House vacation rentals in Orangeburg County

Find and book unique houses on Airbnb

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Popular amenities for Orangeburg County house rentals

House rentals with a pool

Guest favorite
Home in Orangeburg
4.96 out of 5 average rating, 79 reviews

Colonial Farmhouse - 6 bedroom with a pool

Dorothy AnnRating, 5 stars3 days ago
I wanted my parents to experience the convenience of an Airbnb, where we all were under one roof. They were excited, we were able prepare our dishes for family gathering and the kids
Guest favorite
Home in Williston
4.91 out of 5 average rating, 23 reviews

Out Aways House with a POOL on a POND

CoryRating, 5 stars6 months ago
Such a beautiful home in a great location. The crew really enjoyed their stay. Thanks for the hospitality!! Would recommend to anyone.
Guest favorite
Home in Eutawville
4.95 out of 5 average rating, 63 reviews

Heated Indoor Pool on Lake Marion with Dock

HollyRating, 5 stars3 weeks ago
It was a great place for our whole family. It checked all the boxes for everyone. Fishing was our #1 box, having the boat dock was wonderful. They didn't have to take the boat in and out of the water everytime they fished. The indoor swimming pool was great for the kids and adults because you didn't have to wait for warm weather. The pool table was fun for all and we could all hang together in the spacious area. The kitchen was large and clean with everything you would need. We all had a great relaxing vacation. Would highly recommend this place! Working with Ingrid was wonderful! She was extremely helpful and was available when we needed her. Would love to check out her other properties. Thank you for everything Ingrid!
Guest favorite
Home in Santee
4.94 out of 5 average rating, 49 reviews

Lakefront Lookout

DeborahRating, 5 stars3 days ago
We loved this place. The lake view was great to see. The host answered the few questions we had very promptly. The house was clean and had everything. We loved walking around down by the pier and also enjoyed hanging out by the pool, which also overlooks the lake. The book with instructions and notes was also super helpful. We had a very good stay and our family of 3 enjoyed this spot.
Superhost
Home in Summerton
4.86 out of 5 average rating, 14 reviews

Lake Marion Oasis with Pool

DonnaRating, 5 stars3 days ago
We had a fantastic stay - the home is very clean and provided us with everything we needed to have a very comfortable stay. The yard, pool, decking and dock are beautiful and the setting itself is quiet and relaxing. We would definitely recommend this rental and will be booking it again.
Home in Summerton
New place to stay

Lakeside Dreams W/Pool & Spa

AngelaRating, 5 stars1 week ago
We absolutely loved this place. My husband active duty Navy and I a veteran. We were in South Carolina from California for his father’s funeral. I booked this property for my family to have a place to gather and to give them a bit of relaxation despite the circumstances. Everyone adored the place and enjoyed themselves. Stuart was an amazing host, very kind, accommodating and responsive. When we visit the area again we hope to book this property again or one of his others. Definitely worth it.

Weekly house rentals

Guest favorite
Home in Summerton
4.88 out of 5 average rating, 41 reviews

The Fishnet

ShaneRating, 5 stars1 month ago
Perfect place to stay for quick access to the lake and very clean. Great neighborhood.
Home in Summerton
4.83 out of 5 average rating, 18 reviews

Idyllic Waterfront Escape w/ Private Boat Dock!

RosaRating, 5 stars8 months ago
The host was super responsive. The house was clean, beautifully decorated, included all the necessities. The location was great, enjoyed the proximity to restaurants, shopping, and golf. Lake was spectacular!
Guest favorite
Home in Summerton
4.95 out of 5 average rating, 20 reviews

House of the Rising Sun

RayRating, 5 stars3 weeks ago
Great view of lake! Location was perfect for our group since we were there to fish. We were able to park our 3 trucks & boats with no problems as well as 2 other vehicles.
Top guest favorite
Home in Salley
4.96 out of 5 average rating, 23 reviews

Copper Penny

BrentleyRating, 5 stars5 days ago
The place is exactly as advertised. House was clean and we'll kept. Bed was comfortable and we slept great. Shower had plenty of towels and toiletries. Enjoyed our stay.
Top guest favorite
Home in Orangeburg
5 out of 5 average rating, 20 reviews

Home away from home

JamieRating, 5 stars6 days ago
It's a beautiful place to stay in Orangeburg. Last time we was there we stayed in a Hotel by the freeway and this was so much better.
Guest favorite
Home in Santee
4.97 out of 5 average rating, 154 reviews

Santee lakefront home, big water right off I-95

EmilyRating, 5 stars4 months ago
Amazing place to spend a few days!! Loved the lake views! :) Wonderful and spacious rooms! Located in a quiet and peaceful area. Minutes to drive into town and grab groceries or necessities for the trip! Fantastic dock for walking out on to the lake! Would definitely stay again!
Top guest favorite
Home in Orangeburg
4.97 out of 5 average rating, 30 reviews

Theo's Place

ChelseaRating, 5 stars1 month ago
Neighborhood was noisy and busy, but location was very close to hospital where I was working for the week. Had all the amenities I needed.
Guest favorite
Home in Denmark
4.92 out of 5 average rating, 108 reviews

Lowcountry river life

DorusRating, 5 stars1 week ago
During our second stay on the river, we found the house to be even cozier than before, thanks to recent improvements. The highlight of our evenings was undoubtedly the dock, where we spent hours relaxing by water, soaking in the beautiful river/swamp setting. This spot not only served as a perfect place to unwind but also functioned as our ideal put-in and pull-out point for floating down the river, making our outdoor adventures even more enjoyable and accessible.

Private house rentals

Home in Bowman
4.83 out of 5 average rating, 6 reviews

Victorian Farmhouse in South Carolina

BillRating, 5 stars5 months ago
we were very satisfied with the home. it was beautiful, quaint, full of love and care. Will definitely go back next time I'm in the area.
Home in Summerton
4.84 out of 5 average rating, 51 reviews

Family friendly lakefront home with boat ramp

KalieRating, 5 stars1 month ago
We loved it here. I felt safe in the neighborhood… neighbors were friendly! This is a very rural location, not much to do in town but we came to enjoy peace and quiet and some hiking at the national forest. It’s exactly what we needed.
Guest favorite
Home in Eutawville
5 out of 5 average rating, 9 reviews

Fisherman’s stay! Lake Getaway!

CurtisRating, 5 stars4 days ago
Very nice house. Safe neighborhood that my boys could take a short walk to the water and bank fish between our main fishing trips out on my boat. Enough parking for a 20 ft lund and 24ft pontoon with 3 trucks in driveway. Shaded lot with nice covered area to hang outdoors. Boat landing less than .5 mile away.
Home in Summerton
4.78 out of 5 average rating, 63 reviews

Flip Flop Inn - Short Walk to Boat Ramp!

KerriRating, 5 stars6 days ago
Good place to stay.Would stay again. Very quite 15-20 min drive to store or restaurant. We stayed in April some of the lake restaurants were still closed for the winter
Home in Orangeburg
4.68 out of 5 average rating, 28 reviews

RayneBow Royalty

AdriannaRating, 5 stars2 months ago
Needed a few days to relax with family. Had a nice time at Sunny’s house. Had enough space for my family of six. Very comfortable. Really enjoyed the recliners in the living room.
Home in Santee
4.63 out of 5 average rating, 78 reviews

Cozy 3 Bedroom Farmhouse

CatrinnaRating, 5 stars1 month ago
The house is very neat and clear. The neighborhood was very peaceful and quiet. We didn’t have any problems with getting into the home. The instructions were posted on what to do. I would rent it again if I’m in the area.
Guest favorite
Home in Summerton
4.87 out of 5 average rating, 39 reviews

Lake life paradise!! Lake Marion waterfront.

JamesRating, 5 stars1 month ago
Place was nice and as described Had a great time the dock was a great place to sit and enjoy the great outdoors House was very roomie and clean A little bit away from restaurant and the golf courses we played But over all great place and private
Home in Summerton
4.83 out of 5 average rating, 29 reviews

Dukes Street Retreat 5min from I-95

AnthonyRating, 5 stars4 months ago
What a wonderful stay! Returning customer, and was even more enjoyable than the first time around! Can’t wait to come back and visit again!

Destinations to explore