Vacation rentals in La Mesa

4.99 out of 5 average rating, 115 reviews

Private 1 BR Paradise retreat

Private, yet central. It is your exclusive paradise retreat to enjoy from your spacious 1 bedroom guest house located on the lower level of our home. Hang out in the expansive and private backyard with pool, different sitting areas and covered BBQ room. Or maybe a workout in the gym. Centrally located in the Village of La mesa. Just a 1/4 mile jaunt into the quaint village with its numerous assortments of dining options, stores and trolley station. Freeway close to beaches, downtown and airport

4.89 out of 5 average rating, 367 reviews

Anna's Historic Stone Cottage w/panoramic View!

Welcome to Anna's Historic Stone Cottage! The 110 year old cottage has been transformed into the perfect combination of romantic and rustic for a dream-worthy getaway. The 280sq ft cottage features stunning, panoramic views of the San Diego skyline while offering rooftop seating for sunrise and sunset viewing. The Cottage is conveniently located 20 minutes from the world famous San Diego zoo and most other must-see, tourist spots. Amenities for special occasions offered too. Check out our menu!

4.99 out of 5 average rating, 108 reviews

Guest suite in La Mesa

Emerald Suite Spa Experience with Sauna & Desk

Soothe your senses and unwind in your private spa retreat, featuring a restorative sauna, a huge soaking tub, and the refreshing scent of eucalyptus aromatherapy. Sink into a luxuriously comfortable king bed, surrounded by a calming ambiance. Thoughtful touches like plush robes and a chilled filtered water dispenser elevate your experience. Set in a tranquil neighborhood with easy access to San Diego’s highlights, this sanctuary offers the perfect blend of relaxation, rejuvenation, and comfort.

4.99 out of 5 average rating, 208 reviews

Guest suite in La Mesa

"NEW" SWEET AND COZY CACTUSVILLE STUDIO SAN DIEGO

Listing sleeps up to 4 guest. After third or fourth person an extra fee of $15. dollars per person, per night will be charged, comfortable, private studio in a great neighborhood in La Mesa. Freeway close to SDSU and the heart of downtown San Diego. Some local attractions are Sea Port Village, the world famous San Diego Zoo, Sea World, Balboa Park and much more. You may also want to see Downtown La Mesa, an 8 minute drive where there are restaurants, bars, antique shops and more to explore.

4.93 out of 5 average rating, 163 reviews

Granny Flat with Bedroom/Bathroom/Kitchen

My place is family friendly, close to comic con, , restaurants and dining, , the beach, , family-friendly activities , public transportation (trolley). You’ll love my place because of the peace and quiet. It's very quiet and private. PLEASE DO NOT BOOK IF YOU ARE PLANNING ON PARTYING. THIS IS NOT APPROPRIATE FOR MORE THAN 2 PEOPLE. There is a private entrance that you may use once you meet us.. We like to meet all our guests first and then you may come and go as needed. NO SMOKING NO PETS

4.99 out of 5 average rating, 188 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

Superhost

4.86 out of 5 average rating, 221 reviews

Newer "Manor Studio"

Centrally located in San Diego County this newer studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

4.99 out of 5 average rating, 246 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Superhost

Guest suite in La Mesa

4.9 out of 5 average rating, 134 reviews

Private & cozy getaway 8min from downtown SD

One bedroom guest house in La Mesa/San Diego with private entry. Also, have an inflatable queen air mattress for another 1-2 sleepers. The two rooms are divided and can be separated with a sliding door and blackout curtains. You got all the basic amenities that you would need such as a mini fridge, keurig coffee maker, smart TV, central heat & AC. Prime location! Only 8 minutes from downtown SD. Come enjoy a memorable stay that has easy access to nearby beaches, nightlife and shopping.

4.98 out of 5 average rating, 154 reviews

Apartment in La Mesa

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

4.96 out of 5 average rating, 180 reviews

Mountain top view getaway loft

This loft is completely sound proof! VIEWS, VIEWS, VIEWS!! Do not miss this stunning contemporary loft, located in the highly desired Mt. Helix community. The guest house faces west, giving you phenomenal 270-degree views of the ocean, Downtown, Point Loma, Coronado islands, Coronado bridge, and more! Designed and built by an acclaimed San Diego home designer, this property was featured in Dream Homes Magazine and is well known for its incredible design and construction.

4.99 out of 5 average rating, 279 reviews

Spacious, private Mt. Helix country style studio

Located in a quiet and lush neighborhood, in hills of La Mesa. This private studio has everything you need to relax and experience the California life: comfy queen size bed, full kitchen, patio, bbq, and fire pit. Within walking distance to Mt. Helix Historic Park for a spectacular 365-degree view of San Diego. You are 20 minutes from the beach, airport, and mountains.

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Popular amenities for La Mesa vacation rentals

Self check-in

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Other great vacation rentals in La Mesa

5 out of 5 average rating, 67 reviews

Shadow House Mt. Helix

AlexisRating, 5 stars1 week ago

Had a great stay! The place is very cozy and comfortable. Love that it’s tucked away in a a quaint private neighborhood. The place was beautiful and would definitely stay again!

4.97 out of 5 average rating, 88 reviews

Cozy, Single Bedroom, Detached Guest House

AngelaRating, 5 stars2 weeks ago

We had a wonderful stay at Jack and Taylor’s! The space was clean and incredibly comfortable, and the overall ambiance of the home was cozy and relaxing. Highly recommend it to anyone looking to unwind.

4.99 out of 5 average rating, 80 reviews

Escape to tranquility: the perfect retreat

AgnieszkaRating, 5 stars2 weeks ago

Linda and Bill’s place was a wonderful surprise. It is tucked away in a peaceful nook of the well established La Mesa community. It is our second reservation here and we hope to be back. The owners are super friendly and responsive. Everything was like described, even better in real life ;) there are stairs to the unit, but this is clearly described in the listing.

5 out of 5 average rating, 46 reviews

Private Sunlit Surf Shack

BrendaRating, 5 stars3 weeks ago

This place is close to everything. It’s close to downtown San Diego, Little Italy, and all tourist attractions. I’ve been to San Diego many times and this place is literally just right off the freeway. I’d stay at this place again.

5 out of 5 average rating, 16 reviews

The Coral House-Luxury 1BR 1BA-Fire Pit+Grill+EV

DamienRating, 5 stars2 weeks ago

This is by far one of the best Airbnb experiences I have ever had. Ricardo curated an experience from the decor to the quality of the sheets to the patio to the wash and dryer. No stone was left unturned…20/10

5 out of 5 average rating, 97 reviews

Tiny home in La Mesa

The Tiny Helix

JoaquinRating, 5 stars2 weeks ago

I had a wonderful stay at Tooraj’s place! The location was absolutely beautiful with stunning views that made every morning and evening special. The space itself was spotless — very clean and well-maintained, which made it feel comfortable and welcoming. Tooraj was a great host, attentive and easy to communicate with. I would definitely recommend this place to anyone looking for a peaceful and scenic getaway!

4.96 out of 5 average rating, 23 reviews

Tiny home in La Mesa

Terracotta Casita

CarlosRating, 5 stars1 week ago

I highly recommend staying here if you’re ever in San Diego!!! Jose and Roseanne are wonderful hosts, they communicate clearly and are very accommodating. The place is spacious, very nice, and conveniently located not too far from the main attractions. We loved our stay!