Family-friendly vacation rentals in Seneca

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Seneca

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
Camper/RV in West Union
4.94 out of 5 average rating, 198 reviews

DogFriendly, Hot Tub, Firepit, Projector, NoChores

WARNINGāš ļøThis place is dangerous! Guests have loved their stays so much that they have threatened to move in! Book a stay at this cozy, tiny, bear themed camper where the covered deck, hot tub, and outdoor projector steal the show, before they do! Your own hideaway sits on a wooded acre just minutes from lakes, waterfalls, and three nearby towns for food, shopping and exploring. End the night by the firepit roasting marshmallows and wondering why you didn't book a longer stay in the first place!

Top guest favorite
A charming cottage with a distinctive A-frame structure is set amidst lush greenery. The front yard features well-maintained flower beds, and two benches flank the entrance. An American flag is displayed beside the front door, which is framed by two inviting windows.
Cottage in Anderson
4.96 out of 5 average rating, 113 reviews

A-Frame Lake Hartwell Cottage w/ Hot Tub

No lake water till it substantially rains Lake Hartwell cottage w/ Hot Tub ! Clemson 9 mi. away! 2 bdrm, 2 full bath, hot-tub, canoe, 2kayaks, šŸŽ£ poles, life-vests, dining & patio table, grill+charcoal, 3tv, Netflix/2DVDplayers/DVDs, kitchen, pots/pans, 2crockpot, microwave, dishwasher+pods, keurig+coffee, washer+detergent, dryer, spices, shampoo/cond, hair dryer, curler, straightener, linens, towels, 3bikes, helmet, Karaoke, firepit+wood, wall of fun! (Boat-landing 1 mi. away! Cateechee Shores

Top guest favorite
A vintage camper is positioned under a canopy, offering protection from the elements. An outdoor seating area features a table with a small grill nearby. A stack of firewood is neatly organized beside a fire pit, surrounded by comfortable chairs on a textured surface.
Camper/RV in West Union
4.98 out of 5 average rating, 100 reviews

Nordic Highlands Retreat, 30' Vintage Camper

Peaceful Retreat, - fully restored 30' Vintage Camper situated on a 5 acre private family farm campsite. 25 minutes from Clemson, short drive to the mountains and public access to Lake Keowee. Separate Bedroom. All appliances, cookware, outdoor grill, deck, patio, outdoor wood fire pit (firewood included), and personal amenities. Surrounded by forest with abundant wildlife. 4 season camper with AC & Heat. Great opportunity to savor the camping experience & nearby Lakes & mountain region.

Top guest favorite
The cottage exterior displays warm wood siding with large windows allowing natural light. A welcoming front porch features two chairs and a small plant, while a grill stands nearby. Surrounding landscaping creates a serene atmosphere in a private setting.
Cottage in Central
4.99 out of 5 average rating, 195 reviews

The Wildflower

Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

Top guest favorite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.87 out of 5 average rating, 109 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Guest favorite
A cozy bedroom is highlighted by a spacious bed with a patterned blanket. Two bedside lamps provide soft illumination on either side. A wooden dresser is positioned against the wall, and a window allows natural light to fill the space, complemented by cream-colored walls.
Apartment in Seneca
4.94 out of 5 average rating, 176 reviews

Clemson Mom Apartment

Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

Top guest favorite
A charming cabin is nestled among tall trees, accessed by a stone path. Warm string lights adorn the porch area, creating a welcoming glow. Fallen leaves blanket the ground, complementing the natural surroundings and inviting a sense of tranquility.
Cabin in Pickens
4.98 out of 5 average rating, 244 reviews

The Romantic Greystone Cottage

Follow the enchanting stone path to a private getaway where romance and connection await. Enjoy the ambiance of the starlit sky while cuddled up on the hammock or around the fire. Cozy up on the king-size bed and relish every moment of your stay. Indulge in a bottle of wine and relax by soaking in the luxurious claw-foot tub. Wake up to the tranquil sounds of the forest, savoring the morning with coffee on the porch. Escape the everyday and embrace what matters most at The Greystone Cottage.

Guest favorite
The exterior of a modern camper is displayed, featuring a sleek white exterior with black accents. A set of steps leads to the entrance, and ample surrounding greenery provides a natural backdrop. The driveway is paved, offering easy access.
Camper/RV in Anderson
4.87 out of 5 average rating, 117 reviews

33 Ft Camper perfect for a layover/getaway

Close to Clemson, I- 85, Lake Hartwell, and Anderson. My 2023 Wildwood 28vbxl CAMPER sits in my driveway which is also home to Freedom Fences, a non profit animal rescue. This is a working farm so people are always milling around. Well behaved, housetrained animals allowed but must be crated if left alone. Great spot for Clemson football. 25 minutes to Greenville. 10 minutes from downtown Anderson. Less than 7 miles to Garrison arena. NO Smoking! If you are high maintenance, don't book!

Top guest favorite
A view capturing the entryway leading to a cozy bedroom space. The warm wooden accent wall complements the inviting bedding. A small side table holds a decorative item, while light fills the room through a ceiling fixture, creating a serene atmosphere.
Camper/RV in Pendleton
4.95 out of 5 average rating, 103 reviews

The Pendle-Tin

At the Pendle-tin, you’re close to it all, yet feel tucked away in the west end of downtown Pendleton. You’re 5-8 min from Clemson’s Death Valley, and 2 blocks from downtown Pendleton where you’ll find eateries, and shops. About 5 min from the lake and about 45-50 min from the mountains. Inside you’re Equipped with a kitchen, full bath, WiFi, smart tv , queen bed and separate work space . Outside you have seating for 4 and a propane fire pit.

Top guest favorite
The exterior of a modern tiny house is depicted, featuring a dark blue faƧade and large windows allowing natural light to fill the interior. The covered porch is accessible from the gravel pathway, and greenery surrounds the property, enhancing the wooded setting.
Cottage in Westminster
4.97 out of 5 average rating, 615 reviews

Tiny house

BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

Top guest favorite
A charming tiny house is set amidst wooded surroundings, featuring a welcoming entrance with a white door and a light-colored roof. Two white chairs and a small table are positioned on a wooden porch, complemented by a grill nearby. Lush greenery enhances the tranquil setting.
Tiny home in Seneca
4.96 out of 5 average rating, 244 reviews

Windmill Cottage

You’ll treasure your time at this cute little cottage. It is 295 sq feet and was built in 2023 at the edge of the woods on our property. It has a full kitchen, bedroom with a queen bed, bathroom and living room. It is perfect for one or two people, for either a quiet get-away in the country or for someone who is in town for work and is looking for a more extended stay. We offer discounts for weekly/monthly stays!

Top guest favorite
A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.
Home in Seneca
4.96 out of 5 average rating, 124 reviews

Cozy 3 Br Family Home • 5 min to Clemson Campus

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Popular amenities for Seneca family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Seneca

  • Total vacation rentals

    Explore 50 vacation rentals in Seneca

  • Nightly prices starting at

    Seneca vacation rentals start at ļŗ©.ļŗ‡147 per night before taxes and fees

  • Verified guest reviews

    Over 1,400 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Seneca vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Seneca rentals

  • 4.9 Average rating

    Seneca stays are highly rated by guests—averaging 4.9 out of 5!

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