Private suite vacation rentals in La Mesa

Find and book unique private suite rentals on Airbnb

Quick stats about private suite rentals in La Mesa

  • Total vacation rentals

    Explore 30 vacation rentals in La Mesa

  • Nightly prices starting at

    La Mesa vacation rentals start at ﺩ.ﺇ 220 per night before taxes and fees

  • Verified guest reviews

    Over 4,920 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    30 of La Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across La Mesa rentals

  • 4.9 Average rating

    La Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Top-rated private suite rentals in La Mesa

Guests agree: these private suite rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A bright and airy living space features a cozy seating area with a gray sofa accented by blue and yellow cushions. A spacious bed is dressed in a patterned coverlet, positioned near a window with natural light illuminating the room. A small table adds functionality.
Guest suite in San Diego
4.96 out of 5 average rating, 213 reviews

Private, bright, cozy getaway with full kitchen

Experience a delightful getaway in this beautifully remodeled and centrally located guest suite. With its bright and inviting living space, it’s perfect for relaxation during the day and transforms into a cozy retreat at night. Sleeps up to four guests, the sofa easily converts into a full bed. Just 10-20 minutes from landmarks such as SDSU, Downtown, Little Italy, Gaslamp, San Diego Zoo, SeaWorld, Mission Bay, and concert venues. This is a 2nd floor unit, so guests will need to navigate stairs

Top guest favorite
A spacious sleeping area is featured, highlighted by a plush green bedspread atop a comfortable bed. Flanking lamps on either side provide soft illumination, while a large round mirror reflects the room's light. Decorative artwork and potted plants add a serene touch.
Guest suite in La Mesa
4.99 out of 5 average rating, 178 reviews

Emerald Suite Spa Experience with Sauna & Desk

Soothe your senses and unwind in your private spa retreat, featuring a restorative sauna, a huge soaking tub, and the refreshing scent of eucalyptus aromatherapy. Sink into a luxuriously comfortable king bed, surrounded by a calming ambiance. Thoughtful touches like plush robes and a chilled filtered water dispenser elevate your experience. Set in a tranquil neighborhood with easy access to San Diego’s highlights, this sanctuary offers the perfect blend of relaxation, rejuvenation, and comfort.

Guest favorite
A comfortable armchair with an ornate design is positioned near a glass door, allowing natural light to illuminate the space. An arched wall leads to the sleeping area featuring a spacious bed and decorative elements. Soft curtains frame the door, enhancing the serene atmosphere.
Guest suite in Spring Valley
4.81 out of 5 average rating, 339 reviews

Comfy Mountain Top Casita

Experience a one-of-a-kind getaway at our quite mountain retreat that offers a nice space and comfort for your family. Our 2-bedroom suite features 2 queen beds and a full futon, connected by a garden door living room and a beautiful arched wall, offering much more privacy than typical hotel rooms. Enjoy your own private entry and custom bath, complete with a well-equipped kitchen, outdoor barbecue, and dining area. Plus, with a washer/dryer on site and free parking. Create memories. Book Now!

Guest favorite
Guest suite in La Mesa
4.89 out of 5 average rating, 99 reviews

Breathtaking Views | Hot Tub & Cloud-King Bed #3

✨ Unforgettable views ✨ Sleep-on-a-cloud king bed ✨ Hot tub & lush gardens ✨ Spa-like bathroom ✨ Romantic & peaceful Perched high above the city on Mt. Helix, this elegant retreat is the perfect place to slow down and recharge. Enjoy breathtaking views, incredible sleep, peaceful gardens, and a hot tub beneath the stars. Guests describe their stay as magical, relaxing, and difficult to leave. Wake to hummingbirds, wander among the gardens, and discover your own private oasis above San Diego.

Top guest favorite
Guest suite in San Diego
4.98 out of 5 average rating, 128 reviews

Aloha Private Suite | Central Location!

Welcome to the Aloha Private Suite, a tropical inspired stay in the heart of San Diego. This bright, ocean inspired private guest suite features a private entrance, a comfy queen bed, and a relaxed island feel. Centrally located 15 minutes from the airport and beaches, and close to the stadium and San Diego’s main neighborhoods. Whether you are visiting the city, heading to the beach, or looking for a quiet place to unwind, the Aloha Private Suite offers a comfortable and convenient stay.

Guest favorite
An open kitchen and living area is shown, featuring a modern design with white cabinetry and wooden accents. A comfortable sofa is positioned in front of a wall-mounted TV. A dining table with seating for four is placed next to the kitchen, surrounded by natural light.
Guest suite in La Mesa
4.88 out of 5 average rating, 208 reviews

Stylish Boho Studio | Walk to Cafes | Outdoor Livi

The studio is located within a quiet leafy neighborhood right in the heart of La Mesa giving you a great base to explore everything San Diego has to offer. Inside you will find a bright, sun-filled space with a chic kitchen, an open plan living/dining area with a comfortable sofa bed, a stylish queen bedroom and a modern, sparkling bathroom with a built in laundry. Stay a short 15 min walk to a shopping center nearby with cafes, restaurants and stores and an easy 15 min drive into Downtown.

Top guest favorite
A swimming pool reflects sunlight under a clear blue sky, surrounded by a patio area. A colorful hammock is suspended near the pool, while potted plants add greenery. The adjoining building features large windows and a seating area.
Guest suite in La Mesa
4.94 out of 5 average rating, 209 reviews

Hacienda de Las Campanas

Stay in classic, historic California Hacienda style! A complete, self-contained apartment--your casita--within our beautiful, historic Monterey Spanish Revival hacienda home, situated on a half acre. The apartment has a separate, private entrance and includes a sunlit living/dining room opening on to a large swimming pool; a small kitchenette; and a private bedroom and bathroom down your own hallway. The suite is tastefully furnished consistently with the historic Spanish architecture.

Guest favorite
The exterior of the guest house showcases a clear blue sky and well-maintained landscaping. A spacious driveway leads to a two-car garage below, with a set of stairs ascending to the main residence. Palm trees provide shade and greenery to the inviting setting.
Guest suite in La Mesa
4.9 out of 5 average rating, 147 reviews

Private & cozy getaway 8min from downtown SD

One bedroom guest house in La Mesa/San Diego with private entry. Also, have an inflatable queen air mattress for another 1-2 sleepers. The two rooms are divided and can be separated with a sliding door and blackout curtains. You got all the basic amenities that you would need such as a mini fridge, keurig coffee maker, smart TV, central heat & AC. Prime location! Only 8 minutes from downtown SD. Come enjoy a memorable stay that has easy access to nearby beaches, nightlife and shopping.

Top guest favorite
A cozy sleeping area features a queen bed with blue and white striped linens. A decorative throw pillow with the word 'relax' is positioned at the center. A side table and a reclining loveseat are present, with wall decor enhancing the serene ambiance.
Guest suite in El Cajon
4.97 out of 5 average rating, 136 reviews

California Dreamin’ at our Coastal-Inspired Suite

Take a break and unwind at our coastal-inspired oasis. Enjoy a relaxed cabana vibe with great natural light in a quiet neighborhood. This newly built private suite has all new appliances, furniture, and fixtures. You'll have everything you need to make you feel right at home with a fully functioning kitchen, en-suite bathroom and stacked washer/dryer. It includes a comfortable workspace with charging ports & a reclining loveseat along with a brand new gel memory foam queen bed.

Superhost
A compact kitchenette features cream-colored cabinetry complemented by a vibrant blue countertop. Appliances include a microwave and refrigerator, with cooking utensils and dishware neatly arranged on the open shelves above. A flat-screen TV is mounted on the wall, enhancing the functional space.
Guest suite in Lemon Grove
4.87 out of 5 average rating, 283 reviews

GROVE CASITA/ Amiable Room, Private Enrty, Bath

Quaint Guest Space - 2 easy, fast access ways to Freeway - Keypad entry - Parking - AIR CONDITIONING, - Wired internet, Wi-Fi - Laundry - 10 to 15 minutes to downtown San Diego, the Convention Center, Little Italy, and 32nd Naval Base, San Diego Zoo/ Balboa Park, Coronado Island beach - 15 to 20 minutes to Sea World, Tijuana Mexico, La Jolla, Imperial Beach, Ocean Beach - 1.6 miles to Trolley - 0.6 miles to bus Bus lines - Close to Grocery Stores , fast food, and restaurants

Top guest favorite
A bright studio space features a spacious bed adorned with a patterned blanket, complemented by decorative pillows. Natural light floods in through two windows with sheer curtains. A cozy seating area includes a wicker chair and a small rug, enhancing the room's inviting ambiance.
Guest suite in La Mesa
4.96 out of 5 average rating, 238 reviews

La Mesa Garden Suite

Welcome to our newly remodeled La Mesa Garden Suite - the perfect destination for your San Diego vacation! Nestled beneath a main residence in a lush backyard, this tranquil downstairs unit offers the perfect blend of privacy and convenience. Our Airbnb has its own private entrance, patio, and full bathroom. Send us a message if you have questions about our Airbnb availability. We try to accommodate as best we can. If you need anything during your stay don't hesitate to ask!

Top guest favorite
A spacious living area features comfortable reclining chairs and a neutral-colored rug. A wooden bookshelf filled with books and decorative items is visible to the right. A kitchen island with modern appliances is located in the background, illuminated by natural light from multiple windows.
Guest suite in Santee
4.95 out of 5 average rating, 102 reviews

Hidden Gem 2 bedroom sleeps 8 family friendly

Enjoy our centrally-located place. 1700 sq ft 2 story, 2 bed 2.5-ba, gated, Secluded, Less than a mile walk/drive to the trolley station 25 min to Beaches. Living/dining area with 48”TV, Fully equipped kitchen, laundry/bathroom, luxurious master bedroom suite, has private entrance, large on-suite bath with extra-large soaking tub. Upstairs spacious room; has a full bath - dual purpose- Entertainment sleeping area includes 75" TV, 2 queen bed, single bunk, & work space

Popular amenities for La Mesa private suite rentals

When is the best time to visit La Mesa?

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Avg. priceﺩ.ﺇ 415ﺩ.ﺇ 426ﺩ.ﺇ 400ﺩ.ﺇ 419ﺩ.ﺇ 430ﺩ.ﺇ 463ﺩ.ﺇ 437ﺩ.ﺇ 437ﺩ.ﺇ 400ﺩ.ﺇ 408ﺩ.ﺇ 408ﺩ.ﺇ 393
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