
Boutique hotels in Panama City
Find and book unique boutique hotels on Airbnb
Quick stats about boutique hotels in Panama City

Total vacation rentals
Explore 30 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at ﺩ.ﺇ 110 per night before taxes and fees

Verified guest reviews
Over 560 verified reviews to help you choose

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
30 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.6 Average rating
Panama City stays receive an average rating of 4.6 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated boutique hotels in Panama City
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Eshel Panama Suites, Atlantic suite 04
Eshel Suites, ofrece una experiencia unica para todos aquellos que deseen una estadia comoda y relajante. Diseñadas con un estilo moderno y acabados de lujo. Cada una cuenta con amplios espacios y estan decoradas con muebles de alta calidad. Los colores suaves y la iluminación cálida crean un ambiente acogedor y sofisticado. Equipadas cama queen con una marinera full, split, televisor de 43", WIFI, plancha de vapor, Caja de seguridad, miniBar, microondas, cafetera, secador y plancha de pelo.

Tropical Tranquility - Coconut Lodge
Welcome to our cozy and inviting room, perfect for relaxing or getting work done during your stay. The room is designed with a simple, yet elegant style featuring neutral tones and a refreshing green accent wall. It includes a comfortable bed and a stylish side table with a lamp for a cozy ambiance.The room is equipped with a large flat-screen TV and an efficient air conditioning system to ensure your comfort in all seasons. A small desk, making it an ideal for work or study.

Habitación Duplex Hotel Bardot Boutique
Bienvenido a Hotel Bardot Boutique, donde el lujo clásico y el diseño sofisticado se fusionan en el corazón del Casco Antiguo. Nuestra encantadora habitación de 50 m² ha sido concebida para ofrecer una experiencia íntima y acogedora para dos personas. Destaca por su cuidada estética, detalles arquitectónicos únicos y una atmósfera cálida que invita al descanso, creando un ambiente con carácter que eleva cada momento de la estancia.

Habitaciones privadas Sofia's B&B Hostal Boutique
Alojamiento tipo hostal boutique, contamos con 7 cómodas habitaciones privadas con baño, para una capacidad total de 18 huéspedes. La tarifa mostrada por Airbnb para tu reserva distribuye 2 huéspedes por habitación, es decir, los huéspedes deberan compartir camas y/o habitaciones. Si requieres una distribución especial de habitaciones para tu grupo, contacta primero con el anfitrión, ya que la tarifa podría variar.

The City Suite #208 | La Résidence Panamá
Contemporary comfort, for the modern traveler. This 43-50m² suite features 2 full beds + sofa bed, full kitchen, washer/dryer, Coffe machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With our blend of modern design, central location, and thoughtful amenities, we provide a space designed for your convenience and productivity.

Cabaña para 2 personas.
Escápate a Hacienda el Edén, Cerro Azul! 🌿 Cabaña privada para 2 personas, ideal para parejas o teletrabajo. Un refugio acogedor y sumamente cómodo rodeado de naturaleza. Disfruta de: Senderos propios, Piscina y billar, Rutas de moto y gastronomía, Fotos de fauna exótica, Te atendemos todo el día hasta que vayas a dormir. ¡El paraíso a tu alcance! ✨

Corcho rooms #2 - king room with balconies
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Suite Room in the ORHO Hotel
excellent mini apartment with the best view of the most famous building in Panama F&F Tower in the heart of the Panamà city. For information such as: transportation, transfers, tours, location, places of interest, itinerary, please consult first, since we have completely reliable, safe and economical transportation services.

Alojamiento entero Sofia's B&B Hostal Boutique
Alojamiento tipo hostal boutique, contamos con 7 cómodas habitaciones privadas con baño, para una capacidad total de 18 huéspedes. Puedes hacer uso de la cocina bien equipada, cómoda sala y comedor. Contamos con lavadora y secadora a tu disposición por un costo adicional.

The Corner Suite #110 | La Résidence Panamá
Contemporary comfort for the modern traveler. This 35–37 m² suite features a king-size bed, full kitchen, washer/dryer, Coffe machine, and A/C — designed with thoughtful touches to make you feel at home.

Beautiful loft #6 - king size and single bed
Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs.

Beautiful loft #5 - kingsize bed
Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs.
Popular amenities for Panama City boutique hotels
Family-friendly boutique hotels

Eshel Panama Suites, Union suite 03

Serenity Suite - Coconut Lodge

Eshel Panama Suites, Albany Suite 06

Beautiful loft #6 - king size and single bed

Corcho rooms #2 - king room with balconies

# Family Room (two bedroom one bath)

Beautiful loft #5 - kingsize bed

The Corner Suite #110 | La Résidence Panamá
Boutique hotels with a patio
Other boutique hotel vacation rentals

Corcho rooms #2 - king room with balconies

Beautiful loft #6 - king size and single bed

Beautiful loft #5 - kingsize bed

The Corner Suite #110 | La Résidence Panamá

# Family Room (two bedroom one bath)

Habitaciones privadas Sofia's B&B Hostal Boutique

Alojamiento entero Sofia's B&B Hostal Boutique

Charming Hotel in Casco Viejo San Felipe Jr Suite
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- Food tours Panama
- Nature and outdoors Panama
- Sports activities Panama
- Tastings Panama
- Sightseeing Panama
- Wildlife Panama
- Outdoors Panama
- Cultural tours Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama
- Cooking Panama










