Boutique hotel vacation rentals in Panama
Find and book unique boutique hotel rentals on Airbnb
Top-rated boutique hotel rentals in Panama
Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama boutique hotel rentals
Family-friendly boutique hotels rentals
Boutique hotel in Boquete
4.76 out of 5 average rating, 58 reviewsCabañas Villa San Miguel #5 / Boquete.
Feb 20 – 27
Boutique hotel in Punta Chame
5.0 out of 5 average rating, 7 reviewsPink Palace Panama
Oct 4 – 11
Hotel room in Puerto Armuelles
4.53 out of 5 average rating, 19 reviewsBeachfront Ocean Suite with Swiming Pool
May 6 – 13
Boutique hotel in Copecito
4.77 out of 5 average rating, 30 reviewsB&B Cabanas los hummingbirds
Oct 15 – 22
Boutique hotel in isla contadora.
4.75 out of 5 average rating, 8 reviewsBeautiful B&B with unbeatable customer care!!!
Feb 17 – 24
Boutique hotel in Portobelo
Beachfront Boutique Hotel and Restaurant Portobelo
Sep 26 – Oct 3
Boutique hotel in Soná
5.0 out of 5 average rating, 5 reviewsVilla Coco Twin Room
Jan 25 – Feb 1
Boutique hotel in Soná
Villa Coco Jungle Villa
Sep 21 – 28
Boutique hotels rentals with a patio
Boutique hotel in Bocas del Toro
4.71 out of 5 average rating, 17 reviewsOver the Sea Turtle Mini Cabin with Veranda
May 31 – Jun 7
Boutique hotel in San Carlos
5.0 out of 5 average rating, 3 reviewsLa Maracuyá Panama_ splendid large Room in Nature
Aug 18 – 25
Boutique hotel in Lagartero
4.7 out of 5 average rating, 10 reviewsCharming 1-Bedroom Beachfront Hotel With Pool
Apr 11 – 18
Boutique hotel in Soná District
4.5 out of 5 average rating, 6 reviewsGarden View Double Bedroom at Nativo
Nov 15 – 22
Boutique hotel in Pedasi
4.83 out of 5 average rating, 12 reviewsRoom in Boutique Hostel; Private Bathroom
Apr 11 – 18
Boutique hotel in Panamá
Eshel Panama Suites, Atlantic suite 04
Jan 18 – 25
Boutique hotel in Panamá
Charming Hotel in Casco Viejo Corner Suite
Jul 8 – 15
Boutique hotel in Panamá
Beautiful Private Apartment in Old Town
Oct 28 – Nov 4
Monthly boutique hotels rentals
Boutique hotel in El Valle de Antón
4.56 out of 5 average rating, 96 reviewsHOSTAL EL MAJO DEL VALLE II
Aug 26 – Sep 23
Shared hotel room in Bocas del Toro
Selina Bocas del Toro - Bed in Small Dorm
Aug 8 – Sep 5
Boutique hotel in Panamá
Hotel san Roque
May 4 – Jun 1
Boutique hotel in David
Near bus station and downtown in David, Chiriqui
Apr 18 – May 16
Boutique hotel in Bocas del Toro
4.19 out of 5 average rating, 16 reviewsPrivate Double Room With Private Bathroom A/C WiFi
Dec 14 – Jan 11
Shared hotel room in Bastimentos Island
Selina Bocas del Toro Red Frog - Bed in Small Dorm
Sep 16 – Oct 14
Boutique hotel in El Valle de Antón
4.4 out of 5 average rating, 20 reviewsHOSTAL EL MAJO DEL VALLE
Dec 5 – Jan 2
Shared hotel room in Bocas del Toro
4.29 out of 5 average rating, 14 reviewsSelina Bocas del Toro - Bed in Large Dorm
Sep 23 – Oct 21
Destinations to explore
- Rentals with a washer and dryer Panama
- Rentals with beach access Panama
- Family-friendly rentals Panama
- Vacation home rentals Panama
- Apartment rentals Panama
- Townhouse rentals Panama
- Condo rentals Panama
- Cabin rentals Panama
- Wheelchair accessible rentals Panama
- Beach house rentals Panama
- Bungalow rentals Panama
- Hotel rentals Panama
- Pet-friendly rentals Panama
- Guesthouse rentals Panama
- Rentals with a fireplace Panama
- Chalet rentals Panama
- Rentals with a patio Panama
- Treehouse rentals Panama
- Rentals with breakfast Panama
- Boat rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Waterfront rentals Panama
- House rentals Panama
- Rentals with outdoor seating Panama
- Tiny house rentals Panama
- Monthly Rentals Panama
- Nature eco lodge rentals Panama
- Smoking-friendly rentals Panama
- Rentals with pools Panama
- Rentals with a home theater Panama
- Serviced apartment rentals Panama
- Cottage rentals Panama
- Loft rentals Panama
- Beach condo rentals Panama
- Farmstay rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with a hot tub Panama
- Rentals with a sauna Panama
- Kid-friendly rentals Panama
- Fitness-friendly rentals Panama
- Rentals with a fire pit Panama
- Rentals with an accessible height bed Panama
- Beachfront rentals Panama
- Rentals with lake access Panama
- Rentals with a kayak Panama
- Villa rentals Panama
- Mansion rentals Panama
- Island rentals Panama
- Bed and breakfasts Panama
- Hotel rentals Panama City
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom