Vacation rentals in Orangeburg County

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Top-rated vacation rentals in Orangeburg County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

The bedroom features a spacious bed dressed in white linens with red accents. A desk with dual monitors is positioned next to the bed. A dresser and a soft area rug add warmth, while natural light filters in through a window with light drapes.

Home in Orangeburg

4.95 out of 5 average rating, 37 reviews

Theo's Place

Kick back and relax in this calm, stylish space. I'm happy to offer my 1st home as a host, providing all the amenities I've wanted as a guest in my years of successful stays on the AirBnB platform as a guest (laptop not included). My guest will find various comforts and additions to make their stay as comfortable as can be. I welcome your feedback. My home is available as a 1 Bedroom with a large Den, Living & Dining rooms, 2 Bathrooms, full Kitchen and Laundry room. All new appliances as well.

Top guest favorite

The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.

Cabin in Rowesville

4.95 out of 5 average rating, 172 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Guest favorite

A single-story brick ranch home is set in a green, well-maintained yard. A large palm tree is situated near the entry, with a few steps leading up to the front door. The front porch features two rocking chairs, enhancing the welcoming appearance of the home.

Home in Orangeburg

5 out of 5 average rating, 62 reviews

Trendy, cozy and casual

Total Renovation of 1235 square feet brick ranch with 1 car garage, screened in back porch and large fenced back yard. 2 baths, updated fully equipped kitchen, dishwasher, new floors, curtains & linens. Roku TV, wireless internet. Washer and Dryer Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged per pet. Pets are welcome but there is a pet fee based on number of dogs and breed. Some breed are restricted by insurance company. Contact me before booking please.

Top guest favorite

A spacious living area features a large blue sectional sofa adorned with patterned cushions. A light wooden coffee table sits on a soft area rug, complemented by a small potted plant. Natural light filters through the windows, creating a bright and welcoming environment.

Home in Orangeburg

5 out of 5 average rating, 128 reviews

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Guest favorite

An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.

Home in Santee

4.97 out of 5 average rating, 141 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Superhost

An outdoor seating area features two high chairs and a small table, positioned on a concrete patio. The serene pond is visible beyond a wooden railing, surrounded by lush greenery, inviting a tranquil atmosphere for relaxation.

Tiny home in Orangeburg

4.76 out of 5 average rating, 17 reviews

Tiny Pond House

Reconnect with nature at this unforgettable escape. The best part of our pond cabin is the view! The outdoor space can be utilized to take in fresh air and escape the busyness of life and far outweighs the tiny square footage. Escape, relax and enjoy your home away from home. Our home is meant for one to two people to have a cozy, minimalistic experience but comes with all the amenities. All are welcome to use of the pond , so feel free to bring your fishing rods & tackle.

Top guest favorite

A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.

Home in Summerton

4.99 out of 5 average rating, 117 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Top guest favorite

An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.

Apartment in Orangeburg

4.99 out of 5 average rating, 124 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Top guest favorite

A renovated camper is set amidst towering trees, adorned with string lights that create a warm glow at dusk. A wooden deck with steps leads to the entry, while a fire pit sits nearby on the lush green lawn.

Camper/RV in Santee

5 out of 5 average rating, 29 reviews

Renovated Camper Farm Stay

Escape to rural tranquility just an hour from Charleston, SC. Our unique renovated camper offers 2 bedrooms, 1 bathroom, and a deck overlooking our charming farm. Enjoy WiFi, farm-fresh eggs, and a personal fire pit amidst 54 acres of nature trails. Immerse yourself in modern farmhouse style while interacting with our friendly farm animals. Perfect for a peaceful retreat to relax and recharge.

Top guest favorite

A spacious bed is dressed with a light patterned duvet and decorative pillows. A black nightstand is positioned beside the bed, topped with a textured lamp and a small potted plant. The backdrop features green wainscoting, adding a calming touch to the room.

Apartment in Barnwell

4.99 out of 5 average rating, 112 reviews

Ellzey Place

Ellzey Place is a peaceful spot where you can relax and unwind. Enjoy having a cup of coffee on the deck facing a spacious private back yard. There are lots of azaleas that bloom in season and pines swaying in the breeze. It is a charming apartment attached to the owner's house but has a private deck and entrance. It has been newly remodeled and delightfully decorated.

Superhost

A quaint cottage is nestled among trees, showcasing a wooden façade and a sloped roof. A hammock rests on the side, inviting relaxation. Rocking chairs are placed on the porch, while a white door leads into the interior. Natural light filters through the greenery.

Tiny home in Blackville

4.89 out of 5 average rating, 149 reviews

Spanish Moss (Carolina Cottage)

Enjoy the sounds of nature when you stay in this unique place. Wildlife, Magnolia’s, trees, Spanish Moss draped 200 year old Oak trees, Pecan Orchard Views. Private gated drive to cottage. The Bungalow at Magnolia is located on the same property which does not allow pets 120 feet distance wooded unable to see cottages from each other. 420 friendly property.

Guest favorite

A covered entryway leads to a private entrance of the residence, featuring a white door with a welcome sign. Outdoor seating with a table and chairs is visible, along with a small garden area. The American flag is displayed nearby, set against a backdrop of greenery.

Guesthouse in Bowman

4.97 out of 5 average rating, 65 reviews

Adorable 2 bedroom guesthouse in Bowman, SC.

Relax with the whole family at this peaceful place to stay. Private, rural area. Ease of access to I-26, I-95, and Hwy 301. Santee, SC is 15 minutes away with golfing, Lake Marion, and a small water park. Central to Columbia, Charleston, Florence, and Savannah, GA.