Boutique hotels in Panama

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Panama

Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

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Superhost

A furnished bedroom features a spacious bed with white linens, flanked by bedside tables with lamps. Soft artwork adorns the wall above, while a bench rests at the foot of the bed. A cozy throw drapes over the bench, completing the inviting arrangement.

Hotel room in Boquete

4.89 out of 5 average rating, 117 reviews

Villa Alejandro - Tastefully Furnished Room

Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Guest favorite

An outdoor pool is illuminated in a calming blue hue, surrounded by lounge chairs. Umbrellas provide shade, while plants add a touch of greenery. The night sky and distant hills create a serene backdrop, enhancing the tranquil atmosphere of the space.

Hotel room in Taboga Island

5.0 out of 5 average rating, 11 reviews

Taboga Palace Hotel. Beach front English Bouquet

Shush,, Its a Secret Paradise, a beach front location, and surrounded with different restaurants and fondas, Friendly staff, English and Spanish spoken . , Why not spoil yourself once in your life, come stay in our Palace , you come to us and you wont want to leave. The Island is safe, the people friendly and welcoming. Hiking, Kayaking, Snorkeling, fishing, Swimming, Come explore the Island of Flowers, Or just chill out. Specialty of the house are Daves , Strong Margaritas .

Superhost

A spacious bed is positioned centrally in the room, adorned with neutral-toned bedding. Two ottoman-like stools are placed at the foot of the bed. A laptop is being used on the bed, with soft lighting emanating from lamps on either side, creating a cozy ambiance.

Hotel room in San Carlos District

4.78 out of 5 average rating, 141 reviews

Surf, Beach & Relax Boutique Stay I Manglar Lodge

Manglar Lodge is a relaxed boutique beach stay in the surf town of El Palmar, San Carlos, on Panama’s Pacific coast. Surrounded by tropical gardens, it’s the perfect place to unwind and enjoy the laid-back beach vibe. This king room includes Wi-Fi, A/C, cable TV, private bathroom, mini fridge, microwave, coffee maker, and a cozy atmosphere for a comfortable stay. Just a short walk to the beach, surf spots, restaurants, and local cafés. **Upper floor room, stairs required. **No pets allowed.

Superhost

A spacious living area is furnished with woven seating and a glass coffee table. Large windows offer views of the sea, while a desk and flat-screen TV are visible. A kitchenette with modern appliances complements the inviting space, enhanced by natural light.

Hotel room in Isla Colón

4.86 out of 5 average rating, 28 reviews

Hotel Palma Royale - 1 bedroom suite w/ kitchen

Luxury suite with separate bedroom with queen size bed, kitchen, and living area, balcony with spectacular sea views, bathroom with rain water shower, office desk, air conditioning, coffee pot with grinder and panamanian coffee beans, flat screen tv with cable, upper floors, free wifi, large quality windows and doors, pillow top mattresses, marble or coral tile, bamboo flooring, non-smoking rooms, beach towels, umbrellas, blow dryers, laundry service, board games.

Guest favorite

A rustic wooden bungalow stands elevated among lush tropical foliage, featuring a private plunge pool surrounded by sun loungers. Large windows with turquoise drapes provide a view of the evening sky, while steps lead to the entrance of the cozy retreat.

Hotel room in Bastimentos

4.95 out of 5 average rating, 55 reviews

The Firefly oceanfront casita w/ pool Adults only

Our b&b is a little off the beaten path but we love it that way. Listing is for one of our two private, oceanfront bungalows. We can let you know which one is available at time of booking. We are an eco lodge & describe our vibe as "hip, rustic beach house". Our rooms are fan cooled & have in room safes. Pool is shared by all five rooms. Breakfast is included. If a "resort" or 4 star place is your vibe, we are probably not for you :) We accept guests 15 and up.

Guest favorite

The room features two spacious beds with modern wooden frames. A wooden bench runs along the foot of one bed. A large area rug adds a pop of color to the floor. Soft lighting complements the earthy tones of the walls.

Hotel room in Playa Venao

5.0 out of 5 average rating, 17 reviews

Brisa - Ocean Views, Calm Vibes, King/Twin beds

Brisa is the perfect family room on the ground floor, made for relaxing after a fun day in the sun. Equipped with a mini fridge, AC, TV (ready for you to sign into all your online viewing accounts), hot/cold water and beautiful breezy covered seating area outside with ocean views. Steps from our pool! *Additional guest, available to kids up to 12 year old* *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host. *

Guest favorite

Aerial view of the lush surroundings featuring a mix of vibrant green foliage and the tranquil Caribbean Sea. Solar panels are visible among the trees, emphasizing eco-friendliness. Several buildings are scattered throughout the landscape, highlighting the natural integration of the property within its jungle setting.

Hotel room in Bastimentos

5.0 out of 5 average rating, 31 reviews

Amanecer : Delicious Included Breakfast

Amanecer is our sunrise apartment. The space is immersed in the jungle with an ocean view. This two room, 3 person apartment has memory foam bedding, strong wifi, and stunning views. This apartment is a great choice for a family or group of friends. Two bedrooms with a bathroom in the middle. Enjoy new yoga shala, snorkeling our private reef, & FREE local organic breakfast served in our over the water eatery, Juntos.

Guest favorite

A charming stone structure is surrounded by lush greenery in this tranquil setting. Soft lighting enhances the architectural details, while the inviting garden area features neatly trimmed hedges and flower beds. A patio area can be seen beside the main building, perfect for outdoor relaxation.

Hotel room in El Valle de Antón

4.84 out of 5 average rating, 51 reviews

Suite medievale natura & arte

La Corte del Re é una struttura turistica composta da un insieme di suite con tematica medievale (arte macabra) immerse nel bosco dove arte e natura si fondono nel cuore del Valle di Anton. A pochi passi dal centro sono dotate di tutti i confort e contano con un parco, piscina, lago con carpe Koi e parcheggio. Non dispongono di una cucina. Gli ospiti possono usufruire di una accademia di Muay Thai, jiu-jitsu e MMA.

Guest favorite

A close-up view of vibrant purple bougainvillea flowers is presented alongside a well-maintained pathway, leading to a charming building with arched windows and a wooden front door. Green foliage frames the entrance, enhancing the welcoming atmosphere.

Hotel room in Bethania

4.87 out of 5 average rating, 46 reviews

Habitaciones privadas Sofia's B&B Hostal Boutique

Alojamiento tipo hostal boutique, contamos con 7 cómodas habitaciones privadas con baño, para una capacidad total de 18 huéspedes. La tarifa mostrada por Airbnb para tu reserva distribuye 2 huéspedes por habitación, es decir, los huéspedes deberan compartir camas y/o habitaciones. Si requieres una distribución especial de habitaciones para tu grupo, contacta primero con el anfitrión, ya que la tarifa podría variar.

Top guest favorite

Large green doors open to a charming balcony, revealing a view of a red-tiled roof and a small table with two chairs. A soft sofa is positioned nearby, complementing the inviting atmosphere of the space.

Hotel room in San Felipe

4.87 out of 5 average rating, 156 reviews

Corcho rooms #2 - king room with balconies

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Guest favorite

A room featuring a wooden bunk bed and a spacious bed against a wall, with light blue walls enhancing the interior. A bathroom entrance is visible, and a small window allows natural light to enter. Soft furnishings include a blanket and towels placed on the beds.

Hotel room in Bocas del Toro Province

4.72 out of 5 average rating, 69 reviews

Surfari Bocas Quadruple Room #24

Surfari Bocas is close to restaurants and dining, nightlife, family-friendly activities, the airport, water-taxis, and great views. You’ll love Surfari because of its proximity to everything, the ambiance, . My place is good for couples, solo adventurers, business travelers, and families. The rates are room only.

Guest favorite

A bright blue room features a queen bed with a patterned bedspread and two pillows. A small wooden table and chair are visible, while colorful fish art adorns the walls. A door leads to the bathroom, and a window allows natural light into the space.

Hotel room in Las Tablas Abajo

4.81 out of 5 average rating, 90 reviews

Blue Room for 2 at Casa Lassini - Oceanfront!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.