
Vacation rentals in Panama
Book unique homes, vacation rentals, and more on Airbnb
Top-rated vacation rentals in Panama
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama vacation rentals
Homes in Panama

La Casita Barrbra B&B
We loved the Casita, it was clean, updated and well stocked. Our greeting was wonderful, we were welcomed 'home', introduced to the common area and staff. They have a Stocked bar fridge that you are welcomed to, you simply jot down what beverage you took and you can pay at checkout. Super convenient. However, due to this they do not like/allow outside alcohol even in your private Casita. The Casita is within a bunch of other residences, tho its at the end of a long dock, so you get somewhat the feeling of privacy as long as you don't look around too much lol. As you come to the BNB it is quite dirty, garbage everywhere, dog poo, garbage floating in the water. Breakfast is available before 9.30am, unfortunately we didn't take advantage of this, but we were warmly welcomed to. The people here are truly so incredible! We loved our short stay, people are wonderful, it is close to town and the view is amazing. We would stay again if privacy is not a concern.

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath
Great stay. The place was as described and the views were just amazing! Living right on the beach - great. There are some restaurants nearby (e.g. Surf Shack) with top dishes, cocktails and absolutely friendly staff. It was a wonderful stay and the reliable and extremely friendly communication with the host also contributed to this. We will be happy to come back!

New house, fenced, quiet and safe environment.
Juan and Bianka have such a cute house. We enjoyed every moment we spent there and they were always so responsive. I would definitely recommend. Really close to Penonome.

Puntita Manzanillo, fantastic sea and jungle
Excellent stay again in this amazing place. Thanks for having us, as always.

Casa Pelicano - Tropical house w pool and seaview
Feels like a private 5 star hotel. Truly amazing and perfect place

3 min to Pedasi, 5 min to the Beach, Private Pool!
Great house and friendly host. The beds were super comfy, the showers had plenty of pressure and hot water, the internet was very fast and reliable. As possibly expected the power went out once during our week long stay and Ian helped us to notify the petty company and get them to come out to fix it right away. The house was very nicely decorated and its location was perfectly halfway between Playa Arenal and Pedasí center of town. The pool and garden were nice too. And there were two TVs what worked well too. The kitchen had all the basics for cooking and cleaning and a pretty good setup for most everyone too.!I’ve been to Pedasí a few times before and this place is definitely the best value for a smaller group, especially with dogs, and for those reasons alone we’ll definitely try to return. Thanks so much for hosting us.

Casa Clearwater... Your Caribbean Dream
We had a fantastic time ! We will be back

Bocas Sunset Beach House
The photos do not do this beautiful house justice. It is gorgeous and beautifully decorated and kept. The views are incredible, lots of extras like kayaks, snorkels and masks, and fresh eggs from the chickens on the property! Don't think about it, book it!
Apartments in Panama

Cozy apartment near Casco Viejo
I loved that it has amenities that other Airbnbs don't have, such as an iron and hair dryer, and she was also attentive when answering.

Cozy 2 Bedroom w/ Splash Pool
I think our stay here was one of best stays with Airbnb of all time. The location in Casco Viejo was great for walking or a short Uber ride and we felt completely safe our whole stay. This apartment is beautiful and was very well equipped and had everything to make our stay great! The rooftop patio and plunge pool were great for relaxing after a long day of sight seeing. We would stay here again in a heartbeat!

Luxury apt in Panama City 2 Rooms 3 Baths
Gabriela's apartment is beautiful. The building is secure. I really enjoyed my stay in the beautiful and very comfortable apartment. I highly recommend staying here.

Sky Lounge/ APT vista al Mar, Pool bar & GYM!
Cesar was a great host — extremely responsive. The apartment had an excellent view and was close enough to walk or Uber to several attractions, such as the Panama Canal, Casco Viejo, and the causeway.

Superb Apartment In The Center Of Panama City
We loved staying at this location! Juan was very friendly and responsive. The apartment had everything that we needed. The room was spacious, and the bed was excellent —very cozy!

Mola Studio | By Paradox
I really enjoyed staying here wish I could have stayed longer but I will be back.

The Captain's Canal View Penthouse
Lovely condo in a tourist area. Nice views of the bay and the canal. Linens were nice and place was clean. We even have free coffee

Buenaventura Golf & Beach Resort Lux Apartment
Amazing condo, had everything we needed, great communication with hosts, they even left a crib ready for our toddler. Hope to be back one day, thank you for everything!
Pet-friendly vacation rentals in Panama

CasaMonèt
good location near great restaurants and supermarket pretty garden sitting area

Jane’s Treehouse~ Charming 1bed/1bath treehouse
If you are looking to spend a few days away from everything and surrounded by nature, this would be your option. Stephanie is super helpful and whenever you call or write to her, she will be there for you. She is definitely an excellent host. The tree house is spectacular, perfect for recharging and filling you with a lot of peace. The hacienda is large enough for you to walk around and discover its different attractions.

Panoramic Views Pacific to Baru, Boquete District
If you are looking for a modern, clean, functional casita in an absolutely tranquil and relaxing spot…..This is it! Wake up to the sounds of beautiful birds every morning. Open the curtains to see the lush flora and fauna of the stunning property. Enjoy a cup of local coffee (provided by the host) on the lower patio for views of the Pacific Ocean, Vulcan Baru and the town of Boquete below. Nothing more peaceful than the serene air of the cloud forest. All or your worries and woes will melt away. Although you might not want to leave the property, you are only a short drive from all that Boquete has to offer. The host, Sherry and Troy are wonderful. They are very helpful and informative. Anything you may need they will assist. This is a five star experience. Highly recommend by my wife and I. We cannot stop thinking about it since we have arrived back home.

Carenero Hills 3 - Beach & Surf Bungalows.
I recommend 100% ! Nestled in the jungle, this is the perfect place to relax and not too far from restaurants. It’s the perfect deal for what we needed, which is rest ! We also loved the recommendations that Steve gave us and mostly loved our private boat tour to la isla escudo de veraguas, which looks unreal because of how beautiful this place is. The place was spotless, well cleaned and we couldn’t have wished for better. We will be back !

Little House in the Jungle
Very close to Boquete main road while still being high enough in the mountain to have tranquility. The place felt safe, warm and welcoming. All of this for a very good price, I loved my stay here! Thank you Holly.

Casitas in Butterfly and Honey Farm
We feel so lucky to have found this Airbnb listing for our time in Boquete. We loved Boquete of course. But staying here was a destination in and of itself. The farm is beautiful, gardens and birds and butterflies. And we loved learning about the bees and the butterflies. The room was perfect, just as it appears. Very clean. The staff were so accommodating. Highly recommend! Easy access to town by calling a taxi or walking although that takes about 20 mins.

Nice house with pool steps to the beach
It was an excellent stay. Very kind, the interior of the house is perfect, the pool is very nice. We went to work in Capira and this place was our resting place for those 2 days, it was perfect.

Beautiful annex in canal house steps from Canal.
Everything's great! 100% recommended. Super comfortable arrival, the accommodation is in a beautiful setting, everything is very comfortable.
Your guide to Panama
All About Panama
A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.
The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.
The best time to stay in a vacation rental in Panama
The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.
Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.
Top things to do in Panama
Casco Viejo
As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.
Panama Canal
When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.
Bocas Del Toro
Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.
Destinations to explore
- Pet-friendly rentals Panama
- Boutique hotel rentals Panama
- Rentals with a patio Panama
- Condo rentals Panama
- Chalet rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Fitness-friendly rentals Panama
- Cottage rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Boat rentals Panama
- Bed and breakfasts Panama
- Rentals with beach access Panama
- Family-friendly rentals Panama
- Lakehouse rentals Panama
- Beach house rentals Panama
- Island rentals Panama
- Villa rentals Panama
- Nature eco lodge rentals Panama
- Rentals with lake access Panama
- Rentals with pools Panama
- Smoking-friendly rentals Panama
- Hotel rentals Panama
- Loft rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Rentals with an accessible height bed Panama
- Waterfront rentals Panama
- Beach condo rentals Panama
- Kid-friendly rentals Panama
- Bungalow rentals Panama
- Apartment rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with a sauna Panama
- Townhouse rentals Panama
- Treehouse rentals Panama
- House rentals Panama
- Rentals with a hot tub Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with breakfast Panama
- Rentals with a home theater Panama
- Rentals with a fire pit Panama
- Rentals with a fireplace Panama
- Tiny house rentals Panama
- Farmstay rentals Panama
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom