
House vacation rentals in Santo Domingo
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Top-rated house rentals in Santo Domingo
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3 min to Pedasi, 5 min to the Beach, Private Pool!
Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Casa - Domaine De La Rose
Welcome to paradise ! Beautiful home with private pool and a large yard - amazing for entertaining family/ friends 1 master bedroom with full bath with jacuzzi, french doors to terrace 1 queen bed with full bath -1 double/ single bunk bed with full bath Open dining , kitchen and living room Full access to Andromeda Beach Club Full restaurant & bar - always something to do! Massive infinity pool with steps to the Pacific Ocean !! Beach is very beautiful and private and miles to explorer

Peaceful Pedasi
Peaceful Pedasi. Get completely away from the city and forget the rest of the world exists. Pedasí is a town and corregimiento situated on the south-eastern tip of the Azuero Peninsula on Panama’s Pacific coast. And although remote enough to feel protected from the stresses of life, Pedasi offers wonderful dining and shopping. Our home offers a full functioning kitchen, large dining space, 5 Bedrooms, 4 Bathrooms, 2 car garage, private pool, and cabana with your own view of the ocean.

Next to Beach Club: Blue 2 Bedroom Family Villa
Villa 42, one of the closest to the beach in Blue! Kick back, relax in this calm, stylish Villa offering 2 restful bedrooms with comfy Queen beds. Fully equipped kitchen. Spacious lounging terrace. Perfect for couples, families, surfers or digital nomads. Complete amenities. Modern furnishings. WiFi, A/C and Laundry. Only steps away from Blue Venao ocean front beach club and restaurant with infinity pool, the magnificent Pacific Ocean, surfing, dining, activities and nightlife.

NinaHouse, spacious and cool house in Chitré.
House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Country House Like in the City / La Casita
Casa fresca, con árboles, naturaleza y portales p/ descansar, cámaras de seguridad afuera Ubicación céntrica, cerca de malls, restaurantes, buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Contamos con un pozo de agua y sistema de purificación de agua por ósmosis inversa: agua segura, potable y purificada!

Villa La Jungla featuring a New Pool
Escape to this serene, private retreat just minutes from Pedasí, Playa Venao, and stunning beaches. Perfect for 4–8 guests, the home features spacious en-suite bedrooms with quality linens, a fully equipped kitchen, and a newly resurfaced infinity pool. Enjoy total privacy, comfort, and easy access to local adventures. Whether you're here to surf, explore, or relax, this is your ideal home base for a peaceful and memorable stay.

A minimalist Casita in Pedasi
Imagine a peaceful casita with ocean views and a nearby pool house boasting an edgeless pool overlooking the ocean. Plus, you have your own private beach. Inside, you will find an open-concept living space adorned with simple yet stylish furnishings, designed for relaxation and comfort. It's the perfect blend of tranquility, peaceful seclusion and breathtaking natural beauty. Gated community, 24 hour security

Casa Inito - Romantic Getaway
Indulge in the charm of Casa Inito, a thoughtfully crafted haven that invites you to experience a one-bedroom retreat like no other. This well-designed space seamlessly blends modern comfort with an intimate setting, creating the perfect atmosphere for your getaway. The Villa is located just 7 minutes from Playa Venao Beach (by car). ****(Vehicle a MUST, preferably SUV due to steep paved access road)****

House in Plaza Praga - Las Tablas
Céntrica y encantadora casa, ubicada frente a la Plaza Praga, a solo pasos del Parque Belisario Porras y la histórica Iglesia de Santa Librada. Cuenta con 2 habitaciones, cada una con una cama doble, aire acondicionado, agua caliente y tanque de agua y cocina básica. Ideal para alojarte durante Mil Polleras, Carnavales y Semana Santa.
Popular amenities for Santo Domingo house rentals
House rentals with a pool

Yellowfin Casa 3

Chitré Oasis: Modern Home with Private Pool & BBQ

Ocean View, Ocean View El Ciruelo

Beachfront home on Playa Venao + private pool

House in Las Tablas, with a swimming pool and beach access

Casa Del Amor in Pedasi, Panama Oceanfront paradise

Pedasí: Andromeda Boroda 4-6 p. Beach, swimming pool

Casa Carolina: Spacious 3 Bedroom at Blue Venao
Weekly house rentals

Las Casa De Abuelita

Dorado Retreat Farm in Cañas

Beautiful House for Rent in Downtown Chitré

Yayo's Place

Casa Maitri: Panoramic Ocean View, Pool, Near Surf

La casita de Cuca

La Casita 29 of the Villas of San José

Keru's House
Private house rentals

Modern Beach Home with pool and hot tub

House for groups/Perfect for Local Parties

Hacienda Ojo de Agua * Family & Friends Getaway

Two-story house.

Minimalist House In Chitre

rest house

Elegance and comfort in one place

Spacious Condo Heart Playa Venao
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