Apartment vacation rentals in Santee

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Top-rated apartment rentals in Santee

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Guest favorite
A well-lit bedroom features a black metal bed frame holding a neatly arranged bed with white linens and decorative pillows. Two bedside tables with lamps are positioned on either side of the bed. Soft beige walls and a floral artwork enhance the calming atmosphere.
Apartment in Earlewood
4.93 out of 5 average rating, 241 reviews

Cozy 1BR Near USC & Riverbanks

Everything will be within your reach when you stay at this centrally located duplex located in the historic Earlewood neighborhood. Walking distance to beautiful Earlewood Park. A short drive to Segra Park (1.4 mi), downtown (2.1 mi), Columbia Canal & Riverfront Park (2.3 mi), Convention Ctr (2.4 mi), USC (2.5 mi), Publix Super Market (2.7 mi), Colonial Life Arena (2.7 mi), Riverbanks Zoo & Garden (3.1 mi), Five Points (3.3 mi), Saluda Riverwalk (3.3 mi), Ft Jackson (8.5 mi). Quiet neighborhood.

Guest favorite
A spacious studio room features a comfortable king bed with a patterned duvet and decorative pillows. A cozy seating area includes a wooden chair and a small side table. Two large windows provide natural light, enhancing the neutral tones of the decor.
Apartment in Columbia
4.91 out of 5 average rating, 145 reviews

*Tuscan Sun KING suite downtown FREE parking*

Perfectly situated in the heart of downtown! This studio is within walking distance of Main Street, The State House, USC campus and just a short drive to Williams Brice Stadium, Colonial Life Arena, medical facilities and so much more. The perfect stay for both long and short term guests. Wake up from a great night's sleep in our comfy KING bed to explore downtown, head out to see the Gamecocks play, or just sleep in! You’ll love staying at this stylish apartment! Permit No. STRN-004218-10-2023

Top guest favorite
A wooden serving board displays a freshly sliced loaf of banana bread, positioned in the foreground. In the background, a spacious bed is visible alongside a cozy seating area, featuring a green couch and a comfortable chair, both complemented by natural light streaming through the windows.
Apartment in Columbia
4.99 out of 5 average rating, 134 reviews

The Studio in Forest Acres

A calm, stylish space, filled with sunlight - the Studio is a detached 2'nd floor apartment, nestled in the heart of Forest Acres... SC's best kept secret! Take a relaxing walk around our beautiful old neighborhood and find delicious eats at highly-rated restaurants, groceries, dessert shops and local cafes. Just minutes from Columbia's storied cultural/musical nightlife, USC, the Koger Center for the Arts, Fort Jackson, Main St., and The Vista! (Age limit: must be at least 23 y/o to book).

Guest favorite
A welcoming living area features a comfortable blue sectional sofa adorned with colorful pillows. A round coffee table sits in front, while a cozy armchair provides additional seating. A modern ceiling fan and a fireplace enhance the space, complemented by natural light from the nearby window.
Apartment in North Charleston
4.92 out of 5 average rating, 117 reviews

N Charleston Home Close to Downtown - Pets Welcome

Need a weekend getaway? We’ve got you covered with our 2BR townhome! ✅ $0 cleaning fee + professionally cleaned 👜 Free early luggage drop-off + early check-in when available 📍 20 mins to downtown CHS 🏖️ Beach day? You’re only 45 minutes away! ✈️ 10 mins from CHS airport 🏊‍♂️ Pool access available 🚶‍♀️ Safe & walkable neighborhood 👑 Comfy king bed 🌳 Fenced backyard 🐶 Pet friendly 🧹 Chore-free checkout Book with confidence~ easy cancellation policy — 100% refund within 5 days!

Top guest favorite
A spacious bed is centered against a light-colored wall, adorned with neutral-toned decorative pillows and a textured throw blanket. The bedside tables hold soft lamps, casting a gentle glow, while a piece of abstract art adds a touch of sophistication above the bed.
Apartment in Columbia
4.94 out of 5 average rating, 120 reviews

Cozy 2 BD near USC&Ft Jackson 48

Be close to everything in this centrally located duplex. Walking distance to grocery store and restaurants. Short drive to Five Points (1.5 mi), the Vista (2.5 mi), USC 2 (mi), Ft Jackson (3 mi). Newly renovated unit has 2 bedrooms, 1 bath, a full kitchen (with single cup coffee maker and starter coffee supplies), washer & dryer. 1 king bed & 1 queen. Smart TVs in both bedrooms & the living room. Off street parking for 2 cars. Larger groups - ask about renting the unit next door too.

Guest favorite
A one-story red brick building is presented with a neatly manicured lawn and bordered by small, well-maintained shrubs. Large windows are visible, allowing natural light to brighten the interior. A concrete driveway leads to the entrance, flanked by steps that lead to the front door.
Apartment in Lake City
4.91 out of 5 average rating, 253 reviews

#4 Away from Home, Upgrade the Space, Not the Rate

Located on Main Street in a family home that has been updated to be like brand new. Apartment 4 has one bedroom with door, a private entrance, bath and dressing area, micro-kitchen, living & dining combination. Amenities include SPECTRUM & ROKU TV, in B.R. and L.R., wifi, front door parking, in room fresh brewed coffee (Cafe Valet) and Wind River Salon Products. Downtown Lake City is an easy one mile walk along Main Street. 1/2 way from New York to Miami. Hablamos Espanol.

Top guest favorite
The exterior of the property features a charming house with a light-colored façade and a green metal roof. A gravel driveway leads to the entrance, illuminated by soft outdoor lighting. Lush greenery surrounds the home, creating a serene and welcoming environment.
Apartment in Camden
4.95 out of 5 average rating, 310 reviews

Camden Carriage House on the Polo Field

This quaint and private one bedroom apartment is uniquely situated on a beautiful property surrounded by gardens, ponds and history. Camden is known for its Antebellum homes and from this location you can walk to some of its finest examples. The apartment is cozy with a comfortable queen size bed, a bathroom which features natural hardwoods and a claw-foot tub/shower and a modern Mitsubishi ductless heating and cooling system. Private deck overlooks historic polo field.

Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 136 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Guest favorite
A compact bedroom features a dark headboard with multiple decorative pillows arranged on a full bed, topped with a patterned comforter. Two small nightstands with lamps flank the bed, while wall decorations add visual interest. A window allows natural light to fill the space.
Apartment in Columbia
4.96 out of 5 average rating, 305 reviews

Charming and Cozy Studio Apartment over Garage

Cozy garage apartment with a private entrance and a small patio area in a nice, quiet neighborhood. The space is fully furnished with a full kitchen and living area. The apartment is near a neighborhood town center with shopping and restaurants.There are also some recreation areas around such as hiking trails, parks, and a YMCA. The apartment is located behind the host home, so guests are permitted to park one car at the bottom of the driveway.

Guest favorite
A charming brick exterior features a welcoming entrance with steps leading to a covered porch adorned with plants. Large windows allow natural light to brighten the interior. Surrounding greenery provides a tranquil setting in a peaceful residential neighborhood.
Apartment in Earlewood
4.93 out of 5 average rating, 297 reviews

The Toad Abode Studio

Relax and unwind in this cozy, centrally located studio. Perfect for travelers, the space features a comfortable double bed, work desk, cozy reading chair, and TV for your downtime. The kitchenette area includes a microwave & mini fridge with ample coffee & tea supplies, while the bright bathroom offers plenty of natural light. All the essentials you need for a comfortable stay. **Checkout on a Monday for more options at a discounted Sunday rate.

Guest favorite
A spacious living area is depicted, featuring a comfortable couch adorned with cushions, a wooden coffee table, and a flat-screen TV. Natural light streams through the wooden-blind-covered windows, casting soft shadows on the warm wooden floor and exposed brick wall.
Apartment in Arsenal Hill
4.94 out of 5 average rating, 174 reviews

Apartment in heart of Columbia

This NEWLY RENOVATED apartment in the heart of Columbia's Vista neighborhood is the perfect spot for your stay. Bright and spacious with a comfortable queen-sized bedroom with flat-screen smart TV; large and spacious living area with full kitchen and big screen smart TV, AND a super comfortable couch that can be used as second bed. Located in the heart of The Vista, you'll have access to scores of restaurants, bars, and retail. Plenty of parking!

Guest favorite
A bright kitchen features wooden countertops and white cabinetry. A dual sink is positioned under a decorative light fixture with hanging bulbs. Wall-mounted shelves display plants and kitchen essentials. Mirrors are framed above the bar area, enhancing light and space.
Apartment in Summerville
4.91 out of 5 average rating, 217 reviews

Full Kitchen, 2 Bed, 2 Bath W/ Laundry & Fish Pond

Hosted by a Superhost with multiple listings in Summerville, this charming, two bedroom, two bathroom apartment features a full kitchen, a washer/dryer combo, and a picturesque 1 acre fishing pond. Resting on a small farm on the outskirts of Summerville, this one-of-a-kind shabby-chic suite will have you in a southern state of mind in no time. Just don't be surprised if you see a chicken or two running around...

Popular amenities for Santee apartment rentals

Quick stats about apartment rentals in Santee

  • Total vacation rentals

    Explore 10 vacation rentals in Santee

  • Nightly prices starting at

    Santee vacation rentals start at ﺩ.ﺇ551 per night before taxes and fees

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Santee vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santee rentals