
Pet-friendly vacation rentals in Santee
Find and book unique pet-friendly homes on Airbnb
Quick stats about vacation rentals that are pet-friendly in Santee

Nightly prices starting at
Santee vacation rentals start at ﺩ.ﺇ 1,102 per night before taxes and fees

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santee rentals

5 Average rating
Santee stays are highly rated by guests—averaging 5 out of 5!
Top-rated pet-friendly home rentals in Santee
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Tie One On! at 4 Bdr Waterfront Lake Marion
Relax, Recharge and "Tie One On" waterfront on Lake Marion! Welcome to your perfect lake escape! This cozy, pet-friendly retreat offers lovely wrap-around peninsular views, waterfront with a small dock, sunrooms, a spacious yard, and all the comforts of home. Enjoy mornings overlooking the water, afternoons kayaking or fishing, and evenings grilling & gazing at tranquil waters. Modern lake living! (Not on "big water" of Lake Marion but on amply sized arm of Lake Marion separated by causeway)
Outdoor spacesWalkabilityKitchen

Cozy, comfy, convenient, cottage!
We think you'll love this peaceful, family friendly cottage. For a price similar to a local hotel, you'll get a newly remodeled 2-bedroom house complete with kitchen and formal dining room located on fenced in lot 🐶 in quiet neighborhood. The master has a king bed with 400 count Egyptian cotton sheets and a bamboo mattress topper. The guest has a queen bed with a sensafoam mattress. There is a new 50” tv and high speed fiber WI-FI. There is also a breakfast bar with your favorite coffee.
WalkabilityOutdoor spacesHospitality

Mulberry Cabin, a rustic tiny house cabin
Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.
Outdoor spacesWalkabilityAmenities

Congaree Vines - Barn Bungalow by a Vineyard!
-Enjoy a quiet country stay, complimentary port wine from our vineyard, and a fire-pit under the stars! This charming Barn Bungalow is next to our hobby vineyard and meadow walk! -Congaree Vines also offers the Log Cabin Library for guest use & Woodland Cottage to rent. Pets welcome with fee; service dog, provide paperwork. -We are near Congaree National Park (33 min), Columbia, USC, Ft. Jackson, Airport, I-26 & Hwy77. -15% off guided kayaking w/Carolina Outdoor Adventures.
WalkabilityPetsCleanliness

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Recently Remodeled! Private corner unit with panoramic lake views! - Amenities: pool, fishing pier, boat ramp, grill area, boardwalk, walking/biking bridge, parking, wifi - Santee Ntnl Golf Club 6min - Santee Cooper Cntry Club 12min - Lake Marion Golf Club 7min - Santee State Park 9min - Santee Ntnl Wildlife Refuge 24min Smart TVs in bedrooms and living area 2 Dogs allowed - must be included in reservation Only registered guests and pets on site Absolutely no smoking/vaping of any kind
Outdoor spacesIndoor spacesDecor

A relaxing cabin on private pond. Old Bells Secret
Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!
Outdoor spacesPetsHospitality

Log home on Lake Marion inlet w/private dock.
Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.
WalkabilityPetsFamily

Lake Life Living-W/Boat waterfront condo
Nestled in a cozy cove along the shores of Lake Marion, this pet friendly retreat offers an escape for anglers, boaters, and golfers seeking both tranquility and convenience. This 2-bed, 2-bath condo is conveniently located off I95, making it an excellent base for exploring nearby areas. Lake Marion ranks among the largest lakes in the US offering world-class fishing. Santee also provides an exceptional golfing challenge making this a premier vacation destination for the golf enthusiasts.
Outdoor spacesPetsCondition

Lakefront Retreat | Dock, Firepit & Pet Friendly
Wake up to panoramic Lake Marion views, fish from your private dock, relax around the waterfront firepit, and enjoy a peaceful lakefront getaway just steps from the water. Enjoy peaceful mornings, sunset evenings, and easy access to fishing, boating, swimming, and lake life. Pet Friendly: Well-behaved pets are welcome! Please keep pets off furniture and clean up after them inside and outside the property. Multiple pets may be considered case-by-case—please message us before booking.
PetsOutdoor spacesAccuracy

Relaxing Comfortable Waterfront Family Dock Suite
Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.
Outdoor spacesPetsBackyard

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.
Outdoor spacesPetsView

Pet-Friendly Lake Marion Getaway - Just off I-95!
In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.
WalkabilityPetsAmenities
Popular amenities for Santee pet-friendly home rentals
Pet-friendly house rentals

Quaint little getaway!
PetsOutdoor spacesLocation

Lowcountry Retreat
LaundryBathroomLong stay

Lakefront w/ dock at Mill Creek
WalkabilityOutdoor spacesGetting around

Almost Heaven on Lake Marion, SC
Outdoor spacesPetsAccuracy

The Cypress House
PetsOutdoor spacesAmenities

Lakefront home with boat ramp and game room
WalkabilityPetsAmenities

Fish Haven I
Outdoor spacesWalkabilityAccuracy

Large Lakefront Home w/360 view, beaches & dock
PetsOutdoor spacesComfort
Pet-friendly home rentals with a pool

Lakefront Lookout
WalkabilityPetsSleep quality

Wyboo Retreat at Lake Marion W/Pool
Outdoor spacesComfortAccuracy

The Pointe at Eagle Point Pool/Dock Sleeps 23
Outdoor spacesPetsCondition

Lakefront Farmhouse Retreat+Pool at Lake Marion
PetsOutdoor spacesNearby

Spacious Retreat Near Charleston, Pet Friendly
NearbyPoolHospitality

Cheerful 4 bedroom ranch w/ screen porch & fence.
PetsWalkabilityPool

Pool & Fire Pit! 'Outlaw Gameroom' in St Matthews
PetsOutdoor spacesSleep quality

The Azalea Lakehouse
Private, pet-friendly home rentals

Charming Octagon Cabin for a Peaceful Escape
PetsViewIndoor spaces

Big Mama's Lakeside Cottage Lake Marion
Outdoor spacesPetsView

"The Nest" At Maple Hollow
ValueHospitalityComfort

Cutest Cottage on the Lake
Outdoor spacesPetsFamily

Furnished 3BR Near MUSC, SC State & Claflin
Check-inAccuracyLocation

Dockside Villa Lake Marion
WalkabilityOutdoor spacesFamily

Santee/Lizzie's Creek Lakefront
PetsOutdoor spacesParking

Fishing, boating, sunrises, peace & quiet, firepit
Outdoor spacesPetsAccess
Destinations to explore
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- Congaree National Park
- University of South Carolina
- Riverbanks Zoo and Garden
- North Charleston Coliseum & Performing Arts Center
- Magnolia Plantation & Gardens
- Williams Brice Stadium
- South Carolina State House
- South Carolina State Museum
- Cypress Gardens
- Columbia Museum of Art
- Colonial Life Arena
- West Columbia Riverwalk Park and Amphitheater
- Sesquicentennial State Park
- Columbia Metropolitan Convention Center
- Wannamaker County Park
- Edventure
- Riverfront Park
- Soda City Market
- Whirlin' Waters Adventure Waterpark
- Koger Center for the Arts
- Charleston Southern University
- Azalea Park
- Bee City Zoo & Honey Bee Farm
- Frankie's Fun Park





