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Villa vacation rentals in La Mesa

Find and book unique villas on Airbnb

Top-rated villa rentals in La Mesa

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Guest favorite
A modern kitchen features dark cabinetry and a large island with seating. Stainless steel appliances are integrated seamlessly, while natural light pours through multiple windows. A stylish chandelier hangs above the island, and artistic decor is arranged on the walls, adding character to the space.
Villa in Allied Gardens
4.92 out of 5 average rating, 25 reviews

Fun Get Away, Vaulted Ceiling, Pool, Hot Tub, New.

Enjoy a stylish experience at this centrally-located place. Great place to stay for those seeking an experience close to the beach and mountains and anywhere in San Diego you'd like to visit. 5 min from trails and Cowles Mountain. 15 min to Sea World, Animal Park, beaches, parks, downtown, Balboa park, the Midway museum, Coronado, Torrey Pines, La Jolla Cove, and much more! 2 min to a kid playground. Nice Villa in a really nice and Quiet Neighborhood, but will also accommodate your best party!

Top guest favorite
A private rooftop deck features a hot tub, seating area with lounge chairs, and a dining table. Scenic views of the harbor and city skyline are visible at dusk, with warm lights creating a peaceful ambiance. The space is surrounded by terracotta roof tiles.
Villa in San Diego
4.93 out of 5 average rating, 107 reviews

☆🏘 Breathtaking 180º Views 🏝Hot Tub🏝 5☆ Reviews

🏝Welcome to the Harbor View Villa! 🏘A 3,500sqft villa with 6 bedrooms, 4 bathrooms and a 800 sqft walk-out deck. Complete with private rooftop hot tub, backyard, outdoor & indoor living. 
With 180º private day & night views from almost anywhere in the house! Make yourself at home in our Mission-Style Villa with stunning views of the boats in the Harbor, Downtown lights, and Coronado Island! 🗺Ideal for kids Perfect for MCRD & PLNU graduations (5min). Ask about early checkin / late checkout

Guest favorite
A spacious outdoor area features a clear swimming pool surrounded by a patio. Lush palm trees and other greenery create a private atmosphere. A gazebo and dining seating area are visible, providing a relaxing space for gatherings and leisure.
Villa in Allied Gardens
4.91 out of 5 average rating, 103 reviews

6-bed Paradise Villa Pool, hot-tub massage chair

*EV charging available Welcome to Casa Cerro-my incredible chic high-tech modern villa in San Diego! This stylish place to stay is perfect for families and group trips. Its open and airy layout can accommodate up to 11 people. This completely remodeled home is furnished with all the luxuries of home and more that is powered by an iPad for you to use. I love technology. But don't worry you don't have to use it to power up the house, everything has traditional switches/remotes if you choose.

Guest favorite
A serene infinity pool is pictured, with a cascading waterfall creating a soothing sound. The water reflects shades of blue, merging with a vibrant sunset in the background. The landscape stretches out, providing breathtaking views of the distant horizon.
Villa in El Cajon
5 out of 5 average rating, 76 reviews

Zen Resort w Infinity Pool/Spa +360° Socal views

Relax, rejuvenate, & revive at your own hilltop paradise with no nearby neighbors and a private gated driveway. This hacienda offers a year round temp controlled Infinity edge pool & Spa complete with 360° views, outdoor fire-pit, custom tiki hut and a seamless indoor outdoor flow. Accommodation includes the main house, a charming casita, and an optional Airstream-sleeping 20+ guests in comfort. A perfect blend of seclusion, and resort-level amenities & just 15 min. from Downtown San Diego.

Superhost
Villa in Rolando
4.92 out of 5 average rating, 48 reviews

Stay&Play SDSU- Pool •HotTub •GameRoom •SunsetView

☀️Welcome to your luxurious San Diego getaway! ☀️ This spacious 5-bedroom, 2-bathroom 2-level home is perfect for groups and families. Dive into the sparkling blue pool, unwind in the 6-person hot tub, or relax in the cozy outdoor seating areas. Enjoy stunning views from the balcony overlooking the pool, perfect for sunsets. With a central location, plenty of space to relax, and a mix of comfort and elegance, this home is ideal for exploring or unwinding on your San Diego adventure!

Guest favorite
An inviting outdoor entertainment area features a heated saltwater pool surrounded by elegant lighting and stylish lounge furniture. Inflatable swan floats rest in the water, while vibrant umbrellas provide shade over seating. Lush landscaping enhances the serene environment, making it ideal for relaxation.
Villa in El Cajon
4.91 out of 5 average rating, 182 reviews

Enchanted Paradise! ♨ Pool+Spa+Outdoor Kitchen ☀

Brand New Property! Massive garden of Eden style resort home with sprawling outdoor entertainment area and spacious open concept inside, perfect for large families with kids and responsible adults. Updated top to bottom with all new outdoor and indoor furniture, modern upgrades in all bedrooms and common areas. Centrally located and 20 minutes from the beach and all of SD's top attractions! 8 person hot tub, sparkling gas heated saltwater pool and new outdoor kitchen. Don't miss out!

Superhost
Villa in Grant Hill
4.84 out of 5 average rating, 19 reviews

Pool/Spa, Min Downtown, Balboa, Zoo, Site Parking

Welcome to Leyla— a bright and spacious bottom apartment, 2 bed, 1 bath apartment. Enjoy an open concept living area, full kitchen, dining space, and a pullout couch for extra guests. Perfectly positioned near San Diego’s major attractions: 📍 Balboa Park – 1.0 mi 📍 Petco Park – 1.1 mi 📍 Gaslamp Quarter – 1.4 mi 📍 San Diego Zoo – 2.5 mi 📍 SD International Airport – 5.0 mi Modern, comfortable, and fully equipped for both short and extended stays. See below for more details:

Top guest favorite
A private pool is surrounded by a stone patio and lounge seating. The house features large windows and a covered dining area with a patio umbrella. Lush greenery complements the tranquil outdoor space, emphasizing the welcoming atmosphere of the backyard.
Villa in La Mesa
5 out of 5 average rating, 53 reviews

Casa Charles, Tropical backyard, Pool & Pizza oven

This beautiful family home is a entertainment paradise with a large gourmet kitchen with plenty of pots and pans, dished and kitchen ware, even the spices to cook up a delicious family dinner. but you'll be sure to enjoy the tropical backyard with a bocce court, that includes a pool, a hot tub, an outdoor wood fireplace, a gas fire pit and even a wood fire pizza oven - You're freeway close to everything San Diego has to offer when you stay at this centrally-located retreat.

Top guest favorite
A living area features a mix of seating options, including a blue sofa and a red chair. A wooden coffee table is positioned centrally. Floor-to-ceiling shelving holds a variety of books and DVDs. A dining area is visible, accompanied by natural light from nearby windows.
Villa in Mission Hills
4.98 out of 5 average rating, 92 reviews

Hidden Villa with Beautiful Furnished Garden Patio

Close to everything, quiet and private. This beautiful 2 Bd Villa seems to be loved by all who stay here. The outdoor private patio feels like your in the forest. Gorgeous custom bath with large marble shower. Full size laundry. Great entertainment system,DVD's, Roku, Amazon Prime. The home has open beam ceilings, lots of light and a fabulous patio fully furnished for guests, outdoor dining and barbecuing. The home is private, fenced, furry friends are welcome.

Top guest favorite
Villa in Jamul
4.96 out of 5 average rating, 84 reviews

@ Paradise villa, Top view, 4600sqrt on 10 acres

TOT #COSD-00749 Experience stunning 360-degree views from every corner of this spacious villa, which spans 4,600 square feet on 10-acre lot. This is the perfect place for family gatherings and celebrations. The house features five oversized bedrooms and four bathrooms. There is parking +30 cars. Enjoy a massive pool, deck, golf, chess, pool table, foosball, ping pong, Nintendo game, and screen projector. This truly one-of-a-kind property is not to be missed!

Guest favorite
The property displays a charming two-story building with arched balconies and a red-tiled roof. A spacious patio features vibrant outdoor furniture, including a large umbrella, providing shaded seating. The modern garage blends seamlessly with the structure, further enhancing the property's appeal.
Villa in Pacific Beach
4.93 out of 5 average rating, 148 reviews

The Crown Jewel Villa with AC!Bikes,Kayak and SUP!

Escape to the peaceful and coveted beach community of Crown Point in San Diego! This highly sought after neighborhood boasts mostly permanent residents, creating a serene and tranquil environment for our guests. Right across the street from the home, you can find Ski Beach and Park, a favorite spot for families and kids. Explore the variety of local eateries and coffee shops, or take a short walk to popular Sail Bay and the ocean.

Guest favorite
Villa in Spring Valley
4.96 out of 5 average rating, 90 reviews

Modern 3-Bedroom Villa, Luxurious Outdoor Oasis

Welcome to Your Perfect Spring Valley Villa! Nestled in the heart of Spring Valley, our charming spacious 3-bedroom, 2-bath home offers the perfect blend of comfort, style, and modern amenities. Whatever your planning, our home provides an ideal setting for a memorable stay. Need a rental car? We have a 2019 Blue Jeep Wrangler Unlimited Sport available via Turo right outside ready for use. Link to book available inside.

Popular amenities for La Mesa villa rentals

Quick stats about villa rentals in La Mesa

  • Total vacation rentals

    Explore 10 vacation rentals in La Mesa

  • Nightly prices starting at

    La Mesa vacation rentals start at ﺩ.ﺇ220 per night before taxes and fees

  • Verified guest reviews

    Over 410 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of La Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across La Mesa rentals

  • 4.7 Average rating

    La Mesa stays receive an average rating of 4.7 out of 5 from guests

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