
House vacation rentals in Panama City
Find and book unique houses on Airbnb
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City house rentals
House rentals with a pool

¡Villa de Lujo frente a la playa!

Luxury Home with Pool in the Best Neighborhood

Hermoso apartamento con piscina, zona BBQ, GYM

Agradable Casa Duplex con piscina.

Hermosa casa en Brisas del Golf

Villa Helena 3 Bedrms Los Altos de Cerro Azul

Airbnb - Vacation

Tu casa de campo, Menus de la Montaña, te espera.
Weekly house rentals

Family-Friendly Panama Canal Home with Fenced Yard

Moderna y minimalista Altos de Cerro Azul

Casa de campo en Altos de cerro azul

Specious house that can accommodate up to seven

Agradable casa equipada para Descanso o homeoffice

La Colina Altos de Cerro Azul

Welcome to Zola Sierra! Your Escape Into Nature.

Gorgeous Renovated Canal Home - Med or Longterm
Private house rentals

Bruno's House

Casa acogedora con jardín

Villa on the Beach, entire house

Casa de las cascadas

The Bird's Nest - Cerro Azul

CASA iluminada _312m2 + piscina armable + jardín

Acogedora y amplia casa

La Casa de Carmen
Quick stats about house rentals in Panama City
Total rentals
450 properties
Nightly prices starting at
ﺩ.ﺇ37 before taxes and fees
Total number of reviews
6.8K reviews
Family-friendly rentals
170 properties are a good fit for families
Pet-friendly rentals
140 properties allow pets
Rentals with a pool
90 properties have a pool
Destinations to explore
- Cartagena Vacation rentals
- San Andrés Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Uvita Vacation rentals
- Boquete Vacation rentals
- Coveñas Vacation rentals
- Playa Blanca Vacation rentals
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- Playa Venao Vacation rentals
- Cahuita Vacation rentals
- Villa rentals Panama City
- Rentals with pools Panama City
- Townhouse rentals Panama City
- Rentals with beach access Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Hotel rentals Panama City
- Fitness-friendly rentals Panama City
- Cabin rentals Panama City
- Rentals with lake access Panama City
- Waterfront rentals Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Rentals with a washer and dryer Panama City
- Rentals with a hot tub Panama City
- Rentals with an accessible height bed Panama City
- Rentals with a home theater Panama City
- Rentals with an EV charger Panama City
- Serviced apartment rentals Panama City
- Pet-friendly rentals Panama City
- Rentals with a sauna Panama City
- Condo rentals Panama City
- Loft rentals Panama City
- Rentals with a fire pit Panama City
- Smoking-friendly rentals Panama City
- Hostel rentals Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Guesthouse rentals Panama City
- Rentals with outdoor seating Panama City
- Rentals with breakfast Panama City
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- House rentals Panamá Province
- House rentals Panama
- Things to do Panama City
- Food and drink Panama City
- Nature and outdoors Panama City
- Art and culture Panama City
- Sports activities Panama City
- Sightseeing Panama City
- Tours Panama City
- Things to do Panamá Province
- Sightseeing Panamá Province
- Nature and outdoors Panamá Province
- Food and drink Panamá Province
- Tours Panamá Province
- Art and culture Panamá Province
- Things to do Panama
- Nature and outdoors Panama
- Food and drink Panama
- Art and culture Panama
- Entertainment Panama
- Tours Panama
- Sports activities Panama
- Sightseeing Panama