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Pet-friendly vacation rentals in Orangeburg County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Orangeburg County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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A cozy bedroom is featured with a spacious bed adorned in a patterned quilt and colorful pillows. Two windows are dressed with light green curtains, allowing natural light to enter. A lamp and a decorative vase enhance the calming ambiance, while a wooden dresser adds functionality.
Home in Orangeburg
4.86 out of 5 average rating, 36 reviews

Nene's Cozy Corner

Time to get Cozy. Relax here with your family and friends at this peaceful place to stay. Or stay if in the area for work. Close to Edisto Memorial Gardens, 8 miles to South Carolina State University, 9 miles to Claflin University, a couple of minutes away from the drag strip, 11.5 miles from The Hillcrest Golf Club and close to many restaurants, stores and shopping centers. Come kickback and relax at “Nene’s Cozy Corner”. Extra parking in front and back yard for motorbikes, boats, cars and more

Top guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 204 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Guest favorite
A serene lakeside view captures a wooden dock extending into calm waters, surrounded by trees. Buildings are visible in the background, subtly illuminated by dusk light. The sky displays gentle hues of blue and pink, reflecting the tranquil atmosphere of the location.
Home in Vance
4.94 out of 5 average rating, 17 reviews

Lakefront w/ dock at Mill Creek

Nestled between Santee & Eutawville, Vance is less than an hour from Downtown Charleston. Experience lake life w/ a front row seat to live music, dancing & karaoke at the Mill Creek Marina! Float over to grab a bite or drink at the Barefoot Lakeside Bar & Mill Creek Food & Spirits! Community hosts golf cart parades, Halloween bash, & a spectacular 4th of July fireworks show. Launch your pontoon a few doors down, tie up at your dock & conveniently fuel up at the marina. Campground store on site!

Guest favorite
A single-story brick ranch home is set in a green, well-maintained yard. A large palm tree is situated near the entry, with a few steps leading up to the front door. The front porch features two rocking chairs, enhancing the welcoming appearance of the home.
Home in Orangeburg
5 out of 5 average rating, 67 reviews

Trendy, cozy and casual

Total Renovation of 1235 square feet brick ranch with 1 car garage, screened in back porch and large fenced back yard. 2 baths, updated fully equipped kitchen, dishwasher, new floors, curtains & linens. Roku TV, wireless internet. Washer and Dryer Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged per pet. Pets are welcome but there is a pet fee based on number of dogs and breed. Some breed are restricted by insurance company. Contact me before booking please.

Top guest favorite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 234 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Top guest favorite
A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.
Guest suite in Eutawville
4.8 out of 5 average rating, 102 reviews

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Guest favorite
A welcoming sign for Elloree displays the phrase "The Home I Love" along with the year established, 1886. The sign is surrounded by greenery, enhancing the invitation to explore the charming community. The road is visible in the background.
Home in Elloree
4.79 out of 5 average rating, 53 reviews

Country Resting Spot

This cozy 2-bedroom, 2-bathroom single-wide manufactured home offers a peaceful retreat in a serene rural setting. Situated on a spacious lot with a large yard, this property provides ample outdoor space for relaxation and play. Conveniently located near Lake Marion. Lcoated off I95 - west about 12 mins (striaght shot). Just west of Elloree SC about 2-3 miles. Perfect layover for that long drive. no smoking inside or vaping inside We love your pets! $12 per pet per night.

Guest favorite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 175 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top guest favorite
Home in Summerton
4.95 out of 5 average rating, 20 reviews

Nanny’s Lake Retreat

3 BR, 2 BA. Located in a quiet, dead end community. Enjoy the lake sounds from the spacious screened in porch. The porch has a swing, rocking chairs, and table with chairs. The den boasts a beautiful gas log fireplace and has two futons and a loveseat. The house is located in a golf cart community on a cove. Sandy beaches are just minutes away depending on the lake levels. Whether you’re looking for a vacation destination or fishing/hunting trip you will love this home.

Guest favorite
Cottage in Blackville
5 out of 5 average rating, 18 reviews

House on Healing Springs Rd

Welcome to your cozy retreat in the heart of Amish country, surrounded by lush greenery and a private backyard! Inside, you’ll find a spacious living room, a fully equipped kitchen, and a comfortable sitting area. The cottage is just a two-minute walk from the famous Healing Springs, where you can relax and restore in nature’s beauty. Right next door, you’ll discover a small Amish store offering their best local sandwiches, baked goods, and other delights.

Guest favorite
A charming one-story house features a welcoming front porch with two black doors framed by flower pots. An American flag hangs above, and steps lead to the entrance. Greenery surrounds the porch, complemented by a stone pathway and a well-maintained yard.
Bungalow in Blackville
4.92 out of 5 average rating, 53 reviews

Clover Cottage

Clover Cottage is a cozy place to stay if you need a quiet place to unwind. Located on Main Street, Clover Cottage is walking distance to restaurants and grocery store. The cottage is a completely renovated property which started life as the summer kitchen for the main house. The cottage is 150 years old and has maintained the charm of a historic home. To retain the history of the property and town, NO SMOKING or VAPING is allowed on the property.

Guest favorite
A spacious outdoor area is featured, showcasing a heated saltwater pool surrounded by lounge chairs. An umbrella provides shade, and lush greenery and trees line the background, which overlooks a serene lake. The open sky is bright with fluffy clouds.
Vacation home in Summerton
4.95 out of 5 average rating, 122 reviews

Lakefront Paradise W/Pool/hot tub/outdoor kitchen

Brand new heated saltwater pool, hot tub and outdoor kitchen area. This upgraded home is ready to host your family or large group! Enjoy breathtaking sunsets year round from your private beach directly on the big waters of Lake Marion. Spends evenings out on the dock fishing or pull your boat right up to the beach. Ping pong and bumper pool tables, fast wifi and big screen tv's make for the perfect entertaining space for large groups.

Popular amenities for Orangeburg County pet-friendly home rentals