
Family-friendly vacation rentals in Seneca
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Seneca

Total vacation rentals
Explore 50 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at ﺩ.ﺇ 294 per night before taxes and fees

Verified guest reviews
Over 1,610 verified reviews to help you choose

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
50 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated family-friendly rentals in Seneca
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Destination Keowee
A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Farm Geodome Near Lake Jocassee, Hot Tub, Zip Line
Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

The Wildflower
Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

Clemson Mom Apartment
Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

Cozy Lake House 5 miles from Clemson w Dock
Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

LOFTS OVER MAIN~ Chattooga Studio
Step back in time into this 1890's shop-keepers' homes turned to Lofts Over Main, where you can sleep under the sheets and over the streets. If you love vintage, rustic, yet minimalistic and modern, then come experience 1890's architecture here at the Lofts Over Main. Formerly downtown shop-keepers homes, now the whimsical, upscale lofts are located just minutes from your next adventure. The Lofts were completely renovated in 2017 for guests to enjoy main street living in Walhalla, SC.

Modern & Cozy Cottage-12 min. from Clemson Uni.
Experience South Carolina from this new cottage in Seneca. It's 5 minutes from the Historic Ram Cat Alley with Live Outdoor music every Thursday Night (Apr.-Oct.) Shopping, Boutiques, Restaurants, Breweries, and Coffee Shops. It's only 12 minutes from Clemson University, and a short drive to Lake Keowee, Lake Jocassee, and Lake Hartwell. This area is home to numerous Waterfalls, Hiking Trails, and southern barbecue. If you want a quiet southern getaway, it's the place for you!

Holliday's Inn Tiny Tree-house
Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

Oak Hill Getaway
Right between Seneca and Clemson you will find our getaway. It's 5 mins from Historic Ram Cat Alley with shopping, restaurants, and breweries with Jazz on the Alley music every Thursday night (April - Oct.) It's only 10 minutes from Clemson University. Surrounded by 3 different lakes Jocassee, Keowee, and Hartwell with just a short drive away. You can ride 30 mins up to the mountains where you can hike trails and see waterfalls the foothills have to offer.

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.

Tiny house
BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

Shady Rest
As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.
Popular amenities for Seneca family-friendly rentals
Family-friendly home rentals with a hot tub

Chessie Rails - Caboose w/HotTuB

Keowee Key Luxury Condo - Stunning Views!

Private Hot Tub • Firepit• Projector• Dog Friendly

Hygge Lake House w/ Dock & Hot Tub!

Lake Keowee Cabin: Peaceful and Bright

Lakefront dock *hot tub* Anderson/Clemson king bed

Hidden Lake Sanctuary

Treetop Getaway w/ Hot Tub • Peaceful retreat
Family- and pet-friendly home rentals

Clemson house 1 mile from Campus and Stadium!

Getaway on Lake Hartwell: Pontoon Rental, Clemson

Adjacent to Dawson Park/1 mile from Clemson Univ

The Landing Spot

Secluded Waterfall Cabin.

Hartwell Hideway

Cozy Barndominium Minutes to Clemson & Lake Keowee

Perfect 2 bed, remodeled home in quaint Pendleton
Family-friendly home rentals with a pool

Perfect Tigertown Condo

4br/2ba Great location in heart of Clemson

Lakeside Retreat • Pet friendly • Fire Pit

Lakefront 2BR+/2BA w/ a Dock On Lake Hartwell

Lovely 2-bedroom apartment in welcoming Seneca

Lisa’s Lodge

Near Downtown Greenville + Swamp Rabbit Trail

Beautiful Lake Keowee Condo with great Amenities
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- Clemson University
- Black Rock Mountain State Park
- Gorges State Park
- Table Rock State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Bell Mountain
- Devils Fork State Park
- DuPont State Forest
- Bon Secours Wellness Arena
- Unicoi State Park and Lodge
- Ski Sapphire Valley
- Fred W Symmes Chapel
- Chattooga Belle Farm
- Jump Off Rock
- Looking Glass Falls
- Dillard House Restaurant
- Fluor Field at the West End
- Anna Ruby Falls
- Peace Center
- Jones Gap State Park
- Falls Park On The Reedy
- Dry Falls
- Carl Sandburg Home National Historic Site





