Guesthouse vacation rentals in Charleston

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Popular amenities for Charleston guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
An open living space is seen with a brown leather sectional sofa adorned with colorful throw pillows. A wooden coffee table sits in front of the sofa on a blue area rug. The kitchen features white cabinetry and modern appliances, with natural light filtering through a nearby window.
Guesthouse in Charleston
4.92 out of 5 average rating, 713 reviews

Island Oasis—Near Downtown

JasonRating, 5 stars1 week ago
Apartment was very clean and great location between the beach and downtown Charleston.
Top guest favorite
A spacious bed with a soft beige headboard is centered in the image. Crisp white linens are layered with a textured throw. A bedside table, featuring a lamp and a small vase of fresh flowers, is positioned next to the bed, enhancing the calming ambiance.
Guesthouse in West Ashley
4.93 out of 5 average rating, 770 reviews

Charleston's Coolest Neighborhood

AndrewRating, 5 stars1 week ago
Stayed for an extended weekend, and it was perfect. I thoroughly enjoyed the apartment for the getaway me and my girlfriend had went on. Awesome place to visit and plenty of things to do, Brett/shannon were very helpful with recommending places to eat/activities/etc. Would 100% recommend.
Guest favorite
A well-maintained lawn features a manicured, artificial turf area leading to a charming guest house. Surrounding greenery and a path of gravel create a welcoming entry. The guest house displays a simple entrance, framed by lush foliage, contributing to a private, tranquil setting.
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 251 reviews

Bungalow Under The Oaks

CheyenneRating, 5 stars2 weeks ago
If you’re looking for a cute little place to chill for the weekend, this is a great choice! While the bungalow is a little smaller than anticipated (for 2 adults/2dogs), the fully fenced yard makes up for everything else. The yard is pretty much completely shaded by beautiful oak trees, and my dogs loved every second we spent out there. The road is busy during the day, but at night, it quiets down, and all you can hear are the cicadas.
Guest favorite
Two classic cars are parked in front of a detached garage, showcasing a vintage white convertible and a sleek gray vehicle. The garage features two closed doors, framed by light green siding and surrounded by trees, adding to the serene environment.
Guesthouse in Summerville
4.88 out of 5 average rating, 803 reviews

New Loft in Historic Summerville

AngelinaRating, 5 starstoday
Absolutely lovely. Cozy space, plenty of room for 2 people! Jacquelynn was great at responding and was very kind!
Guest favorite
A studio apartment is shown, featuring a king bed with decorative pillows and a comfortable couch. A wooden dining table and chairs are visible, alongside a chest of drawers. Natural light enters through two windows, creating a bright and inviting space.
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 255 reviews

Green Garden Studio @greengardenstudio2017

HelenRating, 5 stars4 weeks ago
This was the cutest above garage studio. It is very well done, clean and comfortable. The property is very well maintained- we would definitely stay here again! The AC was not working properly when we arrived but Holly responded immediately and got it working. Highly recommend!!
Top guest favorite
The living area is arranged with a spacious sectional sofa adorned with colorful pillows. A wooden coffee table sits in the center, complemented by a light rug. Natural light filters through the windows, illuminating the space and highlighting the rustic wooden beam above.
Guesthouse in Charleston
5 out of 5 average rating, 108 reviews

Liz Lane Cottage- entire guesthouse

KellieRating, 5 stars3 weeks ago
Beautiful accommodations, away from the hustle, but still close enough to be convenient. The home was clean and neat. We were in Charleston for a graduation, so this was a nice place to rest up and relax in between activities.
Superhost
A charming yellow cottage is framed by lush greenery, with a cozy seating area featuring bright blue chairs. A colorful hammock hangs nearby, creating an inviting space for relaxation. Sliding glass doors lead into the cottage, promoting a cheerful and welcoming atmosphere.
Guesthouse in Charleston
4.84 out of 5 average rating, 118 reviews

Romantic Beach Style Cottage close to everything!

NatalieRating, 5 stars1 month ago
Clean & conscious hosts! Mindful of needs that may crop up, lovely home & family. Flexible! Perfect oasis away from the bustle of Charleston.
Top guest favorite
A spacious bedroom features a wooden bed frame adorned with a floral-patterned comforter. Two bedside tables with lamps are positioned on either side of the bed. Bright light filters in through a window, complemented by soft neutral walls and warm wood flooring.
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 138 reviews

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!

JonathanRating, 5 stars2 weeks ago
This was our second time at Treehouse and it was just as good as the first! Katey and Jules are great hosts. The location is amazing - 10 minutes to downtown Charleston and 10 minutes to the beach. We love walking down Coleman to Shem Creek and enjoying the sights and sounds of the marsh. We love patriots point park and taking the water taxi to downtown. You won’t find a better a place for a couple getaway!

Guest house rentals with a patio

Guest favorite
The brick exterior of the guesthouse is visible, showcasing its historic charm. Lush greenery surrounds the space, with trees and plants framing the entryway. A staircase leads to the black front door, while a shaded area with an umbrella is seen in the background.
Guesthouse in Harleston Village
4.95 out of 5 average rating, 43 reviews

Secret Garden Guesthouse

MargaretRating, 5 stars1 week ago
As before, this was a peaceful, comfortable home during our stay for the Spoleto Festival in Charleston. Easy walking to performances, restaurants, and sights. Elizabeth and Jason are friendly and responsive. The lovely garden is a bonus!
Guest favorite
A modern two-story guest house is depicted, featuring a combination of white and light brown exteriors. A covered entryway with pergola extends over the front door. A tranquil pool is visible in the foreground, surrounded by landscaped greenery and stone paving.
Guesthouse in Mount Pleasant
4.96 out of 5 average rating, 131 reviews

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

GloriaRating, 5 stars2 weeks ago
My husband and I had a wonderful 5 day stay at Georgia's apartment. Georgia's attention to detail was evident in each room. The furnishings and décor brings comfort and warmth to each space. We enjoyed a lunch of bbq ribs at Saltwater Cowboys (Shem creek) while we watched dolphins swim and pelicans dive for fish. We walked off our meal while striding down the Shem Creek boardwalk. We spent 2 days at Folly beach county park, soft sand and water temperature at 77F was lovely. We took advantage of the umbrella/sand chair rental which is delivered to your chosen beach spot. Upon request, Georgia provided us with big soft beach towels. Lastly, must say Mt. Pleasant is beautiful. I ran throughout the neighborhood (in training for a marathon), each house is beautifully distinctive, folks wave, and many bits of the town's history is displayed on sign plaques throughout. It was a great vacation for us!
Top guest favorite
A bright and airy living area features a light blue sofa, accompanied by a small table and chair set. The fully equipped kitchen is visible in the background, showcasing modern appliances. Natural light floods the space through the windows, enhancing the inviting atmosphere.
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 86 reviews

Coastal Charm: Village Hideaway

AlexRating, 5 stars1 week ago
Our stay at the Village Hideaway was perfect for our family! We actually live in Mount Pleasant and had water damage in our home and were having major repairs done to our flooring. We chose Christina’s place because of the location and because for a 2 bedroom place it was very spacious. It is a beautiful and cozy house, has great appliances, and it is extremely clean and well maintained. Christina was a great host, always available when needed, and very personable. I fully recommend the Hideaway to anybody who wants to stay in a private house close to the best of Mount Pleasant and a short drive to Charleston!
Top guest favorite
A living area features two modern chairs and a round table. The light wood flooring complements the wall adorned with a floral design. A black shelving unit holds decor, and a mounted television provides entertainment, creating a stylish and inviting space.
Guesthouse in Charleston
4.95 out of 5 average rating, 122 reviews

Spacious 1 bedroom cottage in Avondale

RyanRating, 5 stars5 days ago
My partner and I really enjoyed staying at Derek and Sarah’s guest house cottage in Avondale. Even though it was located in a suburban area, we found the cottage feeling quiet and secluded once inside. The interior was cozy, the bed was comfortable, and the kitchen very usable to cook some of our meals. We drove to Charleston, and we found the parking space easy to use and clearly marked. Derek and Sarah were very friendly and responsive with any questions we had. With a car, it was an easy drive to our visit to Folly’s Beach, our carriage ride in the French Quarter, shopping at the Charleston City Market, the harbor area for our sunset cruise, the Magnolia Plantation and Gardens, the Charleston Tea Garden, and a lot more. It was a perfect launching pad for a really memorable trip.
Top guest favorite
A light-filled living area features a comfortable sectional sofa and a ceiling fan. Two windows provide natural light, while a TV is mounted on the wall. A decorative painting adds color above the sofa, and a woven area rug lies underfoot.
Guesthouse in Johns Island
4.96 out of 5 average rating, 126 reviews

Driftwood Cottage

CiannaRating, 5 stars5 days ago
Terry was very kind and a great host! The cottage is located between his house and 2 other beautiful homes. It was clean and a very cute, quaint place. Perfect for our stay.
Guest favorite
A shaded outdoor seating area is furnished with a comfortable couch and chairs, surrounded by tropical plants. A flat-screen TV is mounted on the wall, while a dining table awaits nearby. The entrance door adds a touch of charm to the inviting space.
Guesthouse in North Charleston
4.91 out of 5 average rating, 140 reviews

My Happy Place

KellyRating, 5 stars3 days ago
This was mine and my wife's first time in the Charleston area. I highly recommend this host, we have nothing but great things to say. the ability to check in early, the recommendations to food, activities and places to see, the comfort of the home and the thoughtfulness of having them leave a beautiful note and a bottle of bubbly for us due to our 8 year anniversary. I couldn't have asked for anything else. Thank you very much for everything. I would definitely stay here again.
Top guest favorite
A warm living space is highlighted by a comfortable brown sofa and accent pillows. A sleek coffee table sits on a patterned area rug, while two decorative stools provide additional seating. The bedroom area features a queen-sized bed with soft linens and bedside lamps, enhanced by natural light from nearby windows.
Guesthouse in Hanahan
4.99 out of 5 average rating, 195 reviews

The Violet Villa w/no cleaning fee

GiaRating, 5 stars1 day ago
I didn’t want to leave! The description was accurate, but this community was more adorable than we ever imagined! Absolutely awesome and convenient! The hosts went above and beyond, and I’d stay here again and again. Super affordable and definitely one of our top Air BnB experiences to date.
Guest favorite
A charming cottage is surrounded by tall trees, showcasing vibrant autumn foliage. Large glass doors provide plenty of natural light, while a small porch is visible to the side. Greenery and shrubs add to the serene outdoor setting.
Guesthouse in Johns Island
4.91 out of 5 average rating, 183 reviews

Cozy Cottage! 5 mins from Kiawah!

ReneeRating, 5 stars2 weeks ago
My husband and I thoroughly enjoyed our stay in Lucy’s super cute cottage. It was clean, well appointed, and with the perfect amount of space for a couple. Although we didn’t get a chance to try it out (a little too chilly), the outdoor bathtub was a charming feature, in addition to the other outdoor spaces available. We loved the close proximity to the beach and to downtown Charleston. We felt very comfortable and rested really well. We would absolutely come back to Lucy’s cottage, and I’m sure you will feel the same way!

Guest house rentals with a washer and dryer

Top guest favorite
A compact laundry area is equipped with a stacked washer and dryer, featuring a sleek white design. Nearby, a foldable drying rack is neatly stored against the wall, offering additional space-saving convenience.
Guesthouse in West Ashley
5 out of 5 average rating, 124 reviews

Peaceful Garden Cottage Retreat

CharlesRating, 5 stars1 month ago
This was the perfect home base for our time in Charleston. It was conveniently located, spotless, and very peaceful. So much thought went into making our stay pleasurable. Looking forward to our return trip!
Top guest favorite
A wooden walkway leads from a sandy area to the beach, bordered by native vegetation. In the distance, two individuals are seated on the sand, overlooking the ocean and a serene sky at dusk.
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 158 reviews

Beach, downtown, Alhambra Hall weddings so close!

DerekRating, 5 stars1 day ago
Our stay at Robert’s place was excellent. The neighborhood was peaceful and quiet. It was easy to get to lots of different destinations from the place. We wouldn’t hesitate to stay there again.
Guest favorite
An outdoor patio area features a square stone layout with a firepit at the center. Two wooden chairs are positioned around the firepit, and string lights provide soft illumination in the trees above. A grill is visible nearby, surrounded by greenery.
Guesthouse in West Ashley
4.9 out of 5 average rating, 623 reviews

Cozy Cottage w Games, Firepit, Grill, and More!

AshleyRating, 5 stars1 week ago
The house was adorable and very cozy! We had a wonderful stay and appreciated the snacks provided, along with the recommendations of places to go while we enjoyed our stay. Would highly recommend and would stay again if I were ever back in the area! :)
Top guest favorite
A small outdoor balcony is shown with two striped chairs positioned at a round table. A potted plant with bright pink flowers adds a pop of color to the wooden decking. Sunlight filters through greenery in the background.
Guesthouse in Charleston
5 out of 5 average rating, 260 reviews

James Island "La Casita" Nestled btw Beach & City

CallieRating, 5 stars2 weeks ago
We enjoyed our stay so much! The space was very clean and neat. I quick drive to the beach and to the city! The James Island area was amazing! We will definitely stay again if we are in the area!
Top guest favorite
A charming gazebo is framed by lush greenery, surrounded by manicured shrubs and colorful seasonal plants. The gazebo features decorative lattice walls, allowing natural light to filter through. A winding pathway leads to this serene outdoor space, inviting relaxation amidst the tranquil setting.
Guesthouse in Summerville
4.97 out of 5 average rating, 262 reviews

Summerville’s Tiny Oak Hideaway

JoanneRating, 5 stars1 month ago
our stay at the Tiny Oak was fabulous. We had everything we needed and more. we love being able to walk to everything.
Guest favorite
An open living space showcases a fully-equipped kitchen with stainless steel appliances and a dining area. The lounge features stylish blue and white striped chairs, a cream-colored couch, and wall art above a wooden coffee table, surrounded by natural light from large windows.
Guesthouse in Hampton Park Terrace
4.86 out of 5 average rating, 192 reviews

Serene Location - Next to Hampton Park: Haven Hom

CynthiaRating, 5 stars1 week ago
We totally enjoyed our stay at this cute "bungalow" in Charleston. The communication and check-in process were great, the house had everything we needed and was very clean and tidy. We loved that we had a driveway space to park our car, which is important in any big city. The location is a little off the beaten path, but still walkable to many good spots for food & bev. Would recommend and stay again for sure!
Top guest favorite
A cozy fire pit area features a circular arrangement of dark wooden chairs surrounding a glowing fire. The path is outlined with stone, and lush greenery surrounds the space, creating a welcoming outdoor setting for relaxation and gatherings.
Guesthouse in Charleston
5 out of 5 average rating, 176 reviews

The Guesthouse at Old Orchard

MichaelineRating, 5 starstoday
Spent four nights with a friend in Brandy and Bill’s wonderful guest getaway and wish we could have stayed many more nights. Very clean and well appointed space — the kitchen had everything you need (and then some). Bathrooms were spacious and provided towels and washcloths. Beds were comfortable and there is so much space in this guesthouse. It’s in a quiet neighborhood and the property is very relaxing too. Brandy has created a cozy home away from home and we hope to return again. So many nice well appreciated touches. It’s perfectly located in the area too — so close to many of the attractions and also very close to grocery stores and restaurants. Highly recommend with no reservations!
Guest favorite
A fully equipped kitchen area displays a coffee maker and a single-serve brewing machine on a black countertop. Various storage containers and kitchen utensils are neatly arranged, with decorative items and plants positioned on open shelves above.
Guesthouse in Mount Pleasant
4.96 out of 5 average rating, 309 reviews

Shem Creek Bungalow: Coastal Comfort Redefined

NathanRating, 5 stars1 week ago
Stayed here on a recommendation and the place was perfect. Would recommend it to anyone interested in private little getaway.

Quick stats about guesthouse rentals in Charleston

  • Total rentals

    220 properties

  • Total number of reviews

    25K reviews

  • Family-friendly rentals

    40 properties are a good fit for families

  • Pet-friendly rentals

    60 properties allow pets

  • Rentals with a pool

    10 properties have a pool

  • Rentals with dedicated workspaces

    100 properties have a dedicated workspace

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