
Villa vacation rentals in La Mesa
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Top-rated villa rentals in La Mesa
Guests agree: these villas are highly rated for location, cleanliness, and more.

Vintage Home on the Canyon’s Edge
We’re excited to offer our beautiful home in University Heights- just 5 mins from downtown SD. Perched on the edge of a peaceful canyon, the house is surrounded by nature, offering a serene escape while keeping you close to the city’s best attractions. Home features: • 2 comfortable bedrooms • A dedicated study that can double as a third bedroom • 2 full bathrooms • Fully equipped kitchen • Smart TV, WiFi, washer & dryer • A private balcony overlooking the canyon and our inviting hot tub

*Huge HelixCastle-PanoramicView/20+guests welcome
Welcome to our exquisite 5-bedroom (3 stories) home in the desirable neighborhood of Mount Helix in San Diego! This stunning residence is the perfect blend of modern elegance and exceptional comfort, making it an ideal choice for your stay in America's Finest City. Whether you're visiting San Diego for a family vacation, a romantic getaway, or a business trip, our Mount Helix castle, provides the perfect setting for an unforgettable stay. Book your stay with us today to create lasting memories!

☆🏘 Breathtaking 180º Views 🏝Hot Tub🏝 5☆ Reviews
🏝Welcome to the Harbor View Villa! 🏘A 3,500sqft villa with 6 bedrooms, 4 bathrooms and a 800 sqft walk-out deck. Complete with private rooftop hot tub, backyard, outdoor & indoor living. With 180º private day & night views from almost anywhere in the house! Make yourself at home in our Mission-Style Villa with stunning views of the boats in the Harbor, Downtown lights, and Coronado Island! 🗺Ideal for kids Perfect for MCRD & PLNU graduations (5min). Ask about early checkin / late checkout

@Fantastic villa, giant pool, guest house, golf !
This unique fantastic villa with a separate pool house sitting on 1 acre with a spacious living space with large windows. Main house has 4 bedrooms with 2 baths, and a guest house has 1 bedroom with 1 bath. +8 car parking, nice privacy and a fantastic view! Brand new giant size SALT pool with huge size jacuzzi, pool toys, golf zone, a huge grass event field, game field, pool table, foosball, ping pong, Nitendo,2 fire pits and more! Truly one-of-a-kind property don’t miss out! ToT:COSD-00749

6-bed Paradise Villa Pool, hot-tub massage chair
*EV charging available Welcome to Casa Cerro-my incredible chic high-tech modern villa in San Diego! This stylish place to stay is perfect for families and group trips. Its open and airy layout can accommodate up to 14 people. This completely remodeled home is furnished with all the luxuries of home and more that is powered by an iPad for you to use. I love technology. But don't worry you don't have to use it to power up the house, everything has traditional switches/remotes if you choose.

Hidden Villa with Beautiful Furnished Garden Patio
Close to everything, quiet and private. This beautiful 2 Bd Villa seems to be loved by all who stay here. The outdoor private patio feels like your in the forest. Gorgeous custom bath with large marble shower. Full size laundry. Great entertainment system, Roku, Amazon Prime. The home has open beam ceilings, lots of light and a fabulous patio fully furnished for guests, outdoor dining and barbecuing. The home is private, fenced, furry friends are welcome. 2 gig internet w/high speed router

Sunset Lounge | Pool •HotTub •Outdoor TV•GameRoom
☀️Welcome to your luxurious San Diego getaway! ☀️ This spacious 5-bedroom, 2-bathroom 2-level home is perfect for groups and families. Dive into the sparkling blue pool, unwind in the 6-person hot tub, or relax in the cozy outdoor seating areas. Enjoy stunning views from the balcony overlooking the pool, perfect for sunsets. With a central location, plenty of space to relax, and a mix of comfort and elegance, this home is ideal for exploring or unwinding on your San Diego adventure!

Enchanted Paradise! ♨ Pool+Spa+Outdoor Kitchen ☀
Brand New Property! Massive garden of Eden style resort home with sprawling outdoor entertainment area and spacious open concept inside, perfect for large families with kids and responsible adults. Updated top to bottom with all new outdoor and indoor furniture, modern upgrades in all bedrooms and common areas. Centrally located and 20 minutes from the beach and all of SD's top attractions! 8 person hot tub, sparkling gas heated saltwater pool and new outdoor kitchen. Don't miss out!

Casa Charles, Tropical backyard, Pool & Pizza oven
This beautiful family home is a entertainment paradise with a large gourmet kitchen with plenty of pots and pans, dished and kitchen ware, even the spices to cook up a delicious family dinner. but you'll be sure to enjoy the tropical backyard with a bocce court, that includes a pool, a hot tub, an outdoor wood fireplace, a gas fire pit and even a wood fire pizza oven - You're freeway close to everything San Diego has to offer when you stay at this centrally-located retreat.

Gorgeous Beach Villa | Ocean Views + Sleeps 12!
Experience the ultimate family retreat in our spacious 6-bedroom, 4-bath home with breathtaking views of Mission Bay and the Pacific Ocean. Perfect for groups, it features two kitchens, multiple balconies, and a large backyard with a fire pit and grill. Walk to Ocean Beach and Sunset Cliffs or explore nearby attractions like SeaWorld and Balboa Park. Unwind with sea breezes, sunsets, and the sparkle of SeaWorld fireworks. Your unforgettable San Diego getaway starts here!

The Crown Jewel Villa with AC!Bikes,Kayak and SUP!
Escape to the peaceful and coveted beach community of Crown Point in San Diego! This highly sought after neighborhood boasts mostly permanent residents, creating a serene and tranquil environment for our guests. Right across the street from the home, you can find Ski Beach and Park, a favorite spot for families and kids. Explore the variety of local eateries and coffee shops, or take a short walk to popular Sail Bay and the ocean.

Beautiful house in mira mesa
Get ready to enjoy a bright and spacious home right in the heart of Mira Mesa! Just 20 minutes from downtown, the airport, top attractions, and plenty of shopping, it’s the perfect spot for large families or groups of friends eager to experience the best of San Diego. Here, you’ll feel right at home while soaking up all that sunny San Diego has to offer For your safety,security camera in the front door
Popular amenities for La Mesa villa rentals
Private villa rentals

Amazing WaterView Penthouse w/AC

The Bonita Bungalow

Lux Villa: Heated Pool, Sauna, & Gym

Casa Charles, Tropical backyard, Pool & Pizza oven

The Crown Jewel Villa with AC!Bikes,Kayak and SUP!

☆🏘 Breathtaking 180º Views 🏝Hot Tub🏝 5☆ Reviews

Enchanted Paradise! ♨ Pool+Spa+Outdoor Kitchen ☀

Vintage Home on the Canyon’s Edge
Luxury villa rentals

Spacious 4BD | La Jolla • Ocean Views • Jacuzzi

Sanctuary 4BR Church & Deck Near Downtown (18 ppl)

NEW! Mediterranean-Style Villa in Point Loma

3680 Bayside Walk, A Bayside Marina

Cheerful 4-bedroom villa with free parking.
Villa rentals with a pool

10AcreVilla,Heated*SaltPool,MtnView,Mini-Golf,BBQ

1 PRIVATE OCEAN VIEW ROOM IN LUXURY COASTAL HOUSE

Fun Get Away, Vaulted Ceiling, Pool, Hot Tub, New.

10 ACRE Rolling Hills Villa

Villa L'Auberge - 5 star hotel

TWO OCEAN VIEW ROOMS-Quiet Luxury Coastal Retreat

Private oasis

Apartment in hilltop villa: Torrey Pines Suite
Quick stats about villa rentals in La Mesa

Total vacation rentals
Explore 10 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at ﺩ.ﺇ220 per night before taxes and fees

Verified guest reviews
Over 450 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
10 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.7 Average rating
La Mesa stays receive an average rating of 4.7 out of 5 from guests
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- Rentals with an EV charger La Mesa
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- Rosarito Beach
- LEGOLAND California
- SeaWorld San Diego
- Oceanside City Beach
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- University of California-San Diego
- San Diego Zoo Safari Park
- Petco Park
- Ocean Front Walk
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