
Family-friendly vacation rentals in La Mesa
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in La Mesa
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Private 1 BR Paradise retreat
Private, yet central. It is your exclusive paradise retreat to enjoy from your spacious 1 bedroom guest house located on the lower level of our home. Hang out in the expansive and private backyard with pool, different sitting areas and covered BBQ room. Or maybe a workout in the gym. Centrally located in the Village of La mesa. Just a 1/4 mile jaunt into the quaint village with its numerous assortments of dining options, stores and trolley station. Freeway close to beaches, downtown and airport

Townhouse - Private Yard, La Mesa Village
Enjoy a stylish experience at this centrally-located studio. Walking distance to La Mesa Village, where you can enjoy restaurants, coffee shops, boutiques, & more. With all the things you need in a kitchen to whip up any meal, and a patio to enjoy the San Diego sun. Hop on the trolley to get to anywhere. Bringing more friends or family along with you? We also have another listing, Casa de Pueblo at the same property. 20 min drive to the Beach or Downtown 15 min drive to Balboa Park or Old Town

Hidden King Suite with Garden, Parking - 4 Guest
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

Stunning Guest House 15 min. from Zoo, Downtown
Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Private & cozy getaway 8min from downtown SD
One bedroom guest house in La Mesa/San Diego with private entry. Also, have an inflatable queen air mattress for another 1-2 sleepers. The two rooms are divided and can be separated with a sliding door and blackout curtains. You got all the basic amenities that you would need such as a mini fridge, keurig coffee maker, smart TV, central heat & AC. Prime location! Only 8 minutes from downtown SD. Come enjoy a memorable stay that has easy access to nearby beaches, nightlife and shopping.

“Pineapple Express”
Aloha! If your looking for a relaxing & mellow vibe, We invite you to stay the night in our cozy 1948 16ft Travelo travel trailer, “The Pineapple Express” Enjoy your private pool and hot tub, behold a beautiful San Diego sunset from the hillside deck or pull up a stool at the Tiki Bar for your morning coffee. We now have an outdoor gas grill, hot water pitcher, microwave, mini fridge and utility sink for food prep! Hablamos español Deaf friendly 🏳️🌈. Alycen ASL fluent.

Tranquil Poolside Studio
Quiet Poolside Studio Suite! Perfect for visiting family in La Mesa or enjoying everything San Diego has to offer! Please note: this is not a party house. Private side entrance to a relaxing poolside studio. Very quiet with TV, and full kitchen. Comfortable queen size bed and sofa that can sleep one more person comfortably. We are 20 min to the beach, or relax and enjoy the pool! Close to SDSU and easy freeway access to anywhere in San Diego.

NEW! Valley View Garden Suite
Kick back, relax, and enjoy the view in this delightful, 1 bedroom w/ livingroom suite. 20 mins from beaches, downtown, Sea World, Zoo. 2 mi to Grossmont Hosp, 8 mi to SDSU, 3 mi to Gillespie Field The suite is attached on the side of a house. But it is completely separate and has its own private entrance. The back patio & side breezeway are just for you . Free, reserved, off-street parking.

The Witch’s Inn
Ready to escape the boring San Diego sunshine and pretend you’re in the wizarding world for the night? This magical nook is perfect for those wishing to celebrate a special occasion, have a fantasy movie marathon, or just escape the muggle world for a little while. Outside you’ll find stunning sunset views and a 40 foot wide (almost finished) mural of Diagon Alley to complete your experience!

Private Studio with a Panoramic View
Escape to Your Hilltop Retreat! Relax in secluded studio. Sip wine by the cozy fire pit or unwind on the patio with a bird’s-eye view. Conveniently located just 15-20 minutes from the beach and downtown, you’re never far from the action. Plus, well-behaved pets are always welcome. Bringing more friends or family along with you? We also have another listing, The Eagles Nest at the same property.

La Mesa Suite
Mi mesa es su mesa, a beautiful newly built home in sunny La Mesa. Easy access to centrally located shopping center, SDSU and up and coming downtown La Mesa. Short drive down the 8 freeway to the mission beach and downtown SD. Includes everything you need in your home away from home while also providing comfort, security and privacy.
Popular amenities for La Mesa family-friendly rentals
Family-friendly home rentals with a hot tub

Pool Side Safari Cabin (On Backside of our Home)

Mountain View Retreat in Gated Estate (Hot Tub)

Comfy Mountain Top Casita

Da Hui Hut - La Mesa’s best view and spa

The Outside Inn at The Tipsy Goat Ranch

Views•Sauna•SoakTub•Firepit+Zoo pkg add-on

Zen Airstream Experience

Private Luxurious Rooftop Deck & Private Jacuzzi.
Family- and pet-friendly home rentals

Insta-worthy! 1 night/many nights, no min required

Lemon Drop Cozy Studio

Fletcher Hills - modern 1 BR.Easy, no step access.

🤲🏼 Handmade hideaway Mt. Helix - AC/Laundry/Parking

Hacienda de las Campanas (Bell Hacienda)

Private cozy cottage

The Tiny Helix

Kensington Classic/Historic Tudor - Fully Licensed
Family-friendly home rentals with a pool

Mountain Retreat Ocean View-Great for Staycation

The Queen House

The BEST NEST Clean, peaceful, private, affordable

Private Poolside Cabana

Former ManCave with Pool & Spa!

Comfortable & convenient accommodation @ San Diego

Designer Luxury Rental With Pool

Noonan's Nest
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | 
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ738 | ﺩ.ﺇ742 | ﺩ.ﺇ764 | ﺩ.ﺇ804 | ﺩ.ﺇ826 | ﺩ.ﺇ918 | ﺩ.ﺇ940 | ﺩ.ﺇ881 | ﺩ.ﺇ749 | ﺩ.ﺇ746 | ﺩ.ﺇ775 | ﺩ.ﺇ786 | 
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C | 
Quick stats about vacation rentals that are family-friendly in La Mesa
 - Total vacation rentals- Explore 250 vacation rentals in La Mesa 
 - Nightly prices starting at- La Mesa vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees 
 - Verified guest reviews- Over 12,020 verified reviews to help you choose 
 - Pet-friendly vacation rentals- Find 110 rentals that welcome pets 
 - Vacation rentals with a pool- 80 properties feature pools 
 - Rentals with dedicated workspaces- 180 properties have a dedicated workspace 
 - Wi-Fi availability- 250 of La Mesa vacation rentals include wi-fi access 
 - Popular amenities for guests- Guests love Kitchen, Wifi, and Pool across La Mesa rentals 
 - 4.8 Average rating- La Mesa stays are highly rated by guests—averaging 4.8 out of 5! 
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