Vacation home rentals in Panama

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Panama

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Superhost

Vacation home in Panamá

4.95 out of 5 average rating, 74 reviews

Beautiful apartment in the old town with balcony!

Enjoy a stylish and relaxing experience in this very centrally located and quiet accommodation. The apartment is equipped with everything necessary for 4 people. It is situated on the western edge of the beautifully renovated and colorful old town of Panama (Casco Viejo), right next to the church and the main square of Santa Ana. From here you can reach all the highlights of the old town, as well as the lively and multifaceted Av. Central, or the coastal promenade "Cinta Costera". BIENVENIDO a Panamá!

Mar 13 – 20

ﺩ.ﺇ221 per night

Guest favorite

Vacation home in Bocas del Toro

5.0 out of 5 average rating, 44 reviews

The Pool House Too, Beach House on Paunch Beach

The Pool House Too is a gorgeous one bedroom hideaway steps from the beach at Paunch, one of Bocas' most beautiful surf beaches. The house has a private plunge pool within lush tropical gardens, a comfortable lounge, a fully equipped kitchen, both en-suite bathroom and guest half bathroom, and a covered outside lounge/dining area. There is a washer and dryer, private covered parking and good WiFi. The bedroom is air conditioned. There are 7 restaurants/cafes within walking distance of the house.

Jan 18 – 25

ﺩ.ﺇ661 per night

Superhost

Vacation home in Bocas del Toro Province

4.84 out of 5 average rating, 19 reviews

Beautiful 2 bedroom open air home jungle home

Enjoy the wonder of nature in this jungle home that is perfect for the adventurer at heart. The house is tucked into the jungle and its gardens are the home to sloths, monkeys and other wildlife. Feel more connected to nature in this off grid home. It’s powered by the sun and the natural environment. It’s a short walk to beautiful sand filled beaches. You can hear the ocean and the world around you at all times through the year. Bluff beach is minutes away and home to world class surfing.

Oct 14 – 21

ﺩ.ﺇ385 per night

Guest favorite

Vacation home in Panama City

5.0 out of 5 average rating, 30 reviews

Luxury Apartment With Private Beach And Sea View

Apartment with stunning beach and sea views The resort is surrounded by a beautiful rainforest and natural wildlife. It is a unique tropical oasis with beachfront condominiums adjacent to a neighboring five-star hotel.The Playa Bonita Village resort is located amidst a beautiful rainforest and natural wildlife on an exclusive private beach, adjacent to the Westin Hotel and is just 15 minutes from the city. The resort enjoys beautiful views of the rainforest and the Pacific Ocean.

Jan 18 – 25

ﺩ.ﺇ566 per night

Superhost

Vacation home in Juan Gallego

4.84 out of 5 average rating, 80 reviews

Pebos Reef, 12 guests, Amazing views!!

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Oct 11 – 18

ﺩ.ﺇ1,131 per night

Guest favorite

Vacation home in Playa Los Destiladeros

4.95 out of 5 average rating, 20 reviews

Curcu House: magical beach house & tropical forest

Curcu-House is a cozy bioclimatic house with tropical architecture, with a steel structure, teak walls and floors, and large translucent doors with views of the sea and the exuberant vegetation. Large flying terraces that touch the treetops, with an open concept, allowing us to connect with nature and with oneself. The lot where the property is located has a great diversity of fruit trees, lianas, and birds that come to drink and lull us to sleep with their songs.

Sep 6 – 13

ﺩ.ﺇ577 per night

Guest favorite

Vacation home in Bocas del Toro

4.92 out of 5 average rating, 24 reviews

Jungle house under the giants at the Bluff Beach

NEW OPENING: October 2022 Enjoy your vacation in the rustic jungle house as a nature and beach lover directly under rainforest giants. The cottage sleeps 4 pers in 2 bedrooms, with outdoor kitchen on the covered terrace and an outdoor bathroom with warm rainforest shower, wooden bathtub with whirlpool and double sinks. Experience the jungle up close with exotic birds, howler monkeys, sloths and ocean sounds. Only 2 minutes/200m from the mile long sandy beach.

Feb 1 – 8

ﺩ.ﺇ440 per night

Guest favorite

Vacation home in Bocas del Toro

4.97 out of 5 average rating, 29 reviews

VISTA DEL MAR @ Casa Rosada Feel the Breeze....

STUNNING OCEAN VIEW HOME IN PLAYA PAUNCH! A Surfer's Dream - Tiger Tail is Right Outside your Front Door. Dynamic Ocean Views from the Comfort of your Private Terrace. Entertaining Monkey Antics are Enjoyable from the Rear, Jungle View Entrance. 10 minutes from Town and Steps Away from Great Surfing, Gorgeous Wading Pools, Snorkeling, Diving & 6 Great Dining Options. A Comfortable Place to Launch All Your Adventures or Just Sit and Enjoy The Lush Scenery.

Jun 10 – 17

ﺩ.ﺇ456 per night

Guest favorite

Vacation home in Maria Chiquita

4.95 out of 5 average rating, 73 reviews

**Playa Escondida - Paradise in the caribbean sea

Playa Escondida is a jewel in the Caribbean with white sand and surrounded by turquoise water and full of green. The apartment is super comfy, with all amenities for a perfect stay. The condo counts with a great infrastructure, including a restobar, a shawarma grill, sushi bar and a convenience store. There is a wonderful swimming pool; 2 lagoons suitable for swimming; a football (5p) court; gym and plenty of space for you to walk along safe and sound.

Jul 7 – 14

ﺩ.ﺇ1,018 per night

Superhost

Vacation home in Panamá

4.8 out of 5 average rating, 50 reviews

Modern Apartment with pool in Casco Viejo

The apartment is located on the first floor, letter K, and has 3 balconies. It is modern and central, in the old town of Panama City, close to restaurants, museums and nightlife. It has everything you need in crockery for 8 people, and in the kitchen, you will find everything to make delicious menus!!!!! It also has laundry, ironing board and iron. We have 2 TVs, and super fast Wi-Fi, 1000 megabytes, so you can connect your favorite app!!!

Dec 18 – 25

ﺩ.ﺇ599 per night

Guest favorite

Vacation home in Panamá

4.79 out of 5 average rating, 52 reviews

Brand new apartment on Calle 50 w/Cinta Costera

This place has a strategic location: it will be very easy to plan your visit!, easy access to the metro station (3 min ) and bus stop right in front, you can visit the old town of Panama ( 10 min ), the coastal ribbon ( 5 min), and architectures such as the Tornillo, W and shopping centers very close by. You will be very close to the possibility of visiting exceptional bars, casinos, nightclubs and restaurants.

Jan 26 – Feb 2

ﺩ.ﺇ386 per night

Guest favorite

Vacation home in Maria Chiquita

5.0 out of 5 average rating, 14 reviews

Playa Escondida, Ocean View

Relax with the whole family in this quiet place to stay. Enjoy the EXCLUSIVITY that our residences offer you and the common areas of this paradise place... Playa Caribeña, no waves and flat (perfect for small children), sand in Las Bahamas and with the greatest safety and cleanliness you deserve. Don't miss the chance to have your favorite moonlit drink by the beach (near the reflectors).

Sep 21 – 28

ﺩ.ﺇ1,437 per night