House vacation rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa house rentals
House rentals with a pool
Home in La Mesa
4.93 out of 5 average rating, 107 reviewsUpdated TownHome, Great Location, Fantastic Views
Jan 15 – 22
Home in La Mesa
4.81 out of 5 average rating, 133 reviewsSunny SD/La Mesa Updated '24-Pool-4 bed-Sleeps 10
Oct 20 – 27
Home in La Mesa
4.87 out of 5 average rating, 131 reviewsThe Queen House
Nov 23 – 30
Home in San Diego
5.0 out of 5 average rating, 140 reviewsMidcentury Lux 4BR home with Pool, Spa & Cabana
Feb 12 – 19
Home in San Diego
4.9 out of 5 average rating, 117 reviewsSan Diego Getaway W/Pool & Hot tub! Sleeps 8!
Apr 12 – 19
Home in San Diego
4.87 out of 5 average rating, 143 reviewsBright and spacious home with views, pool & spa.
Aug 18 – 25
Home in El Cajon
4.97 out of 5 average rating, 134 reviewsBeautiful 3,000 Sq Ft Tropical Oasis
Oct 4 – 11
Home in San Diego
4.98 out of 5 average rating, 240 reviewsResort Style Living with Pool, Spa, and Bay Views!
Oct 23 – 30
Weekly house rentals
Home in La Mesa
4.95 out of 5 average rating, 111 reviewsCheery & Roomy Family Home w/Master Suite, Fence
Oct 1 – 8
Home in San Diego
4.89 out of 5 average rating, 366 reviewsOcean Beach Close to all
Mar 25 – Apr 1
Home in San Diego
4.92 out of 5 average rating, 141 reviewsPrivate Studio
Jul 6 – 13
Home in La Mesa
4.88 out of 5 average rating, 177 reviewsPrivate cozy house
Jul 10 – 17
Home in San Diego
4.9 out of 5 average rating, 101 reviewsCozy 2Bed-Private Parking, Dog Friendly, Big Yard!
Jan 7 – 14
Home in San Diego
4.87 out of 5 average rating, 138 reviewsMarta's house, San Diego, Close Downtown, Garden
Sep 19 – 26
Home in La Mesa
4.83 out of 5 average rating, 121 reviewsLa Mesa's Tranquility
Aug 17 – 24
Home in Alpine
4.99 out of 5 average rating, 143 reviewsFully Fenced Alpine Property with Guest House
Feb 18 – 25
Private house rentals
Home in La Mesa
4.97 out of 5 average rating, 35 reviewsGarden Studio (40% long, 15% short term discount!)
Nov 8 – 15
Home in El Cajon
4.98 out of 5 average rating, 89 reviewsSuite Charles Way: A Cozy Fletcher Hills Studio
Aug 27 – Sep 3
Home in La Mesa
4.93 out of 5 average rating, 96 reviewsPalm Cottage San Diego
Oct 13 – 20
Home in El Cajon
5.0 out of 5 average rating, 7 reviewsCozy 1BR Home with Lovely Front Yard
Dec 22 – 29
Home in La Mesa
5.0 out of 5 average rating, 23 reviewsChic and Modern Luxury Private Guest House
Oct 22 – 29
Home in Spring Valley
4.87 out of 5 average rating, 15 reviewsIsabel's Private Studio
Sep 7 – 14
Home in La Mesa
4.9 out of 5 average rating, 20 reviewsWelcome to Our La Mesa Retreat
Aug 26 – Sep 2
Home in El Cajon
5.0 out of 5 average rating, 42 reviewsCharming 1BR Getaway
Oct 12 – 19
Quick stats about house rentals in La Mesa
Total rentals
280 properties
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Rentals with a pool
80 properties have a pool
Pet-friendly rentals
90 properties allow pets
Family-friendly rentals
190 properties are a good fit for families
Total number of reviews
9.5K reviews
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