Lake house vacation rentals in Seneca

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Top-rated lake house rentals in Seneca

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Top guest favorite
Home in Seneca
5 out of 5 average rating, 115 reviews

Lakefront Luxe – Fire Pit, Dock & Views

The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Guest favorite
Home in Westminster
4.94 out of 5 average rating, 287 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Paths for long walks. Architect James Fox designed this cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Top guest favorite
A shaded area features several dark adirondack chairs arranged around a central table, overlooking the serene lake. A large, soft-colored umbrella provides protection from the sun, enhancing the tranquil lakeside setting surrounded by lush greenery.
Home in Martin
4.88 out of 5 average rating, 113 reviews

Lake-House Escape w/Dock, Kayaks, Paddleboards

Gather family or friends for an unforgettable lakeside getaway in a spacious, amenity-loaded lake house in an ultra-private setting. Your group will have a great time on the dock using provided kayaks and paddleboards, fishing, swimming, and more. Bring or rent a boat. Relax on the lakefront screened porch and multiple indoor/outdoor gathering spots. Kids and adults will love watching movies and playing foosball in the game room. Make memories around your choice of beachside or stone firepit.

Guest favorite
A wooden dock extends across the calm water, leading toward a lush green shoreline. The surface of the lake reflects the blue sky, while gentle ripples are visible. Surrounding trees contribute to a serene natural setting.
Home in Seneca
4.85 out of 5 average rating, 242 reviews

Cozy Lake House 5 miles from Clemson w Dock

Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Top guest favorite
A comfortable living room is presented with two sofas, a wooden coffee table, and a rustic stone fireplace. A television rests on a wooden media console, while natural light enters through nearby windows. The flooring is finished in a warm tone, creating an inviting space.
Home in Seneca
4.95 out of 5 average rating, 190 reviews

Private lake setting close to Clemson University

House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

Superhost
Home in Six Mile
4.83 out of 5 average rating, 256 reviews

House on Lake Keowee swim beach in cove w/ Dock

This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Top guest favorite
A single-story home is showcased, featuring a smooth driveway that leads to a covered front porch. Brightly colored chairs are placed on the porch, surrounded by landscaped shrubs. Tall trees provide a lush backdrop, creating a serene and inviting setting.
Home in Seneca
4.97 out of 5 average rating, 158 reviews

Lake Hartwell house w/ dock 2 miles from Clemson.

This is a simple, comfortable, recently renovated home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is next cove over. Clemson golf course across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Top guest favorite
A spacious sunken living area features a large brick fireplace as a central focal point, flanked by two inviting seating arrangements. Natural wood beams extend across the ceiling, and light fills the space through multiple large windows, creating a warm and welcoming environment.
Home in Seneca
4.94 out of 5 average rating, 54 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Top guest favorite
The exterior of the home is illuminated by string lights, creating a warm ambiance. A set of red adirondack chairs is positioned in the foreground, facing the entrance steps. Soft garden lighting highlights the landscaping, enhancing the inviting atmosphere of the outdoor space.
Home in Townville
4.98 out of 5 average rating, 138 reviews

Hartley’s Haven

Enjoy your stay in this cozy 1 bedroom and 1 bathroom home on Lake Hartwell. We are located 20 minutes from Clemson, 15 minutes to Anderson, and 40 minutes to Greenville, so there is plenty in the area to keep you busy. Located on a dead end street, the neighborhood is very quiet. Our home also has fast wifi and 2 smart TV’s to access any streaming service. We also provide cable. With plenty of parking space in the driveway for vehicles and a boat we can provide a peaceful getaway.

Guest favorite
A modern kitchen area features stainless steel appliances, including an oven and microwave. The light cabinetry complements the crisp white backsplash. A large island provides ample counter space, with two stylish barstools positioned nearby. Natural light fills the room through windows, enhancing a bright atmosphere.
Home in West Union
4.93 out of 5 average rating, 122 reviews

Hidden Lake Sanctuary

Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

Guest favorite
An aerial view captures the surrounding area near Lake Hartwell, displaying a cluster of homes nestled among trees. The lake glistens in the sunlight, while the highlighted house includes a distinct blue exterior, harmonizing with the natural landscape.
Home in Martin
5 out of 5 average rating, 12 reviews

The Tiny Giant lake house

Charming 900Sqft lakefront "tiny" house that packs a punch into such a small space! Private bedroom on the main floor along with a full bath, open kitchen, dining and living space with tons of natural light! There is also a loft bedroom that has it's own bathroom with a shower! The bedroom, loft, and main living space all have independently adjustable AC units for maximum comfort! Coming off the back deck it is an easy walk to the swim platform dock.

Guest favorite
A serene view of the lake is captured at sunset, with soft colors reflected on the water. Docked boats line the marina, visible near the shore. The nearby walking path is bordered by lush greenery and softly illuminated by landscape lighting.
Home in Salem
4.98 out of 5 average rating, 148 reviews

Keowee Key Luxury Condo - Stunning Views!

Freshly renovated condo at the sought after Tall Ship condos in Keowee Key. This is hands down the best unit the complex has to offer with amazing views. Enjoy grilling out on the patio overlooking the marina, walking on the trail, or relax in the pool which is only a short walk away. This is truly a paradise. Guest boat slip is available at the marina for boats or jet skis. Slip is $50 per day. Recommended to book one month in advance.

Popular amenities for Seneca lake house rentals