparalleled vacation experience. This spacious and cozy apartment is ideal for families, couples or travelers looking for an unforgettable getaway. Book now and start your adventure in this urban oasis!

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM
Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA
Popular amenities for Panamá Province vacation rentals
Other great vacation rentals in Panamá Province

Yoo Panama - Luxurious and Modern

Modern Sky Studio with a View of the Panama Bay

Cozy Studio in Cinta Costera with Home Vibes

Luxury apartment in the heart of Panama

Apartment in Historic Center

The Don Quixote Loft by AcoModo (Ocean View)

Minimalist 1br with Modern Decor

Bright 1BR•Pool, Gym•Near 50th Street
Destinations to explore
- Rentals with an EV charger Panamá Province
- Rentals with a kayak Panamá Province
- Pet-friendly rentals Panamá Province
- Nature eco lodge rentals Panamá Province
- Loft rentals Panamá Province
- Hotel rooms Panamá Province
- Rentals with a fireplace Panamá Province
- Ski-in/ski-out rentals Panamá Province
- Rentals with beach access Panamá Province
- Guesthouse rentals Panamá Province
- Rentals with a home theater Panamá Province
- Tiny house rentals Panamá Province
- Fitness-friendly rentals Panamá Province
- Villa rentals Panamá Province
- Family-friendly rentals Panamá Province
- House rentals Panamá Province
- Rentals with a washer and dryer Panamá Province
- Beachfront rentals Panamá Province
- Boat rentals Panamá Province
- Apartment rentals Panamá Province
- Private suite rentals Panamá Province
- Rentals with an accessible height bed Panamá Province
- Serviced apartment rentals Panamá Province
- Condo rentals Panamá Province
- Rentals with a fire pit Panamá Province
- Townhouse rentals Panamá Province
- Waterfront rentals Panamá Province
- Boutique hotels Panamá Province
- Rentals with a patio Panamá Province
- Rentals with a sauna Panamá Province
- Cabin rentals Panamá Province
- Rentals with breakfast Panamá Province
- Rentals with outdoor seating Panamá Province
- Rentals with pools Panamá Province
- Hostel rentals Panamá Province
- Rentals with a hot tub Panamá Province
- Rentals with lake access Panamá Province
- Bed and breakfasts Panamá Province
- Vacation home rentals Panamá Province
- Smoking-friendly rentals Panamá Province
- Things to do Panamá Province
- Food and drink Panamá Province
- Sports activities Panamá Province
- Art and culture Panamá Province
- Sightseeing Panamá Province
- Nature and outdoors Panamá Province
- Tours Panamá Province
- Things to do Panama
- Sightseeing Panama
- Sports activities Panama
- Tours Panama
- Art and culture Panama
- Entertainment Panama
- Nature and outdoors Panama
- Food and drink Panama




