Apartment vacation rentals in La Mesa

Find and book unique apartments on Airbnb

Quick stats about apartment rentals in La Mesa

  • Total vacation rentals

    Explore 30 vacation rentals in La Mesa

  • Nightly prices starting at

    La Mesa vacation rentals start at ﺩ.ﺇ 110 per night before taxes and fees

  • Verified guest reviews

    Over 1,510 verified reviews to help you choose

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    30 of La Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across La Mesa rentals

  • 4.8 Average rating

    La Mesa stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated apartment rentals in La Mesa

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
A serene bedroom is highlighted by tropical leaf-patterned wallpaper. A comfortable bed is layered with neutral-colored pillows and fresh linens. Natural light filters through sheer curtains, illuminating two accent chairs and a small side table, creating a peaceful and inviting atmosphere.
Apartment in Greater North Park
4.99 out of 5 average rating, 134 reviews

Designer Rental w/ FirePit- Petco Park, DT, + Zoo

Welcome to Our 1920s Designer Craftsman Apartment in San Diego’s Best Neighborhood! *Unbeatable Location! Minutes Petco Park, Downtown, Zoo, + Conv Center :) *Washer&Dryer *High end Bedding *Easy Parking *Boutique hotel-like experience Fire pit, grills, and a cocktail/reading den! This stylish apartment is on the edge of the iconic Balboa Park, a short walk from the lively North Park scene, & 5-minute drive to the Gaslamp Quarter and airport. Beaches and Convention Center are only minutes away.

Guest favorite
Apartment in City Heights
5.0 out of 5 average rating, 102 reviews

Midcity Retreat

Chic studio in central San Diego! Enjoy a full kitchen, in-unit washer/dryer, WiFi, and wall-mounted AC with heating and backup heater. Located on Thorn St with easy access to I-8, I-15, I-805 & I-94, minutes to downtown and Balboa Park. Perfect for solo travelers or couples (max 2 guests). A small neighborhood market is a 1-minute walk away. Please note: this is a simple, comfortable stay in a working San Diego neighborhood—not a luxury or beachfront property. No baby items (cribs/high chairs).

Superhost
A modern living area is depicted, featuring a spacious white sofa adorned with cushions. Large glass doors open to a balcony, allowing natural light to fill the room. A stylish coffee table sits in front of the sofa, while an elegant dining table is visible nearby.
Apartment in Greater North Park
4.82 out of 5 average rating, 308 reviews

North Park Modern Architecture. Close to all of SD

Welcome to Kansas Modern, a place where luxury and adventure go hand in hand. Designed by local Architect & Developer Beri Varol, this brand new mixed-use community is located in the heart of North Park. This ground floor (walk-up) apartment features a private bedroom and semi-private sleeping loft, each with a queen bed. The apartment is in the heart of some of San Diego's most exciting new and established restaurants. The kitchen is also fully stocked if you'd rather prepare a meal at home

Top guest favorite
A cozy living area features a light-colored sofa adorned with a decorative pillow. A coffee table is positioned in front, surrounded by plants. A partition with intricate design separates the space from the sleeping area, which is visible in the background, showcasing a bed and air conditioning unit.
Apartment in Spring Valley
4.99 out of 5 average rating, 102 reviews

Private Studio on a Hill with City and Pool View

Beautiful studio. 10ft ceilings and giant windows for stunning sunsets. Motorized blackout blinds for sleeping and privacy. Curtain divider between living room and sleeping area. Luxurious bathroom! King sized bed in the bedroom, queen-sized pullout couch in the living room. Full kitchen. Washer and dryer in unit. Our daughter and her pets stay here when it’s not rented. Not good for those with cat/dog allergies. Quiet, safe cul-de-sac on a hill, 12 miles from the airport and downtown SD.

Guest favorite
Apartment in Kensington
4.92 out of 5 average rating, 291 reviews

Fully equipped kitchen, garage, close to SDSU, zoo

Now with a private garage! Bright and quiet Kensington studio, a peaceful retreat for couples or solo travelers just minutes from all San Diego has to offer. Enjoy a plush bed and well-equipped kitchen — all within walking distance of Kensington’s cafés and neighborhood restaurants. Quick freeway access to easily explore beaches, Balboa Park, downtown and the Harbor. Please note the garage is suitable for a compact or regular-sized car. Larger vehicles can park in front of the driveway.

Guest favorite
Apartment in City Heights
4.96 out of 5 average rating, 345 reviews

Hot Tub & Sauna | San Diego Getaway

Looking for a place to thoroughly relax and reset, while soaking into a private hot tub and infrared sauna? Looking for a peaceful home with a dedicated workspace, A/C, HD monitor, and high-speed WiFi? Looking to stay central to San Diego's eclectic neighborhoods while being tucked away on a quiet residential street? Looking for an efficient apartment with brand new appliances? This is the place for you! Petco Park / Downtown ~ 10 min. Pacific Beach/La Jolla ~ 20 min. Old Town ~ 13 min.

Top guest favorite
The open-concept living space features a dining area with wooden chairs and a round table, a comfortable couch facing expansive glass doors, and views of Mission Bay. A tray with sliced fruit and drinks rests on the kitchen counter, welcoming relaxation and enjoyment.
Apartment in Bay Park
4.99 out of 5 average rating, 119 reviews

Stunning Bay View Getaway

Spacious one bedroom with large deck overlooking Mission Bay. This second-floor space is all yours, with a private entrance, hot tub, and expansive view of the bay, neighboring beach communities, and even a strip of the ocean. Perfect for a romantic and luxurious getaway, even if one or both of you need to do a little remote work. Only minutes to public transportation, Sea World, beaches, and all that Mission Bay Park offers (boat rentals, biking, jet-skiing, parasailing, kayaking, etc.)

Top guest favorite
A bedroom is equipped with a metal bed frame featuring a floral-patterned quilt. Two bedside lamps cast soft light, and wall art in calming colors adds a touch of design. Sliding glass doors reveal outdoor access to a private patio area with furniture.
Apartment in La Mesa
4.98 out of 5 average rating, 191 reviews

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

Guest favorite
Apartment in Coronado
4.91 out of 5 average rating, 181 reviews

Oceanfront Penthouse with Private Deck & Grill

Enjoy breathtaking 360-degree views from your private rooftop deck, complete with a firepit and built-in grill, all right on the beach! This beautiful condo features two bedrooms, two bathrooms, a rooftop deck, and an additional private balcony at the front. Located within walking distance to restaurants and nightlife, it's perfectly positioned to be close to the action yet still tucked away for a peaceful retreat. Don’t forget to check water quality online before swimming.

Guest favorite
Apartment in Hillcrest
4.91 out of 5 average rating, 100 reviews

Modern home in the heart of SD

This stylish, modern apartment is located in the heart of San Diego's historic Hillcrest neighborhood. Hillcrest has an abundance of restaurants, unique stores, and nightlife venues, many of which are just steps from this home! This one bedroom apartment contains a full kitchen, luxurious walk-in shower, washer & dryer, free off-street parking spot, keyless entry, A/C, Smart TVs, and High-Speed WIFI. It is perfect for a romantic getaway or a fun friend trip to San Diego!

Guest favorite
A spacious lounge area features a large, L-shaped gray couch, a contemporary glass coffee table, and a flat-screen TV mounted on the wall. A fireplace with a dark mantel adds warmth, and light enters through the black-framed windows that lead to a private outdoor space.
Apartment in La Mesa
4.93 out of 5 average rating, 380 reviews

A Little Bit of Luxury in La Mesa! Private & Gated

Relax and stretch out on your king size bed or take a short stroll to La Mesa Village to take in the new shops, bars & restaurants. Enjoy your large lounge with smart tv & fireplace and while away the evening on your fully lit deck. The delights of downtown San Diego, beaches, zoo & airport are only a 15-20 minute drive away. Within walking distance to La Mesa Blvd Tolley stop. Apartment & parking for 1 vehicle is private & gated with plenty of on-street parking.

Top guest favorite
A serene sunset view is captured with soft hues of purple, pink, and orange streaking the sky. Silhouetted hills create a calming backdrop, while the dimming light gently transitions the scenery into evening.
Apartment in Spring Valley
4.89 out of 5 average rating, 184 reviews

Comfy, Cozy Flat With Pool & Spa!

Our flat has a patio that enjoys great sunsets. We are freeway close to all, easy in and easy out!! You’ll love the place because of the comfy bed, space, patio and access to pool and spa. Also, the yard can be enjoyed for relaxing, eating, bonfires, horseshoes and cornhole. An adjoining space is also an AIRBNB studio suite. Great for traveling friends or as an alternative place to consider for your stay. Look for Foemer man Cave with Pool And Spa.

Popular amenities for La Mesa apartment rentals

When is the best time to visit La Mesa?

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Avg. priceﺩ.ﺇ 408ﺩ.ﺇ 393ﺩ.ﺇ 408ﺩ.ﺇ 419ﺩ.ﺇ 419ﺩ.ﺇ 419ﺩ.ﺇ 422ﺩ.ﺇ 404ﺩ.ﺇ 400ﺩ.ﺇ 400ﺩ.ﺇ 422ﺩ.ﺇ 411
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