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Apartment vacation rentals in La Mesa

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Top-rated apartment rentals in La Mesa

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A modern living area is depicted, featuring a spacious white sofa adorned with cushions. Large glass doors open to a balcony, allowing natural light to fill the room. A stylish coffee table sits in front of the sofa, while an elegant dining table is visible nearby.

Apartment in Greater North Park

4.83 out of 5 average rating, 259 reviews

NEW Modern North Park. Short Walk From Everything

Welcome to Kansas Modern, a place where luxury and adventure go hand in hand. Designed by local Architect & Developer Beri Varol, this brand new mixed-use community is located in the heart of North Park. This ground floor (walk-up) apartment features a private bedroom and semi-private sleeping loft, each with a queen bed. The apartment is in the heart of some of San Diego's most exciting new and established restaurants. The kitchen is also fully stocked if you'd rather prepare a meal at home

A modern living area is showcased, featuring a comfortable sofa adorned with decorative pillows. A large television is positioned on a sleek black media unit. Distinctive concrete walls add to the industrial style, complemented by a vibrant piece of wall art and a surfboard leaning against a shelf.

Apartment in Mission Hills

4.89 out of 5 average rating, 170 reviews

★Lux Designer Penthouse | Balcony w/ Stunning View

Step into the comfort of this luxurious 2BR 2Bath penthouse designed by an award-winning architect in Mission Hills, a sought-after San Diego neighborhood. It promises an urban retreat with stunning, #instaworthy views, close to restaurants, bars, shops, and numerous attractions. Contemporary industrial design and a rich amenity list will satisfy all your needs. ✔ 2 BRs w/ Queen Beds ✔ Open Design Living ✔ Fully Equipped Kitchen ✔ Balcony w/ Seating ✔ Smart TV ✔ Free Parking See more below!

Top guest favorite

A spacious studio features a large bed with decorative throws, complemented by a cozy chair and a small dining table. Tall windows allow natural light to illuminate the room, while neutral-colored curtains add warmth. A wardrobe provides additional storage alongside tasteful artwork.

Apartment in Serra Mesa

4.97 out of 5 average rating, 369 reviews

Anna’s modern & private San Diego guest studio!

Welcome to Anna's Getaway! Recently updated, beautifully detailed, clean, modern & spacious studio, private entrance, patio, A/C & heating, Tesla Solar System & plenty street parking! High ceilings! Family friendly: Infant travel crib, high chair, toys & baby items. WiFi, Netflix and cable TV. Fully equipped kitchenette. Shower & bathtub. Washer & dryer. Centrally located in a quiet, safe & peaceful neighborhood, walking distance to playgrounds & parks! Whole house water filtration system!

A spacious living area features large windows that fill the room with natural light. A plush white sofa and bright red chairs provide seating, while a round coffee table sits centrally on a red carpet. A wall-mounted TV is visible for entertainment.

Apartment in San Diego

4.9 out of 5 average rating, 1,459 reviews

At Mine | Spacious Suite in the Gaslamp Quarter

This unit is a meticulously renovated historical hotel suite, designed by the renowned Italian firm Pininfarina, located in Downtown San Diego. Nestled in the vibrant Gaslamp Quarter, you'll find yourself in the midst of nightlife with an array of restaurants and bars in close proximity. The suite provides private and spacious accommodations catering to both vacationers and business travelers. Its features include a comfortable king-sized bed, a smart TV, central AC, and a mini-fridge

Top guest favorite

A bedroom is equipped with a metal bed frame featuring a floral-patterned quilt. Two bedside lamps cast soft light, and wall art in calming colors adds a touch of design. Sliding glass doors reveal outdoor access to a private patio area with furniture.

Apartment in La Mesa

4.98 out of 5 average rating, 154 reviews

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

A lush garden path leads through vibrant greenery, featuring blooming roses and various colorful flowers. Tropical palm trees rise in the background, and the exterior of the house is painted in a soft hue, creating a welcoming atmosphere in the outdoor space.

Apartment in Cherokee Point

4.88 out of 5 average rating, 228 reviews

Private Studio close by North Park

Fiber WIFI, twin bed, TV (Roku & Netflix), microwave, fridge, hotplate, toaster, coffee maker, desk, office chair, armchair, folding table, iron & board. No pets please. Quiet, clean, central location. Free offstreet parking. Walk to University Ave eateries, shops, buses. See Host Guidebook. 1 mi to 30th St/North Park, 10 min drive to Balboa Park, Downtown, Airport. #7, 10 & 215 bus to downtown. Near I-I5, 805, I-8 freeways. Check-in: Lockbox. Cleaned & Disinfected for Your Safety.

Top guest favorite

A modern studio apartment features an open layout with stylish wood flooring. A comfortable brown seating area is positioned beside a decorative black and white rug. A dining table with dishes is set up nearby, while kitchen appliances are arranged along the wall.

Apartment in Hillcrest

4.98 out of 5 average rating, 105 reviews

Stylish Studio w/Parking, Near Balboa Park & Zoo

This rare found is the best place to stay for you. Spacious, very quiet and supplied with everything you will need to feel like at home. Located in one step from all best restaurants, less than a mile from Balboa Park and Zoo, a few min from Downtown, Airport, Coronado, Mission Bay and all signs you want to see! The apartment has washer, dryer and free parking. You will have an access to an amazing rooftop with jacuzzi and all amenties! The location is very safe and super walkable.

An outdoor patio is shown, surrounded by wooden fencing for privacy. A hot tub is positioned to one side, with temperature controls visible. A round dining table with four red chairs occupies the grassy area, illuminated by bright sunlight.

Apartment in City Heights

4.98 out of 5 average rating, 230 reviews

~Hot Tub Getaway in Central San Diego~

Looking for a place to thoroughly relax and reset, while soaking into a private hot tub? Looking for a peaceful home with a dedicated workspace, A/C, HD monitor, and high-speed WiFi? Looking to stay central to San Diego's eclectic neighborhoods while being tucked away on a quiet residential street? Looking for an efficient apartment with brand new appliances? This is the place for you! Petco Park / Downtown ~ 10 min. Pacific Beach/La Jolla ~ 20 min. Old Town ~ 13 min.

A spacious lounge area features a large, L-shaped gray couch, a contemporary glass coffee table, and a flat-screen TV mounted on the wall. A fireplace with a dark mantel adds warmth, and light enters through the black-framed windows that lead to a private outdoor space.

Apartment in La Mesa

4.94 out of 5 average rating, 334 reviews

A Little Bit of Luxury in La Mesa! Private & Gated

Relax and stretch out on you king size bed or take a short stroll to La Mesa Village to take in the new shops, bars & restaurants. Enjoy your large lounge with flat screen TV & fireplace and while away the evening on your fully lit deck. The delights of downtown San Diego, beaches, zoo & airport are only a 15-20 minute drive away. Within walking distance to La Mesa Blvd Tolley stop. Apartment & parking for 1 vehicle is private & gated with plenty of on-street parking.

A tranquil outdoor space features a large tree providing shade over a wooden platform. A serene Buddha statue is situated on the platform, surrounded by vibrant foliage and decorative stones. Stairs lead to the upper apartments, while lush greenery creates a calming atmosphere.

Apartment in Hillcrest

4.96 out of 5 average rating, 485 reviews

Hillcrest #1 Cozy Private Balcony ZenGarden Garage

Heat up the cherry red kettle or complementary coffee and indulge in a morning snack from your private balcony, overlooking the serene Zen garden, and listening to the zen fountain, creating a chilled ambience. Zen Buddha, awaits your exit and every arrival to the property, whether retuning from the eclectic Hillcrest nightlife, or a scenic stroll through Balboa Park, with its many museums, gardens, fountains, restaurant and coffee shops.

A cozy sleeping area features a spacious bed adorned with white linens and vibrant red accents. Two nightstands with lamps flank the bed, while a colorful painting of a boat hangs above. Sheer curtains allow natural light to filter in from the window.

Apartment in Kensington

4.91 out of 5 average rating, 237 reviews

Luxury queen bed, full kitchen, very walkable

Bright, quiet and cozy studio with a fully stocked kitchen and spacious bathroom. Unlike many studios, the kitchen is separate from the sleeping area. Enjoy natural light by day or blackout curtains for restful nights. The adjustable mattress lets you relax, work, or watch TV in total comfort. Just minutes from the freeway, yet peaceful and private—perfect for a relaxing stay or productive trip.

A dining area features a large, light-colored table surrounded by six green chairs. A potted plant adds a touch of greenery, while a pendant light hangs above. Natural light enters through a large window adorned with soft curtains, enhancing the space’s openness.

Apartment in San Diego

4.94 out of 5 average rating, 127 reviews

Newly Remodeled Modern Apartment

This 2 bedroom, 1 bathroom apartment is located in Valencia Park San Diego, offering a variety of popular attractions. Your family will be close to everything when you stay at this centrally-located place. 4.9 Miles to Downtown San Diego 7.5 Miles to the San Diego International Airport 5.2 Miles to the San Diego Zoo 4.9 Miles to Petco Park 10 Miles to Seaworld

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Popular amenities for La Mesa apartment rentals

Free parking on premises

Air conditioning

Weekly apartment rentals

Top guest favorite

A cozy studio space features a spacious bed adorned with a sunflower-patterned blanket and decorative pillows. Sunflower artwork and accents are displayed on the walls and dresser, enhancing the cheerful atmosphere. A standing mirror is positioned on the dresser, complementing the room's bright decor.

Apartment in El Cajon

5 out of 5 average rating, 14 reviews

Sunflower Heaven Studio - Long Term Welcome!

A resort-style pool is surrounded by lounge chairs and umbrellas, set against a backdrop of palm trees and sunny blue skies. The inviting water glistens, offering a serene atmosphere for relaxation.

Apartment in Kearny Mesa

4.95 out of 5 average rating, 20 reviews

Endless Summer: Luxe 1BR w/ Resort-Style Amenities

Apartment in Greater North Park

5 out of 5 average rating, 63 reviews

NEW Organic Modern Luxury Oasis

A cozy living area features a gray sofa adorned with two light-colored pillows, positioned across from a simple white bookshelf. A doorway leads to a well-equipped kitchen, with dining arrangements visible in the background, offering a functional and welcoming environment.

Apartment in Spring Valley

4.9 out of 5 average rating, 81 reviews

Guest Suite in Spring Valley, dedicated parking.

A bright and modern sleeping area features a spacious bed with a white quilt and decorative pillows. Two bedside tables with lamps are positioned on either side. A mirrored wardrobe and artwork depicting soft water tones enhance the room’s inviting feel.

Apartment in La Mesa

5 out of 5 average rating, 15 reviews

San Diego Suite: Local charm ideal for work trips!

A modern living space features a light-colored sofa paired with a black dining table and chairs. A fully equipped kitchen is visible in the background, showcasing wooden cabinetry and stainless steel appliances. Natural light filters through the sliding glass doors.

Apartment in Tijuana

5 out of 5 average rating, 27 reviews

Centrally located and safe, apartment in Otay Alameda

A modern living space is shown, featuring a comfortable gray sofa adorned with colorful throw pillows. A dining table with four black chairs is positioned nearby, with a large window providing natural light and scenic views. A decorative plant adds a touch of greenery to the room.

Apartment in Zona Centro

4.97 out of 5 average rating, 61 reviews

A 2 bedroom apartment

Top guest favorite

A cozy living area features a light-colored sofa adorned with a decorative pillow. A coffee table is positioned in front, surrounded by plants. A partition with intricate design separates the space from the sleeping area, which is visible in the background, showcasing a bed and air conditioning unit.

Apartment in Spring Valley

4.98 out of 5 average rating, 63 reviews

Private Studio on a Hill with City and Pool View

Private apartment rentals

Top guest favorite

A well-equipped kitchen is displayed, showcasing modern appliances including a stove, microwave, and coffee maker. Open shelving holds neatly arranged dishes and decorative items. A cozy seating area is provided, featuring soft cushions, optimizing both functionality and comfort.

Apartment in Greater North Park

4.99 out of 5 average rating, 78 reviews

Charming Private Loft: Walkable to South Park

Top guest favorite

A serene bedroom is highlighted by tropical leaf-patterned wallpaper. A comfortable bed is layered with neutral-colored pillows and fresh linens. Natural light filters through sheer curtains, illuminating two accent chairs and a small side table, creating a peaceful and inviting atmosphere.

Apartment in Greater North Park

5 out of 5 average rating, 41 reviews

Designer Craftsman: Heart of San Diego w/ FirePit

A comfortable studio layout is featured, including a wall-mounted TV, a dining table with four wooden chairs, and a leather sofa. A spacious bed is located in the corner, draped in blue bedding. Natural light brightens the room through a nearby window.

Apartment in Pacific Beach

4.92 out of 5 average rating, 345 reviews

Surf Studio!

A modern kitchen is displayed with sleek dark cabinetry and a large island featuring a glossy black countertop. Stainless steel appliances are fitted into the cabinetry. Large windows provide natural light and views of the city beyond.

Apartment in Downtown

4.91 out of 5 average rating, 32 reviews

Panoramic Views, Zen Penthouse!

The sleeping area features a full-sized bed with a textured blue bedding set. A decorative pillow with a friendly message rests on the bed. A piece of artwork depicting a black dog is displayed on the wall above, adding a subtle touch to the space.

Apartment in Old Town

5 out of 5 average rating, 16 reviews

Cozy lovely studio

Top guest favorite

A light-filled living area is showcased, featuring a modern white sofa and two accent chairs. A large television hangs on the wall opposite a sleek, white entertainment unit. A dining table is visible in the background, complemented by a view of the kitchen.

Apartment in Fox Canyon

5 out of 5 average rating, 44 reviews

Le Bleu At Fox Canyon

Top guest favorite

A modern multi-story building is shown, featuring a blend of glass and concrete elements. A landscaped area with greenery is visible in the foreground, while the driveway leads to a secure entrance. The exterior showcases a contemporary design with a neutral color palette.

Apartment in Tijuana

5 out of 5 average rating, 16 reviews

Luxury apartment in Tijuana!

Top guest favorite

The studio features a spacious layout with a comfortable sofa facing a mounted flat screen television. Natural light fills the room through multiple windows. A king-sized bed is positioned in the background, and a wooden coffee table adds a cozy touch to the living area.

Apartment in South Park

4.97 out of 5 average rating, 58 reviews

Boutique Historic Studio Balboa Park W/D

Apartment rentals with a hot tub

The image presents a serene pool area surrounded by palm trees and lounge chairs. The sparkling water reflects a clear blue sky. A shaded seating area with a pergola is visible, providing a comfortable spot to relax beside the pool.

Apartment in Mission Valley East

4.83 out of 5 average rating, 111 reviews

"10 min away from everything"

A colorful wooden sign welcomes visitors to Cardiff by the Sea, featuring a surfing figure against a blue sky. Coastal vegetation and a glimpse of the ocean can be seen in the background, highlighting the area’s beach community charm.

Apartment in Cardiff

4.94 out of 5 average rating, 121 reviews

Cute, clean private studio. Close to the beach!

A modern living area features a cozy sofa with green accent pillows, situated beside a light wood coffee table. A large wall mirror reflects the open space, while a fully equipped kitchen is visible in the background. Warm wood flooring enhances the inviting atmosphere.

Apartment in Downtown

5 out of 5 average rating, 8 reviews

NEW Downtown Luxe King Suite with Sauna & Pool Acc

A modern living area is seen featuring a comfortable sofa facing large floor-to-ceiling windows showcasing city views. A small coffee table is placed on a textured rug, with decorative items displayed. Two tall stools and shelves add to the stylish decor.

Apartment in Gavilondo

4.88 out of 5 average rating, 17 reviews

Exclusive luxe Penthouse | restaurants+pool+views

A bright living area features a light blue sofa adorned with decorative pillows. A wooden coffee table is positioned in front, complemented by a potted plant. A ceiling fan hangs above, while sunlight filters through sheer curtains, illuminating the space.

Apartment in San Diego

4.9 out of 5 average rating, 160 reviews

Hidden Gem with Hot Tub and Parking - 4 Guests

A contemporary sitting area features a brown leather sofa alongside an armchair. A stylish coffee table holds an open magazine. A large window offers views of the cityscape, while a leafy plant adds a touch of greenery to the space.

Apartment in Gavilondo

4.77 out of 5 average rating, 103 reviews

Adamant GRAND Toreo contemporary

A bright living area features a spacious sofa and a wooden coffee table on a colorful rug. A ceiling fan hangs above, providing comfort and airflow. Artwork adorns the walls, and a desk with a chair offers a functional workspace. Natural light filters through the windows.

Apartment in South Park

4.84 out of 5 average rating, 316 reviews

Walk to Balboa Park South Park Hot Tub Hideaway

The entry area of the unit features a blue door that opens to the outside, allowing natural light to fill the space. A patterned chair is positioned beside a small table, which holds a plant. Informational posters and a textured wall art piece add visual interest.

Apartment in La Jolla

4.89 out of 5 average rating, 174 reviews

La Jolla Windansea Paradise Three

Quick stats about apartment rentals in La Mesa

Total rentals
40 properties
Nightly prices starting at
ﺩ.ﺇ110 before taxes and fees
Total number of reviews
1.1K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
10 properties have a pool

Destinations to explore