Lake house vacation rentals in Santee

The image showcases a private dock extending into the lake, with a small platform at the end. Behind the dock, a spacious home is visible, surrounded by trees and an expansive yard, creating a tranquil lakeside setting.

4.89 out of 5 average rating, 83 reviews

Lakefront home with boat ramp and game room

This beautiful home is perfect for your Marion Lake family vacation! With four bedrooms and two living rooms, there is plenty of space! Our home is kid friendly, and includes toys, books, board games, arcade games, foosball, and puzzles. Outside you will find plenty of seating and dining areas, a large yard, a fire pit, a grill, beach along the waterfront, a private dock and a private boat ramp. Perfect for swimming, fishing, and boating! Kayaks are available.

4.95 out of 5 average rating, 43 reviews

A serene lakeside view captures a wooden dock extending into calm waters, surrounded by trees. Buildings are visible in the background, subtly illuminated by dusk light. The sky displays gentle hues of blue and pink, reflecting the tranquil atmosphere of the location.

Home in Vance

Lakefront w/ dock at Mill Creek

Nestled between Santee & Eutawville, Vance is less than an hour from Downtown Charleston. Experience lake life w/ a front row seat to live music, dancing & karaoke at the Mill Creek Marina! Float over to grab a bite or drink at the Barefoot Lakeside Bar & Mill Creek Food & Spirits! Community hosts golf cart parades, Halloween bash, & a spectacular 4th of July fireworks show. Launch your pontoon a few doors down, tie up at your dock & conveniently fuel up at the marina. Campground store on site!

A scenic view of Lake Marion is presented, featuring a wooden dock extending into the water. A picnic table is situated on the grassy shore, beneath a large tree. A flag waves gently in the breeze, adding a touch of patriotism to the serene landscape.

4.97 out of 5 average rating, 35 reviews

Lake House at Lake Marion

Beautiful lakefront 3 Bedrooms/2 full baths with million dollar view of Lake Marion. -2 Queen beds/2 twins/1 futon -Washer/Dryer -Screened porch -Private Dock - fish in “big water” -Canoe & Kayak -Fire pit -Includes linens & beach towels & more! -Fully Furnished + grill & carport -One level open concept -75” Roku TV & Roku in Master and WiFi -great safe neighborhood for walking & bike riding -NO HOUSE PARTIES or events. -public boat landing &county park with playground within 2 blocks.

A charming house is featured, with a well-maintained front yard and stone walkway leading to a welcoming porch. Lush greenery surrounds the entrance, and the architectural details include gabled roofs and decorative elements on the facade. Sunlight casts a warm glow over the exterior.

4.93 out of 5 average rating, 42 reviews

Lakeview Leisure-Face to the Sun

At this unique and tranquil getaway, your day can be whiled away on the porch, poolside or in the hot tub. Or pack a cooler and spend the day on Lake Marion. Tie your boat off on the dock and head just down the road to Santee for a round or two at Santee National Golf Club. Located conveniently between Columbia and Historic Charleston you are never out of options to stay as busy as you like. End the day with a cocktail on the back porch, steaks on the grill and a game of pool. Enjoy life!

4.97 out of 5 average rating, 32 reviews

Home in Manning

Lakefront Retreat | Dock, Firepit & Dog Friendly

Wake up to panoramic Lake Marion views, fish from your private dock, relax around the waterfront firepit, and enjoy a peaceful lakefront getaway just steps from the water. Enjoy peaceful mornings, sunset evenings, and easy access to fishing, boating, swimming, and lake life. Dog Friendly: Well-behaved pets are welcome! Please keep pets off furniture and clean up after them inside and outside the property. Multiple dogs may be considered case-by-case—please message us before booking.

4.94 out of 5 average rating, 189 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

A spacious lakefront home is visible from the water, surrounded by lush green trees. The two-story structure features porches on each level. A sandy beach area and grassy yard lead up to the house, with white lounge chairs placed nearby, inviting relaxation by the water.

4.93 out of 5 average rating, 57 reviews

Large Lakefront Home w/360 view, beaches & dock

This family-friendly spacious lakefront home with dock is located on a peninsula and boasts water access on three sides of the property. Park your boat at your own personal dock using the boat ramp located directly across from the property. This property has room for 13 people, but there is also access to an air mattress. Enjoy the 3 huge porches, fire pit, hammocks and swings, fishing, drop in one of the kayaks or paddle boards straight off the property and head out to Lake Marion.

4.97 out of 5 average rating, 39 reviews

Almost Heaven on Lake Marion, SC

Enjoy a serene getaway at our lake front spacious 3-bedroom, 2-bathroom lake house. Features include a king-size master bedroom with en-suite bathroom, queen and two full-size beds in other rooms, fully equipped kitchen, winter-only fireplace, screened porch with ample seating, smart TVs in all rooms, high-speed Wi-Fi, gas BBQ, private sandy beach, covered dock with power and seating, boat ramp, and ample parking. Dog-friendly (no cats). location provided after booking.

A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.

4.99 out of 5 average rating, 134 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

4.81 out of 5 average rating, 31 reviews

Lake Marion | Chill, Cruise, or Cast a Line for 8!

Wake up to quiet mornings, sip coffee by the water, cast a line, and let the day slow down. This Lake Marion home is all about relaxing, fishing, and unplugging with your favorite people. This is the perfect place to reset, recharge, and enjoy the simple things. No rush. No noise. Just lake life, done right. PS: this IS a fresh water lake in SC with a lot of wildlife, including alligators...swim, fish, and play at your own risk.

A serene lake view appears at dusk, with gentle water reflecting the sky. A wooden dock extends into the lake, accompanied by scattered benches on the shoreline. Spanish moss drapes from nearby trees, adding to the tranquil ambiance.

4.73 out of 5 average rating, 45 reviews

Lake House for Perfect Getaway

Forget your worries in this spacious and serene space. This 3 story home offers 6 bedrooms and 4 bathrooms and large enough to house your entire family. Make it a day on the lake and catch some sun on the extended dock. Bring your boats or jet skis to enjoy the beautiful Lake Marion. When hunger hits, grill up your favorites before shooting some hoops or shooting a game of pool.