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Apartment vacation rentals in La Mesa

Find and book unique apartments on Airbnb

Quick stats about apartment rentals in La Mesa

  • Total vacation rentals

    Explore 30 vacation rentals in La Mesa

  • Nightly prices starting at

    La Mesa vacation rentals start at ﺩ.ﺇ 110 per night before taxes and fees

  • Verified guest reviews

    Over 1,420 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    30 of La Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across La Mesa rentals

  • 4.8 Average rating

    La Mesa stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated apartment rentals in La Mesa

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
A serene bedroom is highlighted by tropical leaf-patterned wallpaper. A comfortable bed is layered with neutral-colored pillows and fresh linens. Natural light filters through sheer curtains, illuminating two accent chairs and a small side table, creating a peaceful and inviting atmosphere.
Apartment in Greater North Park
4.99 out of 5 average rating, 126 reviews

Designer Rental w/ FirePit- Petco Park, DT, + Zoo

Welcome to Our 1920s Designer Craftsman Apartment in San Diego’s Best Neighborhood! *Unbeatable Location! Minutes Petco Park, Downtown, Zoo, + Conv Center :) *Washer&Dryer *High end Bedding *Easy Parking *Boutique hotel-like experience Fire pit, grills, and a cocktail/reading den! This stylish apartment is on the edge of the iconic Balboa Park, a short walk from the lively North Park scene, & 5-minute drive to the Gaslamp Quarter and airport. Beaches and Convention Center are only minutes away.

Guest favorite
Apartment in Kensington
4.92 out of 5 average rating, 285 reviews

Studio with Garage, 10 Min to Zoo & Downtown

Now with a private garage! Bright and quiet Kensington studio — a peaceful retreat for couples or solo travelers just minutes from all San Diego has to offer. This thoughtfully designed studio offers comfort and calm with a touch of local charm. Enjoy a plush bed, clean white bed linens and well-equipped kitchen — all within walking distance of Kensington’s beloved cafés and neighborhood restaurants. Quick freeway access makes it easy to explore beaches, Balboa Park, downtown and the Harbor.

Guest favorite
A modern kitchen is showcased with stainless steel appliances, including a refrigerator and oven. Gray cabinetry complements the sleek countertops. Natural light enters through a window above the sink, illuminating both the workspace and open shelving, which holds various kitchen items.
Apartment in Greater North Park
4.94 out of 5 average rating, 401 reviews

Your Cozy North Park Retreat

Cute and charming house located in the heart of North Park. An urban, hip & trendy town. Total sqft is 575. Spacious bathroom & good size bedroom. Sleeps 1-4 comfortably. Enjoy cooking in your fully stocked kitchen and the convenient of in unit laundry. Walking distance to boutique shops, cafes, fun bars, delicious restaurants and yoga studios. Only a short ride to Balboa Park, The Gaslamp District of Downtown, Little Italy, Coronado Island, San Diego Zoo, Sea World, beaches, USD, SDSU and more!

Guest favorite
A cozy living room features a yellow armchair and a sleek coffee table. Natural light filters through sheer curtains, illuminating the space. A flat-screen TV is positioned on a modern media console, beside decorative items including a tall potted plant and a small basket.
Apartment in University Heights
4.93 out of 5 average rating, 136 reviews

Bright Oasis in the Heart of University Heights

Enjoy this peacefully tucked-away neighborhood gem. Exceptional restaurants, top-rated bars, and exciting nightlife are all waiting only blocks away. This space is only a 5-minute walk from University Heights Main Street restaurants and shops and a 10-minute walk to the bus hub for direct Down Town/Gaslamp access or San Diego's train station for easy coastal exploration. Bike lanes make North Park, Normal Heights, South Park, Hillcrest, and Balboa Park quickly accessible by scooter or bike

Guest favorite
A modern living area is depicted, featuring a spacious white sofa adorned with cushions. Large glass doors open to a balcony, allowing natural light to fill the room. A stylish coffee table sits in front of the sofa, while an elegant dining table is visible nearby.
Apartment in Greater North Park
4.83 out of 5 average rating, 299 reviews

NEW Modern North Park. Short Walk From Everything

Welcome to Kansas Modern, a place where luxury and adventure go hand in hand. Designed by local Architect & Developer Beri Varol, this brand new mixed-use community is located in the heart of North Park. This ground floor (walk-up) apartment features a private bedroom and semi-private sleeping loft, each with a queen bed. The apartment is in the heart of some of San Diego's most exciting new and established restaurants. The kitchen is also fully stocked if you'd rather prepare a meal at home

Guest favorite
Apartment in City Heights
4.96 out of 5 average rating, 331 reviews

Hot Tub & Sauna | San Diego Getaway

Looking for a place to thoroughly relax and reset, while soaking into a private hot tub and infrared sauna? Looking for a peaceful home with a dedicated workspace, A/C, HD monitor, and high-speed WiFi? Looking to stay central to San Diego's eclectic neighborhoods while being tucked away on a quiet residential street? Looking for an efficient apartment with brand new appliances? This is the place for you! Petco Park / Downtown ~ 10 min. Pacific Beach/La Jolla ~ 20 min. Old Town ~ 13 min.

Top guest favorite
A bedroom is equipped with a metal bed frame featuring a floral-patterned quilt. Two bedside lamps cast soft light, and wall art in calming colors adds a touch of design. Sliding glass doors reveal outdoor access to a private patio area with furniture.
Apartment in La Mesa
4.98 out of 5 average rating, 186 reviews

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

Guest favorite
A spacious lounge area features a large, L-shaped gray couch, a contemporary glass coffee table, and a flat-screen TV mounted on the wall. A fireplace with a dark mantel adds warmth, and light enters through the black-framed windows that lead to a private outdoor space.
Apartment in La Mesa
4.93 out of 5 average rating, 370 reviews

A Little Bit of Luxury in La Mesa! Private & Gated

Relax and stretch out on your king size bed or take a short stroll to La Mesa Village to take in the new shops, bars & restaurants. Enjoy your large lounge with smart tv & fireplace and while away the evening on your fully lit deck. The delights of downtown San Diego, beaches, zoo & airport are only a 15-20 minute drive away. Within walking distance to La Mesa Blvd Tolley stop. Apartment & parking for 1 vehicle is private & gated with plenty of on-street parking.

Guest favorite
A serene sunset view is captured with soft hues of purple, pink, and orange streaking the sky. Silhouetted hills create a calming backdrop, while the dimming light gently transitions the scenery into evening.
Apartment in Spring Valley
4.89 out of 5 average rating, 177 reviews

Comfy, Cozy Flat With Pool & Spa!

Our flat has a patio that enjoys great sunsets. We are freeway close to all, easy in and easy out!! You’ll love the place because of the comfy bed, space, patio and access to pool and spa. Also, the yard can be enjoyed for relaxing, eating, bonfires, horseshoes and cornhole. An adjoining space is also an AIRBNB studio suite. Great for traveling friends or as an alternative place to consider for your stay. Look for Foemer man Cave with Pool And Spa.

Top guest favorite
The studio features a brown leather sofa and a round coffee table atop a decorative rug. A queen bed is positioned against the wall, flanked by two lamps. Two framed artworks and a surfboard enhance the decor, while a ceiling fan provides ventilation.
Apartment in Coronado
4.9 out of 5 average rating, 147 reviews

Large Beach Studio, 5 Min Walk to Coronado Beach!

Welcome to the B Avenue Bungalows! Come kick back and enjoy the island vibes in this newly renovated condo right in Coronado Village and also just a short 5 to 10-minute walk to Coronado Beach. After your day down at the beach, stopping at the local restaurants, or taking a boat ride around San Diego bay, come back and chill out by the BBQ, or inside enjoying the smart TV or relaxing on the queen bed. Looking forward to your visit!

Top guest favorite
A tranquil outdoor space features a large tree providing shade over a wooden platform. A serene Buddha statue is situated on the platform, surrounded by vibrant foliage and decorative stones. Stairs lead to the upper apartments, while lush greenery creates a calming atmosphere.
Apartment in Hillcrest
4.96 out of 5 average rating, 528 reviews

Hillcrest #1 Cozy Private Balcony ZenGarden Garage

Heat up the cherry red kettle or a complementary coffee, sit back and enjoy, on your private balcony, overlooking the serene, Zen garden, while listening to the zen fountain. Zen Buddha, awaits your exit and every arrival to the property, whether retuning from the eclectic Hillcrest nightlife, or a scenic stroll through Balboa Park, with its many museums, gardens, fountains, restaurants and coffee shops.

Superhost
A spacious living area features large windows that fill the room with natural light. A plush white sofa and bright red chairs provide seating, while a round coffee table sits centrally on a red carpet. A wall-mounted TV is visible for entertainment.
Apartment in Downtown San Diego
4.88 out of 5 average rating, 1,838 reviews

At Mine | Spacious Suite in the Gaslamp Quarter

This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.

Popular amenities for La Mesa apartment rentals

When is the best time to visit La Mesa?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceﺩ.ﺇ 408ﺩ.ﺇ 393ﺩ.ﺇ 408ﺩ.ﺇ 397ﺩ.ﺇ 404ﺩ.ﺇ 404ﺩ.ﺇ 422ﺩ.ﺇ 404ﺩ.ﺇ 400ﺩ.ﺇ 400ﺩ.ﺇ 422ﺩ.ﺇ 411
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