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Apartment vacation rentals in Santee

Find and book unique apartments on Airbnb

Quick stats about apartment rentals in Santee

  • Total vacation rentals

    Explore 10 vacation rentals in Santee

  • Nightly prices starting at

    Santee vacation rentals start at ﺩ.ﺇ 551 per night before taxes and fees

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Santee vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santee rentals

Top-rated apartment rentals in Santee

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in Salley
4.99 out of 5 average rating, 118 reviews

The salley house

Freshly renovated store front located in the heart of a friendly southern town. Not to expect luxury, but a spacious, comfy, and clean haven to meet your needs if you are passing through or visiting the area for a few days and need a place to stay while visiting family or eudora farms. It features 2 bedrooms, with two queen beds and a twin trundle. It is a roomy home and has a full kitchen and dining. Master bedroom is on the ground floor, and both bathrooms. Minor step ups on ground floors.

Superhost
A wooden dock extends over the tranquil waters, framed by trees with golden leaves. Boats are visible at the floating slips, surrounded by lush greenery and a peaceful lake setting.
Apartment in Santee
4.79 out of 5 average rating, 28 reviews

Dockside Villa Lake Marion

Dockside Villa on lake Marion includes a boat slip just out the back door of condo. 1 king, 1 Queen: 2 private beds and 2 baths plus pull out sofa bed in living room. Condo is fully furnished which means it will sleep up to six comfortably for a family/friends, golfing-lake adventure. Bring your boat - keep it at the dock during your stay or rent a boat next door. The amenity package includes outdoor grills, walking trails, and a boat landing. 3 world class golf courses are 3 to 5 minutes away.

Guest favorite
The exterior of a single-story, light-colored home is shown, featuring a sloped roof and front steps leading to a welcoming entryway. Lush greenery, including shrubs and trees, surrounds the house, creating a serene environment. A covered porch is visible, enhancing the outdoor space.
Apartment in Orangeburg
4.83 out of 5 average rating, 29 reviews

Cozy and Charming on Raysor

Cozy and comfortable fully furnished one bedroom on quiet street, fenced back yard and off street parking. Living room, Dining room, Office, Modern Kitchen, huge deck table, chairs. WiFi, Internet, TVs, Washer & Dryer. Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged Pets are welcome but there is a pet fee based on number of dogs and breed. Airbnb only charged for 1 pet, we send request for additional pet fees. Some breed are restricted by insurance company.

Top guest favorite
Apartment in Summerville
4.96 out of 5 average rating, 50 reviews

*Azalea Bar•Secret Garden Apt - sleeps 3

Stay in the Heart of Downtown Summerville! Perched above The Azalea, a sophisticated cocktail bar, this historic suite offers the ultimate downtown location and comfort that cannot be beat! Blending modern amenities with southern charm, it’s perfect for those who love being in the center of it all. Step outside & explore all that Flowertown has to offer-eclectic shops & fantastic restaurants or, take a short trip to Charleston & or our fantastic beaches. Book your unforgettable stay today!

Top guest favorite
Apartment in Moncks Corner
5 out of 5 average rating, 40 reviews

Cozy escape studio apartment

Welcome to your perfect little retreat! This cozy studio apartment is nestled in the vibrant heart of our charming small town, just steps away from local shops, cafes, parks, and everything you need for a comfortable visit (See guidebook). We are minutes from several boat ramps on the lake and river listed in the guidebook. We have plenty of space in our driveway for you to bring your boat! 🚤 This is also a perfect extended stay space for traveling nurses and respiratory therapists! 🩺

Top guest favorite
A charming seating area features two high stools paired with a uniquely designed table resembling a vintage Volkswagen front. A wall-mounted television is positioned above a light-colored console. Decorative elements, including a sunflower arrangement, add character to the space.
Apartment in Sumter
4.96 out of 5 average rating, 49 reviews

Cozy Studio Near Downtown

The studio is close to everything, making it easy to plan your visit. Within walking distance of downtown Sumter, enjoy all the amenities that this finished room over garage has to offer. It is located only minutes away from the Sumter Art Museum, world famous Swan Lake, and the Shaw AFB. And you can easily hit the beaches up and down the beautiful coast of South Carolina. You will enjoy the quiet and relaxing atmosphere on one of the tree-lined side streets in the historic district.

Top guest favorite
A spacious efficiency suite features a comfortable queen bed centered against the wall. A light-colored sofa with decorative pillows sits in front, while bedside tables with lamps are placed on either side. Natural light enters through windows, and a view of the bathroom is visible in the background.
Apartment in West Columbia
4.95 out of 5 average rating, 78 reviews

Southern Comfort

This property located on a couple acres of private land near the Columbia Metropolitan Airport. 1 queen bed. Maximum 2 guest, adults only. It's a newly constructed efficiency suite with a full size stove, fridge and comfortaire queen bed. The double french doors open up to a view of the woods where you can enjoy your morning coffee. This property is attached to another efficiency suite, but it separated by an insulated firewall. Concrete floors with Rugs throughout.

Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 174 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Top guest favorite
A single-story brick exterior home is set in a lush green landscape, with well-maintained grass and flower beds in the foreground. A circular driveway leads to a two-car garage. Trees provide shade, contributing to a serene outdoor environment.
Apartment in Summerville
4.99 out of 5 average rating, 110 reviews

The Rustic Roost

Welcome to the Rustic Roost where you can relax and recharge. Located 30 minutes from downtown Charleston, 45 minutes to Isle of Palms, 1hr to Folly Beach. 10 minutes from downtown Summerville, where sweet tea was invented! *Guests who are local to the area may be declined upon request, and require additional questions before approval. **Rustic Roost charges $25 per night for dogs. Please be sure to use the “pets” drop down menu when booking.

Guest favorite
A bright kitchen features wooden countertops and white cabinetry. A dual sink is positioned under a decorative light fixture with hanging bulbs. Wall-mounted shelves display plants and kitchen essentials. Mirrors are framed above the bar area, enhancing light and space.
Apartment in Summerville
4.91 out of 5 average rating, 247 reviews

Full Kitchen, 2 Bed, 2 Bath W/ Laundry & Fish Pond

Hosted by a Superhost with multiple listings in Summerville, this charming, two bedroom, two bathroom apartment features a full kitchen, a washer/dryer combo, and a picturesque 1 acre fishing pond. Resting on a small farm on the outskirts of Summerville, this one-of-a-kind shabby-chic suite will have you in a southern state of mind in no time. Just don't be surprised if you see a chicken or two running around...

Top guest favorite
A spacious bed is dressed with a light patterned duvet and decorative pillows. A black nightstand is positioned beside the bed, topped with a textured lamp and a small potted plant. The backdrop features green wainscoting, adding a calming touch to the room.
Apartment in Barnwell
4.99 out of 5 average rating, 169 reviews

Ellzey Place

Ellzey Place is a peaceful spot where you can relax and unwind. Enjoy having a cup of coffee on the deck facing a spacious private back yard. There are lots of azaleas that bloom in season and pines swaying in the breeze. It is a charming apartment attached to the owner's house but has a private deck and entrance. It has been newly remodeled and delightfully decorated.

Guest favorite
A comfortable seating area is highlighted by a light grey sofa adorned with a patterned throw. Two vintage chairs frame a small coffee table, which is topped with books. Natural light filters through an arched window with a softly shaded blind.
Apartment in Elloree
4.87 out of 5 average rating, 23 reviews

Modern apartment overlooking a Historic Downtown

Relax at this peaceful and centrally-located getaway in the heart of historic Elloree, SC. Just minutes away from Santee, I95, I26, fishing and golfing, it's perfect for a quiet weekend getaway, business trip or staycation! Free electric car charging available for your convenience upon request.

Popular amenities for Santee apartment rentals