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House vacation rentals in La Mesa

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Popular amenities for La Mesa house rentals

House rentals with a hot tub

Superhost
An open living space features a modern design with warm wood accents. Two leather chairs are set near a glass coffee table atop a decorative rug. The entrance door stands out with its sleek lines, while the kitchen and a separate room are visible in the background.
Home in University Heights
4.9 out of 5 average rating, 136 reviews

Your Modern Lux Pool Resort in the Heart of SD

KatherineRating, 5 stars3 weeks ago
Wonderful location, 12-14 minutes or less to everything we wanted to do. Expansive patio and pool area. Bedroom layout worked okay for our group of five - three adults and two kids. Property managers were very responsive when we contacted them. The house was spotless. We were there for two weeks and never ran out of things to do in San Diego and environs. We’ll be back.
Guest favorite
A staircase ascends to the rooftop deck, flanked by a smooth, modern wall. A single chair is positioned nearby, while sunlight brightens the space, highlighting the clean lines of the architecture. A door leads to the interior, emphasizing easy access between the indoor and outdoor areas.
Home in Bay Park
4.95 out of 5 average rating, 167 reviews

Modern Home - Rooftop Hot Tub with Ocean Views!

JinghongRating, 5 stars3 weeks ago
Beautiful and modern house, organized supplies and everything. Owner is super responsive and friendly. Very safe and quiet neighborhood. Also Roof top hot tub is always hot and running. Thank you so much for the hospitality! Larissa & Dave
Guest favorite
An outdoor area features a Jacuzzi-brand luxury hot tub with ambient lighting, surrounded by a spacious deck. Cozy seating arrangements include a fire pit and lounge chairs, enhanced by string lights overhead, creating a warm and inviting space for relaxation.
Home in San Diego
4.95 out of 5 average rating, 148 reviews

Canyon View: One-of-a-kind outdoor retreat

RebekahRating, 5 stars2 weeks ago
We had a splendid weekend trip to Elise’s rental. Was the perfect relaxing getaway. The Airbnb was a close drive to attractions and restaurants! The gem of this stay is the backyard. Such a serene atmosphere perfect for couples & families. Would definitely recommend this stay.
Guest favorite
The salt-water pool and spa are illuminated with soft purple lighting, creating a serene atmosphere. Lush plants and well-placed lighting surround the pool area, enhancing the peaceful setting in the evening.
Home in San Carlos
4.87 out of 5 average rating, 186 reviews

Bright and spacious home with views, pool & spa.

Kenicia Rating, 5 stars3 weeks ago
Beautiful home. Great host. Would highly recommend.
Top guest favorite
A modern living space features a large, oval table with circular cutouts, complemented by a green, velvet chair. Colorful abstract artwork adorns the walls, and a ceiling fan hangs above. A window allows for natural light, with greenery visible outside.
Home in University Heights
4.99 out of 5 average rating, 118 reviews

University Heights Oasis Getaway

KelseyRating, 5 stars6 days ago
Great place with a very central location, close to the airport and zoo. We really enjoyed our stay and the amenities offered at the home. Lacee was very responsive and accommodating.
Guest favorite
The living room features a mix of comfortable seating including a light-colored sofa and a leather chair. A central coffee table sits on a soft area rug, while a fireplace is positioned beneath a wall-mounted television. Natural light enters through sliding glass doors.
Home in Paradise Hills
4.95 out of 5 average rating, 213 reviews

Luxury 4-Bed Home - Fantastic Views 15-min from DT

SarahRating, 5 stars2 months ago
I cannot say enough about this place. I loved staying here and would 1000% stay again. Everything was spotless, the view was amazing, I’ve never been more relaxed and at peace. They have everything you could need,everything was thoughtfully put together. If I could give it 10 stars I would.
Guest favorite
A spacious living area features a light-colored sectional sofa arranged around a textured area rug. Large windows allow natural light to fill the room, while a contemporary light fixture hangs from the vaulted ceiling. A flat-screen television is mounted on the wall opposite the seating.
Home in Point Loma Peninsula
4.95 out of 5 average rating, 106 reviews

Luxury Getaway•Hot Tub Harbor Views•Chef’s Kitchen

JessaRating, 5 stars2 weeks ago
We had a long girls’ weekend (a bunch of 40-yr old moms!) - this space was great and had plenty of space. There was a beautiful open living room, kitchen, and dining room. The large window from the kitchen opened so we could have an indoor/outdoor vibe. The yard area was great - plenty of seating and an incredible view. Point Loma and Shelter Island are an easy walk down the hill (going back up is another story!). We had everything we needed - full kitchen to cook, beach towels, etc.
Guest favorite
Home in North Park
4.93 out of 5 average rating, 313 reviews

Charming Mid-Century Craftsman: Hot Tub~Serene Yrd

CharlesRating, 5 stars1 week ago
Tasha’s home was beautiful and located in a beautiful neighborhood. Our family needed a place that would also accommodate our dogs and this was the perfect spot. It is in a great location for walking to restaurants and exploring North Park. Tasha is a perfect host and answered any questions that we had in a timely manner. She was extremely courteous and we would definitely stay at her home again. Highly recommend if you are looking for a great home from which to explore San Diego.

House rentals with free parking

Superhost
An open-concept kitchen and dining area features a spacious bar with four dark stools. Natural light filters through the window, illuminating wood accents on the floor. A small dining table is placed nearby, with artwork displayed on the wall.
Home in North Park
4.83 out of 5 average rating, 126 reviews

Modern Bungalow * Entire Home * Excellent Location

ErinRating, 5 stars1 month ago
Perfect little bungalow for our stay. Comfortable space for our family of three. Loved the original details of the home like the built ins, picture ledges and window transoms. We had everything we needed for the weekend and were close to great restaurants and coffee shops! Lively neighborhood with residents out walking their dogs in the daytime and peaceful quiet in the evening.
Top guest favorite
The spacious living area features a comfortable sofa, a dining table with chairs, and a full kitchen with modern appliances. A front-loading washer and dryer are visible, along with a wall-mounted air conditioning unit. Neutral tones are complemented by natural lighting.
Home in La Mesa
4.96 out of 5 average rating, 525 reviews

Clean 1BR/1BA Guest House Peaceful Private Casita

CesarRating, 5 stars3 days ago
Mihn was a great host and very communicative before check-in and on check-out. The guest house was as described: clean, quiet, and convenient to many great local places. Would definitely recommend this place.
Guest favorite
A two-story house is visible behind a decorative wrought-iron gate. The exterior features a mix of muted colors, with large windows and a well-maintained roof. A spacious driveway can be seen alongside the home, providing ample parking space.
Home in Spring Valley
4.94 out of 5 average rating, 138 reviews

Ac home with lots outside space

AmberRating, 5 stars2 weeks ago
Amazing airbnb with plenty to offer such as 4 beds as well as kitchenwares and toiletries! My friends and I felt right at home with this airbnb. Melissa was great at communicating too, which made the check in and check out processes much easier!
Guest favorite
A spacious studio apartment features a large bed with soft linens and decorative pillows. A sitting area with a cushioned bench provides comfort, while a well-equipped kitchen with modern appliances is visible in the background. Natural light streams through the large window, complemented by stylish curtains.
Home in North Ocean Beach
4.96 out of 5 average rating, 153 reviews

Stunning Ocean Beach Gem - has everything!

RebeccaRating, 5 stars2 weeks ago
Really enjoyed this stay! Didn't know much about ocean beach beforehand so was pleasantly surprised! Lots of places very walkable from airbnb which was awesome. Also, having a parking spot ended up being so convenient. There is a lot of noise from the airplanes and I can be sensitive to light/noise but found myself being able to sleep soundly. I appreciated hosts being upfront about these things in listing so I could accurately choose this place. Would definitely stay again!
Top guest favorite
The exterior of the bungalow features a welcoming entrance with a large covered porch, flanked by vibrant palm trees and landscaped greenery. The property number is clearly displayed, and a wooden fence surrounds the yard, providing a sense of privacy.
Home in Hillcrest
4.98 out of 5 average rating, 361 reviews

Hillcrest 2 bed 2 en-suite baths garage zen garden

JoseRating, 5 stars1 week ago
My friends and I Loved staying here! Would love to be back again! Thanks again!
Superhost
A warm entrance is featured, highlighted by a colorful welcome mat. Steps lead up to a brightly painted door that opens into the home. Potted plants flank the doorway, contributing to a welcoming atmosphere.
Home in Logan Heights
4.96 out of 5 average rating, 157 reviews

4. Family Reunion Historic Sherman Height

IgnatiusRating, 5 stars4 days ago
Sheri’s place is great. She is very nice and reply all our questions.. the place worth the price..
Superhost
A charming duplex is presented, featuring a white exterior with contrasting black accents. The front door is framed by a decorative gate, and a small tree provides shade to the walkway. Neatly trimmed landscaping enhances the inviting atmosphere of the entrance.
Home in Logan Heights
4.92 out of 5 average rating, 270 reviews

🌵King Bed | Queen bed | Full Kitchen | W & D | 1.5Bath | 🌵

KerenRating, 5 stars1 week ago
Anthony was a great host and was very responsive. The home is nice and comfy and perfect for small families especially if you have little ones. The location of the home is perfect. It’s within driving distance to San Diego’s popular spots such as Old Town, zoo, Belmont Park etc. We were able to walk over to Logan Ave. with our little one to check out the arts, small boutiques, and cafes. It was also very helpful to have a parking spot on the property since there’s hardly any parking on the street. My family and I enjoyed our stay and would definitely stay here again.
Superhost
A living area features a modern fireplace paired with stylish seating arranged around a coffee table. Large windows provide natural light, while a dining space with a circular table is visible in the background. Decorative wall art adds subtle character to the room.
Home in San Diego
4.91 out of 5 average rating, 140 reviews

Your Trendy San Diego Home, 2-Car Garage

FernandoRating, 5 stars2 months ago
Absolutely fantastic experience! When emergency repairs forced us out of our home at the last minute, Nathan and Abby were absolute lifesavers. They responded quickly and were incredibly accommodating, allowing us to book their lovely home with virtually no notice. We spent a week there, and it truly felt like a home away from home. The location is amazing so many cute shops and restaurants within walking distance! And the two-car garage was a HUGE bonus, as street parking seemed limited. We highly recommend staying here. Nathan and Abby are amazing hosts, and their home is comfortable, well located, and just what we needed during a stressful time. Thank you both for everything!

House rentals with a pool

Top guest favorite
A serene outdoor space features a curved lounge chair positioned on a wooden deck, overlooking a tranquil pool surrounded by lush greenery. The natural rock formations add texture to the serene atmosphere, while the canopy above provides shade.
Home in North Park
5 out of 5 average rating, 107 reviews

3 BR Urban Oasis with Pool and Spa in Great Area

MonicaRating, 5 stars2 weeks ago
Loved everything about our stay at this amazing house! Comfortable beds, awesome backyard with pool and hot tub, great location- walking distance to restaurants, coffee shops, park and very close to lots of site seeing. Our family of 5 had a wonderful time - thank you for sharing your lovely house with us!
Top guest favorite
A charming single-level home features a vibrant red door and is framed by a low wooden fence. Lush greenery surrounds the front yard, with a driveway leading to a garage on the left. The clear blue sky and sunshine complement the inviting exterior.
Home in Pacific Beach
4.97 out of 5 average rating, 215 reviews

Private 3 bedroom block to Bay New Pool Spa, Bikes

GeorgeRating, 5 stars3 days ago
Vanessa's place is in a very very quiet neighborhood just steps from the bay. I am a SD native, I know the city very well. I actually lived in the area for many years. This place is totally worth it if your traveling with a family with kids. Plenty to do, plenty of space to sit and relax inside and outside. It has plenty of things to keep kids busy from books to toys very very nice touch. If available when we return definitely will be staying here. The short walk to watch the sunset in the ocean is worth every penny..
Top guest favorite
A spacious living area is furnished with comfortable grey couches arranged around a stylish coffee table. A large television is mounted on a stone accent wall, and shelves display decorative items. Natural light filters in through a skylight, enhancing the welcoming ambiance.
Home in El Cajon
4.97 out of 5 average rating, 116 reviews

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa

StephanieRating, 5 stars3 weeks ago
A Perfect Getaway in El Cajon! From the moment we arrived, this stunning Airbnb exceeded all expectations. Nestled in the scenic hills of El Cajon, the property is peaceful, beautifully maintained, and feels like a true retreat. The home itself is immaculate—thoughtfully decorated with a blend of modern touches and cozy charm. Every detail, from the plush linens to the fully stocked kitchen, made us feel pampered and at home. Waking up to the golden California sun streaming through the windows and enjoying coffee on the patio with panoramic views was a daily highlight. The outdoor space is a dream—lush landscaping, a relaxing seating area, and the kind of quiet that lets you truly unwind. Our host was incredibly welcoming and responsive. Whether you’re looking to explore San Diego or just relax in a serene setting, this is the perfect place. We left feeling refreshed, grateful, and already planning our next trip!
Superhost
A backyard pool area is surrounded by tropical palm trees, showcasing a clear, inviting pool with a rock formation. The house, featuring large windows and a spacious deck, serves as a backdrop against a bright blue sky.
Home in Allied Gardens
4.89 out of 5 average rating, 233 reviews

San Diego Retreat / Cal King x 2 / Pool, Parking!

KarenRating, 5 stars2 months ago
House was clean and comfortable. Check in and check out went smoothly. Communication was great with the owner. Perfectly accommodated our family and location was great. We loved that Better Buzz was within walking distance for a coffee! Grocery store and restaurants also close by. Would highly recommend this rental!
Top guest favorite
A modern living area features a light wooden floor complemented by a circular area rug. Seating includes a blue accent chair, a light gray sofa, and a rocking chair. Natural light floods the space through large glass doors, enhancing the minimalist decor.
Home in Mission Hills
4.93 out of 5 average rating, 241 reviews

Lionhead - Private Boutique Home

MarleeRating, 5 stars4 days ago
What a lovely home! We spent 5 days here with our family of 5 and it was absolutely wonderful. The home is spacious and open, very clean, and beautifully decorated. We loved the pool and watching airplanes take off and land in the distance. The neighborhood is very quiet and peaceful. Would stay here again!
Guest favorite
The spacious living area features warm hardwood flooring and a decorative area rug. A large sliding barn door leads to an adjacent room. Natural light fills the space through windows, while a plush armchair and modern floor lamp add to the inviting decor.
Home in Kensington
4.95 out of 5 average rating, 104 reviews

Centrally located Home w/Guest House, Pool & Spa!

KateRating, 5 stars2 weeks ago
We had a great stay over spring break! Our group was 5 adults & 4 children, but we never felt cramped! The neighborhood is charming and felt safe, even to this small town family. We walked into the Kensington main street area most days - for coffee (Starbucks), acai bowls & organic groceries (Stehly Farms Market), pizza, burgers (kids eat free on Tuesday!), and ice cream (you MUST try the Ube & Toffee flavor at Stella Jeans)! :) The kids loved the pool/ hot tub, although it was a shame the pool guy never checked in over our weeklong stay. With 4 children in the pool every day, the water was cloudy by the time we left. I blame myself for not letting Zeina and Mo know, as they were responsive for all my other queries. The casita was a blessing for grandma and grandpa, who needed their quiet time. The only real complaint I heard from our group was that the house smells stale (like the charming old house it is) and the laundry/pingpong area smells of mildew. Opening doors helped!
Superhost
The spacious backyard features a large swimming pool and a hot tub, framed by various palm trees. An outdoor seating area is visible, along with a patio surface that invites relaxation. The area is enclosed by a tall fence, providing privacy.
Home in Chula Vista
4.92 out of 5 average rating, 147 reviews

Modern Oasis - Pool, Spa, Great Location 5BR/4BA

AdrianaRating, 5 stars3 weeks ago
We had a wonderful stay! The house and backyard were incredibly spacious—plenty of room for both kids and pets to play and enjoy themselves. It was such a treat to have both a hot tub and a pool, especially since the weather was on the chillier side during our weekend. The neighbors have dogs, but they were friendly and didn’t bother us or our pup, which we appreciated. We loved that the home was walking distance to a grocery store, a pharmacy, and Hilltop Park which is dog-friendly. The neighborhood itself is very walkable and pet-friendly, something our whole family truly enjoyed. Overall, this was a memorable and comfortable place to stay for our multigenerational family vacation. We’d definitely return!
Superhost
A spacious living area is highlighted by a large sectional sofa, complemented by decorative plants in woven baskets. Natural light fills the space through large windows with light-filtering shades. A dining area and staircase are visible in the background, enhancing the open layout.
Home in Paradise Hills
4.85 out of 5 average rating, 198 reviews

5BR | Salt Water Pool | Hot Tub | Fire Pit| BBQ

HollieRating, 5 stars5 days ago
I love that the kitchen was very well stocked! If you like to cook it’s great! The backyard was beautiful my kids loved the resort feel. We visited for a graduation for my nephew from the Marines boot camp. The location was about 20-25 minutes from base which was so easy because you’re close to the freeway! The house was perfect for our stay! The box truck in the front yard was a throw off when we arrived but once inside you didn’t notice it was there. The house is very cute and full of everything you need to have a great stay! Thank you Brian for being a great host!

Quick stats about house rentals in La Mesa

  • Total rentals

    290 properties

  • Total number of reviews

    12K reviews

  • Family-friendly rentals

    180 properties are a good fit for families

  • Pet-friendly rentals

    90 properties allow pets

  • Rentals with a pool

    70 properties have a pool

  • Rentals with dedicated workspaces

    170 properties have a dedicated workspace

Destinations to explore

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  4. San Diego County
  5. La Mesa
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