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Vacation rentals in Seneca

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Top-rated vacation rentals in Seneca

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A rustic cabin is surrounded by trees, featuring a spacious porch with a wooden railing. A stone fire pit is situated in front, accompanied by colorful outdoor seating options. The landscape shows a mixture of bare trees and natural ground cover.

Tiny home in Pendleton

4.88 out of 5 average rating, 189 reviews

The Rustic Rectangle

At the RR your close to it all (5-15 by car ) to hartwell lake, tiger town, Clemson university, shopping, restaurants , sunset views etc. Waiting for you back at the space is 1 bedroom featuring a full size bed, 1 bathroom fully stocked, small kitchen w/ pots+pans and a cozy living space with games, dvds, fireplace and tv provided. Outside (H tub currently Out) Enjoy the hot tub, outdoor games, a fire or an afternoon grill out on the porch along w/a bbq grill. Kayaks are available upon request

Top guest favorite

A gravel pathway leads to the front porch of the cabin, lined with decorative outdoor lights. The cabin is framed by tall trees, offering a serene natural setting. The porch features a covered area, inviting guests to enjoy the outdoors.

Cabin in Pickens

4.96 out of 5 average rating, 113 reviews

Hagood Mill Hideaway

Video tour on YouTube "Hagood Mill Hideaway-Air BNB in Upstate South Carolina by Cody Hager Photography". This cabin near Historic Hagood Mill with private fishing pond is perfect for a weekend of relaxing on the porch or while sitting the fire pit. The cabin has a kitchen and gas grill . Smoking, vaping, e‑cigarettes are NOT allowed in the cabin, porch nor the property. We provide a gate pass to Table Rock just 15 min. away. (If the pass is lost during your stay, you will be charged $105 fee)

Top guest favorite

The cottage exterior displays warm wood siding with large windows allowing natural light. A welcoming front porch features two chairs and a small plant, while a grill stands nearby. Surrounding landscaping creates a serene atmosphere in a private setting.

Cottage in Central

4.99 out of 5 average rating, 167 reviews

The Wildflower

Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

Top guest favorite

A cozy bedroom is highlighted by a spacious bed with a patterned blanket. Two bedside lamps provide soft illumination on either side. A wooden dresser is positioned against the wall, and a window allows natural light to fill the space, complemented by cream-colored walls.

Apartment in Seneca

4.95 out of 5 average rating, 170 reviews

Clemson Mom Apartment

Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

A wooden dock extends across the calm water, leading toward a lush green shoreline. The surface of the lake reflects the blue sky, while gentle ripples are visible. Surrounding trees contribute to a serene natural setting.

4.85 out of 5 average rating, 227 reviews

Cozy Lake House 5 miles from Clemson w Dock

Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Top guest favorite

A spacious living area features a large, L-shaped sectional sofa arranged around a coffee table. A kitchenette with wooden cabinets and appliances is visible in the background, while light flows in through patterned curtains, illuminating the cozy sleeping area with a queen-sized bed.

Guest suite in Central

4.97 out of 5 average rating, 181 reviews

Elfwing Carriage House

Bright & comfortable studio apartment located in a quiet family neighborhood in the country, yet minutes to town. We are an easy 15 minute drive to Clemson, less than 5 miles to SWU, 7 miles to Duke Energy. Smart location for the mountains & lakes, visiting colleges, and graduation. Tiger tailgate space available for an additional fee. Hikes, waterfalls, 12 Mile river & Lake Hartwell are nearby. Friendly dogs are fenced or in our home. Come enjoy neighborhood & country living at its finest!

Top guest favorite

A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.

4.99 out of 5 average rating, 211 reviews

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

A charming exterior view of the Tiny Treehouse features a bright red roof and wooden siding with a sunflower design. A picnic table sits on the lawn, surrounded by green grass and trees. A lounging area with rocking chairs is nearby, providing a welcoming outdoor space.

Tiny home in West Union

4.95 out of 5 average rating, 261 reviews

Holliday's Inn Tiny Tree-house

Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

Top guest favorite

The interior space features wooden paneling and a high ceiling, with a spacious bed adorned with a striped blanket. The kitchenette, visible in the background, includes dark cabinets and modern appliances. Soft lighting enhances the cozy ambiance of the room.

Tiny home in Salem

4.97 out of 5 average rating, 117 reviews

The Meadow #4

Take it easy at this unique and tranquil getaway. We ask you to not bring pets due to allergies. We are 4 miles from Fall Creek Landing on Lake Keowee and 8 miles from Lake Jocassee Devils Fork StatePark. The bed is comfortable and the futon is also great for that extra person or children. Grab a drink or a cup of coffee and Sit on the porch or relax in the hammock. Hike our many waterfalls. Self check in anytime after 2:00 pm. Check out is 11:00. Am

Top guest favorite

The exterior of a modern tiny house is depicted, featuring a dark blue façade and large windows allowing natural light to fill the interior. The covered porch is accessible from the gravel pathway, and greenery surrounds the property, enhancing the wooded setting.

Cottage in Westminster

4.97 out of 5 average rating, 572 reviews

Tiny house

BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

The charming house, surrounded by lush greenery, features a screened-in front porch that invites relaxation. A flag gently flutters on the porch, while well-maintained landscaping frames the entrance. Large trees provide ample shade, enhancing the tranquil outdoor environment.

Home in Westminster

4.93 out of 5 average rating, 116 reviews

Shady Rest

As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.

Top guest favorite

A charming tiny house is set amidst wooded surroundings, featuring a welcoming entrance with a white door and a light-colored roof. Two white chairs and a small table are positioned on a wooden porch, complemented by a grill nearby. Lush greenery enhances the tranquil setting.

Tiny home in Seneca

4.96 out of 5 average rating, 212 reviews

Windmill Cottage

You’ll treasure your time at this cute little cottage. It is 295 sq feet and was built in 2023 at the edge of the woods on our property. It has a full kitchen, bedroom with a queen bed, bathroom and living room. It is perfect for one or two people, for either a quiet get-away in the country or for someone who is in town for work and is looking for a more extended stay. We offer discounts for weekly/monthly stays!

Vacation rentals for every style

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Stylish accommodations and amenities

Popular amenities for Seneca vacation rentals

Laptop-friendly workspace

Air conditioning

Other great vacation rentals in Seneca

Top guest favorite

A charming cabin is nestled among trees, featuring a sloped roof and front porch. Two green chairs are placed on a sandy pathway leading to the entrance, inviting relaxation in a serene outdoor setting.

Tiny home in Seneca

5 out of 5 average rating, 76 reviews

Oak Hill Getaway

Top guest favorite

A cozy sleeping area features a spacious bed with white linens and a textured blanket draped across the foot. Natural light enters through a window adorned with a bamboo shade, and a wooden shelf displays decorative items and plants.

Treehouse in Seneca

5 out of 5 average rating, 36 reviews

Treehouse at Keowee Hollow

Top guest favorite

A custom-built cottage is nestled in a natural setting, surrounded by greenery. The structure features warm lighting emanating from windows, complemented by a spacious porch. The surrounding lawn offers ample space, framed by trees that enhance the peaceful atmosphere.

Cabin in Seneca

5 out of 5 average rating, 24 reviews

NEW Creekside Cottage w/ Hot Tub

Top guest favorite

A sign reading 'South Cove Cottage' stands at the foreground, with a well-maintained grassy area surrounding it. In the background, the exterior of the cottage is visible, showcasing a brick facade and large windows framed by trees.

Cottage in Seneca

4.98 out of 5 average rating, 52 reviews

South Cove Cottage ~ Lake Keowee

Top guest favorite

An inviting entrance features a wooden porch with decorative flowers and a bench. A staircase leads to the upper-level apartment, while an American flag adds a patriotic touch. Natural light illuminates the space, creating a welcoming ambiance.

Guesthouse in Seneca

5 out of 5 average rating, 30 reviews

Hartwell Hideway

Top guest favorite

A charming cottage is surrounded by lush greenery and tall trees, featuring a welcoming front porch with seating. The exterior is clad in grey siding and highlights stylish architectural design elements. A gravel driveway leads up to the house, emphasizing its peaceful and private setting.

5 out of 5 average rating, 92 reviews

The Cottage

Top guest favorite

A vintage camper is positioned under a canopy, offering protection from the elements. An outdoor seating area features a table with a small grill nearby. A stack of firewood is neatly organized beside a fire pit, surrounded by comfortable chairs on a textured surface.

Camper/RV in West Union

4.98 out of 5 average rating, 92 reviews

Nordic Highlands Retreat, 30' Vintage Camper

A serene view of the cove showcases calm blue waters bordered by lush greenery and trees. Several boats are docked at a wooden pier, with homes visible along the shoreline. Fluffy clouds drift in a clear blue sky above this tranquil scene.

4.96 out of 5 average rating, 49 reviews

New! Peaceful Lake Keowee Home ~ Near Clemson

Quick stats about vacation rentals in Seneca

Total rentals
50 properties
Nightly prices starting at
ﺩ.ﺇ147 before taxes and fees
Total number of reviews
2.2K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace

Frequently Asked Questions

Where should I stay in Seneca?
Make yourself at home in Seneca by choosing from our most frequently booked neighborhoods. We have over 100 vacation rentals in Utica, and over 180 vacation rentals in Seneca.
Are there vacation rentals with a dedicated workspace in Seneca?
Yes! Work meets play with ease at over 20 vacation rentals in Seneca featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Seneca?
Four-legged friends are welcome in Seneca. Choose from more than 10 vacation rentals for guests traveling with pets.
How much does it cost to stay in house rentals in Seneca?
Experience the best of Seneca with our house rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there family-friendly house rentals in Seneca?
Seneca has more than 20 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do house rentals in Seneca have wireless internet?
Absolutely! We offer over 30 house rentals with wireless internet in Seneca. Enjoy a tailored experience with all the comforts you desire.

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