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Vacation rentals in Panama

Book unique homes, vacation rentals, and more on Airbnb

Top-rated vacation rentals in Panama

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Rental unit in Panamá
Cozy apartment with amazing views
Apartamento de más de 120 m2, luminoso, totalmente equipado, con terraza, internet de alta velocidad, aire acondicionado en salón y dormitorio, 2 TVs, lavaplatos y todo lo que puedas necesitar Disfruta de las mejores vistas de la ciudad en uno de los edificios más modernos de Panamá, con piscina, gym, 3 restaurantes, supermarket, seguridad 24/7 y más Gracias a la ubicación céntrica de este alojamiento, tú y los tuyos lo tendréis todo a mano y disfrutaréis de las mejores vistas al océano
ﺩ.ﺇ367 per night
Rental unit in Panamá
Design Pool and 180º Rooftop N2
**Update: Newly renovated with anti-noise windows for a perfect rest** Apartment recently renovated and decorated by an international designer, on the main avenue of Casco Viejo (nocturnal silence area) with views of the church and the most beautiful existing ruins. In addition to a 180º rooftop with an infinity pool. One bedroom apartment with double queen bed, living room, dining room, kitchen, beautiful bathroom, 55" Smart Tv, private balcony with views of the Church, etc.
ﺩ.ﺇ357 per night
Rental unit in Panamá
Design studio with pool, rooftop and colonial pati
Boutique Hotel Casa Marichu, located in the heart of the Old Town, recently renovated and restored while maintaining the colonial essence and adding all the amenities for a spectacular stay. It consists of 10 boutique rooms, a patio with gardening and a beautiful fountain, a relaxation reception area, and an incredible rooftop with views of the Old Town and a spectacular unique swimming pool in Panama.
ﺩ.ﺇ430 per night

Beach house rentals in Panama

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Home in Bocas del Toro District
Orange House - Over The Water Rentals
ﺩ.ﺇ478 per night
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Home in Colón Island
Very Nice One bedroom Apartment over the Caribbean
ﺩ.ﺇ383 per night
Private room in Santa Catalina
COIBAHOUSE BEACHFRONT GUESTHOUSE-ROOM 2
ﺩ.ﺇ257 per night
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Home in Playa Venao
Directly on Playa Venao, sleeps 8-10+
ﺩ.ﺇ1,414 per night

Panama beach vacation rentals

Rental unit in Panamá
Cozy Ocean Front Apt With Infinity Pool
ﺩ.ﺇ239 per night
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Rental unit in Panamá
Tropicool Loft w/rooftop steps from Casco
ﺩ.ﺇ327 per night
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Rental unit in Panamá
Modern condo with ocean view and hanging chair
ﺩ.ﺇ239 per night
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Rental unit in Nueva Gorgona
Beach paradise for two people
ﺩ.ﺇ184 per night

House rentals in Panama

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Home in Panamá
Spacious accommodation with ocean views
ﺩ.ﺇ378 per night
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Private room in Panamá
Small & cozy Albrook room with private bathroom
ﺩ.ﺇ92 per night
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Home in Altos del Maria
Modern House in Altos del Maria, Panama
ﺩ.ﺇ996 per night
Private room in Panamá
Casa Díaz: Independent cozy room in Cerro Ancón.
ﺩ.ﺇ162 per night

Your guide to Panama

All About Panama

A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.

The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.


The best time to stay in a vacation rental in Panama

The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.

Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.


Top things to do in Panama

Casco Viejo

As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.

Panama Canal

When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.

Bocas Del Toro

Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.

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