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Apartment vacation rentals in Panama

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Top-rated apartment rentals in Panama

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
Apartment in Panamá
4.94 out of 5 average rating, 109 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Superhost
Apartment in Panama City
4.77 out of 5 average rating, 101 reviews

Apartment in the Causeway Amador

Olvídate de las preocupaciones en este gran alojamiento ¡es un oasis de tranquilidad! Donde podrás disfrutar de las vistas al canal de Panamá y ver los barcos que por ahí transitan,un espacio lleno de comodidades con una ubicación perfecta, puedes caminar por las calles del Causeway, visitar el museo de la Biodiversidad, restaurantes de diversas especialidades, parque de diversiones, paseos en bici etc, todo combina para hacer de estas vacaciones una experiencia inolvidable para toda tu familia

Top guest favorite
A comfortable seating area features a wooden couch adorned with light-colored pillows. Large windows provide a view of the lush greenery outside, while a warm light fixture adds a soft glow to the room. The space is complemented by a simple wooden table and concrete flooring.
Apartment in Provincia de Veraguas
4.94 out of 5 average rating, 125 reviews

Casa Melina Torio Cozy upscale 2b jungle apartment

Stylish jungle two bedroom apartment near all major Torio attractions: waterfall, jungle trails, Torio River, Playa Torio & Morrillo Surf break. The apartment is fully equipped with everything you need & want (Hot water, AC, WiFi & TV). Perfect for a couple/family seeking to blend work and play. Casa Melina was designed so our guests can fully experience our Torio culture. Cook with local fresh ingredients, discover Torio on foot & return to rest in the coziest rental you have ever experienced.

Guest favorite
A spacious outdoor area features wooden dining tables surrounded by potted plants. The space includes a plunge pool, comfortable seating, and a hammock for relaxation, with views of the nearby structures and the sky above.
Apartment in Panamá
4.87 out of 5 average rating, 376 reviews

Casco Viejo 360° View Old Tower Penthouse

Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Guest favorite
Apartment in Coronado
4.86 out of 5 average rating, 105 reviews

Beachfront 2BR, Amazing Terrace, Jacuzzi and Views

Enjoy beautiful sunsets and the relaxing sound of the waves from your private terrace—the largest in Coronado Bay. This spacious apartment features 2 TVs and 3 AC units across the bedrooms, living, and dining areas. The main bedroom has a comfortable king bed, and the second bedroom offers one and one full bes. The fully equipped kitchen includes a stove, refrigerator, coffee maker, toaster, kettle, appliances, and a dining set for four. Comfortable, practical, and designed for a great stay.

Guest favorite
A spacious master bedroom features a king-size bed with a soft grey comforter. Two elegant benches are positioned at the foot of the bed. A ceiling fan distributes air throughout the room, while light fixtures provide a warm glow. An open layout leads to a dressing area and private bathroom.
Apartment in Panamá
4.83 out of 5 average rating, 176 reviews

Lovely Spacious 3BR in Casco Viejo w/Balcony

Welcome to Casa Bandera, your retreat in the heart of Casco Viejo! Located in Panama's iconic Casco Antiguo, this elegant apartment combines the area's historic charm with modern comfort. It features three cozy bedrooms, each with a private bathroom; an in-house laundry center, a fully equipped kitchen, a living room, and a dining room, perfect for sharing in an exclusive setting. Perfect for up to six people. Enjoy an unforgettable stay in a cozy and fully equipped environment.

Guest favorite
A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.
Apartment in Juan Gallego
4.87 out of 5 average rating, 147 reviews

Pebos Reef Apt 2 · Beachfront · Sea View Terrace

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Guest favorite
A historic building with a prominent tower features elegant architecture, complemented by lush greenery in the foreground. Nearby palms and flowering trees create a serene environment, while the sky offers soft blue tones, enhancing the overall ambiance of the vibrant Casco Antiguo area.
Apartment in Panama City
4.85 out of 5 average rating, 117 reviews

Best Location-Fancy Apartment in CascoViejo

Experience absolute luxury in our fully remodeled loft, with access to a 360° rooftop, where you'll enjoy the best views of the city. The building features an elevator for your convenience. Located right in front of a plaza with renowned restaurants, the location is unbeatable, and security is guaranteed. Live an exceptional experience in Panama’s Casco Antiguo! Book now and immerse yourself in the luxury, perfect location, and amazing views that our apartment has to offer!

Guest favorite
An open living space features a large gray sectional sofa paired with a round wooden coffee table. A patterned rug lies beneath, complementing the light wooden flooring. The kitchen area is visible in the background, showcasing modern appliances and a breakfast bar with stools.
Apartment in Panamá
4.94 out of 5 average rating, 171 reviews

Cozy 2 Bedroom w/ Splash Pool

Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

Top guest favorite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in Panamá
4.98 out of 5 average rating, 171 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top guest favorite
Apartment in Panama City
4.97 out of 5 average rating, 101 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Guest favorite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Apartment in Panama City
4.91 out of 5 average rating, 102 reviews

The best view of the Old Town

Welcome to this charming accommodation located in the heart of Casco Viejo, in front of one of the most emblematic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

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