
Villa vacation rentals in Panama City
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Top-rated villa rentals in Panama City
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City villa rentals
Private villa rentals

Beautiful House in Panama w/ King Beds + Pool
We stayed at Jonathan’s place for 5 nights. We were group of 8 friends. The place is right in downtown next to everything and it was easy to get around. Secure gates, walk to groceries, cafe and restaurants. Ample parking and huge refreshments and sofas for all of us. We would highly recommend this place

Villa La Vista-Panama's majestic mountain hideaway
This house is an absolute dream! It’s spacious and well-appointed, and the views are simply breathtaking! Do not hesitate to make your reservation here- I am already dreaming of the time when I can return! Jenny was incredibly helpful and super quick to respond- we were well cared for, which let us relax and enjoy ourselves even more- thank you Jenny!

In the Last Place in the World (6 guests)
A place and a house that would unquestionably come back and recommend. The house is cozy, the weather is perfect, the divine pool... in the end what it takes to spend a few days totally relaxed.

Villa Helena Studio 1 Apt Cerro Azul
Very Very super great host will fully recommend 💯 percent great location nice clean surroundings lovely pool ,beautiful scenery thank you ms Helen for taking care of me and my wife looking forward to doing it again you are a wonderful person keep up the good work 👏 🙌

Villa Helena 2 Bedrooms Cerro Azul
The stay was nothing but awesome, Ms Helen energy is absolutely amazing and her place outstanding, would definitely recommend , I felt right at home, I would definitely come back

Breathtaking Views Mansion w/King Beds
Great place. My kids enjoyed the pool, theater and pool table. I enjoyed the BBQ and the views

Tranquility and peace connect with Nature 🌤
We felt right at home. And Juan Pablo the best always attentive and very thoughtful with everything. We will definitely be back The house is highly organized and clean. I recommend the full to spend their family days and with friends. They will want to stay many more days like us. I repeat it, we will definitely be back

5BR House in Panama City w/ Pool & King Beds
Our stay at this villa in Panama was absolutely amazing! The property was beautiful and had everything we needed—from spacious rooms to a stunning backyard and pool area where our group loved hanging out. It truly felt like our own private oasis right in the heart of the city. The location was perfect—super central and just minutes away from both Casco Viejo and the newer parts of the city. We were surrounded by great restaurants, bars, and cafes, most within walking distance or a quick 5-minute drive. What really made the experience exceptional was the hospitality. Jonathan and his team were outstanding—so responsive, helpful, and accommodating. When we had a small issue with the AC in the upstairs hallway, Jonathan showed up within minutes and had a repair technician there right away. The level of service was truly impressive. I would 100% recommend staying at this villa, and I’d book any property hosted by Jonathan and his team without hesitation. They made our trip so memorable!
Villa rentals with a pool

Beautiful House in Panama w/ King Beds + Pool
We stayed at Jonathan’s place for 5 nights. We were group of 8 friends. The place is right in downtown next to everything and it was easy to get around. Secure gates, walk to groceries, cafe and restaurants. Ample parking and huge refreshments and sofas for all of us. We would highly recommend this place

Villa La Vista-Panama's majestic mountain hideaway
This house is an absolute dream! It’s spacious and well-appointed, and the views are simply breathtaking! Do not hesitate to make your reservation here- I am already dreaming of the time when I can return! Jenny was incredibly helpful and super quick to respond- we were well cared for, which let us relax and enjoy ourselves even more- thank you Jenny!

In the Last Place in the World (6 guests)
A place and a house that would unquestionably come back and recommend. The house is cozy, the weather is perfect, the divine pool... in the end what it takes to spend a few days totally relaxed.

Villa Helena Studio 1 Apt Cerro Azul
Very Very super great host will fully recommend 💯 percent great location nice clean surroundings lovely pool ,beautiful scenery thank you ms Helen for taking care of me and my wife looking forward to doing it again you are a wonderful person keep up the good work 👏 🙌

Villa Helena 2 Bedrooms Cerro Azul
The stay was nothing but awesome, Ms Helen energy is absolutely amazing and her place outstanding, would definitely recommend , I felt right at home, I would definitely come back

Breathtaking Views Mansion w/King Beds
Great place. My kids enjoyed the pool, theater and pool table. I enjoyed the BBQ and the views

5BR House in Panama City w/ Pool & King Beds
Our stay at this villa in Panama was absolutely amazing! The property was beautiful and had everything we needed—from spacious rooms to a stunning backyard and pool area where our group loved hanging out. It truly felt like our own private oasis right in the heart of the city. The location was perfect—super central and just minutes away from both Casco Viejo and the newer parts of the city. We were surrounded by great restaurants, bars, and cafes, most within walking distance or a quick 5-minute drive. What really made the experience exceptional was the hospitality. Jonathan and his team were outstanding—so responsive, helpful, and accommodating. When we had a small issue with the AC in the upstairs hallway, Jonathan showed up within minutes and had a repair technician there right away. The level of service was truly impressive. I would 100% recommend staying at this villa, and I’d book any property hosted by Jonathan and his team without hesitation. They made our trip so memorable!

Summit View Guest House Cerro Azul Panama
The experience was spectacular from start to finish. I loved the house. Our host Jenny is fantastic; she provided all the information and details The place itself is breathtaking—the house is stunning, meticulously crafted with love and attention to detail. The cleanliness of the house was impeccable, and it is equipped with everything you could possibly need for a comfortable stay. The amenities provided were top-notch, including high-speed internet and a smart TV with a variety of streaming options. The beds are exceptionally comfortable, offering a perfect night's sleep. The bathroom deserves special mention as well; it is gorgeous and spotless. The owners are great people; their genuine hospitality added a personal touch that made our stay even more memorable. I 100% recommend this beautiful place to anyone looking for a top-tier Airbnb experience that exceeds expectations. For my family, it is our new escape from the city!
Quick stats about villa rentals in Panama City
Total rentals
10 properties
Nightly prices starting at
ﺩ.ﺇ294 before taxes and fees
Total number of reviews
370 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
10 properties have a pool
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- Things to do Panama
- Nature and outdoors Panama
- Art and culture Panama
- Sightseeing Panama
- Tours Panama
- Entertainment Panama
- Food and drink Panama