Vacation rentals with lake access in Santee

Find and book unique lake access rentals on Airbnb

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Popular amenities for Santee lake access rentals

Lake access house rentals

Top guest favorite
A serene view of a private dock extending into a calm lake, leading to a gazebo surrounded by lush green trees. Reflections of the trees are visible on the water's surface, enhancing the tranquil atmosphere of the lakefront setting.
Home in Irmo
4.98 out of 5 average rating, 60 reviews

Livin' the Lake Life! Home w/dock/gazebo-Sleeps 8

MaryRating, 5 stars5 days ago
The lake house was great. Everything was very clearly labeled, organized, and well thought out. Sara thought of everything. It was very comfortable, and check out was especially easy. It was so nice to not have to strip the beds, wash the towels, take the trash to the curb, etc that so many other airbnbs make you do.
Top guest favorite
Home in Summerton
5 out of 5 average rating, 22 reviews

The Heron Lake House

SamanthaRating, 5 stars1 week ago
The perfect stay! Beautiful lake, clean and gorgeous house, quiet neighborhood and amazing bang for your buck. We've stayed at a dozen Air B&B's and this was top 3! Plenty of space for our family of 5 (though could have EASILY fit another 3-5 guests). Never felt like we were falling over one another. Great fishing location (though we only caught one fish, haha), calm waters and breathtaking sunrise/sets. About an hour drive from the beach at Charleston (highly suggest Folly Beach). Morgan was responsive when we had questions and was always super kind.
Guest favorite
An aerial view captures the property layout along Lake Moultrie. A dock extends into the water, surrounded by lush greenery and trees. The home and additional buildings are visible, highlighting the spacious lawn and natural surroundings.
Home in Bonneau
4.91 out of 5 average rating, 32 reviews

Hideaway on Lake front for 7 guests

MasaRating, 5 stars3 weeks ago
Very clean and spacious house with more than reasonable stocked items made us feel at home the minute we stepped in. Inside, tasteful furnitures and decoration gave us a cozy feel as if we are staying at my grandmother’s house. Outside, you can spend all day relaxed with the sounds of nature - water, wind, and birds. I tried kayaking for the first time. Water is calm, nothing else is around me except water. What a soothing experience! And the sunset is breathtaking.
Superhost
A wooden dock extends into the calm water, leading to a viewing platform at the end. Green grass borders the shore, and the sky is filled with fluffy white clouds, creating a serene backdrop for the tranquil lake scene.
Home in Manning
4.86 out of 5 average rating, 7 reviews

Cozy 3 bed 2 bath waterfront lake house

KissahRating, 5 stars3 weeks ago
The host was great and the place was as described. We had enough space for everyone to sleep. I wish we had more time to enjoy the water but our schedule did not allow.
Guest favorite
Home in Chapin
4.91 out of 5 average rating, 81 reviews

Casa Azul - Lake Murray - Close in - Spa like bath

ScottRating, 5 stars8 months ago
We enjoyed our week at the lake and found the home well-stocked. We ate most of our meals at home and had everything we needed. The kitchen was nicely appointed, and the appliances were high quality. There is a Publix grocery store 10 minutes away and several local restaurants to enjoy. We used the charcoal grill for several meals and sat outside as much as possible. The whole family enjoyed the kayaks, paddle boards, canoes, and swimming in the lake. A ladder on the dock would make it easier to get out of the lake, but we made due.
Guest favorite
Home in Chapin
4.94 out of 5 average rating, 52 reviews

Relaxing 3-Bed lakefront home w/large screen porch

EmilyRating, 5 stars3 weeks ago
This place was absolutely beautiful. It was spacious enough for our family to enjoy each other and also relax. The house is very spacious and well equipped with everything you need.
Guest favorite
A wooden dock extends over still waters, showcasing a tranquil lakefront scene. An umbrella provides shade, while lush green trees surround the area, reflecting gently on the water's surface. Several boats can be seen nearby, highlighting the access to recreational activities.
Home in Manning
4.88 out of 5 average rating, 48 reviews

Cozy Church Branch Cabin

BarbaraRating, 5 stars6 days ago
The cabin is very cozy. We felt at home the moment we walked in. Morning coffee and evening cocktails on the deck overlooking the water was amazing. Catelyn thought of everything. Fully equipped kitchen and plenty of towels in the bathrooms.
Guest favorite
A scenic view of a lake house property set against a backdrop of dense trees. The main house is visible, featuring a covered deck and large windows. A dock extends into the lake, with a boat house positioned to the left, enhancing the outdoor setting.
Home in Chapin
4.86 out of 5 average rating, 71 reviews

Best View on Lake Murray located in Chapin SC

KimRating, 5 stars3 weeks ago
My husband and his friends have stayed multiple times at Chris's house and love it. Great location and love the house. Perfect location for their annual spring fishing trip. Chris is always quick to respond and help in any way. Thank you for sharing your home! Kim Cash

Lake access apartment rentals

Guest favorite
A serene lakeside view features colorful Adirondack chairs positioned on a grassy area. The sun sets in the background, casting warm hues over the water. Large trees provide shade, enhancing the peaceful atmosphere of the outdoor space.
Apartment in Moncks Corner
4.79 out of 5 average rating, 14 reviews

Ophir Oasis Unit #1

LeeRating, 5 stars3 weeks ago
Not my first time here, great place, frank is a great host. On top of everything, answers whenever you need him. See you next time, Frank.
Top guest favorite
Apartment in Chapin
5 out of 5 average rating, 14 reviews

Luxe Lakefront Apartment w/ Shared Pool & Dock!

AnielaRating, 5 stars5 months ago
Jeff and Elizabeth are great hosts! They made us feel incredibly welcome from the moment we walked through the door. They made fresh bread and had it waiting for us, along with an invite to a community event. Elizabeth and Jeff are lovely people and made us feel right at home. My teenage son told me to definitely book with them again next time I’m in town.
A serene view captures a community pool bordered by lush greenery and palm trees. The lake reflects a pastel sunset, enhancing the tranquil atmosphere. Chairs are arranged around the pool, inviting relaxation. A well-maintained pathway leads through the landscape towards the water's edge.
Apartment in Santee
4.67 out of 5 average rating, 3 reviews

Lake and pool side vacationing

MelissaRating, 5 stars10 months ago
The view was incredible and completely worth the trip. This condo was comfortable and inviting. The pool was great for the kids and having fishing right there was very convenient. There was a light bulb out over the kitchen table but we made due. The kitchen is small but appliances all seemed new. Having a washer and dryer was great for drying all our beach towels. The outside sitting area needs a little extra attention. We were in the area for a high school graduation so can’t speak to things to do in the area. But the view was awesome and we would definitely consider coming back when we visit family.
Guest favorite
An outdoor balcony features a dining table surrounded by four mesh chairs. A ceiling fan is visible above, and the view includes a serene lake framed by trees under a clear blue sky.
Apartment in Santee
5 out of 5 average rating, 5 reviews

Relaxation is the plan

TInaRating, 5 stars3 weeks ago
We stayed for one night on our trip from FL to PA to take a break from traveling. I wish we would have had more days to stay. The location right off of I-95 next to the lake was so refreshing. Everything was just as described , super clean and decorated nicely. I accidently left a necklace there and they communicated with me immediately and had it in the mail with tracking the same day. We would definitely stay here again !!
Guest favorite
A single-story building features a light-colored exterior with a metal roof and an attached carport. The adjacent area includes a small outdoor seating arrangement with four chairs surrounding a table, situated on a well-maintained lawn with tall grass.
Apartment in Pineville
5 out of 5 average rating, 7 reviews

Our Place at the Lake.

SusanRating, 5 stars6 months ago
Perfect place to unplug and relax for the weekend. Fire pit was fantastic and the outside table was a great place to sit enjoy the perfect weather.
The three-story brick property is situated along Lake Murray, featuring a striking blue metal roof. Lush green landscaping surrounds the home, which includes multiple balconies and a spacious front yard. A boat is moored nearby, providing easy access to the water.
Apartment in Irmo
4.91 out of 5 average rating, 22 reviews

Large 1 bedroom apt/boat ramp &dock on Lake Murray

AprilRating, 5 stars8 months ago
It was very comfortable and homey. Quick drive to Columbia, very peaceful to come back to and relax after exploring. Beautiful view of Lake Murray with plenty to do and stores very close by. The hosts were very accommodating. They had refreshments, snacks, and basic necessities needed. Would highly recommend and would stay at again. ….thank you very much!!!!!!!
An aerial view of the property reveals a cluster of buildings bordered by lush greenery and a peaceful lake cove. Cars are parked along a paved area, with pathways leading through landscaped grounds. The calm water reflects the surrounding trees, creating a serene setting.
Apartment in Santee
4.63 out of 5 average rating, 8 reviews

Dockside Villa Lake Marion

AlyssaRating, 5 stars1 month ago
Lovely stay. It was a beautiful area with a view looking over the lake. Will definitely stay again!

Lake access cottage rentals

Guest favorite
A wooden dock extends over calm waters, leading to a spacious green lawn surrounded by trees. A screened-in porch with seating is visible in the background, providing a relaxing space to enjoy the tranquil lakeside atmosphere.
Cottage in Chapin
4.93 out of 5 average rating, 86 reviews

Waterfront Cottage on Lake Murray w/private dock

RogerRating, 5 stars3 months ago
The Sandbar Cottage was everything we wanted it to be. Candy was very responsive before our visit answering any questions that I had about the location and stay. During our visit she was super responsive as well, allowing me to modify and stay a bit lengthier than we had planned. We traveled as a couple, with our two dogs and bass boat. The accommodations for all were great and just has had been explained. The pet area was super convenient and on the property boat ramp worked out great for us. I recommend getting there in daylight the first day just to take a look around as to how you need to pull in for the ramp and such, my outfit is around 50’ total length. We were able to get settled in make great use of all. I can’t say enough how comfortable the cottage was and warming atmosphere. The first two days of our stay the weather didn’t cooperate. But the cottage was set up with a warm Christmas appearance and the open porch leading to a fenced in area was great for our pups.
Top guest favorite
Cottage in Columbia
4.97 out of 5 average rating, 512 reviews

The Historic Selwood Cottage @theselwoodcottage

JenniferRating, 5 stars1 day ago
This is our fourth or fifth time staying at Kristin's ~ which tells you all you need to know. It is our VERY FAVORITE AirBnB! In fact, we've moved vacation dates around just so we could stay here on our way to Florida! Everything about it is amazing! There were even some updates since we last stayed, which took things to a whole new level! It is a great value and the perfect place! Super highly recommend and we can't wait to go back!
Top guest favorite
A cozy living area features large windows providing views of the waterfront. A plush sofa and swivel chair are arranged around a coffee table, with a flat-screen TV visible on a stylish media console. A sleek granite countertop is positioned at the kitchen's edge.
Cottage in Chapin
4.97 out of 5 average rating, 150 reviews

Gamecock Cottage @ Lake Murray-Waterfront w/ Dock

CaitlinRating, 5 stars4 days ago
This is one of our favorite places to spend a weekend on Lake Murray! It’s such a comfortable space with an incredible view and we enjoyed spending the day enjoying the lake and relaxing. The cottage has everything you could possibly need, and the check in was so easy. The hosts were kind and accommodating and we will definitely be back! Grocery store is only 5 minutes away if you need to grab anything on the way in. If you’re looking for the perfect lakefront getaway—This is it!!!
A welcoming cottage is presented with a bright red front door. Surrounded by tall pine trees, the exterior features a white façade and a spacious porch with railings. Two windows on either side of the door allow natural light to enhance the inviting appearance.
Cottage in Dorchester County
4.78 out of 5 average rating, 27 reviews

Relaxing 2-bedroom cottage, Dorchester, S.C.

AudreyRating, 5 stars3 months ago
Beautiful, serene, lovely home. Would highly recommend.
Superhost
A cozy living room is depicted with neutral-toned walls and soft carpeting. A green-patterned sofa is complemented by a textured armchair, while a light-colored coffee table sits at the center. A floor lamp provides warm lighting, and decorative elements include wall art and potted plants.
Cottage in Summerton
4.61 out of 5 average rating, 99 reviews

The Fish House

DawnRating, 5 stars34 months ago
Great place to stay with dock access. We enjoyed ourselves and had a wonderful weekend. Everyone in the neighborhood was very polite and kind. My family would love to spend time here again. Kayaking from the boat ramp was a bonus.
Guest favorite
A screened porch is presented with a small table and two chairs, overlooking a serene lake view. Two cups of coffee are placed on the table. Lush greenery surrounds the area, creating a peaceful atmosphere.
Cottage in Manning
5 out of 5 average rating, 14 reviews

Big Mama's Lakeside Cottage Lake Marion

SharynRating, 5 stars2 weeks ago
We had the time of our lives. The place is great. Great location. Jamie Sue and husband could not be nicer. This place could be the best kept secret in South Carolina. PS some of the best fishing in South Carolina. Can't wait to come back.
A screen porch features a dining table with chairs, framed by soft lighting from hanging bulbs. The floor is painted blue, complementing the yellow walls. A window provides a view of the surrounding landscape, creating a serene setting for relaxation.
Cottage in Manning
4.74 out of 5 average rating, 136 reviews

A Great Lake house. Near Manning, SC and I-95.

GregRating, 5 stars3 weeks ago
Stayed at Ben's place for a fishing tourney. Everything was great and it was just what we needed. Price was great.
Guest favorite
A charming cottage is framed by lush greenery, featuring a white exterior and a welcoming front porch. An American flag hangs from the porch, and potted plants add a touch of color. The structure is surrounded by a well-maintained lawn, giving it a serene appearance.
Cottage in Kingstree
4.85 out of 5 average rating, 68 reviews

Lovely Lavender Cottage

Kyle And KellyRating, 5 stars1 week ago
We and our dog Sammie absolutely loved our stay! The beautiful and peaceful farmhouse was exactly as listed—spotlessly clean and fully equipped with everything we needed. It was so relaxing watching all the animals around the property. The host was quick to respond to any questions, and both they and the handyman were incredibly friendly and helpful. Highly recommend!

Quick stats about vacation rentals with lake access in Santee

  • Total rentals

    20 properties

  • Nightly prices starting at

    ﺩ.ﺇ367 before taxes and fees

  • Total number of reviews

    40 reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Rentals with a pool

    10 properties have a pool

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

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