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Pet-friendly vacation rentals in Seneca

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Seneca

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
Camper/RV in West Union
4.94 out of 5 average rating, 211 reviews

DogFriendly, Hot Tub, Firepit, Projector, NoChores

WARNING⚠️This place is dangerous! Guests have loved their stays so much that they have threatened to move in! Book a stay at this cozy, tiny, bear themed camper where the covered deck, hot tub, and outdoor projector steal the show, before they do! Your own hideaway sits on a wooded acre just minutes from lakes, waterfalls, and three nearby towns for food, shopping and exploring. End the night by the firepit roasting marshmallows and wondering why you didn't book a longer stay in the first place!

Superhost
The serene lake landscape is painted with vibrant colors at sunset, featuring hues of orange, pink, and purple. The calm water reflects the dramatic sky and surrounding trees, creating a peaceful atmosphere. A dock is visible at the edge of the frame.
Cottage in Townville
4.84 out of 5 average rating, 151 reviews

Waterfront cottage w/deep dock 17 miles to Clemson

Welcome to the Queen of Harts, our 2BR/1BA, waterfront cottage on Lake Hartwell w/private, deep water dock. The house is located on a quite street 25 min to Clemson. Interior has been remodeled including farmhouse kitchen sink, butcher block countertops, dishwasher, large bathroom, washer/dryer, and new furnishings. Enjoy beautiful sunsets on the dock or explore the cove on stand-up paddle boards included with rental. Other amenities include wi-fi, 55" Smart TV, charcoal grill, and fire pit.

Top guest favorite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.88 out of 5 average rating, 118 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Top guest favorite
A cozy bedroom is highlighted by a spacious bed with a patterned blanket. Two bedside lamps provide soft illumination on either side. A wooden dresser is positioned against the wall, and a window allows natural light to fill the space, complemented by cream-colored walls.
Apartment in Seneca
4.94 out of 5 average rating, 178 reviews

Clemson Mom Apartment

Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

Guest favorite
A cozy living area features a stone fireplace flanked by windows, allowing natural light to illuminate the space. A comfortable sofa is arranged around a small table, accompanied by a chair. A TV is mounted above the fireplace for entertainment.
Condo in Salem
4.97 out of 5 average rating, 144 reviews

Beautiful Lake Keowee Condo with great Amenities

"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Top guest favorite
A well-equipped camper kitchen features essential appliances, including a stove and a refrigerator, alongside a spacious countertop. A comfortable reclining sofa sits invitingly, complemented by natural light from the windows that provide a view of the surrounding greenery. A soft area rug adds warmth to the space.
Camper/RV in Salem
4.93 out of 5 average rating, 188 reviews

Camp Glamp at Jocassee

Half a mile from Lake Jocassee is a peaceful hideaway on a private drive. Wake up to birds singing; fall asleep to the sound of crickets and katydids. Enjoy quiet and solitude on a small private deck, then hit the country's most beautiful lake to learn why National Geographic calls the Jocassee Gorges one of "50 of the world's last great places". Waterfalls, wildlife, and the wonder and mystery of Lake Jocassee await you! Then come back to a clean and comfortable 'glamping' experience.

Top guest favorite
A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.
Home in Seneca
4.99 out of 5 average rating, 226 reviews

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

Guest favorite
The screened porch is furnished with a comfortable seating area, including a sectional sofa and side chairs. A decorative rug lies on the floor, and warm light fixtures are suspended from the ceiling. The view offers glimpses of water and surrounding trees.
Cabin in Westminster
4.81 out of 5 average rating, 143 reviews

Lakefront 2BR+/2BA w/ a Dock On Lake Hartwell

Drive right down to your cabin 30ft off water new driveway. Private dock. 2 bathroom. Pet friendly and fence in area. Best view of water with a screen in porch for grilling and seating by water. You will have a hard time finding another place so close to the water. Bar, restaurant tennis, Pickle ball courts basketball and a pool. Ask about fishing trips. Kayaks to use as well. Also please note no rentals to anyone under age of 24. Additionally over 24 must be onsite as well.

Top guest favorite
The exterior of the cabin is framed by lush greenery and a well-maintained lawn. A wooden porch, equipped with swings and rocking chairs, welcomes guests. Twinkling lights hang above, adding to the rustic charm. A stone pathway leads to the entrance, enhancing accessibility.
Guesthouse in Toccoa
4.99 out of 5 average rating, 171 reviews

Cozy Rustic Lakefront Cabin

“on the edge” is a small, cozy, rustic, lakefront cabin with easy walk to a private dock on Lake Hartwell. Great for fishing and swimming. Public boat ramp 2 miles. Living/dining area, two bedrooms. Relax on the large porch with swing and rocking chairs or enjoy fire pit area. No kitchen but includes microwave, full fridge, toaster, Keurig, coffee maker and gas grill. Perfect getaway but also near charming downtown Toccoa, Toccoa Falls, Currahee Mountain, hiking…..

Guest favorite
Tiny home in Pendleton
4.89 out of 5 average rating, 202 reviews

The Rustic Rectangle

Relax at The RR, just 5–15 minutes from Lake Hartwell, Clemson University, Tiger Town shopping, dining, and sunset spots. The space offers a full-bed bedroom, stocked bath, small kitchen, and cozy living area with TV and fireplace. Enjoy the porch, grill, hot tub, outdoor games, and fire pit. Kayaks are available for rent upon request for nearby water access. A peaceful home base perfect for Clemson weekends, lake days, or a quiet getaway.

Top guest favorite
A single-story house with a welcoming porch is surrounded by a manicured lawn. Lush green shrubs and flower beds frame the entrance, complemented by an American flag displayed on the front. The carport is visible to one side, providing additional parking.
Home in Seneca
4.95 out of 5 average rating, 131 reviews

Getaway on Lake Hartwell: Pontoon Rental, Clemson

Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.

Top guest favorite
A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.
Home in Seneca
4.96 out of 5 average rating, 130 reviews

5 Min to Clemson | Large Driveway & Self Check-In

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Popular amenities for Seneca pet-friendly home rentals

When is the best time to visit Seneca?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceﺩ.ﺇ426ﺩ.ﺇ312ﺩ.ﺇ320ﺩ.ﺇ448ﺩ.ﺇ580ﺩ.ﺇ547ﺩ.ﺇ569ﺩ.ﺇ672ﺩ.ﺇ753ﺩ.ﺇ632ﺩ.ﺇ731ﺩ.ﺇ529
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Quick stats about vacation rentals that are pet-friendly in Seneca

  • Total vacation rentals

    Explore 20 vacation rentals in Seneca

  • Nightly prices starting at

    Seneca vacation rentals start at ﺩ.ﺇ184 per night before taxes and fees

  • Verified guest reviews

    Over 1,520 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Seneca vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Seneca rentals

  • 4.9 Average rating

    Seneca stays are highly rated by guests—averaging 4.9 out of 5!