
Apartment vacation rentals in La Mesa
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Top-rated apartment rentals in La Mesa
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Bright Oasis in the Heart of University Heights
Enjoy this peacefully tucked-away neighborhood gem. Exceptional restaurants, top-rated bars, and exciting nightlife are all waiting only blocks away. This space is only a 5-minute walk from University Heights Main Street restaurants and shops and a 10-minute walk to the bus hub for direct Down Town/Gaslamp access or San Diego's train station for easy coastal exploration. Bike lanes make North Park, Normal Heights, South Park, Hillcrest, and Balboa Park quickly accessible by scooter or bike.

NEW in North Park! A Short walk or drive to all SD
Welcome to Kansas Modern, a place where luxury and adventure go hand in hand. Designed by local Architect & Developer Beri Varol, this brand new mixed-use community is located in the heart of North Park. This ground floor (walk-up) apartment features a private bedroom and semi-private sleeping loft, each with a queen bed. The apartment is in the heart of some of San Diego's most exciting new and established restaurants. The kitchen is also fully stocked if you'd rather prepare a meal at home

Hot Tub & Sauna | San Diego Getaway
Looking for a place to thoroughly relax and reset, while soaking into a private hot tub and infrared sauna? Looking for a peaceful home with a dedicated workspace, A/C, HD monitor, and high-speed WiFi? Looking to stay central to San Diego's eclectic neighborhoods while being tucked away on a quiet residential street? Looking for an efficient apartment with brand new appliances? This is the place for you! Petco Park / Downtown ~ 10 min. Pacific Beach/La Jolla ~ 20 min. Old Town ~ 13 min.

Central location, full kitchen, extra comfy bed
Bright and quiet Kensington studio — a peaceful retreat for couples or solo travelers just minutes from all San Diego has to offer. Nestled on a quiet, tree-lined street, this thoughtfully designed studio offers comfort and calm with a touch of local charm. Enjoy a plush bed, clean white bed linens and well-equipped kitchen — all within walking distance of Kensington’s beloved cafés and neighborhood restaurants. Quick freeway access makes it easy to explore beaches, Balboa Park, downtown.

At Mine | Spacious Suite in the Gaslamp Quarter
This unit is a meticulously renovated historical hotel suite, designed by the renowned Italian firm Pininfarina, located in Downtown San Diego. Nestled in the vibrant Gaslamp Quarter, you'll find yourself in the midst of nightlife with an array of restaurants and bars in close proximity. The suite provides private and spacious accommodations catering to both vacationers and business travelers. Its features include a comfortable king-sized bed, a smart TV, central AC, and a mini-fridge

Lovely Hideaway Studio by Village-Private Patio
Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

Designer Rental w/ FirePit- Petco Park, DT, + Zoo
Welcome to Our 1920s Designer Craftsman Apartment in San Diego’s Best Neighborhood! *Unbeatable Location! *Washer & Dryer *High end Bedding! *Easy Parking *Boutique hotel-like experience Fire pit, grills, and a cocktail/reading den! This stylish apartment is on the edge of the iconic Balboa Park, a short walk from the lively North Park scene, & 5-minute drive to the Gaslamp Quarter and the airport. San Diego’s beaches and Convention Center are only minutes away.

A Little Bit of Luxury in La Mesa! Private & Gated
Relax and stretch out on your king size bed or take a short stroll to La Mesa Village to take in the new shops, bars & restaurants. Enjoy your large lounge with smart tv & fireplace and while away the evening on your fully lit deck. The delights of downtown San Diego, beaches, zoo & airport are only a 15-20 minute drive away. Within walking distance to La Mesa Blvd Tolley stop. Apartment & parking for 1 vehicle is private & gated with plenty of on-street parking.

Comfy, Cozy Flat With Pool & Spa!
Our flat has a patio that enjoys great sunsets. We are freeway close to all, easy in and easy out!! You’ll love the place because of the comfy bed, space, patio and access to pool and spa. Also, the yard can be enjoyed for relaxing, eating, bonfires, horseshoes and cornhole. An adjoining space is also an AIRBNB studio suite. Great for traveling friends or as an alternative place to consider for your stay. Look for Foemer man Cave with Pool And Spa.

Hillcrest #1 Cozy Private Balcony ZenGarden Garage
Heat up the cherry red kettle or complementary coffee and indulge in a morning snack from your private balcony, overlooking the serene Zen garden, and listening to the zen fountain, creating a chilled ambience. Zen Buddha, awaits your exit and every arrival to the property, whether retuning from the eclectic Hillcrest nightlife, or a scenic stroll through Balboa Park, with its many museums, gardens, fountains, restaurant and coffee shops.

Newly Remodeled Modern Apartment
This 2 bedroom, 1 bathroom apartment is located in Valencia Park San Diego, offering a variety of popular attractions. Your family will be close to everything when you stay at this centrally-located place. 4.9 Miles to Downtown San Diego 7.5 Miles to the San Diego International Airport 5.2 Miles to the San Diego Zoo 4.9 Miles to Petco Park 10 Miles to Seaworld

Bright & Airy Craftsman, Free Parking, WasherDryer
This unit is in the heart of University Heights - a charming and walkable San Diego neighborhood filled with restaurants, coffee shops, and boutiques. It is a mere 5 - 15 minute drive to the city’s finest attractions including the San Diego Zoo, Balboa Park, SeaWorld, the Gaslamp (downtown), the convention center, Mission Beach, Hillcrest, Coronado, and more.
Popular amenities for La Mesa apartment rentals
Weekly apartment rentals

North Park Penthouse~King Beds~Workspaces~Parking!

Clean comfy spacious centrally located San Diego

Breathtaking Ocean, Bay, City & Petco Park Views

Charming 2BD, 1BA in La Mesa

La Casita South Park

Beachy Cottage

Private Studio on a Hill with City and Pool View

Basement Apartment
Private apartment rentals

Honeycomb Hideout

NEW! 6 Guest,Balcony, Full Kitchen, Wsher and Dryr

Stunning Views & 1 min to Petco Park 1BD Apartment

Immaculate Home near Balboa Park, SD Zoo, & Cafés

Modern Pad w/ Game Room Arcade!

Quaint Apt with International decor

Chic 1Bd/1Bath Oasis| Steps away from Little Italy

Le Bleu At Fox Canyon
Apartment rentals with a hot tub

Fun and relaxation in the same location.

2 Bed Hidden Gem | Hot Tub, Parking | Midtown SD

Resort style unique & tranquil vacation escape

Downtown Escape I Free Garage Parking

Steps to Balboa Park South Park Spa 1 Bedroom

La Jolla Windansea Paradise Three

Bike to North Park, Loaner bikes/surfboards, Games

Cozy Studio Steps from the Beach
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ393 | ﺩ.ﺇ386 | ﺩ.ﺇ393 | ﺩ.ﺇ397 | ﺩ.ﺇ404 | ﺩ.ﺇ404 | ﺩ.ﺇ422 | ﺩ.ﺇ404 | ﺩ.ﺇ400 | ﺩ.ﺇ400 | ﺩ.ﺇ422 | ﺩ.ﺇ411 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about apartment rentals in La Mesa

Total vacation rentals
Explore 30 vacation rentals in La Mesa

Nightly prices starting at
La Mesa vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees

Verified guest reviews
Over 1,490 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
30 of La Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across La Mesa rentals

4.8 Average rating
La Mesa stays are highly rated by guests—averaging 4.8 out of 5!
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- Rentals with a hot tub La Mesa
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- Rosarito Beach
- LEGOLAND California
- Oceanside City Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- University of California-San Diego
- San Diego Zoo Safari Park
- Petco Park
- Ocean Front Walk
- Torrey Pines State Beach
- Tijuana Beach
- Coronado Beach
- Pacific Beach
- Balboa Park
- San Diego Zoo
- Pechanga Resort Casino
- Liberty Station
- Moonlight State Beach
- La Misión Beach
- Anza-Borrego Desert State Park
- Belmont Park
- Sesame Place San Diego
- Oceanside Harbor
- Coronado Shores Beach




