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Hotel vacation rentals in Panama

Find and book unique hotel rentals on Airbnb

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Popular amenities for Panama hotel rentals

Family-friendly hotel rentals

A sleeping area features a spacious bed adorned with a blue and white floral patterned blanket. A decorative mirror hangs above the bed, reflecting light. A bedside table with a lamp stands next to the bed, and dark curtains frame a glass door.
Hotel room in isla contadora.
4.75 out of 5 average rating, 8 reviews

Beautiful B&B with unbeatable customer care!!!

Alma RosaRating, 5 stars36 months ago
The beach is very close by walking, but in the heat it is difficult to walk long distances. It is considerable to rent a cart early to ensure availability
A wooden sign displays the text 'Tanti Familiar' in elegant script, surrounded by delicate white flowers. The natural grain of the wood is visible, contributing to a warm and inviting look.
Private room in Punta Chame
4.8 out of 5 average rating, 51 reviews

Tanti 2, room in house on beachfront terrain

CatherineRating, 5 stars27 months ago
I highly recommend you to spend your vacation there. Francisco is an extraordinary welcome! We have dinner with him and his family. People with a big heart!! The beach and on-site facilities are worth a visit. The only negative point ( said with lots of love ) is that when booking we can't choose the room and the number of people. I could just book for one person. I was told that there would be an extra charge for the 2nd person. (my friend) At the end of my stay, I was charged double the price. I admit to being surprised and paying 2 x the price to be 2 in the room instead of one person. I may have had to inquire about the extra price when booking because it changes a hotel room budget… All of you, Francisco, and the people who work for him, of exceptional kindness:)
A wooden cabana sits elevated on stilts, topped with a thatched roof. Steps lead up to the open side, revealing a cozy interior. Surrounding foliage includes a variety of trees and plants, contributing to the natural setting of the community.
Nature lodge in Darién Province
4.7 out of 5 average rating, 20 reviews

La Chunga

KristýnaRating, 5 stars3 months ago
Accommodation in La Chunga was an experience. Everyone was very friendly, the nature is beautiful, 10/10 ❤️ Thank you K + M 🇨🇿
Hotel room in San Carlos
4.78 out of 5 average rating, 125 reviews

B) Beach, surf and Relax with King size bed

RodolfoRating, 5 stars3 weeks ago
totally worth it. Staff and surroundings are great. Beach was awesome and only few steps away.
A view of the property’s landscaped garden leads to the beach, with sandy ground and palm trees swaying in the breeze. A patio with seating is visible, while the ocean stretches out in the background, framed by lush greenery and a clear sky.
Hotel room in Punta Chame
5 out of 5 average rating, 9 reviews

Pink Palace Panama

AlejandroRating, 5 stars10 months ago
Great experience at Peggy's place, a top-notch hostess! Sweet, attentive and very helpful. Important that they know that they have 3 dogs, they are very friendly. The house is facing the sea, just steps walking to the shore.
Top guest favorite
A serene river flows gently surrounded by lush greenery and trees. Smooth rocks are partially submerged in the water, creating a tranquil natural setting. Clear reflections of the surrounding foliage can be seen on the surface, enhancing the peaceful ambiance of the area.
Private room in Panamá
4.99 out of 5 average rating, 102 reviews

Casa Momote Loma Limon

KarenRating, 5 stars2 weeks ago
It is the perfect spot for disconnecting, bird watching and baking. Mariel and her husband are extremely friendly and you feel welcome. They have 3 very friendly dogs and a quiet kitten. There is a river very close to the house, 2 minutes by car. It's so close to Panama City that I'm sure I'll be back ♥️
Top guest favorite
A private dock extends over the water, featuring two lounge chairs positioned for relaxation. A potted plant adds a touch of greenery. The scenery presents a clear view of the water and distant land under a bright blue sky.
Casa particular in Bocas del Toro
4.96 out of 5 average rating, 95 reviews

Urania House

MadisonRating, 5 stars3 weeks ago
We loved staying on Saigon Bay, away from the busy parts of Bocas Town but also a walkable distance. Great home base to explore Bocas Del Toro from.
A three-story building is surrounded by greenery, featuring balconies with chairs and hammocks. A stone well sits in the foreground, and outdoor pathways are lined with plants. The structure's white walls are complemented by wooden accents, creating a welcoming atmosphere.
Hotel room in PA
4.66 out of 5 average rating, 68 reviews

double room, island counter

IngridRating, 5 stars2 weeks ago
We enjoyed our stay. The staff is always welcoming and super friendly. The service and the Food is delicious. We have stayed at Geralds mutiple times and we always enjoy it!

Hotel rentals with a pool

Guest favorite
Hotel room in La Enea
4.74 out of 5 average rating, 43 reviews

Private, open concept room with pool/beach access!

Luis AntonioRating, 5 stars3 weeks ago
Very good stay, it is the second time I am, very clean and pleasant, by car everything 15 or 20 minutes away, the environment of nature is excellent and the restaurant with very good attention, modest but good tasting, I hope to return soon. Slds
Guest favorite
Private room in Panamá
4.82 out of 5 average rating, 22 reviews

Desk & Dream Room

YateRating, 5 stars2 days ago
Eduardo is really excellent. A helpful, attentive host with the best directions to guide you if you're not from Panama! I loved the room, the apartment is very cozy and you can breathe in peace and cleanliness. Highly recommended 100%
Guest favorite
A view of a large, inviting swimming pool is framed by tall palm trees, with vibrant green foliage surrounding the area. The pool's bright blue water is clearly visible, reflecting sunlight under a clear sky.
Hotel room in Coclé Province
4.89 out of 5 average rating, 9 reviews

SUITE 2 floors crowned luxuryclub

JuanRating, 5 stars3 months ago
Very good stay and the host was always kind and attentive to us
Superhost
The room features a spacious bed and a bunk bed, both adorned with red bedding. A wooden dresser sits against the wall, and natural light floods in through a large window that offers a view of the pool area.
Private room in Soná District
4.86 out of 5 average rating, 7 reviews

SkyRoom - Private Room with Shared Bathroom

OliviaRating, 5 stars10 months ago
We loved staying at Catalina Cabins! Just a 10 min walk from town and the beach, it was super convenient while also very quiet and peaceful. Juan was a great host!
A small sleeping area features light green walls and a cozy bed with a striped linen cover. A single window is partially draped with green curtains, allowing natural light to illuminate a potted plant positioned on the windowsill.
Private room in Panama City
4.88 out of 5 average rating, 8 reviews

El Tornillo semi-private space.

KendraRating, 5 stars3 weeks ago
The pool and breakfast are a huge bonus for this place. I was in the semi-private room, you can still hear people on the other side, but it was so much better than being in a dorm as I could get changed and leave my stuff out without any concern. They also provided me with a lock for my door because I didn’t have one. Definitely worth it for the price. I also walked around at night after meeting people at a bar and felt very safe in this neighborhood.
An infinity pool stretches towards the horizon, offering unobstructed views of rolling hills and a serene landscape bathed in soft sunset hues. The smooth water appears to merge with the sky, while a stone patio surrounds the pool area, enhancing the tranquil setting.
Hotel room in Campana
4.6 out of 5 average rating, 15 reviews

Queen Room3 at Vida Lotus Retreat & Spa, Limon, PA

JorgeRating, 5 stars1 week ago
Very nice place, with a good view, Michael was very kind with his attention, the dogs were very friendly, the place in general is very quiet and surrounded by nature. Please note that the food is vegan. The breakfast pancakes were very good.
Superhost
A tranquil pool area is framed by lush greenery, featuring sleek lounge chairs positioned along the water's edge. Natural light filters through the leaves, creating a serene atmosphere, while the clear blue water reflects the surrounding foliage.
Hotel room in Playa Coronado
5 out of 5 average rating, 3 reviews

Pacific Suite: Relaxing Getaway with Pool

John WilmerRating, 5 stars1 week ago
Comfortable rooms, spectacular breakfast, A1 pools. I loved it, I'll be back soon? Definitely.
Superhost
Private room in Playa Venao
5 out of 5 average rating, 4 reviews

Dos Mares Venao Village - Bungalow

KristinaRating, 5 stars3 months ago
Excellent stay. Private and quiet oasis, perfect for families who want to be close to venao but not in it. The staff was very kind and the facilities were beautiful! Comfortable bed, lots of towels, delicious coffee. Perfect stay!!

Hotel rentals with a patio

The image captures a view of a charming building with a white façade and a tower, framed by lush palm trees. A landscaped pathway with neatly trimmed hedges and decorative planters leads toward the street, where lampposts line the cobblestone path under a partly cloudy sky.
Private room in Macaracas
5 out of 5 average rating, 7 reviews

Charming hostel with a private balcony

Erick AdolfoRating, 5 stars3 months ago
I made the reservation for my parents and they had a great time, congratulations to the owner for the treatment, the ease of communication, for also accepting the conditions of the customers👏🏽. Great, Congratulations
Superhost
A comfortable sleeping area features a double bed with a soft, neutral-colored blanket. Two abstract paintings adorn the walls, and natural light enters through a shaded window. A wooden cabinet and a small bedside table provide functional space.
Private room in Alto Boquete
4.67 out of 5 average rating, 6 reviews

Cozy private room with bathroom in Alto Boquete

Dayro AlexanderRating, 5 stars2 months ago
A room with an accessible location just minutes from downtown Boquete. We were missing a few things and they resolved it for us instantly. A quiet area and everything was very clean and tidy
Top guest favorite
A double bed with crisp white linens is positioned against a light-colored wall. Air conditioning is mounted above, providing comfort. A handmade garment rack is visible to the side, along with a decorative piece and a doorway leading outside.
Private room in Santa Catalina
4.95 out of 5 average rating, 20 reviews

Casa Manila Doble Room with terrace

CarolinRating, 5 stars3 weeks ago
Enrique and Pia were really nice and helpful! Communication was great and they were lovely hosts!
An outdoor terrace is shown with level flooring and smooth tiles, featuring a table and several chairs that overlook the ocean. The distant shoreline and calm water are visible through expansive glass doors, enhancing the connection between indoor and outdoor spaces.
Casa particular in Contadora Island
New place to stay

Ocean Front House on exclusive Contadora Island

DagmarRating, 5 stars1 week ago
My family and I stayed at this property for 3 nights. We loved it. The house was spacious and well kept. The views of the ocean from the house were spectacular, the kitchen was fully equipped with everything you needed. The communication with the owners was great. They have a person that lives on the property and takes care of the house and he was extremely kind and helpful. We will definitely stay here against
Superhost
A two-story villa is set against a clear blue sky, featuring a distinctive blue roof. Lush greenery surrounds the property, with blooming shrubs bordering a driveway. The entrance includes a covered porch with seating, inviting relaxation in the outdoor space.
Casa particular in Rio Hato
4.6 out of 5 average rating, 5 reviews

Villa in Playa Blanca Resort Rio Hato

GuiselaRating, 5 stars16 months ago
Our stay was pleasant, the beach and pool are a few minutes walk away. I allowed us to check in a little later. Communication was fluid with the host. We were a group of 9 people and we were all comfortable.
Guest favorite
A stone pathway leads downwards through lush tropical foliage towards a serene ocean view. The tranquil water reflects sunlight under a clear sky, with a wooden structure visible in the distance. The warm tones of the cottage complement the natural surroundings.
Hotel room in Boca Chica
4.89 out of 5 average rating, 9 reviews

Tranquil Ocean View Cottage At Seagull Cove Resort

HannahRating, 5 stars12 months ago
Great place to stay! The views from our room and restaurant were amazing, our room was comfortable and clean. The restaurant was really good, the breakfast selection is fresh with a different fresh juice of the day, for lunch or dinner I definitely recommend the bruschetta starter and either of the tacos. So with great location, tasty food, comfortable room my favourite part was actually the staff as they were so friendly and helpful, from the front of house to the gardener and housekeeper, they are a great team and made our stay extra special.
A spacious studio cabin features a king bed with colorful linens and a wooden bed frame. A dining table with chairs is positioned next to the window, allowing natural light to enter. Vibrant decor and large windows create a bright, inviting space.
Hotel room in Bocas del Toro
4.86 out of 5 average rating, 7 reviews

Sea View Butterfly honeymoon A/C Garden Cabin

KaitRating, 5 stars31 months ago
Our dog became very sick just before we were supposed to go on vacation at this Airbnb. Thankfully, the host was super kind and allowed us to change our stay to a new date at the very last minute for no additional charge. We appreciate the customer service level greatly!

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