
House vacation rentals in La Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in La Mesa

Total vacation rentals
Explore 320 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at ﺩ.ﺇ 110 per night before taxes and fees

Verified guest reviews
Over 14,030 verified reviews to help you choose

Family-friendly vacation rentals
210 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 110 rentals that welcome pets

Vacation rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
190 properties have a dedicated workspace

Wi-Fi availability
320 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness, and more.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

Family Pool Retreat + Gym, Fire Pits, Views (Sleep
Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, it’s perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! 🌅🏠 We have 3 comfy beds that can

[1,888 SF] Casa De Rosas: Spacious home near SDSU
Welcome to Casa de Rosas! Enjoy your stay at our spacious house at the front of a cul-de-sac nestled in La Mesa. Perfect for being with friends and family. Walking distance to grocery store, coffee shops, local restaurants, and bars. Our 1,888 sq. ft. home has 3 full bedrooms, 1 hybrid bedroom with trundle beds , 2 full bathrooms, den stocked with games, foosball/ pool table, couch + pull out bed, working stations, and an open main living space. Outdoor space includes seating, fire pit & grill

2 Bed Hidden Oasis | Garden, Laundry, Parking
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

San Diego Pool | Fire Pit | Sunshine | Sleeps 10
Escape to a fresh 4-bedroom retreat for family and friends (10 ppl max). Updated in January of 2024 with new furniture, and fixtures. Bask in the sun on the deck, take a dip in the pool. Enjoy the private and fenced backyard, BBQ, or the recently renovated and modern Kitchen. This home is perfect for vacations or remote work. Explore San Diego beaches and all the area has to offer, the most popular tourist destinations are all within a 20-30 minute drive. 20 minutes to the beach! Book with us!

Classic Mid-Century Mount Helix Home with Views
Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Jamul Hacienda | Couples Retreat | Pool & Views!
The Casita retreat is a guesthouse situated among a private 20 acre oasis surrounded by majestic mountain views and a citrus grove 30-40 minutes from San Diego. The space is designed for nature enthusiasts to retreat from the daily hustle and bustle and find peace and slowness. Come take a pause, relax poolside, pick citrus (when in season), enjoy nearby trails, and wineries. The sunsets and starry skies are breathtaking. We hope you get to experience their magic for yourself.

Family Fun Oasis Pool Spa and Game Room
Exceptional home w/heated pool and spa in a quiet neighborhood; kitchen has everything you need and more! Perfect for families with kids of various ages or multiple families. What to Expect: - Heated pool w/safety cover - Hot tub - Game Room - Trampoline - Jungle gym - Baby/toddler supplies (pack N play/High Chair) - Spacious master suite. - 20 mins to the beach, the San Diego Zoo, Balboa Park, Sea World, Little Italy and downtown San Diego and all that it has to offer!

Palm Cottage, San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

Spanish Casita w/ Hot Tub, Fire Pit, Private Yard
Welcome to Casa Stella, a beautifully renovated 1920s Spanish casita, just a 10 min drive from Balboa Park, San Diego Zoo, Downtown, and the beaches. Nestled on a quiet, picturesque street, this pet-friendly private home offers a serene stay while being just a 5-min walk to Adams Avenue's top restaurants, breweries, and yoga studios. Enjoy free parking, a cozy fire pit, and mid-century modern flair! We offer flexible check-in/ check-out, ask me how!
Popular amenities for La Mesa house rentals
House rentals with a pool

Views - Quiet Mt. Helix Home - Pool -Sleeps 11

The Queen House

Entertainers Dream Pool Home

San Diego Oasis: Private Pool & Sunny Escape!

Bright and spacious home with views, pool & spa.

Stunning 2BR/2BA| Plunge Pool, AC, Private

Modern Hilltop Home: Roomy, Views, Family-Friendly

Upscale Resort House /Views, Saltwater Pool/Spa !
Weekly house rentals

Escape to tranquility: the perfect retreat

Contemporary Luxury Retreat

Relaxing, 4BD, 2 King Bed, w/ View & Hot Tub

HotTub & 100+ Game Arcade Family Getaway San Diego

La Mesa Retreat | Hot Tub | Fire Pit | Longer stay

Sunnyside Resort Spa, Beach, Zoo, Arcade

Peaceful Casita | Firepit • Near SDSU

Entire House, English garden, Private Driveway
Private house rentals

Tiny Home with a View

Sunset Summit by Coastline Vacation Rentals

Newly Updated & Beautiful 5 bed • 3 bath • Hot Tub

Helix Haven

Pool + Hot Tub, BBQ, Chef Kitchen, SDSU, San Diego

Newly Renovated 3BD 2BA Home | SDSU & Attractions

Downtown La Mesa gem

Family Hilltop Home w/ Views
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 679 | ﺩ.ﺇ 720 | ﺩ.ﺇ 786 | ﺩ.ﺇ 661 | ﺩ.ﺇ 676 | ﺩ.ﺇ 786 | ﺩ.ﺇ 918 | ﺩ.ﺇ 775 | ﺩ.ﺇ 679 | ﺩ.ﺇ 690 | ﺩ.ﺇ 720 | ﺩ.ﺇ 731 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
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- Rosarito Beach
- SeaWorld San Diego
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo Safari Park
- San Diego Zoo
- Petco Park
- San Diego Convention Center E Ent
- Balboa Park
- Tijuana Beach
- Pacific Beach
- Pechanga Resort Casino
- San Diego State University
- Torrey Pines State Beach
- Anza-Borrego Desert State Park
- Oceanside City Beach
- Mission Beach
- Ocean Front Walk
- La Misión Beach
- Moonlight State Beach
- Las Olas Resort & Spa
- Belmont Park
- Sesame Place San Diego





